SOX2, a predictor of survival in gastric cancer, inhibits cell proliferation and metastasis by regulating PTEN

Cancer Letters

Volumn 358, Issue 2, 2015, Pages 210-219

  Wang, Simeng ^a   Tie, Jun ^a   Wang, Rui ^a   Hu, Fengrong ^a   Gao, Liucun ^b   Wang, Wenlan ^c   Wang, Lifeng ^c   Li, Zengshan ^a   Hu, Sijun ^a   Tang, Shanhong ^a   Li, Mengbin ^a   Wang, Xin ^a   Nie, Yongzhan ^a   Wu, Kaichun ^a   Fan, Daiming ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Gastric cancer; Prognostic indicator; PTEN; SOX2; Tumor metastasis

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR SOX2; SOX2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR SOX;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CHROMATIN IMMUNOPRECIPITATION DNA SELECTION AND LIGATION; CHROMATIN IMMUNOPRECIPITATION POLYMERASE CHAIN REACTION; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA MICROARRAY; FEMALE; GAIN OF FUNCTION MUTATION; GEL MOBILITY SHIFT ASSAY; GENE CONTROL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCHEMISTRY; LOSS OF FUNCTION MUTATION; LUCIFERASE ASSAY; MAJOR CLINICAL STUDY; MALE; METASTASIS INHIBITION; MIDDLE AGED; MOUSE; NONHUMAN; NUCLEIC ACID ANALYSIS; POLYMERASE CHAIN REACTION; PROTEIN BLOOD LEVEL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; PTEN GENE; SIGNAL TRANSDUCTION; STOMACH CANCER; SURVIVAL PREDICTION; SURVIVAL TIME; TRANSCRIPTION REGULATION; UPREGULATION; AGED; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; METASTASIS; MORTALITY; PATHOLOGY; PROGNOSIS; STOMACH TUMOR; TUMOR VOLUME;

ADULT; AGED; APOPTOSIS; CELL PROLIFERATION; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MIDDLE AGED; NEOPLASM METASTASIS; NEOPLASM STAGING; PROGNOSIS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; SOXB1 TRANSCRIPTION FACTORS; STOMACH NEOPLASMS; TUMOR BURDEN;

EID: 84921605902     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.12.045     Document Type: Article

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