IGFBP-3 inhibits TNF-α production and TNFR-2 signaling to protect against Retinal Endothelial Cell Apoptosis

Microvascular Research

Volumn 95, Issue 1, 2014, Pages 76-81

  Zhang, Qiuhua ^a   Steinle, Jena J ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Apoptosis; C Jun; Diabetic retinopathy; IGFBP 3; TNFalpha

Indexed keywords

LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; PROTEIN C JUN; SOMATOMEDIN BINDING PROTEIN 3; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; ADAM PROTEIN; IGFBP3 PROTEIN, HUMAN; LRP1 PROTEIN, HUMAN; STRESS ACTIVATED PROTEIN KINASE; TIMP3 PROTEIN, HUMAN; TNFRSF1B PROTEIN, HUMAN; TUMOR NECROSIS FACTOR RECEPTOR 2; TUMOR NECROSIS FACTOR-ALPHA CONVERTASE;

ANTIGEN ANTIBODY COMPLEX; APOPTOSIS; ARTICLE; BINDING SITE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIABETIC RETINOPATHY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; PLASMID; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RETINA CELL; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; WESTERN BLOTTING; CELL CULTURE; GENETIC TRANSFECTION; GENETICS; METABOLISM; PATHOLOGY; RETINA BLOOD VESSEL;

ADAM PROTEINS; APOPTOSIS; CELLS, CULTURED; DIABETIC RETINOPATHY; ENDOTHELIAL CELLS; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-1; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; RETINAL VESSELS; SIGNAL TRANSDUCTION; TISSUE INHIBITOR OF METALLOPROTEINASE-3; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84921294177     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2014.07.009     Document Type: Article

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