-
1
-
-
0031790311
-
The interferon-gamma gene as a positional and functional candidate gene for inflammatory bowel disease
-
Hampe J, Hermann B, Bridger S, MacPherson AJ, Mathew CG and Schreiber S. The interferon-gamma gene as a positional and functional candidate gene for inflammatory bowel disease. Int J Colorectal Dis 1998; 13: 260-263.
-
(1998)
Int J Colorectal Dis
, vol.13
, pp. 260-263
-
-
Hampe, J.1
Hermann, B.2
Bridger, S.3
MacPherson, A.J.4
Mathew, C.G.5
Schreiber, S.6
-
2
-
-
0032199845
-
Genome-wide scanning in inflammatory bowel diseases
-
Hugot JP and Thomas G. Genome-wide scanning in inflammatory bowel diseases. Dig Dis 1998; 16: 364-369.
-
(1998)
Dig Dis
, vol.16
, pp. 364-369
-
-
Hugot, J.P.1
Thomas, G.2
-
3
-
-
2442674327
-
Genome scan analyses and positional cloning strategy in IBD: successTablees and limitations
-
Wild GE and Rioux JD. Genome scan analyses and positional cloning strategy in IBD: successTablees and limitations. Best Pract Res Clin Gastroenterol 2004; 18: 541-553.
-
(2004)
Best Pract Res Clin Gastroenterol
, vol.18
, pp. 541-553
-
-
Wild, G.E.1
Rioux, J.D.2
-
4
-
-
70949107842
-
Inflammatory bowel disease
-
Abraham C and Cho JH. Inflammatory bowel disease. N Engl J Med 2009; 361: 2066-2078.
-
(2009)
N Engl J Med
, vol.361
, pp. 2066-2078
-
-
Abraham, C.1
Cho, J.H.2
-
5
-
-
79955566359
-
Recent insights into the genetics of inflammatory bowel disease
-
Cho JH and Brant SR. Recent insights into the genetics of inflammatory bowel disease. Gastroenterology 2011; 140: 1704-1712.
-
(2011)
Gastroenterology
, vol.140
, pp. 1704-1712
-
-
Cho, J.H.1
Brant, S.R.2
-
6
-
-
79955064497
-
Treatment with IL-27 attenuates experimental colitis through the suppression of the development of IL-17-producing T helper cells
-
Sasaoka T, Ito M, Yamashita J, Nakajima K, Tanaka I, Narita M, Hara Y, Hada K, Takahashi M, Ohno Y, Matsuo T, Kaneshiro Y, Tanaka H and Kaneko K. Treatment with IL-27 attenuates experimental colitis through the suppression of the development of IL-17-producing T helper cells. Am J Physiol Gastrointest Liver Physiol 2011; 300: G568-G576.
-
(2011)
Am J Physiol Gastrointest Liver Physiol
, vol.300
, pp. G568-G576
-
-
Sasaoka, T.1
Ito, M.2
Yamashita, J.3
Nakajima, K.4
Tanaka, I.5
Narita, M.6
Hara, Y.7
Hada, K.8
Takahashi, M.9
Ohno, Y.10
Matsuo, T.11
Kaneshiro, Y.12
Tanaka, H.13
Kaneko, K.14
-
7
-
-
27944495565
-
T helper 1-inducing property of IL-27/WSX-1 signaling is required for the induction of experimental colitis
-
Honda K, Nakamura K, Matsui N, Takahashi M, Kitamura Y, Mizutani T, Harada N, Nawata H, Hamano S and Yoshida H. T helper 1-inducing property of IL-27/WSX-1 signaling is required for the induction of experimental colitis. Inflamm Bowel Dis 2005; 11: 1044-1052.
-
(2005)
Inflamm Bowel Dis
, vol.11
, pp. 1044-1052
-
-
Honda, K.1
Nakamura, K.2
Matsui, N.3
Takahashi, M.4
Kitamura, Y.5
Mizutani, T.6
Harada, N.7
Nawata, H.8
Hamano, S.9
Yoshida, H.10
-
8
-
-
70349659805
-
Interleukin-27 polymorphisms are associated with inflammatory bowel diseases in a Korean population
-
Li CS, Zhang Q, Lee KJ, Cho SW, Lee KM, Hahm KB, Choi SC, Yun KJ, Chung HT and Chae SC. Interleukin-27 polymorphisms are associated with inflammatory bowel diseases in a Korean population. J Gastroenterol Hepatol 2009; 24: 1692-1696.
