-
1
-
-
14944385553
-
Global cancer statistics, 2002
-
Parkin DM, Bray F, Ferlay J and Pisani P. Global cancer statistics, 2002. CA Cancer J Clin. 2005; 55(2):74-108.
-
(2005)
CA Cancer J Clin.
, vol.55
, Issue.2
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
2
-
-
0347503603
-
Palliative therapy of disseminated malignant melanoma: a systematic review of 41 randomised clinical trials
-
Eigentler TK, Caroli UM, Radny P and Garbe C. Palliative therapy of disseminated malignant melanoma: a systematic review of 41 randomised clinical trials. Lancet Oncol. 2003; 4(12):748-759.
-
(2003)
Lancet Oncol.
, vol.4
, Issue.12
, pp. 748-759
-
-
Eigentler, T.K.1
Caroli, U.M.2
Radny, P.3
Garbe, C.4
-
3
-
-
0033989205
-
Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma
-
Middleton MR, Grob JJ, Aaronson N, Fierlbeck G, Tilgen W, Seiter S, Gore M, Aamdal S, Cebon J, Coates A, Dreno B, Henz M, Schadendorf D, Kapp A, Weiss J, Fraass U, et al. Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma. J Clin Oncol. 2000; 18(1):158-166.
-
(2000)
J Clin Oncol.
, vol.18
, Issue.1
, pp. 158-166
-
-
Middleton, M.R.1
Grob, J.J.2
Aaronson, N.3
Fierlbeck, G.4
Tilgen, W.5
Seiter, S.6
Gore, M.7
Aamdal, S.8
Cebon, J.9
Coates, A.10
Dreno, B.11
Henz, M.12
Schadendorf, D.13
Kapp, A.14
Weiss, J.15
Fraass, U.16
-
4
-
-
0032784651
-
Metabolic activation of dacarbazine by human cytochromes P450: the role of CYP1A1, CYP1A2, and CYP2E1
-
Reid JM, Kuffel MJ, Miller JK, Rios R and Ames MM. Metabolic activation of dacarbazine by human cytochromes P450: the role of CYP1A1, CYP1A2, and CYP2E1. Clin Cancer Res. 1999; 5(8):2192-2197.
-
(1999)
Clin Cancer Res.
, vol.5
, Issue.8
, pp. 2192-2197
-
-
Reid, J.M.1
Kuffel, M.J.2
Miller, J.K.3
Rios, R.4
Ames, M.M.5
-
5
-
-
0030993717
-
Temozolomide: a review of its discovery, chemical properties, pre-clinical development and clinical trials
-
Newlands ES, Stevens MF, Wedge SR, Wheelhouse RT and Brock C. Temozolomide: a review of its discovery, chemical properties, pre-clinical development and clinical trials. Cancer Treat Rev. 1997; 23(1):35-61.
-
(1997)
Cancer Treat Rev.
, vol.23
, Issue.1
, pp. 35-61
-
-
Newlands, E.S.1
Stevens, M.F.2
Wedge, S.R.3
Wheelhouse, R.T.4
Brock, C.5
-
6
-
-
84856233300
-
Balancing repair and tolerance of DNA damage caused by alkylating agents
-
Fu D, Calvo JA and Samson LD. Balancing repair and tolerance of DNA damage caused by alkylating agents. Nat Rev Cancer. 2012; 12(2):104-120.
-
(2012)
Nat Rev Cancer.
, vol.12
, Issue.2
, pp. 104-120
-
-
Fu, D.1
Calvo, J.A.2
Samson, L.D.3
-
7
-
-
58749097764
-
Temozolomideand fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53
-
Naumann SC, Roos WP, Jost E, Belohlavek C, Lennerz V, Schmidt CW, Christmann M and Kaina B. Temozolomideand fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53. Br J Cancer. 2009; 100(2):322-333.
-
(2009)
Br J Cancer.
