-
1
-
-
84902203558
-
Type i interferon in the pathogenesis of lupus
-
M.K. Crow Type I interferon in the pathogenesis of lupus J Immunol 192 2014 5459 5468
-
(2014)
J Immunol
, vol.192
, pp. 5459-5468
-
-
Crow, M.K.1
-
2
-
-
84905456707
-
Advances in understanding the role of type i interferons in systemic lupus erythematosus
-
M.K. Crow Advances in understanding the role of type I interferons in systemic lupus erythematosus Curr Opin Rheumatol 26 2014 467 474
-
(2014)
Curr Opin Rheumatol
, vol.26
, pp. 467-474
-
-
Crow, M.K.1
-
3
-
-
0344492212
-
Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
-
E.C. Baechler, F.M. Batliwalla, and G. Karypis Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus Proc Natl Acad Sci U S A 100 2003 2610 2615
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 2610-2615
-
-
Baechler, E.C.1
Batliwalla, F.M.2
Karypis, G.3
-
4
-
-
0037451167
-
Interferon and granulopoiesis signatures in systemic lupus erythematosus blood
-
L. Bennett, A.K. Palucka, and E. Arce Interferon and granulopoiesis signatures in systemic lupus erythematosus blood J Exp Med 197 2003 711 723
-
(2003)
J Exp Med
, vol.197
, pp. 711-723
-
-
Bennett, L.1
Palucka, A.K.2
Arce, E.3
-
5
-
-
0344665750
-
Microarray analysis of interferon-regulated genes in SLE
-
M.K. Crow, K.A. Kirou, and J. Wohlgemuth Microarray analysis of interferon-regulated genes in SLE Autoimmunity 36 2003 481 490
-
(2003)
Autoimmunity
, vol.36
, pp. 481-490
-
-
Crow, M.K.1
Kirou, K.A.2
Wohlgemuth, J.3
-
6
-
-
0242456113
-
Microarray analysis of gene expression in lupus
-
M.K. Crow, and J. Wohlgemuth Microarray analysis of gene expression in lupus Arthritis Res Ther 5 2003 279 287
-
(2003)
Arthritis Res Ther
, vol.5
, pp. 279-287
-
-
Crow, M.K.1
Wohlgemuth, J.2
-
7
-
-
0141986842
-
Analysis of gene expression profiles in human systemic lupus erythematosus using oligonucleotide microarray
-
G.M. Han, S.L. Chen, and N. Shen Analysis of gene expression profiles in human systemic lupus erythematosus using oligonucleotide microarray Genes Immun 4 2003 177 186
-
(2003)
Genes Immun
, vol.4
, pp. 177-186
-
-
Han, G.M.1
Chen, S.L.2
Shen, N.3
-
8
-
-
0032950459
-
Patients with systemic lupus erythematosus (SLE) have a circulating inducer of interferon-alpha (IFN-alpha) production acting on leucocytes resembling immature dendritic cells
-
H. Vallin, S. Blomberg, and G.V. Alm Patients with systemic lupus erythematosus (SLE) have a circulating inducer of interferon-alpha (IFN-alpha) production acting on leucocytes resembling immature dendritic cells Clin Exp Immunol 115 1999 196 202
-
(1999)
Clin Exp Immunol
, vol.115
, pp. 196-202
-
-
Vallin, H.1
Blomberg, S.2
Alm, G.V.3
-
9
-
-
0035900481
-
Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus
-
P. Blanco, A.K. Palucka, and M. Gill Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus Science 294 2001 1540 1543
-
(2001)
Science
, vol.294
, pp. 1540-1543
-
-
Blanco, P.1
Palucka, A.K.2
Gill, M.3
-
10
-
-
33745034931
-
Functional assay of type i interferon in systemic lupus erythematosus plasma and association with anti-RNA binding protein autoantibodies
-
