Probes to monitor activity of the paracaspase MALT1

Chemistry and Biology

Volumn 22, Issue 1, 2015, Pages 139-147

  Hachmann, Janna ^a   Edgington Mitchell, Laura E ^b   Poreba, Marcin ^c   Sanman, Laura E ^b   Drag, Marcin ^c   Bogyo, Matthew ^b   Salvesen, Guy S ^a  

^a BURNHAM INSTITUTE   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c WROCLAW UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1; UNCLASSIFIED DRUG; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MALT1 PROTEIN, HUMAN; MOLECULAR PROBE; PROTEIN BINDING; RECOMBINANT PROTEIN; TUMOR PROTEIN;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; BIOSYNTHESIS; CHEMISTRY; GENETIC TRANSFECTION; GENETICS; HEK293 CELL LINE; KINETICS; METABOLISM; MOLECULAR PROBE; MUTATION; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

CASPASES; CELL LINE, TUMOR; HEK293 CELLS; HUMANS; KINETICS; MOLECULAR PROBES; MUTATION; NEOPLASM PROTEINS; NF-KAPPA B; PROTEIN BINDING; PROTEOLYSIS; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84921527332     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2014.11.011     Document Type: Article

References (48)

1. T. Akagi, M. Motegi, A. Tamura, R. Suzuki, Y. Hosokawa, H. Suzuki, H. Ota, S. Nakamura, Y. Morishima, M. Taniwaki, and M. Seto A novel gene, MALT1 at 18q21, is involved in t(11;18) (q21;q21) found in low-grade B-cell lymphoma of mucosa-associated lymphoid tissue Oncogene 18 1999 5785 5794
2. A.J. Barrett, A.A. Kembhavi, M.A. Brown, H. Kirschke, C.G. Knight, M. Tamai, and K. Hanada L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L Biochem. J. 201 1982 189 198
3. A.B. Berger, K.B. Sexton, and M. Bogyo Commonly used caspase inhibitors designed based on substrate specificity profiles lack selectivity Cell Res. 16 2006 961 963
4. K. Cabalzar, C. Pelzer, A. Wolf, G. Lenz, J. Iwaszkiewicz, V. Zoete, S. Hailfinger, and M. Thome Monoubiquitination and activity of the paracaspase MALT1 requires glutamate 549 in the dimerization interface PLoS ONE 8 2013 e72051
5. T. Che, Y. You, D. Wang, M.J. Tanner, V.M. Dixit, and X. Lin MALT1/paracaspase is a signaling component downstream of CARMA1 and mediates T cell receptor-induced NF-kappaB activation J. Biol. Chem. 279 2004 15870 15876
6. B. Coornaert, M. Baens, K. Heyninck, T. Bekaert, M. Haegman, J. Staal, L. Sun, Z.J. Chen, P. Marynen, and R. Beyaert T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20 Nat. Immunol. 9 2008 263 271
7. J. Dierlamm, M. Baens, I. Wlodarska, M. Stefanova-Ouzounova, J.M. Hernandez, D.K. Hossfeld, C. De Wolf-Peeters, A. Hagemeijer, H. Van den Berghe, and P. Marynen The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas Blood 93 1999 3601 3609
8. L.E. Edgington, M. Verdoes, A. Ortega, N.P. Withana, J. Lee, S. Syed, M.H. Bachmann, G. Blum, and M. Bogyo Functional imaging of legumain in cancer using a new quenched activity-based probe J. Am. Chem. Soc. 135 2013 174 182
9. A.C. Eitelhuber, O. Vosyka, D. Nagel, M. Bognar, D. Lenze, K. Lammens, F. Schlauderer, D. Hlahla, K.-P. Hopfner, and G. Lenz Activity-based probes for detection of active MALT1 paracaspase in immune cells and lymphomas Chem Biol. 22 2014 129 138 this issue
10. U. Ferch, B. Kloo, A. Gewies, V. Pfänder, M. Düwel, C. Peschel, D. Krappmann, and J. Ruland Inhibition of MALT1 protease activity is selectively toxic for activated B cell-like diffuse large B cell lymphoma cells J. Exp. Med. 206 2009 2313 2320
11. O. Gaide, B. Favier, D.F. Legler, D. Bonnet, B. Brissoni, S. Valitutti, C. Bron, J. Tschopp, and M. Thome CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-kappa B activation Nat. Immunol. 3 2002 836 843
12. C. Guiet, and P. Vito Caspase recruitment domain (CARD)-dependent cytoplasmic filaments mediate bcl10-induced NF-kappaB activation J. Cell Biol. 148 2000 1131 1140
