메뉴 건너뛰기




Volumn 59, Issue 1, 2015, Pages 147-159

Resveratrol treatment as an adjunct to pharmacological management in type 2 diabetes mellitus-systematic review and meta-analysis

Author keywords

Cardiometabolic; French paradox; Nutraceutical; SIRT1; Sirtuin

Indexed keywords

ANIMALIA;

EID: 84921033588     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201400173     Document Type: Review
Times cited : (143)

References (53)
  • 1
    • 73749083481 scopus 로고    scopus 로고
    • Global estimates of the prevalence of diabetes for 2010 and 2030
    • Shaw, J. E., Sicree, R. A., Zimmet, P. Z., Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res. Clin. Pract. 2010, 87, 4-14.
    • (2010) Diabetes Res. Clin. Pract. , vol.87 , pp. 4-14
    • Shaw, J.E.1    Sicree, R.A.2    Zimmet, P.Z.3
  • 2
    • 79960262492 scopus 로고    scopus 로고
    • Management of type 2 diabetes: new and future developments in treatment
    • Tahrani, A. A., Bailey, C. J., Del Prato, S., Barnett, A. H., Management of type 2 diabetes: new and future developments in treatment. Lancet 2011, 378, 182-197.
    • (2011) Lancet , vol.378 , pp. 182-197
    • Tahrani, A.A.1    Bailey, C.J.2    Del Prato, S.3    Barnett, A.H.4
  • 3
    • 84555195156 scopus 로고    scopus 로고
    • Nutrient sensing, autophagy, and diabetic nephropathy
    • Kume, S., Thomas, M. C., Koya, D., Nutrient sensing, autophagy, and diabetic nephropathy. Diabetes 2012, 61, 23-29.
    • (2012) Diabetes , vol.61 , pp. 23-29
    • Kume, S.1    Thomas, M.C.2    Koya, D.3
  • 4
    • 84859977895 scopus 로고    scopus 로고
    • Sirtuins mediate mammalian metabolic responses to nutrient availability
    • Chalkiadaki, A., Guarente, L., Sirtuins mediate mammalian metabolic responses to nutrient availability. Nat. Rev. Endocrinol. 2012, 8, 287-296.
    • (2012) Nat. Rev. Endocrinol. , vol.8 , pp. 287-296
    • Chalkiadaki, A.1    Guarente, L.2
  • 5
    • 84861852370 scopus 로고    scopus 로고
    • Are sirtuins viable targets for improving healthspan and lifespan?
    • Baur, J. A., Ungvari, Z., Minor, R. K., Le Couteur, D. G. et al., Are sirtuins viable targets for improving healthspan and lifespan? Nat. Rev. Drug Discov. 2012, 11, 443-461.
    • (2012) Nat. Rev. Drug Discov. , vol.11 , pp. 443-461
    • Baur, J.A.1    Ungvari, Z.2    Minor, R.K.3    Le Couteur, D.G.4
  • 6
    • 84860920123 scopus 로고    scopus 로고
    • Of mice and men: the benefits of caloric restriction, exercise, and mimetics
    • Mercken, E. M., Carboneau, B. A., Krzysik-Walker, S. M., de Cabo, R., Of mice and men: the benefits of caloric restriction, exercise, and mimetics. Ageing Res. Rev. 2012, 11, 390-398.
    • (2012) Ageing Res. Rev. , vol.11 , pp. 390-398
    • Mercken, E.M.1    Carboneau, B.A.2    Krzysik-Walker, S.M.3    de Cabo, R.4
  • 7
    • 0034773404 scopus 로고    scopus 로고
    • Role of AMP-activated protein kinase in mechanism of metformin action
    • Zhou, G., Myers, R., Li, Y., Chen, Y. et al., Role of AMP-activated protein kinase in mechanism of metformin action. J. Clin. Invest. 2001, 108, 1167-1174.
    • (2001) J. Clin. Invest. , vol.108 , pp. 1167-1174
    • Zhou, G.1    Myers, R.2    Li, Y.3    Chen, Y.4
  • 8
    • 84555188488 scopus 로고    scopus 로고
    • Sirtuin 1-mediated cellular metabolic memory of high glucose via the LKB1/AMPK/ROS pathway and therapeutic effects of metformin
    • Zheng, Z., Chen, H., Li, J., Li, T. et al., Sirtuin 1-mediated cellular metabolic memory of high glucose via the LKB1/AMPK/ROS pathway and therapeutic effects of metformin. Diabetes 2013, 61, 217-228.
