Replication-defective HSV-1 effectively targets trigeminal ganglion and inhibits viral pathopoiesis by mediating interferon gamma expression in SH-SY5Y cells

Journal of Molecular Neuroscience

Volumn 53, Issue 1, 2014, Pages 78-86

  Xu, Kun ^a,b   Liu, Xian Ning ^a,b   Zhang, Hong Bing ^a   An, Na ^a,b   Wang, Yao ^a,b   Zhang, Zhi Chao ^c   Wang, Ya Ni ^a,b  

^a No 1 Hospital of xi'An   (China)

^b Shaanxi Provincial Key Laboratory of Ophthalmology   (China)

^c MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

Herpes simplex keratitis; Interferon gamma; Replication defective HSV 1 vector; Trigeminal ganglion

Indexed keywords

ACICLOVIR; GAMMA INTERFERON; GLYCOPROTEIN D; MESSENGER RNA; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CELL MEDIATED CYTOTOXICITY; CONTROLLED STUDY; FEMALE; HERPES SIMPLEX KERATITIS; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; IMMUNIZATION; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TARGET ORGAN; TRIGEMINUS GANGLION; VIRUS INHIBITION; VIRUS SURVIVAL; WESTERN BLOTTING; ANIMAL; GENE THERAPY; GENE VECTOR; GENETICS; KERATITIS, HERPETIC; METABOLISM; TUMOR CELL LINE; WISTAR RAT;

HERPES; HUMAN HERPESVIRUS 1; RATTUS; RATTUS NORVEGICUS;

ANIMALS; CELL LINE, TUMOR; FEMALE; GENETIC THERAPY; GENETIC VECTORS; HERPESVIRUS 1, HUMAN; HUMANS; INTERFERON-GAMMA; KERATITIS, HERPETIC; RATS; RATS, WISTAR; TRIGEMINAL GANGLION;

EID: 84899939680     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-013-0199-x     Document Type: Article

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