, vol.100
, Issue.2
, pp. 322-333
-
-
Naumann, S.C.1
Roos, W.P.2
Jost, E.3
Belohlavek, C.4
Lennerz, V.5
Schmidt, C.W.6
Christmann, M.7
Kaina, B.8
-
8
-
-
35648934994
-
Temozolomide induces senescence but not apoptosis in human melanoma cells
-
Mhaidat NM, Zhang XD, Allen J, Avery-Kiejda KA, Scott RJ and Hersey P. Temozolomide induces senescence but not apoptosis in human melanoma cells. Br J Cancer. 2007; 97(9):1225-1233.
-
(2007)
Br J Cancer.
, vol.97
, Issue.9
, pp. 1225-1233
-
-
Mhaidat, N.M.1
Zhang, X.D.2
Allen, J.3
Avery-Kiejda, K.A.4
Scott, R.J.5
Hersey, P.6
-
9
-
-
84873830422
-
Survival and death strategies in glioma cells: autophagy, senescence and apoptosis triggered by a single type of temozolomideinduced DNA damage
-
Knizhnik AV, Roos WP, Nikolova T, Quiros S, Tomaszowski KH, Christmann M and Kaina B. Survival and death strategies in glioma cells: autophagy, senescence and apoptosis triggered by a single type of temozolomideinduced DNA damage. PLoS One. 2013; 8(1):e55665.
-
(2013)
PLoS One.
, vol.8
, Issue.1
-
-
Knizhnik, A.V.1
Roos, W.P.2
Nikolova, T.3
Quiros, S.4
Tomaszowski, K.H.5
Christmann, M.6
Kaina, B.7
-
10
-
-
0019957212
-
Formation of the cross-link 1-[N3-deoxycytidyl),2-[N1-deoxyguanosinyl] ethane in DNA treated with N,N'-bis(2-chloroethyl)-Nnitrosourea
-
Tong WP, Kirk MC and Ludlum DB. Formation of the cross-link 1-[N3-deoxycytidyl),2-[N1-deoxyguanosinyl] ethane in DNA treated with N,N'-bis(2-chloroethyl)-Nnitrosourea. Cancer Res. 1982; 42(8):3102-3105.
-
(1982)
Cancer Res.
, vol.42
, Issue.8
, pp. 3102-3105
-
-
Tong, W.P.1
Kirk, M.C.2
Ludlum, D.B.3
-
11
-
-
1842562211
-
Fotemustine compared with dacarbazine in patients with disseminated malignant melanoma: a phase III study
-
Avril MF, Aamdal S, Grob JJ, Hauschild A, Mohr P, Bonerandi JJ, Weichenthal M, Neuber K, Bieber T, Gilde K, Guillem Porta V, Fra J, Bonneterre J, Saiag P, Kamanabrou D, Pehamberger H, et al. Fotemustine compared with dacarbazine in patients with disseminated malignant melanoma: a phase III study. J Clin Oncol. 2004; 22(6):1118-1125.
-
(2004)
J Clin Oncol.
, vol.22
, Issue.6
, pp. 1118-1125
-
-
Avril, M.F.1
Aamdal, S.2
Grob, J.J.3
Hauschild, A.4
Mohr, P.5
Bonerandi, J.J.6
Weichenthal, M.7
Neuber, K.8
Bieber, T.9
Gilde, K.10
Guillem Porta, V.11
Fra, J.12
Bonneterre, J.13
Saiag, P.14
Kamanabrou, D.15
Pehamberger, H.16
-
12
-
-
0028113292
-
Phase II trial of fotemustine in patients with metastatic malignant melanoma
-
Falkson CI, Falkson G and Falkson HC. Phase II trial of fotemustine in patients with metastatic malignant melanoma. Invest New Drugs. 1994; 12(3):251-254.
-
(1994)
Invest New Drugs.