    • (2013) Diabetes , vol.61 , pp. 217-228
    • Zheng, Z.1    Chen, H.2    Li, J.3    Li, T.4
  • 9
    • 0141719702 scopus 로고    scopus 로고
    • Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
    • Howitz, K. T., Bitterman, K. J., Cohen, H. Y., Lamming, D. W. et al., Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 2003, 425, 191-196.
    • (2003) Nature , vol.425 , pp. 191-196
    • Howitz, K.T.1    Bitterman, K.J.2    Cohen, H.Y.3    Lamming, D.W.4
  • 10
    • 84863011114 scopus 로고    scopus 로고
    • Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases
    • Park, S. J., Ahmad, F., Philp, A., Baar, K. et al., Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases. Cell 2012, 148, 421-433.
    • (2012) Cell , vol.148 , pp. 421-433
    • Park, S.J.1    Ahmad, F.2    Philp, A.3    Baar, K.4
  • 11
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: the in vivo evidence
    • Baur, J. A., Sinclair, D. A., Therapeutic potential of resveratrol: the in vivo evidence. Nat. Rev. Drug Discov. 2006, 5, 493-506.
    • (2006) Nat. Rev. Drug Discov. , vol.5 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 12
    • 36749087548 scopus 로고    scopus 로고
    • Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
    • Milne, J. C., Lambert, P. D., Schenk, S., Carney, D. P. et al., Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature 2007, 450, 712-716.
    • (2007) Nature , vol.450 , pp. 712-716
    • Milne, J.C.1    Lambert, P.D.2    Schenk, S.3    Carney, D.P.4
  • 13
    • 79956021270 scopus 로고    scopus 로고
    • Improving glucose metabolism with resveratrol in a swine model of metabolic syndrome through alteration of signaling pathways in the liver and skeletal muscle
    • Burgess, T. A., Robich, M. P., Chu, L. M., Bianchi, C. et al., Improving glucose metabolism with resveratrol in a swine model of metabolic syndrome through alteration of signaling pathways in the liver and skeletal muscle. Arch. Surg. 2011, 146, 556-564.
    • (2011) Arch. Surg. , vol.146 , pp. 556-564
    • Burgess, T.A.1    Robich, M.P.2    Chu, L.M.3    Bianchi, C.4
  • 14
    • 84859154631 scopus 로고    scopus 로고
    • Effects of chronic calorie restriction or dietary resveratrol supplementation on insulin sensitivity markers in a primate, Microcebus murinus
    • Marchal, J., Blanc, S., Epelbaum, J., Aujard, F. et al., Effects of chronic calorie restriction or dietary resveratrol supplementation on insulin sensitivity markers in a primate, Microcebus murinus. PLoS One 2012, 7, e34289.
    • (2012) PLoS One , vol.7 , pp. e34289
    • Marchal, J.1    Blanc, S.2    Epelbaum, J.3    Aujard, F.4
  • 15
    • 84885132460 scopus 로고    scopus 로고
    • Resveratrol prevents beta-cell dedifferentiation in non-human primates given a high fat/high sugar diet
    • Fiori, J. L., Shin, Y. K., Kim, W., Krzysik-Walker, S. M. et al., Resveratrol prevents beta-cell dedifferentiation in non-human primates given a high fat/high sugar diet. Diabetes 2013, 62, 3500-3513.
    • (2013) Diabetes , vol.62 , pp. 3500-3513
    • Fiori, J.L.1    Shin, Y.K.2    Kim, W.3    Krzysik-Walker, S.M.4
  • 16
    • 84873947174 scopus 로고    scopus 로고
    • Synergistic effects of metformin, resveratrol, and hydroxymethylbutyrate on insulin sensitivity
    • Bruckbauer, A., Zemel, M. B., Synergistic effects of metformin, resveratrol, and hydroxymethylbutyrate on insulin sensitivity. Diabetes Metab. Syndr. Obes. 2013, 6, 93-102.