-
(2009)
J Gastroenterol Hepatol
, vol.24
, pp. 1692-1696
-
-
Li, C.S.1
Zhang, Q.2
Lee, K.J.3
Cho, S.W.4
Lee, K.M.5
Hahm, K.B.6
Choi, S.C.7
Yun, K.J.8
Chung, H.T.9
Chae, S.C.10
-
9
-
-
0033531235
-
Multiplex PCR/LDR for detection of K-ras mutations in primary colon tumors
-
Khanna M, Park P, Zirvi M, Cao W, Picon A, Day J, Paty P and Barany F. Multiplex PCR/LDR for detection of K-ras mutations in primary colon tumors. Oncogene 1999; 18: 27-38.
-
(1999)
Oncogene
, vol.18
, pp. 27-38
-
-
Khanna, M.1
Park, P.2
Zirvi, M.3
Cao, W.4
Picon, A.5
Day, J.6
Paty, P.7
Barany, F.8
-
10
-
-
0142156650
-
Modeling and E-M estimation of haplotype-specific relative risks from genotype data for a case-control study of unrelated individuals
-
Stram DO, Leigh Pearce C, Bretsky P, Freedman M, Hirschhorn JN, Altshuler D, Kolonel LN, Henderson BE and Thomas DC. Modeling and E-M estimation of haplotype-specific relative risks from genotype data for a case-control study of unrelated individuals. Hum Hered 2003; 55: 179-190.
-
(2003)
Hum Hered
, vol.55
, pp. 179-190
-
-
Stram, D.O.1
Leigh Pearce, C.2
Bretsky, P.3
Freedman, M.4
Hirschhorn, J.N.5
Altshuler, D.6
Kolonel, L.N.7
Henderson, B.E.8
Thomas, D.C.9
-
11
-
-
0038326688
-
Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment
-
Takeda A, Hamano S, Yamanaka A, Hanada T, Ishibashi T, Mak TW, Yoshimura A and Yoshida H. Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment. J Immunol 2003; 170: 4886-4890.
-
(2003)
J Immunol
, vol.170
, pp. 4886-4890
-
-
Takeda, A.1
Hamano, S.2
Yamanaka, A.3
Hanada, T.4
Ishibashi, T.5
Mak, T.W.6
Yoshimura, A.7
Yoshida, H.8
-
12
-
-
0141519112
-
IL-27 and IFN-alpha signal via Stat1 and Stat3 and induce T-Bet and IL-12Rbeta2 in naive T cells
-
Hibbert L, Pflanz S, De Waal Malefyt R and Kastelein RA. IL-27 and IFN-alpha signal via Stat1 and Stat3 and induce T-Bet and IL-12Rbeta2 in naive T cells. J Interferon Cytokine Res 2003; 23: 513-522.
-
(2003)
J Interferon Cytokine Res
, vol.23
, pp. 513-522
-
-
Hibbert, L.1
Pflanz, S.2
De Waal Malefyt, R.3
Kastelein, R.A.4
-
13
-
-
0345570521
-
The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection
-
Villarino A, Hibbert L, Lieberman L, Wilson E, Mak T, Yoshida H, Kastelein RA, Saris C and Hunter CA. The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection. Immunity 2003; 19: 645-655.
-
(2003)
Immunity
, vol.19
, pp. 645-655
-
-
Villarino, A.1
Hibbert, L.2
Lieberman, L.3
Wilson, E.4
Mak, T.5
Yoshida, H.6
Kastelein, R.A.7
Saris, C.8
Hunter, C.A.9
-
14
-
-
4644225089
-
An indispensable role for STAT1 in IL-27-induced T-bet expression but not proliferation of naive CD4+ T cells
-
Kamiya S, Owaki T, Morishima N, Fukai F, Mizuguchi J and Yoshimoto T. An indispensable role for STAT1 in IL-27-induced T-bet expression but not proliferation of naive CD4+ T cells. J Immunol 2004; 173: 3871-3877.