, vol.12
, Issue.3
, pp. 251-254
-
-
Falkson, C.I.1
Falkson, G.2
Falkson, H.C.3
-
13
-
-
84882969783
-
Chemotherapy in the management of brain metastases: the emerging role of fotemustine for patients with melanoma and NSCLC
-
Addeo R, Zappavigna S, Luce A, Facchini S and Caraglia M. Chemotherapy in the management of brain metastases: the emerging role of fotemustine for patients with melanoma and NSCLC. Expert opinion on drug safety. 2013; 12(5):729-740.
-
(2013)
Expert opinion on drug safety.
, vol.12
, Issue.5
, pp. 729-740
-
-
Addeo, R.1
Zappavigna, S.2
Luce, A.3
Facchini, S.4
Caraglia, M.5
-
14
-
-
34447314728
-
MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents
-
Kaina B, Christmann M, Naumann S and Roos WP. MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents. DNA Repair (Amst). 2007; 6(8):1079-1099.
-
(2007)
DNA Repair (Amst).
, vol.6
, Issue.8
, pp. 1079-1099
-
-
Kaina, B.1
Christmann, M.2
Naumann, S.3
Roos, W.P.4
-
15
-
-
0025941670
-
Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents
-
Kaina B, Fritz G, Mitra S and Coquerelle T. Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents. Carcinogenesis. 1991; 12(10):1857-1867.
-
(1991)
Carcinogenesis.
, vol.12
, Issue.10
, pp. 1857-1867
-
-
Kaina, B.1
Fritz, G.2
Mitra, S.3
Coquerelle, T.4
-
16
-
-
0026612039
-
O6-methylguanine-DNA methyltransferase activity in human tumors
-
Chen JM, Zhang YP, Wang C, Sun Y, Fujimoto J and Ikenaga M. O6-methylguanine-DNA methyltransferase activity in human tumors. Carcinogenesis. 1992; 13(9):1503-1507.
-
(1992)
Carcinogenesis.
, vol.13
, Issue.9
, pp. 1503-1507
-
-
Chen, J.M.1
Zhang, Y.P.2
Wang, C.3
Sun, Y.4
Fujimoto, J.5
Ikenaga, M.6
-
17
-
-
79960656490
-
O(6)- Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: enzyme activity, promoter methylation and immunohistochemistry
-
Christmann M, Verbeek B, Roos WP and Kaina B. O(6)- Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: enzyme activity, promoter methylation and immunohistochemistry. Biochim Biophys Acta. 2011; 1816(2):179-190.
-
(2011)
Biochim Biophys Acta.
, vol.1816
, Issue.2
, pp. 179-190
-
-
Christmann, M.1
Verbeek, B.2
Roos, W.P.3
Kaina, B.4
-
18
-
-
0031597371
-
O6-methylguanine-DNA methyltransferase in pretreatment tumour biopsies as a predictor of response to temozolomide in melanoma
-
Middleton MR, Lunn JM, Morris C, Rustin G, Wedge SR, Brampton MH, Lind MJ, Lee SM, Newell DR, Bleehen NM, Newlands ES, Calvert AH, Margison GP and Thatcher N. O6-methylguanine-DNA methyltransferase in pretreatment tumour biopsies as a predictor of response to temozolomide in melanoma. Br J Cancer. 1998; 78(9):1199- 1202.
-
(1998)
Br J Cancer.
, vol.78
, Issue.9
, pp. 1199- 1202
-
-
Middleton, M.R.1
Lunn, J.M.2
Morris, C.3
Rustin, G.4
Wedge, S.R.5
Brampton, M.H.6
Lind, M.J.7
Lee, S.M.8
Newell, D.R.9
Bleehen, N.M.10
Newlands, E.S.11
Calvert, A.H.12
Margison, G.P.13
Thatcher, N.14
-
19
-
-
79958803363
-
Intrinsic Anticancer Drug Resistance of Malignant Melanoma Cells Is Abrogated by IFN-{beta} and Valproic Acid
-
Roos WP, Jost E, Belohlavek C, Nagel G, Fritz G and Kaina B. Intrinsic Anticancer Drug Resistance of Malignant Melanoma Cells Is Abrogated by IFN-{beta} and Valproic Acid. Cancer Res. 2011; 71(12):4150-4160.