    • (2013) Diabetes Metab. Syndr. Obes. , vol.6 , pp. 93-102
    • Bruckbauer, A.1    Zemel, M.B.2
  • 17
    • 79961047423 scopus 로고    scopus 로고
    • Resveratrol and health-a comprehensive review of human clinical trials
    • Smoliga, J. M., Baur, J. A., Hausenblas, H. A., Resveratrol and health-a comprehensive review of human clinical trials. Mol. Nutr. Food Res. 2011, 55, 1129-1141.
    • (2011) Mol. Nutr. Food Res. , vol.55 , pp. 1129-1141
    • Smoliga, J.M.1    Baur, J.A.2    Hausenblas, H.A.3
  • 18
    • 84881104932 scopus 로고    scopus 로고
    • A healthier approach to clinical trials evaluating resveratrol for primary prevention of age-related diseases in healthy populations
    • Smoliga, J. M., Colombo, E. S., Campen, M. J., A healthier approach to clinical trials evaluating resveratrol for primary prevention of age-related diseases in healthy populations. Aging 2013, 5, 495-506.
    • (2013) Aging , vol.5 , pp. 495-506
    • Smoliga, J.M.1    Colombo, E.S.2    Campen, M.J.3
  • 19
    • 68549101842 scopus 로고    scopus 로고
    • The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration
    • Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C. et al., The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ 2009, 339, b2700.
    • (2009) BMJ , vol.339 , pp. b2700
    • Liberati, A.1    Altman, D.G.2    Tetzlaff, J.3    Mulrow, C.4
  • 20
    • 3543040900 scopus 로고
    • Writing meta-analytic reviews
    • Rosenthal, R., Writing meta-analytic reviews. Psychol. Bull. 1995, 118, 1173-1181.
    • (1995) Psychol. Bull. , vol.118 , pp. 1173-1181
    • Rosenthal, R.1
  • 21
    • 0029914622 scopus 로고    scopus 로고
    • Assessing the quality of reports of randomized clinical trials: is blinding necessary?
    • Jadad, A. R., Moore, R. A., Carroll, D., Jenkinson, C. et al., Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin. Trials 1996, 17, 1-12.
    • (1996) Control Clin. Trials , vol.17 , pp. 1-12
    • Jadad, A.R.1    Moore, R.A.2    Carroll, D.3    Jenkinson, C.4
  • 22
    • 84862302106 scopus 로고    scopus 로고
    • Effectiveness of quality improvement strategies on the management of diabetes: a systematic review and meta-analysis
    • Tricco, A. C., Ivers, N. M., Grimshaw, J. M., Moher, D. et al., Effectiveness of quality improvement strategies on the management of diabetes: a systematic review and meta-analysis. Lancet 2012, 379, 2252-2261.
    • (2012) Lancet , vol.379 , pp. 2252-2261
    • Tricco, A.C.1    Ivers, N.M.2    Grimshaw, J.M.3    Moher, D.4
  • 23
    • 0041876133 scopus 로고    scopus 로고
    • Measuring inconsistency in meta-analyses
    • Higgins, J. P., Thompson, S. G., Deeks, J. J., Altman, D. G., Measuring inconsistency in meta-analyses. BMJ 2003, 327, 557-560.
    • (2003) BMJ , vol.327 , pp. 557-560
    • Higgins, J.P.1    Thompson, S.G.2    Deeks, J.J.3    Altman, D.G.4
  • 26
    • 84865181393 scopus 로고    scopus 로고
    • Resveratrol supplementation improves glycemic control in type 2 diabetes mellitus
    • Bhatt, J. K., Thomas, S., Nanjan, M. J., Resveratrol supplementation improves glycemic control in type 2 diabetes mellitus. Nutr. Res. 2012, 32, 537-541.
    • (2012) Nutr. Res. , vol.32 , pp. 537-541
    • Bhatt, J.K.1    Thomas, S.2    Nanjan, M.J.3
  • 27
    • 84906490962 scopus 로고    scopus 로고
    • Resveratrol supplementation in patients with type 2 diabetes mellitus: a prospective, open label, randomized controlled trial
    • Kumar, B. J., Joghee, N. M., Resveratrol supplementation in patients with type 2 diabetes mellitus: a prospective, open label, randomized controlled trial. Int. Res. J. Pharm. 2013, 4, 245-249.
