Characterization of the human mineralocorticoid receptor gene 5'- regulatory region: Evidence for differential hormonal regulation of two alternative promoters via nonclassical mechanisms

Molecular Endocrinology

Volumn 10, Issue 12, 1996, Pages 1549-1560

  Zennaro, Maria Christina ^a,b   Le Menuet, Damien ^a   Lombès, Marc ^a  

^a INSERM   (France)

^b UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; MINERALOCORTICOID; MINERALOCORTICOID RECEPTOR;

ANIMAL CELL; ARTICLE; DNA FLANKING REGION; DNA SEQUENCE; DOSE RESPONSE; EXON; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; HORMONAL REGULATION; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY MECHANISM; SODIUM BALANCE; TRANSCRIPTION REGULATION;

ALDOSTERONE; ALTERNATIVE SPLICING; ANIMALS; BASE SEQUENCE; BINDING SITES; CLONING, MOLECULAR; DEOXYRIBONUCLEASE I; DNA FOOTPRINTING; EXONS; GENE EXPRESSION REGULATION; HUMANS; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); RECEPTORS, GLUCOCORTICOID; RECEPTORS, MINERALOCORTICOID; RECOMBINANT PROTEINS; REGULATORY SEQUENCES, NUCLEIC ACID; SEQUENCE ANALYSIS, DNA; TRANS-ACTIVATION (GENETICS); TRANSFECTION;

ANIMALIA;

EID: 0029908791     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.10.12.1549     Document Type: Article

References (45)