-
(2004)
J Immunol
, vol.173
, pp. 3871-3877
-
-
Kamiya, S.1
Owaki, T.2
Morishima, N.3
Fukai, F.4
Mizuguchi, J.5
Yoshimoto, T.6
-
15
-
-
18444385868
-
IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells
-
Pflanz S, Timans JC, Cheung J, Rosales R, Kanzler H, Gilbert J, Hibbert L, Churakova T, Travis M, Vaisberg E, Blumenschein WM, Mattson JD, Wagner JL, To W, Zurawski S, McClanahan TK, Gorman DM, Bazan JF, de Waal Malefyt R, Rennick D and Kastelein RA. IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells. Immunity 2002; 16: 779-790.
-
(2002)
Immunity
, vol.16
, pp. 779-790
-
-
Pflanz, S.1
Timans, J.C.2
Cheung, J.3
Rosales, R.4
Kanzler, H.5
Gilbert, J.6
Hibbert, L.7
Churakova, T.8
Travis, M.9
Vaisberg, E.10
Blumenschein, W.M.11
Mattson, J.D.12
Wagner, J.L.13
To, W.14
Zurawski, S.15
McClanahan, T.K.16
Gorman, D.M.17
Bazan, J.F.18
de Waal Malefyt, R.19
Rennick, D.20
Kastelein, R.A.21
more..
-
16
-
-
33751568890
-
IL-27 induces Th1 differentiation via p38 MAPK/T-bet- and intercellular adhesion molecule-1/LFA-1/ERK1/2-dependent pathways
-
Owaki T, Asakawa M, Fukai F, Mizuguchi J and Yoshimoto T. IL-27 induces Th1 differentiation via p38 MAPK/T-bet- and intercellular adhesion molecule-1/LFA-1/ERK1/2-dependent pathways. J Immunol 2006; 177: 7579-7587.
-
(2006)
J Immunol
, vol.177
, pp. 7579-7587
-
-
Owaki, T.1
Asakawa, M.2
Fukai, F.3
Mizuguchi, J.4
Yoshimoto, T.5
-
17
-
-
77955302693
-
Interleukin-27 induces a STAT1/3-and NF-kappaB-dependent proinflammatory cytokine profile in human monocytes
-
Guzzo C, Che Mat NF and Gee K. Interleukin-27 induces a STAT1/3-and NF-kappaB-dependent proinflammatory cytokine profile in human monocytes. J Biol Chem 2010; 285: 24404-24411.
-
(2010)
J Biol Chem
, vol.285
, pp. 24404-24411
-
-
Guzzo, C.1
Che Mat, N.F.2
Gee, K.3
-
18
-
-
33644536099
-
IL-27 suppresses CD28-mediated IL-2 production through suppressor of cytokine signaling 3
-
Owaki T, Asakawa M, Kamiya S, Takeda K, Fukai F, Mizuguchi J and Yoshimoto T. IL-27 suppresses CD28-mediated IL-2 production through suppressor of cytokine signaling 3. J Immunol 2006; 176: 2773-2780.
-
(2006)
J Immunol
, vol.176
, pp. 2773-2780
-
-
Owaki, T.1
Asakawa, M.2
Kamiya, S.3
Takeda, K.4
Fukai, F.5
Mizuguchi, J.6
Yoshimoto, T.7
-
19
-
-
33846419491
-
Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals
-
Villarino AV, Tato CM, Stumhofer JS, Yao Z, Cui YK, Hennighausen L, O'Shea JJ and Hunter CA. Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals. J Exp Med 2007; 204: 65-71.
-
(2007)
J Exp Med
, vol.204
, pp. 65-71
-
-
Villarino, A.V.1
Tato, C.M.2
Stumhofer, J.S.3
Yao, Z.4
Cui, Y.K.5
Hennighausen, L.6
O'Shea, J.J.7
Hunter, C.A.8
-
20
-
-
33749515631
-
Two-sided roles of IL-27: induction of Th1 differentiation on naive CD4+ T cells versus suppression of proinflammatory cytokine production including IL-23-induced IL-17 on activated CD4+ T cells partially through STAT3-dependent mechanism
-
Yoshimura T, Takeda A, Hamano S, Miyazaki Y, Kinjyo I, Ishibashi T, Yoshimura A and Yoshida H. Two-sided roles of IL-27: induction of Th1 differentiation on naive CD4+ T cells versus suppression of proinflammatory cytokine production including IL-23-induced IL-17 on activated CD4+ T cells partially through STAT3-dependent mechanism. J Immunol 2006; 177: 5377-5385.