    • (2013) Int. Res. J. Pharm. , vol.4 , pp. 245-249
    • Kumar, B.J.1    Joghee, N.M.2
  • 29
    • 84877002108 scopus 로고    scopus 로고
    • One-year supplementation with a grape extract containing resveratrol modulates inflammatory-related microRNAs and cytokines expression in peripheral blood mononuclear cells of type 2 diabetes and hypertensive patients with coronary artery disease
    • Tome-Carneiro, J., Larrosa, M., Yanez-Gascon, M. J., Davalos, A. et al., One-year supplementation with a grape extract containing resveratrol modulates inflammatory-related microRNAs and cytokines expression in peripheral blood mononuclear cells of type 2 diabetes and hypertensive patients with coronary artery disease. Pharmacol. Res. 2013, 72, 69-82.
    • (2013) Pharmacol. Res. , vol.72 , pp. 69-82
    • Tome-Carneiro, J.1    Larrosa, M.2    Yanez-Gascon, M.J.3    Davalos, A.4
  • 30
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
    • UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998, 352, 837-853.
    • (1998) Lancet , vol.352 , pp. 837-853
  • 31
    • 0034641568 scopus 로고    scopus 로고
    • Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study
    • Stratton, I. M., Adler, A. I., Neil, H. A., Matthews, D. R. et al., Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. BMJ 2000, 321, 405-412.
    • (2000) BMJ , vol.321 , pp. 405-412
    • Stratton, I.M.1    Adler, A.I.2    Neil, H.A.3    Matthews, D.R.4
  • 32
    • 0037426396 scopus 로고    scopus 로고
    • Relationships between low-density lipoprotein particle size, plasma lipoproteins, and progression of coronary artery disease: the Diabetes Atherosclerosis Intervention Study (DAIS)
    • Vakkilainen, J., Steiner, G., Ansquer, J. C., Aubin, F. et al., Relationships between low-density lipoprotein particle size, plasma lipoproteins, and progression of coronary artery disease: the Diabetes Atherosclerosis Intervention Study (DAIS). Circulation 2003, 107, 1733-1737.
    • (2003) Circulation , vol.107 , pp. 1733-1737
    • Vakkilainen, J.1    Steiner, G.2    Ansquer, J.C.3    Aubin, F.4
  • 33
    • 0033533807 scopus 로고    scopus 로고
    • Nephropathy in patients with type 2 diabetes mellitus
    • Ritz, E., Orth, S. R., Nephropathy in patients with type 2 diabetes mellitus. N. Engl. J. Med. 1999, 341, 1127-1133.
    • (1999) N. Engl. J. Med. , vol.341 , pp. 1127-1133
    • Ritz, E.1    Orth, S.R.2
  • 34
    • 0037213037 scopus 로고    scopus 로고
    • Development and progression of nephropathy in type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS 64)
    • Adler, A. I., Stevens, R. J., Manley, S. E., Bilous, R. W. et al., Development and progression of nephropathy in type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS 64). Kidney Int. 2003, 63, 225-232.
    • (2003) Kidney Int. , vol.63 , pp. 225-232
    • Adler, A.I.1    Stevens, R.J.2    Manley, S.E.3    Bilous, R.W.4
  • 35
    • 0032507776 scopus 로고    scopus 로고
    • Main risk factors for nephropathy in type 2 diabetes mellitus are plasma cholesterol levels, mean blood pressure, and hyperglycemia
    • Ravid, M., Brosh, D., Ravid-Safran, D., Levy, Z. et al., Main risk factors for nephropathy in type 2 diabetes mellitus are plasma cholesterol levels, mean blood pressure, and hyperglycemia. Arch. Int. Med. 1998, 158, 998-1004.
    • (1998) Arch. Int. Med. , vol.158 , pp. 998-1004
    • Ravid, M.1    Brosh, D.2    Ravid-Safran, D.3    Levy, Z.4
  • 36
    • 33748309114 scopus 로고    scopus 로고
    • Risk factors for renal dysfunction in type 2 diabetes: U.K. Prospective Diabetes Study 74
    • Retnakaran, R., Cull, C. A., Thorne, K. I., Adler, A. I. et al., Risk factors for renal dysfunction in type 2 diabetes: U.K. Prospective Diabetes Study 74. Diabetes 2006, 55, 1832-1839.
