Low renal mineralocorticoid receptor expression at birth contributes to partial aldosterone resistance in neonates

Endocrinology

Volumn 150, Issue 9, 2009, Pages 4414-4424

  Martinerie, Laetitia ^a,b   Viengchareun, Say ^a,b   Delezoide, Anne Lise ^c   Jaubert, Francis ^d   Sinico, Martine ^e   Prevot, Sophie ^f   Boileau, Pascal ^f   Meduri, Geri ^a,b,g   Lombes, Marc ^a,b,g  

^a INSERM   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c HÔPITAL ROBERT DEBRÉ   (France)

^d HÔPITAL NECKER ENFANTS MALADES   (France)

^e CENTRE HOSPITALIER INTERCOMMUNAL DE CRÉTEIL   (France)

^f HÔPITAL ANTOINE BÉCLÈRE   (France)

^g BICÊTRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 2; ALDOSTERONE; AQUAPORIN 2; EPITHELIAL SODIUM CHANNEL; GLUCOCORTICOID RECEPTOR; MINERALOCORTICOID RECEPTOR; RENIN; VASOPRESSIN RECEPTOR;

ALDOSTERONE BLOOD LEVEL; ANIMAL TISSUE; ARTICLE; FEMALE; HORMONE RESISTANCE; HUMAN; HUMAN EXPERIMENT; IMMUNOHISTOCHEMISTRY; KIDNEY DEVELOPMENT; MALE; MOUSE; NEWBORN; NONHUMAN; NORMAL HUMAN; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UMBILICAL CORD BLOOD;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2; ALDOSTERONE; ANIMALS; AQUAPORIN 2; DRUG RESISTANCE; EPITHELIAL SODIUM CHANNEL; FEMALE; HUMANS; INFANT, NEWBORN; KIDNEY; MALE; MICE; RECEPTORS, GLUCOCORTICOID; RECEPTORS, MINERALOCORTICOID; RECEPTORS, VASOPRESSIN; RENIN; RENIN-ANGIOTENSIN SYSTEM;

EID: 69249136736     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2008-1498     Document Type: Article

References (42)