-
(2011)
Cancer Res.
, vol.71
, Issue.12
, pp. 4150-4160
-
-
Roos, W.P.1
Jost, E.2
Belohlavek, C.3
Nagel, G.4
Fritz, G.5
Kaina, B.6
-
20
-
-
0035843169
-
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
-
Soengas MS, Capodieci P, Polsky D, Mora J, Esteller M, Opitz-Araya X, McCombie R, Herman JG, Gerald WL, Lazebnik YA, Cordon-Cardo C and Lowe SW. Inactivation of the apoptosis effector Apaf-1 in malignant melanoma. Nature. 2001; 409(6817):207-211.
-
(2001)
Nature.
, vol.409
, Issue.6817
, pp. 207-211
-
-
Soengas, M.S.1
Capodieci, P.2
Polsky, D.3
Mora, J.4
Esteller, M.5
Opitz-Araya, X.6
McCombie, R.7
Herman, J.G.8
Gerald, W.L.9
Lazebnik, Y.A.10
Cordon-Cardo, C.11
Lowe, S.W.12
-
21
-
-
84899428083
-
Malignant melanoma cells acquire resistance to DNA interstrand cross-linking chemotherapeutics by p53- triggered upregulation of DDB2/XPC-mediated DNA repair
-
Barckhausen C, Roos WP, Naumann SC and Kaina B. Malignant melanoma cells acquire resistance to DNA interstrand cross-linking chemotherapeutics by p53- triggered upregulation of DDB2/XPC-mediated DNA repair. Oncogene. 2014; 33(15):1964-1974.
-
(2014)
Oncogene.
, vol.33
, Issue.15
, pp. 1964-1974
-
-
Barckhausen, C.1
Roos, W.P.2
Naumann, S.C.3
Kaina, B.4
-
22
-
-
0035313980
-
Acquired resistance of melanoma cells to the antineoplastic agent fotemustine is caused by reactivation of the DNA repair gene MGMT
-
Christmann M, Pick M, Lage H, Schadendorf D and Kaina B. Acquired resistance of melanoma cells to the antineoplastic agent fotemustine is caused by reactivation of the DNA repair gene MGMT. Int J Cancer. 2001; 92(1):123-129.
-
(2001)
Int J Cancer.
, vol.92
, Issue.1
, pp. 123-129
-
-
Christmann, M.1
Pick, M.2
Lage, H.3
Schadendorf, D.4
Kaina, B.5
-
23
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, Teague J, Woffendin H, Garnett MJ, Bottomley W, Davis N, Dicks E, Ewing R, Floyd Y, Gray K, Hall S, et al. Mutations of the BRAF gene in human cancer. Nature. 2002; 417(6892):949-954.
-
(2002)
Nature.
, vol.417
, Issue.6892
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
Stephens, P.4
Edkins, S.5
Clegg, S.6
Teague, J.7
Woffendin, H.8
Garnett, M.J.9
Bottomley, W.10
Davis, N.11
Dicks, E.12
Ewing, R.13
Floyd, Y.14
Gray, K.15
Hall, S.16
-
24
-
-
42949149240
-
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity
-
Tsai J, Lee JT, Wang W, Zhang J, Cho H, Mamo S, Bremer R, Gillette S, Kong J, Haass NK, Sproesser K, Li L, Smalley KS, Fong D, Zhu YL, Marimuthu A, et al. Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity. Proc Natl Acad Sci U S A. 2008; 105(8):3041-3046.
-
(2008)
Proc Natl Acad Sci U S A.