    • (2006) Diabetes , vol.55 , pp. 1832-1839
    • Retnakaran, R.1    Cull, C.A.2    Thorne, K.I.3    Adler, A.I.4
  • 37
    • 77953032816 scopus 로고    scopus 로고
    • Effects of resveratrol on cerebral blood flow variables and cognitive performance in humans: a double-blind, placebo-controlled, crossover investigation
    • Kennedy, D. O., Wightman, E. L., Reay, J. L., Lietz, G. et al., Effects of resveratrol on cerebral blood flow variables and cognitive performance in humans: a double-blind, placebo-controlled, crossover investigation. Am. J. Clin. Nutr. 2010, 91, 1590-1597.
    • (2010) Am. J. Clin. Nutr. , vol.91 , pp. 1590-1597
    • Kennedy, D.O.1    Wightman, E.L.2    Reay, J.L.3    Lietz, G.4
  • 38
    • 84950170835 scopus 로고    scopus 로고
    • Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure
    • Wong, R. H., Howe, P. R., Buckley, J. D., Coates, A. M. et al., Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure. Nutr. Metab. Cardiovasc. Dis. 2011, 21, 851-856.
    • (2011) Nutr. Metab. Cardiovasc. Dis. , vol.21 , pp. 851-856
    • Wong, R.H.1    Howe, P.R.2    Buckley, J.D.3    Coates, A.M.4
  • 39
    • 0037067666 scopus 로고    scopus 로고
    • The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways
    • Fryer, L. G., Parbu-Patel, A., Carling, D., The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways. J. Biol. Chem. 2002, 277, 25226-25232.
    • (2002) J. Biol. Chem. , vol.277 , pp. 25226-25232
    • Fryer, L.G.1    Parbu-Patel, A.2    Carling, D.3
  • 40
    • 79954424091 scopus 로고    scopus 로고
    • Cyclodextrin-based nanosponges for delivery of resveratrol: in vitro characterisation, stability, cytotoxicity and permeation study
    • Ansari, K. A., Vavia, P. R., Trotta, F., Cavalli, R., Cyclodextrin-based nanosponges for delivery of resveratrol: in vitro characterisation, stability, cytotoxicity and permeation study. AAPS PharmSci. 2011, 12, 279-286.
    • (2011) AAPS PharmSci. , vol.12 , pp. 279-286
    • Ansari, K.A.1    Vavia, P.R.2    Trotta, F.3    Cavalli, R.4
  • 41
    • 84868282379 scopus 로고    scopus 로고
    • Development of novel cationic chitosan and anionic alginate-coated poly(D,L-lactide-co-glycolide) nanoparticles for controlled release and light protection of resveratrol
    • Sanna, V., Roggio, A. M., Siliani, S., Piccinini, M. et al., Development of novel cationic chitosan and anionic alginate-coated poly(D, L-lactide-co-glycolide) nanoparticles for controlled release and light protection of resveratrol. Int. J. Nanomed. 2012, 7, 5501-5516.
    • (2012) Int. J. Nanomed. , vol.7 , pp. 5501-5516
    • Sanna, V.1    Roggio, A.M.2    Siliani, S.3    Piccinini, M.4
  • 42
    • 84856171338 scopus 로고    scopus 로고
    • Challenges of translating basic research into therapeutics: resveratrol as an example
    • Smoliga, J. M., Vang, O., Baur, J. A., Challenges of translating basic research into therapeutics: resveratrol as an example. J. Gerontol. A Biol. Sci. Med. Sci. 2012, 67, 158-167.
    • (2012) J. Gerontol. A Biol. Sci. Med. Sci. , vol.67 , pp. 158-167
    • Smoliga, J.M.1    Vang, O.2    Baur, J.A.3
  • 43
    • 34250901592 scopus 로고    scopus 로고
    • Phase I dose escalation pharmacokinetic study in healthy volunteers of resveratrol, a potential cancer chemoprotective agent
    • Boocock, D. J., Faust, G. E. S., Patel, K. R., Schinas, A. M. et al., Phase I dose escalation pharmacokinetic study in healthy volunteers of resveratrol, a potential cancer chemoprotective agent. Cancer Epidemiol. Biomark. Prev. 2007, 16, 1246-1252.
