Flies without trehalose

Journal of Biological Chemistry

Volumn 290, Issue 2, 2015, Pages 1244-1255

  Matsuda, Hiroko ^a,c   Yamada, Takayuki ^a   Yoshida, Miki ^a,b   Nishimura, Takashi ^a,b  

^a RIKEN Center for Biosystems Dynamics Research   (Japan)

^b NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^c TOKYO UNIVERSITY OF MARINE SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGY; BODY FLUIDS; DEFECTS; GLUCOSE; METABOLISM; NUTRITION; PHYSIOLOGY;

CENTRAL NERVOUS SYSTEMS; ENVIRONMENTAL CHANGE; GROWTH DEFECTS; LIVING ORGANISMS; LOCAL DEFECTS; LOW PROTEIN DIET; NUTRIENT AVAILABILITY; PHYSIOLOGICAL ROLES;

BLOOD;

TREHALOSE; GLUCOSE; GLUCOSYLTRANSFERASE; TREHALOSE SYNTHASE;

ADAPTIVE BEHAVIOR; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHROPOD LARVA; ARTICLE; BODY FAT; CARBOHYDRATE METABOLISM; CARBOHYDRATE SYNTHESIS; CONTROLLED STUDY; DIETARY INTAKE; DROSOPHILA; HOMEOSTASIS; INSECT DEVELOPMENT; LARVAL DEVELOPMENT; MUTANT; NONHUMAN; NUTRIENT AVAILABILITY; PHENOTYPE; STARVATION; STRESS; ANIMAL; ENZYMOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; LARVA; METABOLISM; MUTATION; PROTEIN RESTRICTION;

ANIMALIA; HEXAPODA; MAMMALIA;

ANIMALS; DIET, PROTEIN-RESTRICTED; DROSOPHILA; GLUCOSE; GLUCOSYLTRANSFERASES; LARVA; MUTATION; TREHALOSE;

EID: 84920973950     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.619411     Document Type: Article

References (35)