, vol.105
, Issue.8
, pp. 3041-3046
-
-
Tsai, J.1
Lee, J.T.2
Wang, W.3
Zhang, J.4
Cho, H.5
Mamo, S.6
Bremer, R.7
Gillette, S.8
Kong, J.9
Haass, N.K.10
Sproesser, K.11
Li, L.12
Smalley, K.S.13
Fong, D.14
Zhu, Y.L.15
Marimuthu, A.16
-
25
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman PB, Hauschild A, Robert C, Haanen JB, Ascierto P, Larkin J, Dummer R, Garbe C, Testori A, Maio M, Hogg D, Lorigan P, Lebbe C, Jouary T, Schadendorf D, Ribas A, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med. 2011; 364(26):2507-2516.
-
(2011)
N Engl J Med.
, vol.364
, Issue.26
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
Haanen, J.B.4
Ascierto, P.5
Larkin, J.6
Dummer, R.7
Garbe, C.8
Testori, A.9
Maio, M.10
Hogg, D.11
Lorigan, P.12
Lebbe, C.13
Jouary, T.14
Schadendorf, D.15
Ribas, A.16
-
26
-
-
78650008177
-
Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K
-
Villanueva J, Vultur A, Lee JT, Somasundaram R, Fukunaga-Kalabis M, Cipolla AK, Wubbenhorst B, Xu X, Gimotty PA, Kee D, Santiago-Walker AE, Letrero R, D'Andrea K, Pushparajan A, Hayden JE, Brown KD, et al. Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K. Cancer Cell. 2010; 18(6):683-695.
-
(2010)
Cancer Cell.
, vol.18
, Issue.6
, pp. 683-695
-
-
Villanueva, J.1
Vultur, A.2
Lee, J.T.3
Somasundaram, R.4
Fukunaga-Kalabis, M.5
Cipolla, A.K.6
Wubbenhorst, B.7
Xu, X.8
Gimotty, P.A.9
Kee, D.10
Santiago-Walker, A.E.11
Letrero, R.12
D'Andrea, K.13
Pushparajan, A.14
Hayden, J.E.15
Brown, K.D.16
-
27
-
-
33644690647
-
BRAF status and mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 activity indicate sensitivity of melanoma cells to anthrax lethal toxin
-
Abi-Habib RJ, Urieto JO, Liu S, Leppla SH, Duesbery NS and Frankel AE. BRAF status and mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 activity indicate sensitivity of melanoma cells to anthrax lethal toxin. Mol Cancer Ther. 2005; 4(9):1303-1310.
-
(2005)
Mol Cancer Ther.
, vol.4
, Issue.9
, pp. 1303-1310
-
-
Abi-Habib, R.J.1
Urieto, J.O.2
Liu, S.3
Leppla, S.H.4
Duesbery, N.S.5
Frankel, A.E.6
-
28
-
-
84890857730
-
The MEK1/2 Inhibitor AS703026 Circumvents Resistance to the BRAF Inhibitor PLX4032 in Human Malignant Melanoma Cells
-
Park SJ, Hong SW, Moon JH, Jin DH, Kim JS, Lee CK, Kim KP, Hong YS, Choi EK, Lee JS, Lee JL and Kim TW. The MEK1/2 Inhibitor AS703026 Circumvents Resistance to the BRAF Inhibitor PLX4032 in Human Malignant Melanoma Cells. Am J Med Sci. 2013; 346(6):494-498.
-
(2013)
Am J Med Sci.
, vol.346
, Issue.6
, pp. 494-498
-
-
Park, S.J.1
Hong, S.W.2
Moon, J.H.3
Jin, D.H.4
Kim, J.S.5
Lee, C.K.6
Kim, K.P.7
Hong, Y.S.8
Choi, E.K.9
Lee, J.S.10
Lee, J.L.11
Kim, T.W.12
-
29
-
-
84877114887
-
MERTK receptor tyrosine kinase is a therapeutic target in melanoma
-
Schlegel J, Sambade MJ, Sather S, Moschos SJ, Tan AC, Winges A, DeRyckere D, Carson CC, Trembath DG, Tentler JJ, Eckhardt SG, Kuan PF, Hamilton RL, Duncan LM, Miller CR, Nikolaishvili-Feinberg N, et al. MERTK receptor tyrosine kinase is a therapeutic target in melanoma. J Clin Invest. 2013; 123(5):2257-2267.
