Centrosomal Che-1 protein is involved in the regulation of mitosis and DNA damage response by mediating pericentrin (PCNT)-dependent Chk1 protein localization

Journal of Biological Chemistry

Volumn 288, Issue 32, 2013, Pages 23348-23357

  Sorino, Cristina ^a   Bruno, Tiziana ^a   Desantis, Agata ^a   Di Certo, Maria Grazia ^b   Iezzi, Simona ^a   De Nicola, Francesca ^a   Catena, Valeria ^c   Floridi, Aristide ^a   Chessa, Luciana ^d   Passananti, Claudio ^e   Cundari, Enrico ^d   Fanciulli, Maurizio ^a  

^a REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^c UNIVERSITY OF L'AQUILA   (Italy)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

^e SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DAMAGE RESPONSE; GENE TRANSCRIPTIONS; PROTEIN LOCALIZATION; RNA POLYMERASE; TUMOR CELLS;

CELL PROLIFERATION; NUCLEIC ACIDS; TRANSCRIPTION;

PROTEINS;

BINDING PROTEIN; CHECKPOINT KINASE 1; PERICENTRIN; PROTEIN CHE 1; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HCT116; CENTROSOME; CONTROLLED STUDY; DNA DAMAGE; FIBROBLAST; FLOW CYTOMETRY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INTERPHASE; MICROSCOPY; MITOSIS; MITOSIS SPINDLE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; WESTERN BLOTTING;

CENTROSOME; CHE-1; CHECKPOINT CONTROL; CHK1; DNA DAMAGE RESPONSE; MITOSIS; MITOTIC SPINDLE; PCNT;

ANTIGENS; APOPTOSIS REGULATORY PROTEINS; CDC2 PROTEIN KINASE; CELL LINE, TUMOR; CENTROSOME; CHROMOSOMES, HUMAN; CYCLIN B; DNA DAMAGE; G2 PHASE CELL CYCLE CHECKPOINTS; HUMANS; M PHASE CELL CYCLE CHECKPOINTS; MITOSIS; PROTEIN KINASES; REPRESSOR PROTEINS;

EID: 84881397030     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.465302     Document Type: Article

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