1. Holtbäck U, Aperia AC 2003 Molecular determinants of sodium and water balance during early human development. Semin Neonatol 8:291-299
2. Aperia A, Broberger O, Herin P, Zetterström R 1979 Sodium excretion in relation to sodium intake and aldosterone excretion in newborn pre-term and full-term infants. Acta Paediatr Scand 68:813-817
3. Mehta KP, Karnik SR, Sathe A, Pant R, Khatwani R, Bhise A 1992 Renal parameters during infancy. Indian Pediatr 29:1385-1390
4. Dolezel Z, Starha J, Novotna D, Dostalkova D 2004 Secondary pseudohypoaldosteronism in an infant with pyelonephritis. Bratisl Lek Listy 105:435-437
5. Maruyama K, Watanabe H, Onigata K 2002 Reversible secondary pseudohypoaldosteronism due to pyelonephritis. Pediatr Nephrol 17:1069-1070
6. Viengchareun S, Le Menuet D, Martinerie L, Munier M, Pascual-Le Tallec L, Lombès M 2007 The mineralocorticoid receptor: insights in its molecular and (patho)physiological biology. Nucl Recept Signal 5:e012
7. Morrison N, Harrap SB, Arriza JL, Boyd E, Connor JM 1990 Regional chromosomal assignment of the human mineralocorticoid receptor gene to 4q31.1. Hum Genet 85:130-132
8. Zennaro MC, Keightley MC, Kotelevtsev Y, Conway GS, Soubrier F, Fuller PJ 1995 Human mineralocorticoid receptor genomic structure and identification of expressed isoforms. J Biol Chem 270:21016-21020
9. Zennaro MC, Farman N, Bonvalet JP, Lombès M 1997 Tissue-specific expression of α and β messenger ribonucleic acid isoforms of the human mineralocorticoid receptor in normal and pathological states. J Clin Endocrinol Metab 82:1345-1352
10. Mick VE, Itani OA, Loftus RW, Husted RF, Schmidt TJ, Thomas CP 2001 The α-subunit of the epithelial sodium channel is an aldosterone-induced transcript in mammalian collecting ducts, and this transcriptional response is mediated via distinct cis-elements in the 5′-flanking region of the gene. Mol Endocrinol 15:575-588
11. Derfoul A, Robertson NM, Lingrel JB, Hall DJ, Litwack G 1998 Regulation of the human Na/K-ATPase β1 gene promoter by mineralocorticoid and glucocorticoid receptors. J Biol Chem 273:20702-20711
12. Hasler U, Mordasini D, Bianchi M, Vandewalle A, Féraille E, Martin PY 2003 Dual influence of aldosterone on AQP2 expression in cultured renal collecting duct principal cells. J Biol Chem 278:21639-21648
13. Edwards CR, Stewart PM, Burt D, Brett L, McIntyre MA, Sutanto WS, de Kloet ER, Monder C 1988 Localisation of 11β-hydroxysteroid dehydrogenase: tissue specific protector of the mineralocorticoid receptor. Lancet 2:986-989
14. Funder JW, Pearce PT, Smith R, Smith AI 1988 Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated. Science 242:583-585
15. Hayashi M, Sasaki S, Tsuganezawa H, Monkawa T, Kitajima W, Konishi K, Fushimi K, Marumo F, Saruta T 1996 Role of vasopressin V2 receptor in acute regulation of aquaporin-2. Kidney Blood Press Res 19:32-37
16. Kuure S, Vuolteenaho R, Vainio S 2000 Kidney morphogenesis: cellular and molecular regulation. Mech Dev 92:31-45
17. Gomez-Sanchez CE, de Rodriguez AF, Romero DG, Estess J, Warden MP, Gomez-Sanchez MT, Gomez-Sanchez EP 2006 Development of a panel of monoclonal antibodies against the mineralocorticoid receptor. Endocrinology 147:1343-1348
18. Fischer E, Legue E, Doyen A, Nato F, Nicolas JF, Torres V, Yaniv M, Pontoglio M 2006 Defective planar cell polarity in polycystic kidney disease. Nat Genet 38:21-23
19. Ostrowski NL, Young 3rd WS, Knepper MA, Lolait SJ 1993 Expression of vasopressin V1a and V2 receptor messenger ribonucleic acid in the liver and kidney of embryonic, developing, and adult rats. Endocrinology 133:1849-1859
20. Yamamoto T, Sasaki S, Fushimi K, Ishibashi K, Yaoita E, Kawasaki K, Fujinaka H, Marumo F, Kihara I 1997 Expression of AQP family in rat kidneys during development and maturation. Am J Physiol 272:F198-F204
21. Thony HC, Luethy CM, Zimmermann A, Laux-End R, Oetliker OH, Bianchetti MG 1995 Histological features of glomerular immaturity in infants and small children with normal or altered tubular function. Eur J Pediatr 154:S65-68
22. Moll R, Franke WW, Schiller DL, Geiger B, Krepler R 1982 The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell 31:11-24
