Paclitaxel-loaded micelles enhance transvascular permeability and retention of nanomedicines in tumors

International Journal of Pharmaceutics

Volumn 479, Issue 2, 2015, Pages 399-407

  Danhier, Fabienne ^a   Danhier, Pierre ^a   De Saedeleer, Christophe J ^a   Fruytier, Anne Catherine ^a   Schleich, Nathalie ^a   Rieux, Anne Des ^a   Sonveaux, Pierre ^a   Gallez, Bernard ^a   Préat, Véronique ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

EPR effect; Nanomedicine; Paclitaxel; Polymeric micelles; Tumor targeting; Tumor vasculature

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COPOLYMER; DOXORUBICIN; IRON OXIDE; LIPOSOME; NANOPARTICLE; PACLITAXEL; ANTINEOPLASTIC AGENT; MICELLE; POLYMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CANCER INHIBITION; CHEMICAL COMPOSITION; COLON CARCINOMA; CONTROLLED STUDY; DRUG EFFICACY; DRUG PENETRATION; DRUG RETENTION; DRUG SOLUBILITY; ELECTRON SPIN RESONANCE; ENDOTHELIUM CELL; ENHANCED PERMEABILITY AND RETENTION; FEMALE; IMMUNOFLUORESCENCE; LIVER CELL CARCINOMA; MACROMOLECULE; MICELLE; MOUSE; NANOMEDICINE; NONHUMAN; PERICYTE; POLYMERIC MICELLE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; TUMOR MICROENVIRONMENT; TUMOR VASCULARIZATION; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; DRUG EFFECTS; MALE; NEOPLASMS; PATHOLOGY; PERMEABILITY; TIME;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; FEMALE; LIPOSOMES; MALE; MICE; MICE, INBRED BALB C; MICELLES; NANOMEDICINE; NANOPARTICLES; NEOPLASMS; PACLITAXEL; PERMEABILITY; POLYMERS; TIME FACTORS; TUMOR MICROENVIRONMENT;

EID: 84921341089     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.01.009     Document Type: Article

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