J. Hua, K. Kirou, C. Lee, and M.K. Crow Functional assay of type I interferon in systemic lupus erythematosus plasma and association with anti-RNA binding protein autoantibodies Arthritis Rheum 54 2006 1906 1916
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1906-1916
-
-
Hua, J.1
Kirou, K.2
Lee, C.3
Crow, M.K.4
-
11
-
-
78650765873
-
Interferon-alpha accelerates murine systemic lupus erythematosus in a T cell-dependent manner
-
Z. Liu, R. Bethunaickan, and W. Huang Interferon-alpha accelerates murine systemic lupus erythematosus in a T cell-dependent manner Arthritis Rheum 63 2011 219 229
-
(2011)
Arthritis Rheum
, vol.63
, pp. 219-229
-
-
Liu, Z.1
Bethunaickan, R.2
Huang, W.3
-
12
-
-
34248584526
-
Identification of distinct gene expression profiles in the synovium of patients with systemic lupus erythematosus
-
A. Nzeusseu Toukap, C. Galant, and I. Theate Identification of distinct gene expression profiles in the synovium of patients with systemic lupus erythematosus Arthritis Rheum 56 2007 1579 1588
-
(2007)
Arthritis Rheum
, vol.56
, pp. 1579-1588
-
-
Nzeusseu Toukap, A.1
Galant, C.2
Theate, I.3
-
13
-
-
38149007115
-
Glomerular accumulation of plasmacytoid dendritic cells in active lupus nephritis: Role of interleukin-18
-
M. Tucci, C. Quatraro, and L. Lombardi Glomerular accumulation of plasmacytoid dendritic cells in active lupus nephritis: role of interleukin-18 Arthritis Rheum 58 2008 251 262
-
(2008)
Arthritis Rheum
, vol.58
, pp. 251-262
-
-
Tucci, M.1
Quatraro, C.2
Lombardi, L.3
-
14
-
-
84901641596
-
Modular transcriptional repertoire analyses of adults with systemic lupus erythematosus reveal distinct type i and type II interferon signatures
-
L. Chiche, N. Jourde-Chiche, and E. Whalen Modular transcriptional repertoire analyses of adults with systemic lupus erythematosus reveal distinct type I and type II interferon signatures Arthritis Rheum 66 2014 1583 1595
-
(2014)
Arthritis Rheum
, vol.66
, pp. 1583-1595
-
-
Chiche, L.1
Jourde-Chiche, N.2
Whalen, E.3
-
15
-
-
49449104525
-
Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients
-
T.B. Niewold, J.A. Kelly, and M.H. Flesch Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients Arthritis Rheum 58 2008 2481 2487
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2481-2487
-
-
Niewold, T.B.1
Kelly, J.A.2
Flesch, M.H.3
-
16
-
-
84876282977
-
Recent insights into the genetic basis of systemic lupus erythematosus
-
O.J. Rullo, and B.P. Tsao Recent insights into the genetic basis of systemic lupus erythematosus Ann Rheum Dis 72 Suppl 2 2013 ii56 ii61
-
(2013)
Ann Rheum Dis
, vol.72
, pp. ii56-ii61
-
-
Rullo, O.J.1
Tsao, B.P.2
-
17
-
-
9644262469
-
Interferons, interferon-like cytokines, and their receptors
-
S. Pestka, C.D. Krause, and M.R. Walter Interferons, interferon-like cytokines, and their receptors Immunol Rev 202 2004 8 32
-
(2004)
Immunol Rev
, vol.202
, pp. 8-32
-
-
Pestka, S.1
Krause, C.D.2
Walter, M.R.3
-
18
-
-
84896987305
-
Interferon-stimulated genes: A complex web of host defenses
-
W.M. Schneider, M.D. Chevillotte, and C.M. Rice Interferon-stimulated genes: a complex web of host defenses Annu Rev Immunol 32 2014 513 545
-
(2014)
