Helicobacter pylori induces gastric mucosal intestinal metaplasia through the inhibition of interleukin-4-mediated HMG box protein Sox2 expression

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 297, Issue 2, 2009, Pages

  Asonuma, Sho ^a   Imatani, Akira ^a   Asano, Naoki ^a   Oikawa, Tomoyuki ^a   Konishi, Hidetomo ^a   Iijima, Katsunori ^a   Koike, Tomoyuki ^a   Ohara, Shuichi ^a   Shimosegawa, Tooru ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Cdx2; STAT6 signaling; Transdifferentiation

Indexed keywords

CYTOKINE; GAMMA INTERFERON; HIGH MOBILITY GROUP PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 4; MUCIN 2; RNA; STAT6 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CDX2; TRANSCRIPTION FACTOR SOX2; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BACTERIAL GROWTH; CELL TRANSDIFFERENTIATION; CONTROLLED STUDY; EPITHELIUM CELL; GEL MOBILITY SHIFT ASSAY; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INTESTINE METAPLASIA; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; STOMACH CANCER; STOMACH CARCINOGENESIS; STOMACH EPITHELIUM; STOMACH MUCOSA; WESTERN BLOTTING;

BASE SEQUENCE; BINDING SITES; CELL TRANSDIFFERENTIATION; DOWN-REGULATION; GASTRIC MUCOSA; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; INTERFERON-GAMMA; INTERLEUKIN-1BETA; INTERLEUKIN-4; KI-67 ANTIGEN; METAPLASIA; MOLECULAR SEQUENCE DATA; MUCIN-2; PARIETAL CELLS, GASTRIC; PHOSPHORYLATION; PRECANCEROUS CONDITIONS; PROMOTER REGIONS, GENETIC; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SOXB1 TRANSCRIPTION FACTORS; STAT6 TRANSCRIPTION FACTOR; STOMACH NEOPLASMS; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 68049090024     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00518.2007     Document Type: Article

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