-
(2013)
J Clin Invest.
, vol.123
, Issue.5
, pp. 2257-2267
-
-
Schlegel, J.1
Sambade, M.J.2
Sather, S.3
Moschos, S.J.4
Tan, A.C.5
Winges, A.6
DeRyckere, D.7
Carson, C.C.8
Trembath, D.G.9
Tentler, J.J.10
Eckhardt, S.G.11
Kuan, P.F.12
Hamilton, R.L.13
Duncan, L.M.14
Miller, C.R.15
Nikolaishvili-Feinberg, N.16
-
30
-
-
77953735827
-
Similar nucleotide excision repair capacity in melanocytes and melanoma cells
-
Gaddameedhi S, Kemp MG, Reardon JT, Shields JM, Smith-Roe SL, Kaufmann WK and Sancar A. Similar nucleotide excision repair capacity in melanocytes and melanoma cells. Cancer Res. 2010; 70(12):4922-4930.
-
(2010)
Cancer Res.
, vol.70
, Issue.12
, pp. 4922-4930
-
-
Gaddameedhi, S.1
Kemp, M.G.2
Reardon, J.T.3
Shields, J.M.4
Smith-Roe, S.L.5
Kaufmann, W.K.6
Sancar, A.7
-
31
-
-
84861460355
-
Effects of chemotherapeutics on organotypic corticostriatal slice cultures identified by a panel of fluorescent and immunohistochemical markers
-
Norregaard A, Jensen SS, Kolenda J, Aaberg-Jessen C, Christensen KG, Jensen PH, Schroder HD and Kristensen BW. Effects of chemotherapeutics on organotypic corticostriatal slice cultures identified by a panel of fluorescent and immunohistochemical markers. Neurotox Res. 2012; 22(1):43-58.
-
(2012)
Neurotox Res.
, vol.22
, Issue.1
, pp. 43-58
-
-
Norregaard, A.1
Jensen, S.S.2
Kolenda, J.3
Aaberg-Jessen, C.4
Christensen, K.G.5
Jensen, P.H.6
Schroder, H.D.7
Kristensen, B.W.8
-
32
-
-
84864391539
-
Chloroethylnitrosourea-induced cell death and genotoxicity: cell cycle dependence and the role of DNA double-strand breaks, HR and NHEJ
-
Nikolova T, Hennekes F, Bhatti A and Kaina B. Chloroethylnitrosourea-induced cell death and genotoxicity: cell cycle dependence and the role of DNA double-strand breaks, HR and NHEJ. Cell Cycle. 2012; 11(14):2606- 2619.
-
(2012)
Cell Cycle.
, vol.11
, Issue.14
, pp. 2606- 2619
-
-
Nikolova, T.1
Hennekes, F.2
Bhatti, A.3
Kaina, B.4
-
33
-
-
0842286751
-
Apoptosis triggered by DNA damage O6-methylguanine in human lymphocytes requires DNA replication and is mediated by p53 and Fas/ CD95/Apo-1
-
Roos W, Baumgartner M and Kaina B. Apoptosis triggered by DNA damage O6-methylguanine in human lymphocytes requires DNA replication and is mediated by p53 and Fas/ CD95/Apo-1. Oncogene. 2004; 23(2):359-367.
-
(2004)
Oncogene.