1. Marver D 1985 The mineralocorticoid receptor. In: Litwack J (ed) Biochemical Actions of Hormones. Academic Press Inc, New York, vol 12:385-431
2. Anderson NS, Fanestil DD 1976 Corticoid receptors in rat brain: evidence for an aldosterone receptor. Endocrinology 98:676-684
3. Reul JMHM, de Kloet ER 1985 Two receptor systems for corticosterone in rat brain: microdistribution and differential occupation. Endocrinology 117:2505-2512
4. Armanini D, Strasser T, Weber PC 1985 Characterization of aldosterone binding sites in circulating human mononuclear leukocytes. Am J Physiol E288-E290
5. Pearce P, Funder JW 1987 High affinity aldosterone binding sites (Type I receptors) in rat heart. J Clin Exp Pharmacol Physiol 14:859-866
6. Lombès M, Alfaidy N, Eugene E, Lessana A, Farman N Bonvalet J-P 1995 Prerequisite for cardiac aldosterone action: mineralocorticoid receptor and 11β-hydroxysteroid dehydrogenase in the human heart. Circulation 92:175-182
7. Meyer WJI, Nichols N 1981 Mineralocorticoid binding in cultured smooth muscle cells and fibroblasts from rat aorta. J Steroid Biochem 14:1157-1168
8. Lombès M, Oblin M-E, Gasc JM, Baulieu EE, Farman N, Bonvalet J-P 1992 Immunonistochemical and biochemical evidence for a cardiovascular mineralocorticoid receptor. Circ Res 71:503-510
9. Kenouch S, Lombès M, Delahaye F, Eugène E, Bonvalet J-P, Farman N 1994 Human skin as target for aldosterone: coexpression of mineralocorticoid receptors and 11β-hydroxysteroid dehydrogenase. J Clin Endocrinol Metab 79:1334-1341
10. Evans RM 1988 The steroid and thyroid hormone receptor superfamily. Science 240:889-895
11. Verrey F 1995 Transcriptional control of sodium transport in tight epithelia by adrenal steroids. J Membr Biol 144:93-110
12. Zennaro M-C, Keightley MC, Kotelevtsev Y, Conway G, Soubrier F, Fuller PJ 1995 Human mineralocorticoid receptor genomic structure and identification of expressed isoforms. J Biol Chem 270:21016-21020
13. Kwak SP, Patel PD, Thompson RC, Akil H, Watson SJ 1993 5′-heterogeneity of the mineralocorticoid receptor messenger ribonucleic acid: differential expression and regulation of splice variants within rat hippocampus. Endocrinology 133:2344-2350
14. Trapp T, Rupprecht R, Castrèn M, Reul JMHM, Holsboer F 1994 Heterodimerization between mineralocorticoid and glucocorticoid receptor: a new principle of glucocorticoid action in the CNS. Neuron 13:1457-1462
15. Liu W, Wang J, Sauter NK, Pearce D 1995 Steroid receptor heterodimerization demonstrated in vitro and in vivo. Proc Natl Acad Sci USA 92:12480-12484
16. Lombès M, Binart N, Delahaye F, Baulieu EE, RafestinOblin M-E 1994 Differential intracellular localization of human mineralocorticosteroid receptor on binding of agonist and antagonist. Biochem J 302:191-197
17. Pascal E, Tijan R 1991 Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism. Genes Dev 5:1646-1656
18. Claire M, Oblin M-E, Steiner J-L, Nakane M, Misumi J, Michaud A, Corvol P 1980 Effect of adrenalectomy and aldosterone on the modulation of aldosterone receptors in rat kidney. J Biol Chem 256:142-147
19. Reul JMHM, Pearce PT, Funder JW, Krozowski ZS 1989 Type I and type II corticosteroid receptor gene expression in the rat: effect of adrenalectomy and dexamethasone administration. Mol Endocrinol 3:1674-1680
20. Stephenson G, Funder JW 1987 Hippocampal and renal type I receptors are differentially regulated. Am J Physiol 252:E525-E529
21. Escoubet B, Coureau C, Blot-Chabaud M, Bonvalet J-P, Farman N 1996 Corticosteroid receptor mRNA expression is unaffected by corticosteroids in the rat kidney, heart and colon. Am J Physiol 270:C1343-C1353
22. Meyer AS, Schmidt T 1994 In contrast to glucocorticoid receptors, mineralocorticoid receptors are not auto-regulated in rat distal colon epithelia. Endocrinology 134:1163-1172
23. Castrén M, Trapp T, Berninger B, Castrén E, Holsboer F 1995 Transcriptional induction of rat mineralocorticoid receptor gene in neurones by corticosteroids. J Mol Endocrinol 14:285-293
24. Castrén M, Patchev VK, Almeida OFX, Holsboer F, Trapp T, Castrén E 1995 Regulation of rat mineralocorticoid receptor expression in neurons by progesterone. Endocrinology 136:3800-3806
25. Armanini D, Witzgall H, Wehling M, Kuhle U, Weber PC 1987 Aldosterone receptors in different types of primary hyperaldosteronism. J Clin Endocrinol Metab 65: 101-104
26. Armanini D, Zennaro M-C, Martella L, Scali M, Pratesi C, Grella PV, Mantero F 1992 Mineralocorticoid effector mechanism in preeclampsia. J Clin Endocrinol Metab 74:946-949
27. Castrèn M, Damm K 1993 A functional promoter directing expression of a novel type of rat mineralocorticoid receptor mRNA in brain. J Neuroendocrinol 5:461-466
28. Kato S, Sasaki H, Suzawa M, Masushige S, Tora L, Chambon P, Gronemeyer H 1995 Widely spaced, directly repeated PuGGTCA elements act as promiscuous enhancers for different classes of nuclear receptors. Mol Cell Biol 15:5858-5867
29. Norris J, Fan D, Aleman C, Marks JR, Futreal PA, Wiseman RW, Iglehart JD, Deininger PL, McDonnel DP 1995 Identification of a new subclass of Alu DNA repeats which can function as estrogen receptor-dependent transcriptional enhancers. J Biol Chem 270:22777-22782
30. Sukovich DA, Mukherjee R, Benfield P 1994 A novel, cell-type specific mechanism for estrogen receptor-mediated gene activation in the absence of an estrogen-responsive element. Mol Cell Biol 14:7134-7143
31. Elgort MG, Zou A, Marschke KB, Allegretto EA 1996 Estrogen and estrogen receptor antagonists stimulate transcription from the human retinoic acid receptor-α1 promoter via a novel sequence. Mol Endocrinol 10:477-487
32. Leone TC, Cresci S, Carter ME, Zhang Z, Lala DS, Strauss AW, Kelly DP 1995 The human medium chain acyl-coA dehydrogenase gene promoter consists of a complex arrangement of nuclear receptor response elements and Sp1 binding sites. J Biol Chem 270:16308-16314
33. +-ATPase gene expression in adult and neonatal rat cardiocytes. J Biol Chem 266:12058-12066
34. Whorwood CB, Stewart PM 1995 Transcriptional regulation of Na/K- ATPase by corticosteroids, glycyrrhetinic acid and second messenger pathways in rat kidney epithelial cells. J Mol Endocrinol 15:93-103
35. + channel in colon, lung and kidney. Eur J Physiol 430:299-307
36. Albiston AL, Obeyesekere WR, Smith RE, Krozowski ZS 1994 Cloning and tissue distribution of the human 11beta-hydroxysteroid dehydrogenase type 2 enzyme. Mol Cell Endocrinol 105:R11-17
37. Arriza JL, Weinberger C, Cerelli G, Glaser TM, Handelin BL, Housman DE, Evans RM 1987 Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor. Science 237:268-275
38. Sambrook J, Fritsch EF, Maniatis T 1989 Molecular Cloning. A Laboratory Manual, ed 2. Cold Spring Harbor, NY
39. Prié D, Friedlander G, Coureau C, Vandewalle A, Cassingena R, Ronco PM 1995 Role of adenosine on glucagon-induced cAMP in human collecting duct cell line. Kidney Int 47:1310-1318
40. Graham FL, van der Eb AJ 1973 A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 52:456-467
41. deWet JR, Wood KV, Deluca M, Helsinki DR, Subramani S 1987 Firefly luciferase gene: structure and expression in mammalian cells. Mol Cell Biol 7:725-737
42. Herbomel P, Bourachot B, Yanif M 1984 Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma. Cell 39:653-662
43. Lombès M, Binart N, Oblin M-E, Joulin V, Baulieu EE 1993 Characterization of the interaction of the human mineralocorticosteroid receptor with hormone responsive elements. Biochem J 292:577-583
44. Binart N, Lombès M, Rafestin-Oblin ME, Baulieu EE 1991 Characterization of human mineralocorticosteroid receptor expressed in the baculovirus system. Proc Natl Acad Sci USA 88:10681-10685
45. Cadepond F, Binart N, Chambraud B, Jibard N, Schweizer-Groyer G, Segard-Maurel I, Baulieu EE 1993 Interaction of glucocorticosteroid receptor and wild type or mutated 90-kDa heat shock protein coexpressed in baculovirus-infected Sf9 cells. Proc Natl Acad Sci USA 90:10434-10438