1. Saltiel, A. R., and Kahn, C. R. (2001) Insulin signaling and the regulation of glucose and lipid metabolism. Nature 414, 799-806
2. Becker, A., Schlöder, P., Steele, J. E., and Wegener, G. (1996) The regulation of trehalose metabolism in insects. Experientia 52, 433-439
3. Elbein, A. D., Pan, Y. T., Pastuszak, I., and Carroll, D. (2003) New insights on trehalose: a multifunctional molecule. Glycobiology 13, 17R-27R
4. Crowe, J. H., Carpenter, J. F., and Crowe, L. M. (1998) The role of vitrification in anhydrobiosis. Annu. Rev. Physiol. 60, 73-103
5. Wyatt, G. R., and Kalf, G. F. (1957) The chemistry of insect hemolymph. Trehalose and other carbohydrate. J. Gen. Physiol. 40, 833-847
6. Candy, D. J., and Kilby, B. A. (1959) Site and mode of trehalose biosynthesis in the locust. Nature 183, 1594-1595
7. Murphy, T. A., and Wyatt, G. R. (1965) The enzymes of glycogen and trehalose synthesis in silk moth fat body. J. Biol. Chem. 240, 1500-1508
8. Edgar, B. A. (2006) How flies get their size: genetics meets physiology. Nat. Rev. Genet. 7, 907-916
9. Hietakangas, V., and Cohen, S. M. (2009) Regulation of tissue growth through nutrient sensing. Annu. Rev. Genet. 43, 389-410
10. Rulifson, E. J., Kim, S. K., and Nusse, R. (2002) Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes. Science 296, 1118-1120
11. Kim, S. K., and Rulifson, E. J. (2004) Conserved mechanisms of glucose sensing and regulation by Drosophila corpora cardiaca cells. Nature 431, 316-320
12. Grönke, S., Müller, G., Hirsch, J., Fellert, S., Andreou, A., Haase, T., Jäckle, H., and Kühnlein, R. P. (2007) Dual lipolytic control of body fat storage and mobilization in Drosophila. PLoS Biol. 5, e137
13. Bharucha, K. N., Tarr, P., and Zipursky, S. L. (2008) A glucagon-like endocrine pathway in Drosophila modulates both lipid and carbohydrate homeostasis. J. Exp. Biol. 211, 3103-3110
14. Okamoto, N., Nakamori, R., Murai, T., Yamauchi, Y., Masuda, A., Nishimura, T. (2013) A secreted decoy of InR antagonizes insulin/IGF signaling to restrict body growth in Drosophila. Genes Dev. 27, 87-97
15. Okamoto, N., Nishimori, Y., Nishimura, T. (2012) Conserved role for the Dachshund protein with Drosophila Pax6 homolog Eyeless in insulin expression. Proc. Natl. Acad. Sci. U.S.A. 109, 2406-2411
16. Wirtz-Peitz, F., Nishimura, T., and Knoblich, J. A. (2008) Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization. Cell 135, 161-173
17. An, P. N., Yamaguchi, M., Bamba, T., and Fukusaki, E. (2014) Metabolome analysis of Drosophila melanogaster during embryogenesis. PLoS ONE 9, e99519
18. Tennessen, J. M., Bertagnolli, N. M., Evans, J., Sieber, M. H., Cox, J., and Thummel, C. S. (2014) Coordinated metabolic transitions during Drosophila embryogenesis and the onset of aerobic glycolysis. G3 4, 839-850
19. Kikawada, T., Saito, A., Kanamori, Y., Nakahara, Y., Iwata, K., Tanaka, D., Watanabe, M., and Okuda, T. (2007) Trehalose transporter 1, a facilitated and high-capacity trehalose transporter, allows exogenous trehalose uptake into cells. Proc. Natl. Acad. Sci. U.S.A. 104, 11585-11590
20. Chen, Q., Ma, E., Behar, K. L., Xu, T., and Haddad, G. G. (2002) Role of trehalose phosphate synthase in anoxia tolerance and development in Drosophila melanogaster. J. Biol. Chem. 277, 3274-3279
21. Ikeya, T., Galic, M., Belawat, P., Nairz, K., and Hafen, E. (2002) Nutrientdependent expression of insulin-like peptides from neuroendocrine cells in the CNS contributes to growth regulation in Drosophila. Curr. Biol. 12, 1293-1300
22. Havula, E., and Hietakangas, V. (2012) Glucose sensing by ChREBP/ MondoA-Mlx transcription factors. Semin. Cell Dev. Biol. 23, 640-647
23. Scott, R. C., Schuldiner, O., and Neufeld, T. P. (2004) Role and regulation of starvation-induced autophagy in the Drosophila fat body. Dev. Cell 7, 167-178
24. Honegger, B., Galic, M., Köhler, K., Wittwer, F., Brogiolo, W., Hafen, E., and Stocker, H. (2008) Imp-L2, a putative homolog of vertebrate IGFbinding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance. J. Biol. 7, 10
25. Palanker, L., Tennessen, J. M., Lam, G., and Thummel, C. S. (2009) Drosophila HNF4 regulates lipid mobilization and β-oxidation. Cell Metab. 9, 228-239
26. Gutierrez, E., Wiggins, D., Fielding, B., and Gould, A. P. (2007) Specialized hepatocyte-like cells regulate Drosophila lipid metabolism. Nature 445, 275-280
27. Ruaud, A. F., Lam, G., and Thummel, C. S. (2011) The Drosophila NR4A nuclear receptor DHR38 regulates carbohydrate metabolism and glycogen storage. Mol. Endocrinol. 25, 83-91
28. Zirin, J., Nieuwenhuis, J., and Perrimon, N. (2013) Role of autophagy in glycogen breakdown and its relevance to chloroquine myopathy. PLoS Biol. 11, e1001708
29. Géminard, C., Rulifson, E. J., and Léopold, P. (2009) Remote control of insulin secretion by fat cells in Drosophila. Cell Metab. 10, 199-207
30. Rajan, A., and Perrimon, N. (2012) Drosophila cytokine unpaired 2 regulates physiological homeostasis by remotely controlling insulin secretion. Cell 151, 123-137
31. Tennessen, J. M., Baker, K. D., Lam, G., Evans, J., and Thummel, C. S. (2011) The Drosophila estrogen-related receptor directs a metabolic switch that supports developmental growth. Cell Metab. 13, 139-148
32. McNabb, S. L., Baker, J. D., Agapite, J., Steller, H., Riddiford, L. M., and Truman, J. W. (1997) Disruption of a behavioral sequence by targeted death of peptidergic neurons in Drosophila. Neuron 19, 813-823
33. Davis, M. M., O'Keefe, S. L., Primrose, D. A., and Hodgetts, R. B. (2007) A neuropeptide hormone cascade controls the precise onset of post-eclosion cuticular tanning in Drosophila melanogaster. Development 134, 4395-4404
34. Havula, E., Teesalu, M., Hyötyläinen, T., Seppälä, H., Hasygar, K., Auvinen, P., Orešič, M., Sandmann, T., and Hietakangas, V. (2013) Mondo/ ChREBP-Mlx-regulated transcriptional network is essential for dietary sugar tolerance in Drosophila. PLoS Genet. 9, e1003438
35. Muller, Y. L., Hanson, R. L., Knowler, W. C., Fleming, J., Goswami, J., Huang, K., Traurig, M., Sutherland, J., Wiedrich, C., Wiedrich, K., Mahkee, D., Ossowski, V., Kobes, S., Bogardus, C., and Baier, L. J. (2013) Identification of genetic variation that determines human trehalase activity and its association with type 2 diabetes. Hum Genet. 132, 697-707