, vol.23
, Issue.2
, pp. 359-367
-
-
Roos, W.1
Baumgartner, M.2
Kaina, B.3
-
34
-
-
27844567142
-
Distinct sets of genetic alterations in melanoma
-
Curtin JA, Fridlyand J, Kageshita T, Patel HN, Busam KJ, Kutzner H, Cho KH, Aiba S, Brocker EB, LeBoit PE, Pinkel D and Bastian BC. Distinct sets of genetic alterations in melanoma. N Engl J Med. 2005; 353(20):2135-2147.
-
(2005)
N Engl J Med.
, vol.353
, Issue.20
, pp. 2135-2147
-
-
Curtin, J.A.1
Fridlyand, J.2
Kageshita, T.3
Patel, H.N.4
Busam, K.J.5
Kutzner, H.6
Cho, K.H.7
Aiba, S.8
Brocker, E.B.9
LeBoit, P.E.10
Pinkel, D.11
Bastian, B.C.12
-
35
-
-
81855183767
-
Fotemustine for the treatment of melanoma
-
Quereux G and Dreno B. Fotemustine for the treatment of melanoma. Expert Opin Pharmacother. 2011; 12(18):2891- 2904.
-
(2011)
Expert Opin Pharmacother.
, vol.12
, Issue.18
, pp. 2891- 2904
-
-
Quereux, G.1
Dreno, B.2
-
36
-
-
30344463327
-
BuCy RAFs drive cells into MEK addiction
-
Rapp UR, Gotz R and Albert S. BuCy RAFs drive cells into MEK addiction. Cancer Cell. 2006; 9(1):9-12.
-
(2006)
Cancer Cell.
, vol.9
, Issue.1
, pp. 9-12
-
-
Rapp, U.R.1
Gotz, R.2
Albert, S.3
-
37
-
-
84888860816
-
Mutation landscape in melanoma patients clinical implications of heterogeneity of BRAF mutations
-
Heinzerling L, Baiter M, Kuhnapfel S, Schuler G, Keikavoussi P, Agaimy A, Kiesewetter F, Hartmann A and Schneider-Stock R. Mutation landscape in melanoma patients clinical implications of heterogeneity of BRAF mutations. Br J Cancer. 2013; 109(11):2833-2841.
-
(2013)
Br J Cancer.
, vol.109
, Issue.11
, pp. 2833-2841
-
-
Heinzerling, L.1
Baiter, M.2
Kuhnapfel, S.3
Schuler, G.4
Keikavoussi, P.5
Agaimy, A.6
Kiesewetter, F.7
Hartmann, A.8
Schneider-Stock, R.9
-
38
-
-
84863477650
-
Predictive value of the MGMT promoter methylation status in metastatic melanoma patients receiving first-line temozolomide plus bevacizumab in the trial SAKK 50/07
-
Schraml P, von Teichman A, Mihic-Probst D, Simcock M, Ochsenbein A, Dummer R, Michielin O, Seifert B, Schlappi M, Moch H and von Moos R. Predictive value of the MGMT promoter methylation status in metastatic melanoma patients receiving first-line temozolomide plus bevacizumab in the trial SAKK 50/07. Oncol Rep. 2012; 28(2):654-658.
-
(2012)
Oncol Rep.
, vol.28
, Issue.2
, pp. 654-658
-
-
Schraml, P.1
von Teichman, A.2
Mihic-Probst, D.3
Simcock, M.4
Ochsenbein, A.5
Dummer, R.6
Michielin, O.7
Seifert, B.8
Schlappi, M.9
Moch, H.10
von Moos, R.11
-
39
-
-
0028262128
-
Determination of lymphocyte division by flow cytometry
-
Lyons AB and Parish CR. Determination of lymphocyte division by flow cytometry. J Immunol Methods. 1994; 171(1):131-137.
-
(1994)
J Immunol Methods.
, vol.171
, Issue.1
, pp. 131-137
-
-
Lyons, A.B.1
Parish, C.R.2
-
40
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry. 1976; 72:248-254.
