Inactivation of multiple bacterial histidine kinases by targeting the ATP-binding domain

ACS Chemical Biology

Volumn 10, Issue 1, 2015, Pages 328-335

  Wilke, Kaelyn E ^a   Francis, Samson ^a   Carlson, Erin E ^a  

^a INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMPICILLIN; ANTIBIOTIC AGENT; BACTERIAL ENZYME; BACTERIAL HISTIDINE KINASE; CHLORAMPHENICOL; DIMETHYL SULFOXIDE; PENICILLIN DERIVATIVE; PROTEIN HISTIDINE KINASE; UNCLASSIFIED DRUG; VANCOMYCIN; ANTIINFECTIVE AGENT; MOLECULAR LIBRARY; PROTEIN BINDING; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; PROTEIN-HISTIDINE KINASE;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; ASSAY; BACTERIA; CATALYSIS; CONTROLLED STUDY; FLUORESCENCE; HIGH THROUGHPUT SCREENING; HUMAN; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; ANIMAL; BACILLUS SUBTILIS; CELL SURVIVAL; CHEMISTRY; CHLOROCEBUS AETHIOPS; DOSE RESPONSE; DRUG DEVELOPMENT; DRUG EFFECTS; ENZYME ACTIVE SITE; ENZYMOLOGY; ESCHERICHIA COLI; FLUORESCENCE POLARIZATION; METABOLISM; MOLECULAR LIBRARY; PHARMACOLOGY; VERO CELL LINE;

BACTERIA (MICROORGANISMS);

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; CATALYTIC DOMAIN; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DISCOVERY; ESCHERICHIA COLI; FLUORESCENCE POLARIZATION; HIGH-THROUGHPUT SCREENING ASSAYS; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; SMALL MOLECULE LIBRARIES; VERO CELLS;

EID: 84921395960     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb5008019     Document Type: Article

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