Annu Rev Immunol
, vol.32
, pp. 513-545
-
-
Schneider, W.M.1
Chevillotte, M.D.2
Rice, C.M.3
-
19
-
-
0035036288
-
Systemic lupus erythematosus in adults is associated with previous Epstein-Barr virus exposure
-
J.A. James, B.R. Neas, and K.L. Moser Systemic lupus erythematosus in adults is associated with previous Epstein-Barr virus exposure Arthritis Rheum 44 2001 1122 1126
-
(2001)
Arthritis Rheum
, vol.44
, pp. 1122-1126
-
-
James, J.A.1
Neas, B.R.2
Moser, K.L.3
-
20
-
-
84876311772
-
Persistent LCMV infection is controlled by blockade of type i interferon signaling
-
J.R. Teijaro, C. Ng, and A.M. Lee Persistent LCMV infection is controlled by blockade of type I interferon signaling Science 340 2013 207 211
-
(2013)
Science
, vol.340
, pp. 207-211
-
-
Teijaro, J.R.1
Ng, C.2
Lee, A.M.3
-
21
-
-
84876299371
-
Blockade of chronic type i interferon signaling to control persistent LCMV infection
-
E.B. Wilson, D.H. Yamada, and H. Elsaesser Blockade of chronic type I interferon signaling to control persistent LCMV infection Science 340 2013 202 207
-
(2013)
Science
, vol.340
, pp. 202-207
-
-
Wilson, E.B.1
Yamada, D.H.2
Elsaesser, H.3
-
22
-
-
84901008927
-
Type i interferon suppresses de novo virus-specific CD4 Th1 immunity during an established persistent viral infection
-
I. Osokine, L.M. Snell, and C.R. Cunningham Type I interferon suppresses de novo virus-specific CD4 Th1 immunity during an established persistent viral infection Proc Natl Acad Sci U S A 111 2014 7409 7414
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 7409-7414
-
-
Osokine, I.1
Snell, L.M.2
Cunningham, C.R.3
-
23
-
-
84866978487
-
Acute plasma biomarkers of T cell activation set-point levels and of disease progression in HIV-1 infection
-
A.S. Liovat, M.A. Rey-Cuille, and C. Lecuroux Acute plasma biomarkers of T cell activation set-point levels and of disease progression in HIV-1 infection PLoS One 7 2012 e46143
-
(2012)
PLoS One
, vol.7
, pp. e46143
-
-
Liovat, A.S.1
Rey-Cuille, M.A.2
Lecuroux, C.3
-
24
-
-
84885393267
-
HIV-1 infection induces strong production of IP-10 through TLR7/9-dependent pathways
-
R.P. Simmons, E.P. Scully, and E.E. Groden HIV-1 infection induces strong production of IP-10 through TLR7/9-dependent pathways AIDS 27 2013 2505 2517
-
(2013)
AIDS
, vol.27
, pp. 2505-2517
-
-
Simmons, R.P.1
Scully, E.P.2
Groden, E.E.3
-
25
-
-
84874280676
-
Interferon-alpha is the primary plasma type-I IFN in HIV-1 infection and correlates with immune activation and disease markers
-
G.A. Hardy, S. Sieg, and B. Rodriguez Interferon-alpha is the primary plasma type-I IFN in HIV-1 infection and correlates with immune activation and disease markers PLoS One 8 2013 e56527
-
(2013)
PLoS One
, vol.8
, pp. e56527
-
-
Hardy, G.A.1
Sieg, S.2
Rodriguez, B.3
-
26
-
-
20144387661
-
Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS
-
C. Kornfeld, M.J. Ploquin, and I. Pandrea Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS J Clin Invest 115 2005 1082 1091
-
(2005)
J Clin Invest
, vol.115
, pp. 1082-1091
-
-
Kornfeld, C.1
Ploquin, M.J.2
Pandrea, I.3
-
27
-
-
72849136282
-
Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type i IFN response