-
(2006)
J Immunol
, vol.177
, pp. 5377-5385
-
-
Yoshimura, T.1
Takeda, A.2
Hamano, S.3
Miyazaki, Y.4
Kinjyo, I.5
Ishibashi, T.6
Yoshimura, A.7
Yoshida, H.8
-
21
-
-
36248970701
-
A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells
-
Awasthi A, Carrier Y, Peron JP, Bettelli E, Kamanaka M, Flavell RA, Kuchroo VK, Oukka M and Weiner HL. A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells. Nat Immunol 2007; 8: 1380-1389.
-
(2007)
Nat Immunol
, vol.8
, pp. 1380-1389
-
-
Awasthi, A.1
Carrier, Y.2
Peron, J.P.3
Bettelli, E.4
Kamanaka, M.5
Flavell, R.A.6
Kuchroo, V.K.7
Oukka, M.8
Weiner, H.L.9
-
22
-
-
36248970702
-
Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells
-
Fitzgerald DC, Zhang GX, El-Behi M, Fonseca-Kelly Z, Li H, Yu S, Saris CJ, Gran B, Ciric B and Rostami A. Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells. Nat Immunol 2007; 8: 1372-1379.
-
(2007)
Nat Immunol
, vol.8
, pp. 1372-1379
-
-
Fitzgerald, D.C.1
Zhang, G.X.2
El-Behi, M.3
Fonseca-Kelly, Z.4
Li, H.5
Yu, S.6
Saris, C.J.7
Gran, B.8
Ciric, B.9
Rostami, A.10
-
23
-
-
33747593830
-
Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system
-
Stumhofer JS, Laurence A, Wilson EH, Huang E, Tato CM, Johnson LM, Villarino AV, Huang Q, Yoshimura A, Sehy D, Saris CJ, O'Shea JJ, Hennighausen L, Ernst M and Hunter CA. Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system. Nat Immunol 2006; 7: 937-945.
-
(2006)
Nat Immunol
, vol.7
, pp. 937-945
-
-
Stumhofer, J.S.1
Laurence, A.2
Wilson, E.H.3
Huang, E.4
Tato, C.M.5
Johnson, L.M.6
Villarino, A.V.7
Huang, Q.8
Yoshimura, A.9
Sehy, D.10
Saris, C.J.11
O'Shea, J.J.12
Hennighausen, L.13
Ernst, M.14
Hunter, C.A.15
-
24
-
-
36248951161
-
Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10
-
Stumhofer JS, Silver JS, Laurence A, Porrett PM, Harris TH, Turka LA, Ernst M, Saris CJ, O'Shea JJ and Hunter CA. Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10. Nat Immunol 2007; 8: 1363-1371.
-
(2007)
Nat Immunol
, vol.8
, pp. 1363-1371
-
-
Stumhofer, J.S.1
Silver, J.S.2
Laurence, A.3
Porrett, P.M.4
Harris, T.H.5
Turka, L.A.6
Ernst, M.7
Saris, C.J.8
O'Shea, J.J.9
Hunter, C.A.10
-
25
-
-
33947626493
-
Identification of polymorphisms in human interleukin-27 and their association with asthma in a Korean population
-
Chae SC, Li CS, Kim KM, Yang JY, Zhang Q, Lee YC, Yang YS and Chung HT. Identification of polymorphisms in human interleukin-27 and their association with asthma in a Korean population. J Hum Genet 2007; 52: 355-361.
-
(2007)
J Hum Genet
, vol.52
, pp. 355-361
-
-
Chae, S.C.1
Li, C.S.2
Kim, K.M.3
Yang, J.Y.4
Zhang, Q.5
Lee, Y.C.6
Yang, Y.S.7
Chung, H.T.8
-
26
-
-
50849129534
-
Association of interleukin (IL)-12 and IL-27 gene polymorphisms with chronic obstructive pulmonary disease in a Chinese population
-
Huang N, Liu L, Wang XZ, Liu D, Yin SY and Yang XD. Association of interleukin (IL)-12 and IL-27 gene polymorphisms with chronic obstructive pulmonary disease in a Chinese population. DNA Cell Biol 2008; 27: 527-531.
-
(2008)
DNA Cell Biol
, vol.27
, pp. 527-531
-
-
Huang, N.1
Liu, L.2
Wang, X.Z.3
Liu, D.4
Yin, S.Y.5
Yang, X.D.6
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