    • (2007) Cancer Epidemiol. Biomark. Prev. , vol.16 , pp. 1246-1252
    • Boocock, D.J.1    Faust, G.E.S.2    Patel, K.R.3    Schinas, A.M.4
  • 44
    • 84873996774 scopus 로고    scopus 로고
    • A phase 2 study of SRT501 (resveratrol) with bortezomib for patients with relapsed and or refractory multiple myeloma
    • Popat, R., Plesner, T., Davies, F., Cook, G. et al., A phase 2 study of SRT501 (resveratrol) with bortezomib for patients with relapsed and or refractory multiple myeloma. Br. J. Haematol. 2013, 160, 714-717.
    • (2013) Br. J. Haematol. , vol.160 , pp. 714-717
    • Popat, R.1    Plesner, T.2    Davies, F.3    Cook, G.4
  • 46
    • 80052910300 scopus 로고    scopus 로고
    • Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients
    • Brasnyo, P., Molnar, G. A., Mohas, M., Marko, L. et al., Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients. Br. J. Nutr. 2011, 106, 383-389.
    • (2011) Br. J. Nutr. , vol.106 , pp. 383-389
    • Brasnyo, P.1    Molnar, G.A.2    Mohas, M.3    Marko, L.4
  • 47
    • 84899550705 scopus 로고    scopus 로고
    • Effects of resveratrol in patients with type 2 diabetes mellitus on skeletal muscle SIRT1 expression and energy expenditure
    • Goh, K. P., Lee, H. Y., Lau, D. P., Supaat, W. et al., Effects of resveratrol in patients with type 2 diabetes mellitus on skeletal muscle SIRT1 expression and energy expenditure. Int. J. Sport Nutr. Exerc. Metab. 2014, 24, 2-13.
    • (2014) Int. J. Sport Nutr. Exerc. Metab. , vol.24 , pp. 2-13
    • Goh, K.P.1    Lee, H.Y.2    Lau, D.P.3    Supaat, W.4
  • 48
  • 50
    • 77949323966 scopus 로고    scopus 로고
    • Building comparative efficacy and tolerability into the FDA approval process
    • O'Connor, A. B., Building comparative efficacy and tolerability into the FDA approval process. J. Am. Med. Assoc. 2010, 303, 979-980.
    • (2010) J. Am. Med. Assoc. , vol.303 , pp. 979-980
    • O'Connor, A.B.1
  • 51
    • 0035850403 scopus 로고    scopus 로고
    • Effects of exercise on glycemic control and body mass in type 2 diabetes mellitus: a meta-analysis of controlled clinical trials
    • Boule, N. G., Haddad, E., Kenny, G. P., Wells, G. A. et al., Effects of exercise on glycemic control and body mass in type 2 diabetes mellitus: a meta-analysis of controlled clinical trials. J. Am. Med. Assoc. 2001, 286, 1218-1227.
    • (2001) J. Am. Med. Assoc. , vol.286 , pp. 1218-1227
    • Boule, N.G.1    Haddad, E.2    Kenny, G.P.3    Wells, G.A.4
  • 52
    • 79960202841 scopus 로고    scopus 로고
    • Type 2 diabetes across generations: from pathophysiology to prevention and management
    • Nolan, C. J., Damm, P., Prentki, M., Type 2 diabetes across generations: from pathophysiology to prevention and management. Lancet 2011, 378, 169-181.
    • (2011) Lancet , vol.378 , pp. 169-181
    • Nolan, C.J.1    Damm, P.2    Prentki, M.3
  • 53
    • 84908889125 scopus 로고    scopus 로고
    • Resveratrol promotes foot ulcer size reduction in type 2 diabetes patients
    • Bashmakov, Y. K., Assaad-Khalil, S. H., Abou Seif, M., Udumyan, R. et al., Resveratrol promotes foot ulcer size reduction in type 2 diabetes patients. ISRN Endocrinol. 2014, 2014, 816307.
    • (2014) ISRN Endocrinol. , vol.2014 , pp. 816307
    • Bashmakov, Y.K.1    Assaad-Khalil, S.H.2    Abou Seif, M.3    Udumyan, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.