-
B. Jacquelin, V. Mayau, and B. Targat Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response J Clin Invest 119 2009 3544 3555
-
(2009)
J Clin Invest
, vol.119
, pp. 3544-3555
-
-
Jacquelin, B.1
Mayau, V.2
Targat, B.3
-
28
-
-
77954498359
-
Downregulation of robust acute type i interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques
-
L.D. Harris, B. Tabb, and D.L. Sodora Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques J Virol 84 2010 7886 7891
-
(2010)
J Virol
, vol.84
, pp. 7886-7891
-
-
Harris, L.D.1
Tabb, B.2
Sodora, D.L.3
-
29
-
-
84905367955
-
Innate immune responses and rapid control of inflammation in African green monkeys treated or not with interferon-alpha during primary SIVagm infection
-
B. Jacquelin, G. Petitjean, and D. Kunkel Innate immune responses and rapid control of inflammation in African green monkeys treated or not with interferon-alpha during primary SIVagm infection PLoS Pathog 10 2014 e1004241
-
(2014)
PLoS Pathog
, vol.10
, pp. e1004241
-
-
Jacquelin, B.1
Petitjean, G.2
Kunkel, D.3
-
30
-
-
84887309874
-
Kinetics of myeloid dendritic cell trafficking and activation: Impact on progressive, nonprogressive and controlled SIV infections
-
V. Wijewardana, J. Kristoff, and C. Xu Kinetics of myeloid dendritic cell trafficking and activation: impact on progressive, nonprogressive and controlled SIV infections PLoS Pathog 9 2013 e1003600
-
(2013)
PLoS Pathog
, vol.9
, pp. e1003600
-
-
Wijewardana, V.1
Kristoff, J.2
Xu, C.3
-
31
-
-
79952234401
-
Spatiotemporal trafficking of HIV in human plasmacytoid dendritic cells defines a persistently IFN-alpha-producing and partially matured phenotype
-
M. O'Brien, O. Manches, and R.L. Sabado Spatiotemporal trafficking of HIV in human plasmacytoid dendritic cells defines a persistently IFN-alpha-producing and partially matured phenotype J Clin Invest 121 2011 1088 1101
-
(2011)
J Clin Invest
, vol.121
, pp. 1088-1101
-
-
O'Brien, M.1
Manches, O.2
Sabado, R.L.3
-
32
-
-
18644384042
-
Activation of the interferon-alpha pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease
-
K.A. Kirou, C. Lee, and S. George Activation of the interferon-alpha pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease Arthritis Rheum 52 2005 1491 1503
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1491-1503
-
-
Kirou, K.A.1
Lee, C.2
George, S.3
-
33
-
-
84910640644
-
Activation of endogenous type i IFN signaling contributes to persistent HCV infection
-
Y. Li, S. Li, and X. Duan Activation of endogenous type I IFN signaling contributes to persistent HCV infection Rev Med Virol 24 2014 332 342
-
(2014)
Rev Med Virol
, vol.24
, pp. 332-342
-
-
Li, Y.1
Li, S.2
Duan, X.3
-
34
-
-
84905049001
-
Contribution of increased ISG15, ISGylation and deregulated type i IFN signaling in Usp18 mutant mice during the course of bacterial infections
-
S.M. Dauphinee, E. Richer, and M.M. Eva Contribution of increased ISG15, ISGylation and deregulated type I IFN signaling in Usp18 mutant mice during the course of bacterial infections Genes Immun 15 2014 282 292
-
(2014)
Genes Immun
, vol.15
, pp. 282-292
-
-
Dauphinee, S.M.1
Richer, E.2