13. J. Hachmann, S.J. Snipas, B.J. van Raam, E.M. Cancino, E.J. Houlihan, M. Poreba, P. Kasperkiewicz, M. Drag, and G.S. Salvesen Mechanism and specificity of the human paracaspase MALT1 Biochem. J. 443 2012 287 295
14. S. Hailfinger, G. Lenz, V. Ngo, A. Posvitz-Fejfar, F. Rebeaud, M. Guzzardi, E.M. Penas, J. Dierlamm, W.C. Chan, L.M. Staudt, and M. Thome Essential role of MALT1 protease activity in activated B cell-like diffuse large B-cell lymphoma Proc. Natl. Acad. Sci. USA 106 2009 19946 19951
15. S. Hailfinger, H. Nogai, C. Pelzer, M. Jaworski, K. Cabalzar, J.E. Charton, M. Guzzardi, C. Décaillet, M. Grau, and B. Dörken Malt1-dependent RelB cleavage promotes canonical NF-kappaB activation in lymphocytes and lymphoma cell lines Proc. Natl. Acad. Sci. USA 108 2011 14596 14601
16. P.G. Isaacson, and M.Q. Du MALT lymphoma: from morphology to molecules Nat. Rev. Cancer 4 2004 644 653
17. K. Izumiyama, M. Nakagawa, M. Yonezumi, Y. Kasugai, R. Suzuki, H. Suzuki, S. Tsuzuki, Y. Hosokawa, M. Asaka, and M. Seto Stability and subcellular localization of API2-MALT1 chimeric protein involved in t(11;18) (q21;q21) MALT lymphoma Oncogene 22 2003 8085 8092
18. K.M. Jeltsch, D. Hu, S. Brenner, J. Zöller, G.A. Heinz, D. Nagel, K.U. Vogel, N. Rehage, S.C. Warth, and S.L. Edelmann Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote TH17 differentiation Nat. Immunol. 15 2014 1079 1089
19. D. Kato, K.M. Boatright, A.B. Berger, T. Nazif, G. Blum, C. Ryan, K.A. Chehade, G.S. Salvesen, and M. Bogyo Activity-based probes that target diverse cysteine protease families Nat. Chem. Biol. 1 2005 33 38
20. D. Kato, S.H. Verhelst, K.B. Sexton, and M. Bogyo A general solid phase method for the preparation of diverse azapeptide probes directed against cysteine proteases Org. Lett. 7 2005 5649 5652
21. R.L. Lamason, R.R. McCully, S.M. Lew, and J.L. Pomerantz Oncogenic CARD11 mutations induce hyperactive signaling by disrupting autoinhibition by the PKC-responsive inhibitory domain Biochemistry 49 2010 8240 8250
22. G. Lenz, R.E. Davis, V.N. Ngo, L. Lam, T.C. George, G.W. Wright, S.S. Dave, H. Zhao, W. Xu, and A. Rosenwald Oncogenic CARD11 mutations in human diffuse large B cell lymphoma Science 319 2008 1676 1679
23. P.C. Lucas, M. Yonezumi, N. Inohara, L.M. McAllister-Lucas, M.E. Abazeed, F.F. Chen, S. Yamaoka, M. Seto, and G. Nunez Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway J. Biol. Chem. 276 2001 19012 19019
24. J.A. Morgan, Y. Yin, A.D. Borowsky, F. Kuo, N. Nourmand, J.I. Koontz, C. Reynolds, L. Soreng, C.A. Griffin, and F. Graeme-Cook Breakpoints of the t(11;18)(q21;q21) in mucosa-associated lymphoid tissue (MALT) lymphoma lie within or near the previously undescribed gene MALT1 in chromosome 18 Cancer Res. 59 1999 6205 6213
25. D. Nagel, S. Spranger, M. Vincendeau, M. Grau, S. Raffegerst, B. Kloo, D. Hlahla, M. Neuenschwander, J. Peter von Kries, and K. Hadian Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC-DLBCL Cancer Cell 22 2012 825 837
26. A. Oeckinghaus, E. Wegener, V. Welteke, U. Ferch, S.C. Arslan, J. Ruland, C. Scheidereit, and D. Krappmann Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation EMBO J. 26 2007 4634 4645
27. C. Pelzer, K. Cabalzar, A. Wolf, M. Gonzalez, G. Lenz, and M. Thome The protease activity of the paracaspase MALT1 is controlled by monoubiquitination Nat. Immunol. 14 2013 337 345
28. J.L. Pomerantz, E.M. Denny, and D. Baltimore CARD11 mediates factor-specific activation of NF-kappaB by the T cell receptor complex EMBO J. 21 2002 5184 5194
29. J.C. Powers, J.L. Asgian, O.D. Ekici, and K.E. James Irreversible inhibitors of serine, cysteine, and threonine proteases Chem. Rev. 102 2002 4639 4750
30. Q. Qiao, C. Yang, C. Zheng, L. Fontán, L. David, X. Yu, C. Bracken, M. Rosen, A. Melnick, E.H. Egelman, and H. Wu Structural architecture of the CARMA1/Bcl10/MALT1 signalosome: nucleation-induced filamentous assembly Mol. Cell 51 2013 766 779
31. L. Qiu, and S. Dhe-Paganon Oligomeric structure of the MALT1 tandem Ig-like domains PLoS ONE 6 2011 e23220
32. F. Rebeaud, S. Hailfinger, A. Posevitz-Fejfar, M. Tapernoux, R. Moser, D. Rueda, O. Gaide, M. Guzzardi, E.M. Iancu, and N. Rufer The proteolytic activity of the paracaspase MALT1 is key in T cell activation Nat. Immunol. 9 2008 272 281
33. S. Rosebeck, L. Madden, X. Jin, S. Gu, I.J. Apel, A. Appert, R.A. Hamoudi, H. Noels, X. Sagaert, and P. Van Loo Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation Science 331 2011 468 472
34. J.S. Rossman, N.G. Stoicheva, F.D. Langel, G.H. Patterson, J. Lippincott-Schwartz, and B.C. Schaefer POLKADOTS are foci of functional interactions in T-Cell receptor-mediated signaling to NF-kappaB Mol. Biol. Cell 17 2006 2166 2176
35. A.A. Ruefli-Brasse, D.M. French, and V.M. Dixit Regulation of NF-kappaB-dependent lymphocyte activation and development by paracaspase Science 302 2003 1581 1584
36. J. Ruland, G.S. Duncan, A. Wakeham, and T.W. Mak Differential requirement for Malt1 in T and B cell antigen receptor signaling Immunity 19 2003 749 758
37. B.C. Schaefer, J.W. Kappler, A. Kupfer, and P. Marrack Complex and dynamic redistribution of NF-kappaB signaling intermediates in response to T cell receptor stimulation Proc. Natl. Acad. Sci. USA 101 2004 1004 1009
38. F. Schlauderer, K. Lammens, D. Nagel, M. Vincendeau, A.C. Eitelhuber, S.H. Verhelst, D. Kling, A. Chrusciel, J. Ruland, D. Krappmann, and K.P. Hopfner Structural analysis of phenothiazine derivatives as allosteric inhibitors of the MALT1 paracaspase Angew. Chem. Int. Ed. Engl. 52 2013 10384 10387
39. J. Staal, Y. Driege, T. Bekaert, A. Demeyer, D. Muyllaert, P. Van Damme, K. Gevaert, and R. Beyaert T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1 EMBO J. 30 2011 1742 1752
40. L. Sun, L. Deng, C.K. Ea, Z.P. Xia, and Z.J. Chen The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes Mol. Cell 14 2004 289 301
41. T. Uehata, H. Iwasaki, A. Vandenbon, K. Matsushita, E. Hernandez-Cuellar, K. Kuniyoshi, T. Satoh, T. Mino, Y. Suzuki, and D.M. Standley Malt1-induced cleavage of regnase-1 in CD4(+) helper T cells regulates immune activation Cell 153 2013 1036 1049
42. A.G. Uren, K. O'Rourke, L.A. Aravind, M.T. Pisabarro, S. Seshagiri, E.V. Koonin, and V.M. Dixit Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma Mol. Cell 6 2000 961 967
43. D. Wang, Y. You, S.M. Case, L.M. McAllister-Lucas, L. Wang, P.S. DiStefano, G. Nuñez, J. Bertin, and X. Lin A requirement for CARMA1 in TCR-induced NF-kappa B activation Nat. Immunol. 3 2002 830 835
44. E. Wegener, and D. Krappmann CARD-Bcl10-Malt1 signalosomes: missing link to NF-kappaB Sci. STKE 2007 2007 pe21
45. C. Wiesmann, L. Leder, J. Blank, A. Bernardi, S. Melkko, A. Decock, A. D'Arcy, F. Villard, P. Erbel, and N. Hughes Structural determinants of MALT1 protease activity J. Mol. Biol. 419 2012 4 21
46. M. Yan, J. Lee, S. Schilbach, A. Goddard, and V. Dixit mE10, a novel caspase recruitment domain-containing proapoptotic molecule J. Biol. Chem. 274 1999 10287 10292
47. J.W. Yu, P.D. Jeffrey, J.Y. Ha, X. Yang, and Y. Shi Crystal structure of the mucosa-associated lymphoid tissue lymphoma translocation 1 (MALT1) paracaspase region Proc. Natl. Acad. Sci. USA 108 2011 21004 21009
48. H. Zhou, I. Wertz, K. O'Rourke, M. Ultsch, S. Seshagiri, M. Eby, W. Xiao, and V.M. Dixit Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO Nature 427 2004 167 171