-
(1976)
Analytical Biochemistry.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
41
-
-
0028988143
-
O6-methylguanine-DNA methyltransferase activity in breast and brain tumors
-
Preuss I, Eberhagen I, Haas S, Eibl RH, Kaufmann M, von Minckwitz G and Kaina B. O6-methylguanine-DNA methyltransferase activity in breast and brain tumors. Int J Cancer. 1995; 61(3):321-326.
-
(1995)
Int J Cancer.
, vol.61
, Issue.3
, pp. 321-326
-
-
Preuss, I.1
Eberhagen, I.2
Haas, S.3
Eibl, R.H.4
Kaufmann, M.5
von Minckwitz, G.6
Kaina, B.7
-
42
-
-
35649001325
-
Intratumoral homogeneity of MGMT promoter hypermethylation as demonstrated in serial stereotactic specimens from anaplastic astrocytomas and glioblastomas
-
Grasbon-Frodl EM, Kreth FW, Ruiter M, Schnell O, Bise K, Felsberg J, Reifenberger G, Tonn JC and Kretzschmar HA. Intratumoral homogeneity of MGMT promoter hypermethylation as demonstrated in serial stereotactic specimens from anaplastic astrocytomas and glioblastomas. Int J Cancer. 2007; 121(11):2458-2464.
-
(2007)
Int J Cancer.
, vol.121
, Issue.11
, pp. 2458-2464
-
-
Grasbon-Frodl, E.M.1
Kreth, F.W.2
Ruiter, M.3
Schnell, O.4
Bise, K.5
Felsberg, J.6
Reifenberger, G.7
Tonn, J.C.8
Kretzschmar, H.A.9
-
43
-
-
0034626988
-
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
-
Esteller M, Garcia-Foncillas J, Andion E, Goodman SN, Hidalgo OF, Vanaclocha V, Baylin SB and Herman JG. Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med. 2000; 343(19):1350-1354.
-
(2000)
N Engl J Med.
, vol.343
, Issue.19
, pp. 1350-1354
-
-
Esteller, M.1
Garcia-Foncillas, J.2
Andion, E.3
Goodman, S.N.4
Hidalgo, O.F.5
Vanaclocha, V.6
Baylin, S.B.7
Herman, J.G.8
-
44
-
-
80755143421
-
Is DNA methylation an epigenetic contribution to transcriptional regulation of the bovine endometrium during the estrous cycle and early pregnancy?
-
Furst RW, Meyer HH, Schweizer G and Ulbrich SE. Is DNA methylation an epigenetic contribution to transcriptional regulation of the bovine endometrium during the estrous cycle and early pregnancy?. Mol Cell Endocrinol. 2012; 348(1):67-77.
-
(2012)
Mol Cell Endocrinol.
, vol.348
, Issue.1
, pp. 67-77
-
-
Furst, R.W.1
Meyer, H.H.2
Schweizer, G.3
Ulbrich, S.E.4
-
45
-
-
84895763591
-
DNA double strand breaks as predictor of efficacy of the alphaparticle emitter Ac-225 and the electron emitter Lu-177 for somatostatin receptor targeted radiotherapy
-
Graf F, Fahrer J, Maus S, Morgenstern A, Bruchertseifer F, Venkatachalam S, Fottner C, Weber MM, Huelsenbeck J, Schreckenberger M, Kaina B and Miederer M. DNA double strand breaks as predictor of efficacy of the alphaparticle emitter Ac-225 and the electron emitter Lu-177 for somatostatin receptor targeted radiotherapy. PLoS One. 2014; 9(2):e88239.
-
(2014)
PLoS One.
, vol.9
, Issue.2
-
-
Graf, F.1
Fahrer, J.2
Maus, S.3
Morgenstern, A.4
Bruchertseifer, F.5
Venkatachalam, S.6
Fottner, C.7
Weber, M.M.8
Huelsenbeck, J.9
Schreckenberger, M.10
Kaina, B.11
Miederer, M.12
|