Eva, M.M.3
-
35
-
-
84865585154
-
USP18 establishes the transcriptional and anti-proliferative interferon α/β differential
-
V. Francois-Newton, M. Livingstone, and B. Payelle-Brogard USP18 establishes the transcriptional and anti-proliferative interferon α/β differential Biochem J 446 2012 509 516
-
(2012)
Biochem J
, vol.446
, pp. 509-516
-
-
Francois-Newton, V.1
Livingstone, M.2
Payelle-Brogard, B.3
-
36
-
-
70350539316
-
Plasmacytoid DC promote priming of autoimmune Th17 cells and EAE
-
M. Isaksson, B. Ardesjö, and L. Rönnblom Plasmacytoid DC promote priming of autoimmune Th17 cells and EAE Eur J Immunol 39 2009 2925 2935
-
(2009)
Eur J Immunol
, vol.39
, pp. 2925-2935
-
-
Isaksson, M.1
Ardesjö, B.2
Rönnblom, L.3
-
37
-
-
84865704333
-
IL-17: A new actor in IFN-driven systemic autoimmune diseases
-
A. Ambrosi, A. Espinosa, and M. Wahren-Herlenius IL-17: a new actor in IFN-driven systemic autoimmune diseases Eur J Immunol 42 2012 2274 2284
-
(2012)
Eur J Immunol
, vol.42
, pp. 2274-2284
-
-
Ambrosi, A.1
Espinosa, A.2
Wahren-Herlenius, M.3
-
38
-
-
84887607415
-
Assessment of interferon-related biomarkers in Aicardi-Goutieres syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: A case-control study
-
G.I. Rice, G.M. Forte, and M. Szynkiewicz Assessment of interferon-related biomarkers in Aicardi-Goutieres syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study Lancet Neurol 12 2013 1159 1169
-
(2013)
Lancet Neurol
, vol.12
, pp. 1159-1169
-
-
Rice, G.I.1
Forte, G.M.2
Szynkiewicz, M.3
-
39
-
-
84868207785
-
Mutations in ADAR1 cause Aicardi-Goutieres syndrome associated with a type i interferon signature
-
G.I. Rice, P.R. Kasher, and G.M. Forte Mutations in ADAR1 cause Aicardi-Goutieres syndrome associated with a type I interferon signature Nat Genet 44 2012 1243 1248
-
(2012)
Nat Genet
, vol.44
, pp. 1243-1248
-
-
Rice, G.I.1
Kasher, P.R.2
Forte, G.M.3
-
40
-
-
84888858547
-
Aicardi-Goutieres syndrome: A model disease for systemic autoimmunity
-
M.A. Lee-Kirsch, C. Wolf, and C. Gunther Aicardi-Goutieres syndrome: a model disease for systemic autoimmunity Clin Exp Immunol 175 2014 17 24
-
(2014)
Clin Exp Immunol
, vol.175
, pp. 17-24
-
-
Lee-Kirsch, M.A.1
Wolf, C.2
Gunther, C.3
-
41
-
-
79958015275
-
Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort
-
B. Namjou, P.H. Kothari, and J.A. Kelly Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort Genes Immun 12 2011 270 279
-
(2011)
Genes Immun
, vol.12
, pp. 270-279
-
-
Namjou, B.1
Kothari, P.H.2
Kelly, J.A.3
-
42
-
-
49549100511
-
Trex1 prevents cell-intrinsic initiation of autoimmunity
-
D.B. Stetson, J.S. Ko, and T. Heidmann Trex1 prevents cell-intrinsic initiation of autoimmunity Cell 134 2008 587 598
-
(2008)
Cell
, vol.134
, pp. 587-598
-
-
Stetson, D.B.1
Ko, J.S.2
Heidmann, T.3
-
43
-
-
84905825645
-
Activated STING in a vascular and pulmonary syndrome
-
Y. Liu, A.A. Jesus, and B. Marrero Activated STING in a vascular and pulmonary syndrome N Engl J Med 371 2014 507 518
-
(2014)
N Engl J Med
, vol.371
, pp. 507-518
-
-
Liu, Y.1
Jesus, A.A.2
Marrero, B.3
-
44
-
-
84902170924
-
Activation of the STING adaptor attenuates experimental autoimmune encephalitis
-
H. Lemos, L. Huang, and P.R. Chandler Activation of the STING adaptor attenuates experimental autoimmune encephalitis J Immunol 192 2014 5571 5578
-
(2014)
J Immunol
, vol.192
, pp. 5571-5578
-
-
Lemos, H.1
Huang, L.2
Chandler, P.R.3
-
45
-
-
0034059382
-
Comparison of the validity and sensitivity to change of 5 activity indices in systemic lupus erythematosus
-
M.M. Ward, A.S. Marx, and N.N. Barry Comparison of the validity and sensitivity to change of 5 activity indices in systemic lupus erythematosus J Rheumatol 27 2000 664 670
-
(2000)
J Rheumatol
, vol.27
, pp. 664-670
-
-
Ward, M.M.1
Marx, A.S.2
Barry, N.N.3
-
46
-
-
22844439577
-
BILAG 2004. Development and initial validation of an updated version of the British Isles Lupus Assessment Group's disease activity index for patients with systemic lupus erythematosus
-
D.A. Isenberg, A. Rahman, and E. Allen BILAG 2004. Development and initial validation of an updated version of the British Isles Lupus Assessment Group's disease activity index for patients with systemic lupus erythematosus Rheumatology (Oxford) 44 2005 902 906
-
(2005)
Rheumatology (Oxford)
, vol.44
, pp. 902-906
-
-
Isenberg, D.A.1
Rahman, A.2
Allen, E.3
-
47
-
-
84921358898
-
High type i interferon in systemic lupus erythematosus plasma predicts future renal disease
-
M. Olferiev, E. Jacek, and M. Lliguicota High type I interferon in systemic lupus erythematosus plasma predicts future renal disease Arthritis Rheum 65 2013 1572
-
(2013)
Arthritis Rheum
, vol.65
, pp. 1572
-
-
Olferiev, M.1
Jacek, E.2
Lliguicota, M.3
-
48
-
-
84871122731
-
Anti-IFN-alpha/beta receptor antibody treatment ameliorates disease in lupus-predisposed mice
-
R. Baccala, R. Gonzalez-Quintial, and R.D. Schreiber Anti-IFN-alpha/beta receptor antibody treatment ameliorates disease in lupus-predisposed mice J Immunol 189 2012 5976 5984
-
(2012)
J Immunol
, vol.189
, pp. 5976-5984
-
-
Baccala, R.1
Gonzalez-Quintial, R.2
Schreiber, R.D.3
-
49
-
-
84885409854
-
IFNα inducible models of murine SLE
-
Z. Liu, and A. Davidson IFNα inducible models of murine SLE Front Immunol 4 2013 306
-
(2013)
Front Immunol
, vol.4
, pp. 306
-
-
Liu, Z.1
Davidson, A.2
-
50
-
-
84904260556
-
Interferon alpha on NZM2328.Lc1R27: Enhancing autoimmunity and immune complex-mediated glomerulonephritis without end stage renal failure
-
C. Dai, H. Wang, and S.S. Sung Interferon alpha on NZM2328.Lc1R27: enhancing autoimmunity and immune complex-mediated glomerulonephritis without end stage renal failure Clin Immunol 154 2014 66 71
-
(2014)
Clin Immunol
, vol.154
, pp. 66-71
-
-
Dai, C.1
Wang, H.2
Sung, S.S.3
-
51
-
-
84888857656
-
Glomerular expression of myxovirus resistance protein 1 in human mesangial cells: Possible activation of innate immunity in the pathogenesis of lupus nephritis
-
S. Watanabe, T. Imaizumi, and K. Tsuruga Glomerular expression of myxovirus resistance protein 1 in human mesangial cells: possible activation of innate immunity in the pathogenesis of lupus nephritis Nephrology (Carlton) 18 2013 833 837
-
(2013)
Nephrology (Carlton)
, vol.18
, pp. 833-837
-
-
Watanabe, S.1
Imaizumi, T.2
Tsuruga, K.3
-
52
-
-
84881097754
-
Anti-interferon alpha treatment in SLE
-
K.A. Kirou, and E. Gkrouzman Anti-interferon alpha treatment in SLE Clin Immunol 148 2013 303 312
-
(2013)
Clin Immunol
, vol.148
, pp. 303-312
-
-
Kirou, K.A.1
Gkrouzman, E.2
-
53
-
-
66449097622
-
Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase i trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus
-
Y. Yao, L. Richman, and B.W. Higgs Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus Arthritis Rheum 60 2009 1785 1796
-
(2009)
Arthritis Rheum
, vol.60
, pp. 1785-1796
-
-
Yao, Y.1
Richman, L.2
Higgs, B.W.3
-
54
-
-
80053562466
-
Safety profile and clinical activity of sifalimumab, a fully human anti-interferon alpha monoclonal antibody, in systemic lupus erythematosus: A phase I, multicentre, double-blind randomised study
-
J.T. Merrill, D.J. Wallace, and M. Petri Safety profile and clinical activity of sifalimumab, a fully human anti-interferon alpha monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study Ann Rheum Dis 70 2011 1905 1913
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 1905-1913
-
-
Merrill, J.T.1
Wallace, D.J.2
Petri, M.3
-
55
-
-
84875697484
-
Sifalimumab, a human anti-interferon-alpha monoclonal antibody, in systemic lupus erythematosus: A phase i randomized, controlled, dose-escalation study
-
M. Petri, D.J. Wallace, and A. Spindler Sifalimumab, a human anti-interferon-alpha monoclonal antibody, in systemic lupus erythematosus: a phase I randomized, controlled, dose-escalation study Arthritis Rheum 65 2013 1011 1021
-
(2013)
Arthritis Rheum
, vol.65
, pp. 1011-1021
-
-
Petri, M.1
Wallace, D.J.2
Spindler, A.3
-
56
-
-
84868144947
-
Safety and pharmacodynamics of rontalizumab in patients with systemic lupus erythematosus: Results of a phase I, placebo-controlled, double-blind, dose-escalation study
-
J.M. McBride, J. Jiang, and A.R. Abbas Safety and pharmacodynamics of rontalizumab in patients with systemic lupus erythematosus: results of a phase I, placebo-controlled, double-blind, dose-escalation study Arthritis Rheum 64 2012 3666 3676
-
(2012)
Arthritis Rheum
, vol.64
, pp. 3666-3676
-
-
McBride, J.M.1
Jiang, J.2
Abbas, A.R.3
-
57
-
-
76249118401
-
A randomized, double-blind, placebo-controlled, phase i study of MEDI-545, an anti-interferon-alfa monoclonal antibody, in subjects with chronic psoriasis
-
R. Bissonnette, K. Papp, and C. Maari A randomized, double-blind, placebo-controlled, phase I study of MEDI-545, an anti-interferon-alfa monoclonal antibody, in subjects with chronic psoriasis J Am Acad Dermatol 62 2010 427 436
-
(2010)
J Am Acad Dermatol
, vol.62
, pp. 427-436
-
-
Bissonnette, R.1
Papp, K.2
Maari, C.3
-
58
-
-
84873870755
-
Down-regulation of interferon signature in systemic lupus erythematosus patients by active immunization with interferon alpha-kinoid
-
B.R. Lauwerys, E. Hachulla, and F. Spertini Down-regulation of interferon signature in systemic lupus erythematosus patients by active immunization with interferon alpha-kinoid Arthritis Rheum 65 2013 447 456
-
(2013)
Arthritis Rheum
, vol.65
, pp. 447-456
-
-
Lauwerys, B.R.1
Hachulla, E.2
Spertini, F.3
