Effects of propylthiouracil-induced hypothyroidism on nonalcoholic fatty liver disease in rats fed a high-fat and high-cholesterol diet

Pakistan Veterinary Journal

Volumn 35, Issue 1, 2015, Pages 1-6

  Yang, Wei ^a,b   Wu, Dian Jun ^b   Zhang, Ren He ^a   Deng, Qing Hua ^a   Ding, Hong Yan ^a   Tian, Yu ^a   Zhang, Min ^a   Liu, Guo Wen ^a   Wang, Zhe ^a   Li, Xiao Bing ^a   Li, Xin Wei ^a  

^a JILIN UNIVERSITY   (China)

^b HEILONGJIANG BAYI AGRICULTURAL UNIVERSITY   (China)

Author keywords

High fat and high cholesterol diet; Hypothyroidism; Nonalcoholic fatty liver disease; Propylthiouracil

Indexed keywords

RATTUS; RATTUS NORVEGICUS;

EID: 84920866052     PISSN: 02538318     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Atawodi SE, DU Iliemene and E Onyike, 2014. In vivo antioxidant effect of methanolic extract of afzelia africana seed on carbon tetrachloride-induced acute and chronic oxidative injury in rats. Int J Agric Biol, 16: 597-602.
2. Aydemir S, Y Ustundag, T Bayraktaroglu, IO Tekin, I Peksoy and AU Unal, 2005. Fulminant hepatic failure associated with propylthiouracil: A case report with treatment emphasis on the use of plasmapheresis. J Clin Apheresis, 20: 235-238.
3. Bahn RS, HS Burch, DS Cooper, JR Garber, CM Greenlee, IL Klein, P Laurberg, IR McDougall, SA Rivkees, D Ross, JA Sosa and MN Stan, 2009. The role of propylthiouracil in the management of graves' disease in adults: report of a meeting jointly sponsored by the American Thyroid Association and the Food and Drug Administration. Thyroid, 19: 673-674.
4. Bugianesi E, AJ McCullough and G Marchesini, 2005. Insulin resistance: a metabolic pathway to chronic liver disease. Hepatology, 42: 987-1000.
5. Carmichael FJ, H Orrego, V Saldivia and Y Israel, 1993. Effect of propylthiouracil on the ethanol-induced increase in liver oxygen consumption in awake rats. Hepatology, 18: 415-421.
6. Diaz-Espineira MM, S Galac, JA Mol, A Rijnberk and HS Kooistra, 2008. Thyrotropin-releasing hormone-induced growth hormone secretion in dogs with primary hypothyroidism. Domest Anim Endocrinol, 34: 176-181.
7. Fuchs M and EF Stange, 2001. Cholesterol and cholestasis: a lesson from the Mdr2 (-/-) mouse. J Hepatol, 34: 339-341.
8. Fujita K, Y Nozaki, K Wada, M Yoneda, Y Fujimoto, M Fujitake, H Endo, H Takahashi, M Inamori, N Kobayashi, H Kirikoshi, K Kubota, S Saito and A Nakajima, 2009. Dysfunctional very-low-density lipoprotein synthesis and release is a key factor in nonalcoholic steatohepatitis pathogenesis. Hepatology, 50: 772-780.
9. Hackmon R, M Blichowski and G Koren, 2012. The safety of methimazole and propylthiouracil in pregnancy: a systematic review. J Obstet Gynaecol Ca, 34: 1077-1086.
10. Hsieh FC, CL Lee, CY Chai, WT Chen, YC Lu and CS Wu, 2013. Oral administration of Lactobacillus reuteri GMNL-263 improves insulin resistance and ameliorates hepatic steatosis in high fructose-fed rats. Nutr Metab, 10: 35.
11. Hu FB, RM van Dam and S Liu, 2001. Diet and risk of Type II diabetes: the role of types of fat and carbohydrate. Diabetologia, 44: 805-817.
12. Lee S, H Joo, CT Kim, IH Kim and Y Kim, 2012. High hydrostatic pressure extract of garlic increases the HDL cholesterol level via up-regulation of apolipoprotein A-I gene expression in rats fed a high-fat diet. Lipids Health Dis, 11: 77.
13. Marchesini G, E Bugianesi, G Forlani, F Cerrelli, M Lenzi, R Manini, S Natale, E Vanni, N Villanova, N Melchionda and M Rizzetto, 2003. Nonalcoholic fatty liver, steatohepatitis and the metabolic syndrome. Hepatology, 37: 917-923.
14. Matsuzawa N, T Takamura, S Kurita, H Misu, T Ota, H Ando, M Yokoyama, M Honda, Y Zen, