-
1
-
-
80355122714
-
V(D)J recombination: mechanisms of initiation
-
Schatz D.G., Swanson P.C. V(D)J recombination: mechanisms of initiation. Annu. Rev. Genet. 2011, 45:167-202.
-
(2011)
Annu. Rev. Genet.
, vol.45
, pp. 167-202
-
-
Schatz, D.G.1
Swanson, P.C.2
-
2
-
-
0034094425
-
The RAG proteins and V(D)J recombination: complexes, ends, and transposition
-
Fugmann S.D., Lee A.I., Shockett P.E., Villey I.J., Schatz D.G. The RAG proteins and V(D)J recombination: complexes, ends, and transposition. Annu. Rev. Immunol. 2000, 18:495-527.
-
(2000)
Annu. Rev. Immunol.
, vol.18
, pp. 495-527
-
-
Fugmann, S.D.1
Lee, A.I.2
Shockett, P.E.3
Villey, I.J.4
Schatz, D.G.5
-
3
-
-
0035997348
-
V(D)J recombination: RAG proteins, repair factors, and regulation
-
Gellert M. V(D)J recombination: RAG proteins, repair factors, and regulation. Annu. Rev. Biochem. 2002, 71:101-132.
-
(2002)
Annu. Rev. Biochem.
, vol.71
, pp. 101-132
-
-
Gellert, M.1
-
4
-
-
3242877122
-
Putting the pieces together: identification and characterization of structural domains in the V(D)J recombination protein RAG1
-
De P., Rodgers K.K. Putting the pieces together: identification and characterization of structural domains in the V(D)J recombination protein RAG1. Immunol. Rev. 2004, 200:70-82.
-
(2004)
Immunol. Rev.
, vol.200
, pp. 70-82
-
-
De, P.1
Rodgers, K.K.2
-
5
-
-
62049085849
-
A non-sequence-specific DNA binding mode of RAG1 is inhibited by RAG2
-
Zhao S., Gwyn L.M., De P., Rodgers K.K. A non-sequence-specific DNA binding mode of RAG1 is inhibited by RAG2. J. Mol. Biol. 2009, 387:744-758.
-
(2009)
J. Mol. Biol.
, vol.387
, pp. 744-758
-
-
Zhao, S.1
Gwyn, L.M.2
De, P.3
Rodgers, K.K.4
-
7
-
-
84875423827
-
The ATM protein kinase: regulating the cellular response to genotoxic stress, and more
-
Shiloh Y., Ziv Y. The ATM protein kinase: regulating the cellular response to genotoxic stress, and more. Nat. Rev. Mol. Cell Biol. 2013, 14:197-210.
-
(2013)
Nat. Rev. Mol. Cell Biol.
, vol.14
, pp. 197-210
-
-
Shiloh, Y.1
Ziv, Y.2
-
8
-
-
0037080679
-
Sensing of intermediates in V(D)J recombination by ATM
-
Perkins E.J., Nair A., Cowley D.O., Van Dyke T., Chang Y., Ramsden D.A. Sensing of intermediates in V(D)J recombination by ATM. Genes Dev. 2002, 16:159-164.
-
(2002)
Genes Dev.
, vol.16
, pp. 159-164
-
-
Perkins, E.J.1
Nair, A.2
Cowley, D.O.3
Van Dyke, T.4
Chang, Y.5
Ramsden, D.A.6
-
9
-
-
34250374139
-
Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes
-
Huang C.Y., Sharma G.G., Walker L.M., Bassing C.H., Pandita T.K., Sleckman B.P. Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes. J. Exp. Med. 2007, 204:1371-1381.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1371-1381
-
-
Huang, C.Y.1
Sharma, G.G.2
Walker, L.M.3
Bassing, C.H.4
Pandita, T.K.5
Sleckman, B.P.6
-
10
-
-
70849094673
-
Aberrantly resolved RAG-mediated DNA breaks in Atm-deficient lymphocytes target chromosomal breakpoints in cis
-
Mahowald G.K., Baron J.M., Mahowald M.A., Kulkarni S., Bredemeyer A.L., Bassing C.H., Sleckman B.P. Aberrantly resolved RAG-mediated DNA breaks in Atm-deficient lymphocytes target chromosomal breakpoints in cis. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:18339-18344.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 18339-18344
-
-
Mahowald, G.K.1
Baron, J.M.2
Mahowald, M.A.3
Kulkarni, S.4
Bredemeyer, A.L.5
Bassing, C.H.6
Sleckman, B.P.7
-
11
-
-
0042839614
-
Mechanism and regulation of human non-homologous DNA end-joining
-
Lieber M.R., Ma Y., Pannicke U., Schwarz K. Mechanism and regulation of human non-homologous DNA end-joining. Nat. Rev. Mol. Cell Biol. 2003, 4:712-720.
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 712-720
-
-
Lieber, M.R.1
Ma, Y.2
Pannicke, U.3
Schwarz, K.4
-
12
-
-
0037660900
-
The role of DNA breaks in genomic instability and tumorigenesis
-
Mills K.D., Ferguson D.O., Alt F.W. The role of DNA breaks in genomic instability and tumorigenesis. Immunol. Rev. 2003, 194:77-95.
-
(2003)
Immunol. Rev.
, vol.194
, pp. 77-95
-
-
Mills, K.D.1
Ferguson, D.O.2
Alt, F.W.3
-
13
-
-
0027769386
-
Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated
-
Schlissel M., Constantinescu A., Morrow T., Baxter M., Peng A. Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated. Genes Dev. 1993, 7:2520-2532.
-
(1993)
Genes Dev.
, vol.7
, pp. 2520-2532
-
-
Schlissel, M.1
Constantinescu, A.2
Morrow, T.3
Baxter, M.4
Peng, A.5
-
14
-
-
0033427205
-
Cyclin A/CDK2 regulates V(D)J recombination by coordinating RAG-2 accumulation and DNA repair
-
Lee J., Desiderio S. Cyclin A/CDK2 regulates V(D)J recombination by coordinating RAG-2 accumulation and DNA repair. Immunity 1999, 11:771-781.
-
(1999)
Immunity
, vol.11
, pp. 771-781
-
-
Lee, J.1
Desiderio, S.2
-
15
-
-
20444403003
-
Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle
-
Jiang H., Chang F.C., Ross A.E., Lee J., Nakayama K., Desiderio S. Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle. Mol. Cell 2005, 18:699-709.
-
(2005)
Mol. Cell
, vol.18
, pp. 699-709
-
-
Jiang, H.1
Chang, F.C.2
Ross, A.E.3
Lee, J.4
Nakayama, K.5
Desiderio, S.6
-
16
-
-
0036829568
-
RAG2 is down-regulated by cytoplasmic sequestration and ubiquitin-dependent degradation
-
Mizuta R., Mizuta M., Araki S., Kitamura D. RAG2 is down-regulated by cytoplasmic sequestration and ubiquitin-dependent degradation. J. Biol. Chem. 2002, 277:41423-41427.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 41423-41427
-
-
Mizuta, R.1
Mizuta, M.2
Araki, S.3
Kitamura, D.4
-
17
-
-
80053553994
-
The centrosome cycle: centriole biogenesis, duplication and inherent asymmetries
-
Nigg E.A., Stearns T. The centrosome cycle: centriole biogenesis, duplication and inherent asymmetries. Nat. Cell Biol. 2011, 13:1154-1160.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 1154-1160
-
-
Nigg, E.A.1
Stearns, T.2
-
18
-
-
67649842390
-
A zinc site in the C-terminal domain of RAG1 is essential for DNA cleavage activity
-
Gwyn L.M., Peak M.M., De P., Rahman N.S., Rodgers K.K. A zinc site in the C-terminal domain of RAG1 is essential for DNA cleavage activity. J. Mol. Biol. 2009, 390:863-878.
-
(2009)
J. Mol. Biol.
, vol.390
, pp. 863-878
-
-
Gwyn, L.M.1
Peak, M.M.2
De, P.3
Rahman, N.S.4
Rodgers, K.K.5
-
19
-
-
33747097562
-
ATM stabilizes DNA double-strand-break complexes during V(D)J recombination
-
Bredemeyer A.L., Sharma G.G., Huang C.Y., Helmink B.A., Walker L.M., Khor K.C., Nuskey B., Sullivan K.E., Pandita T.K., Bassing C.H., Sleckman B.P. ATM stabilizes DNA double-strand-break complexes during V(D)J recombination. Nature 2006, 442:466-470.
-
(2006)
Nature
, vol.442
, pp. 466-470
-
-
Bredemeyer, A.L.1
Sharma, G.G.2
Huang, C.Y.3
Helmink, B.A.4
Walker, L.M.5
Khor, K.C.6
Nuskey, B.7
Sullivan, K.E.8
Pandita, T.K.9
Bassing, C.H.10
Sleckman, B.P.11
-
20
-
-
0037232230
-
A small molecule Abl kinase inhibitor induces differentiation of Abelson virus-transformed pre-B cell lines
-
Muljo S.A., Schlissel M.S. A small molecule Abl kinase inhibitor induces differentiation of Abelson virus-transformed pre-B cell lines. Nat. Immunol. 2003, 4:31-37.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 31-37
-
-
Muljo, S.A.1
Schlissel, M.S.2
-
21
-
-
84867817084
-
A dual interaction between the DNA damage response protein MDC1 and the RAG1 subunit of the V(D)J recombinase
-
Coster G., Gold A., Chen D., Schatz D.G., Goldberg M. A dual interaction between the DNA damage response protein MDC1 and the RAG1 subunit of the V(D)J recombinase. J. Biol. Chem. 2012, 287:36488-36498.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 36488-36498
-
-
Coster, G.1
Gold, A.2
Chen, D.3
Schatz, D.G.4
Goldberg, M.5
-
22
-
-
0842343443
-
Visualization of antigen presentation by actin-mediated targeting of glycolipid-enriched membrane domains to the immune synapse of B cell APCs
-
Gordy C., Mishra S., Rodgers W. Visualization of antigen presentation by actin-mediated targeting of glycolipid-enriched membrane domains to the immune synapse of B cell APCs. J. Immunol. 2004, 172:2030-2038.
-
(2004)
J. Immunol.
, vol.172
, pp. 2030-2038
-
-
Gordy, C.1
Mishra, S.2
Rodgers, W.3
-
23
-
-
0042091962
-
Overlapping signals for protein degradation and nuclear localization define a role for intrinsic RAG-2 nuclear uptake in dividing cells
-
Ross A.E., Vuica M., Desiderio S. Overlapping signals for protein degradation and nuclear localization define a role for intrinsic RAG-2 nuclear uptake in dividing cells. Mol. Cell. Biol. 2003, 23:5308-5319.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 5308-5319
-
-
Ross, A.E.1
Vuica, M.2
Desiderio, S.3
-
24
-
-
0036315559
-
A short peptide at the C terminus is responsible for the nuclear localization of RAG2
-
Corneo B., Benmerah A., Villartay J.P. A short peptide at the C terminus is responsible for the nuclear localization of RAG2. Eur. J. Immunol. 2002, 32:2068-2073.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 2068-2073
-
-
Corneo, B.1
Benmerah, A.2
Villartay, J.P.3
-
25
-
-
84888377738
-
Peripheral subnuclear positioning suppresses Tcrb recombination and segregates Tcrb alleles from RAG2
-
Chan E.A., Teng G., Corbett E., Choudhury K.R., Bassing C.H., Schatz D.G., Krangel M.S. Peripheral subnuclear positioning suppresses Tcrb recombination and segregates Tcrb alleles from RAG2. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:E4628-E4637.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. E4628-E4637
-
-
Chan, E.A.1
Teng, G.2
Corbett, E.3
Choudhury, K.R.4
Bassing, C.H.5
Schatz, D.G.6
Krangel, M.S.7
-
26
-
-
38449101111
-
Interrelationship between alcohol, smoking, acetaldehyde and cancer
-
(Discussion 89-96, 198-199)
-
Salaspuro M. Interrelationship between alcohol, smoking, acetaldehyde and cancer. Novartis Found. Symp. 2007, 285:80-89. (Discussion 89-96, 198-199).
-
(2007)
Novartis Found. Symp.
, vol.285
, pp. 80-89
-
-
Salaspuro, M.1
-
27
-
-
78149464376
-
Formation of acetaldehyde-derived DNA adducts due to alcohol exposure
-
Yu H.S., Oyama T., Isse T., Kitagawa K., Pham T.T., Tanaka M., Kawamoto T. Formation of acetaldehyde-derived DNA adducts due to alcohol exposure. Chem. Biol. Interact. 2010, 188:367-375.
-
(2010)
Chem. Biol. Interact.
, vol.188
, pp. 367-375
-
-
Yu, H.S.1
Oyama, T.2
Isse, T.3
Kitagawa, K.4
Pham, T.T.5
Tanaka, M.6
Kawamoto, T.7
-
28
-
-
0032146749
-
Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1
-
Kudo N., Wolff B., Sekimoto T., Schreiner E.P., Yoneda Y., Yanagida M., Horinouchi S., Yoshida M. Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1. Exp. Cell Res. 1998, 242:540-547.
-
(1998)
Exp. Cell Res.
, vol.242
, pp. 540-547
-
-
Kudo, N.1
Wolff, B.2
Sekimoto, T.3
Schreiner, E.P.4
Yoneda, Y.5
Yanagida, M.6
Horinouchi, S.7
Yoshida, M.8
-
29
-
-
84874569364
-
The ataxia telangiectasia mutated kinase controls Igkappa allelic exclusion by inhibiting secondary Vkappa-to-Jkappa rearrangements
-
Steinel N.C., Lee B.S., Tubbs A.T., Bednarski J.J., Schulte E., Yang-Iott K.S., Schatz D.G., Sleckman B.P., Bassing C.H. The ataxia telangiectasia mutated kinase controls Igkappa allelic exclusion by inhibiting secondary Vkappa-to-Jkappa rearrangements. J. Exp. Med. 2013, 210:233-239.
-
(2013)
J. Exp. Med.
, vol.210
, pp. 233-239
-
-
Steinel, N.C.1
Lee, B.S.2
Tubbs, A.T.3
Bednarski, J.J.4
Schulte, E.5
Yang-Iott, K.S.6
Schatz, D.G.7
Sleckman, B.P.8
Bassing, C.H.9
-
30
-
-
1942538492
-
ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation
-
Stiff T., O'Driscoll M., Rief N., Iwabuchi K., Lobrich M., Jeggo P.A. ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Res. 2004, 64:2390-2396.
-
(2004)
Cancer Res.
, vol.64
, pp. 2390-2396
-
-
Stiff, T.1
O'Driscoll, M.2
Rief, N.3
Iwabuchi, K.4
Lobrich, M.5
Jeggo, P.A.6
-
31
-
-
37649026007
-
The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2
-
Ramon-Maiques S., Kuo A.J., Carney D., Matthews A.G., Oettinger M.A., Gozani O., Yang W. The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:18993-18998.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 18993-18998
-
-
Ramon-Maiques, S.1
Kuo, A.J.2
Carney, D.3
Matthews, A.G.4
Oettinger, M.A.5
Gozani, O.6
Yang, W.7
-
32
-
-
70149105262
-
Emerging connection between centrosome and DNA repair machinery
-
Shimada M., Komatsu K. Emerging connection between centrosome and DNA repair machinery. J. Radiat. Res. 2009, 50:295-301.
-
(2009)
J. Radiat. Res.
, vol.50
, pp. 295-301
-
-
Shimada, M.1
Komatsu, K.2
-
33
-
-
34247875990
-
Centrosomal localization of DNA damage checkpoint proteins
-
Zhang S., Hemmerich P., Grosse F. Centrosomal localization of DNA damage checkpoint proteins. J. Cell. Biochem. 2007, 101:451-465.
-
(2007)
J. Cell. Biochem.
, vol.101
, pp. 451-465
-
-
Zhang, S.1
Hemmerich, P.2
Grosse, F.3
-
34
-
-
84857735639
-
Characterization of BRCA1 protein targeting, dynamics, and function at the centrosome: a role for the nuclear export signal, CRM1, and Aurora A kinase
-
Brodie K.M., Henderson B.R. Characterization of BRCA1 protein targeting, dynamics, and function at the centrosome: a role for the nuclear export signal, CRM1, and Aurora A kinase. J. Biol. Chem. 2012, 287:7701-7716.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 7701-7716
-
-
Brodie, K.M.1
Henderson, B.R.2
-
35
-
-
35848964048
-
DNA damage-induced accumulation of centrosomal Chk1 contributes to its checkpoint function
-
Loffler H., Bochtler T., Fritz B., Tews B., Ho A.D., Lukas J., Bartek J., Kramer A. DNA damage-induced accumulation of centrosomal Chk1 contributes to its checkpoint function. Cell Cycle 2007, 6:2541-2548.
-
(2007)
Cell Cycle
, vol.6
, pp. 2541-2548
-
-
Loffler, H.1
Bochtler, T.2
Fritz, B.3
Tews, B.4
Ho, A.D.5
Lukas, J.6
Bartek, J.7
Kramer, A.8
-
36
-
-
84881397030
-
Centrosomal Che-1 protein is involved in the regulation of mitosis and DNA damage response by mediating pericentrin (PCNT)-dependent Chk1 protein localization
-
Sorino C., Bruno T., Desantis A., Di Certo M.G., Iezzi S., De Nicola F., Catena V., Floridi A., Chessa L., Passananti C., Cundari E., Fanciulli M. Centrosomal Che-1 protein is involved in the regulation of mitosis and DNA damage response by mediating pericentrin (PCNT)-dependent Chk1 protein localization. J. Biol. Chem. 2013, 288:23348-23357.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 23348-23357
-
-
Sorino, C.1
Bruno, T.2
Desantis, A.3
Di Certo, M.G.4
Iezzi, S.5
De Nicola, F.6
Catena, V.7
Floridi, A.8
Chessa, L.9
Passananti, C.10
Cundari, E.11
Fanciulli, M.12
|