-
59
-
-
84878228166
-
Pharmacogenomics and translational simulations to bridge indications for an anti-interferon-alpha receptor antibody
-
B. Wang, B.W. Higgs, and L. Chang Pharmacogenomics and translational simulations to bridge indications for an anti-interferon-alpha receptor antibody Clin Pharmacol Ther 93 2013 483 492
-
(2013)
Clin Pharmacol Ther
, vol.93
, pp. 483-492
-
-
Wang, B.1
Higgs, B.W.2
Chang, L.3
-
60
-
-
47249092785
-
Development of TLR inhibitors for the treatment of autoimmune diseases
-
F.J. Barrat, and R.L. Coffman Development of TLR inhibitors for the treatment of autoimmune diseases Immunol Rev 223 2008 271 283
-
(2008)
Immunol Rev
, vol.223
, pp. 271-283
-
-
Barrat, F.J.1
Coffman, R.L.2
-
61
-
-
37549066665
-
Treatment of lupus-prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms
-
F.J. Barrat, T. Meeker, and J.H. Chan Treatment of lupus-prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms Eur J Immunol 37 2007 3582 3586
-
(2007)
Eur J Immunol
, vol.37
, pp. 3582-3586
-
-
Barrat, F.J.1
Meeker, T.2
Chan, J.H.3
-
62
-
-
84874853444
-
Increased ribonuclease expression reduces inflammation and prolongs survival in TLR7 transgenic mice
-
X. Sun, A. Wiedeman, and N. Agrawal Increased ribonuclease expression reduces inflammation and prolongs survival in TLR7 transgenic mice J Immunol 190 2013 2536 2543
-
(2013)
J Immunol
, vol.190
, pp. 2536-2543
-
-
Sun, X.1
Wiedeman, A.2
Agrawal, N.3
-
63
-
-
84876067752
-
Design, synthesis and biological evaluation of novel antagonist compounds of Toll-like receptors 7, 8 and 9
-
E.R. Kandimalla, L. Bhagat, and D. Wang Design, synthesis and biological evaluation of novel antagonist compounds of Toll-like receptors 7, 8 and 9 Nucleic Acids Res 41 2013 3947 3961
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 3947-3961
-
-
Kandimalla, E.R.1
Bhagat, L.2
Wang, D.3
-
64
-
-
84862752020
-
Hydroxychloroquine is associated with impaired interferon-alpha and tumor necrosis factor-alpha production by plasmacytoid dendritic cells in systemic lupus erythematosus
-
K. Sacre, L.A. Criswell, and J.M. McCune Hydroxychloroquine is associated with impaired interferon-alpha and tumor necrosis factor-alpha production by plasmacytoid dendritic cells in systemic lupus erythematosus Arthritis Res Ther 14 2012 R155
-
(2012)
Arthritis Res Ther
, vol.14
, pp. R155
-
-
Sacre, K.1
Criswell, L.A.2
McCune, J.M.3
-
65
-
-
39549116503
-
PI3K is critical for the nuclear translocation of IRF-7 and type i IFN production by human plasmacytoid predendritic cells in response to TLR activation
-
C. Guiducci, C. Ghirelli, and M.A. Marloie-Provost PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation J Exp Med 205 2008 315 322
-
(2008)
J Exp Med
, vol.205
, pp. 315-322
-
-
Guiducci, C.1
Ghirelli, C.2
Marloie-Provost, M.A.3
-
66
-
-
77956256590
-
Jak/STAT signaling is involved in the inflammatory infiltration of the kidneys in MRL/lpr mice
-
S. Wang, N. Yang, and L. Zhang Jak/STAT signaling is involved in the inflammatory infiltration of the kidneys in MRL/lpr mice Lupus 19 2010 1171 1180
-
(2010)
Lupus
, vol.19
, pp. 1171-1180
-
-
Wang, S.1
Yang, N.2
Zhang, L.3
|