23. Battifora H 1991 Assessment of antigen damage in immunohistochemistry. The vimentin internal control. Am J Clin Pathol 96:669-671
24. Booth RE, Johnson JP, Stockand JD 2002 Aldosterone. Adv Physiol Educ 26:8-20
25. Brown RW, Diaz R, Robson AC, Kotelevtsev YV, Mullins JJ, Kaufman MH, Seckl JR 1996 The ontogeny of 11β-hydroxysteroid dehydrogenase type 2 and mineralocorticoid receptor gene expression reveal intricate control of glucocorticoid action in development. Endocrinology 137:794-797
26. Condon J, Gosden C, Gardener D, Nickson P, Hewison M, Howie AJ, Stewart PM 1998 Expression of type 2 11β-hydroxysteroid dehydrogenase and corticosteroid hormone receptors in early human fetal life. J Clin Endocrinol Metab 83:4490-4497
27. Hirasawa G, Sasano H, Suzuki T, Takeyama J, Muramatu Y, Fukushima K, Hiwatashi N, Toyota T, Nagura H, Krozowski ZS 1999 11β-Hydroxysteroid dehydrogenase type 2 and mineralocorticoid receptor in human fetal development. J Clin Endocrinol Metab 84:1453-1458
28. Modena AB, Fieni S 2004 Amniotic fluid dynamics. Acta Biomed 75(Suppl 1):11-13
29. Ouellet T, Lussier M, Babaï F, Lapointe L, Royal A 1990 Differential expression of the epidermal K1 and K10 keratin genes during mouse embryo development. Biochem Cell Biol 68:448-453
30. Cheung CY, Brace RA 2005 Amniotic fluid volume and composition in mouse pregnancy. J Soc Gynecol Investig 12:558-562
31. Kiilerich P, Kristiansen K, Madsen SS 2007 Hormone receptors in gills of smolting Atlantic salmon, Salmo salar: expression of growth hormone, prolactin, mineralocorticoid and glucocorticoid receptors and 11β-hydroxysteroid dehydrogenase type 2. Gen Comp Endocrinol 152:295-303
32. Geller DS, Zhang J, Zennaro MC, Vallo-Boado A, Rodriguez-Soriano J, Furu L, Haws R, Metzger D, Botelho B, Karaviti L, Haqq AM, Corey H, Janssens S, Corvol P, Lifton RP 2006 Autosomal dominant pseudohypoaldosteronism type 1: mechanisms, evidence for neonatal lethality, and phenotypic expression in adults. J Am Soc Nephrol 17:1429-1436
33. + metabolism. Proc Natl Acad Sci USA 95:9424-9429
34. Hubert C, Gasc JM, Berger S, Schütz G, Corvol P 1999 Effects of mineralocorticoid receptor gene disruption on the components of the renin-angiotensin system in 8-day-old mice. Mol Endocrinol 13:297-306
35. Zennaro MC, Le Menuet D, Lombès M 1996 Characterization of the human mineralocorticoid receptor gene 5′-regulatory region: evidence for differential hormonal regulation of two alternative promoters via nonclassical mechanisms. Mol Endocrinol 10:1549-1560
36. Le Menuet D, Viengchareun S, Penfornis P, Walker F, Zennaro MC, Lombès M 2000 Targeted oncogenesis reveals a distinct tissue-specific utilization of alternative promoters of the human mineralocorticoid receptor gene in transgenic mice. J Biol Chem 275:7878-7886
37. Bleich M, Warth R, Schmidt-Hieber M, Schulz-Baldes A, Hasselblatt P, Fisch D, Berger S, Kunzelmann K, Kriz W, Schütz G, Greger R 1999 Rescue of the mineralocorticoid receptor knock-out mouse. Pflugers Arch 438:245-254
38. de Seigneux S, Nielsen J, Olesen ET, Dimke H, Kwon TH, Frøkiaer J, Nielsen S 2007 Long-term aldosterone treatment induces decreased apical but increased basolateral expression of AQP2 in CCD of rat kidney. Am J Physiol Renal Physiol 293:F87-F99
39. Le Menuet D, Isnard R, Bichara M, Viengchareun S, Muffat-Joly M, Walker F, Zennaro MC, Lombès M 2001 Alteration of cardiac and renal functions in transgenic mice overexpressing human mineralocorticoid receptor. J Biol Chem 276:38911-38920
40. Wang X, Skelley L, Cade R, Sun Z 2006 AAV delivery of mineralocorticoid receptor shRNA prevents progression of cold-induced hypertension and attenuates renal damage. Gene Ther 13:1097-1103
41. Quinkler M, Zehnder D, Eardley KS, Lepenies J, Howie AJ, Hughes SV, Cockwell P, Hewison M, Stewart PM 2005 Increased expression of mineralocorticoid effector mechanisms in kidney biopsies of patients with heavy proteinuria. Circulation 112:1435-1443
42. Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Perez A, Palensky J, Wittes J 1999 The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 341:709-717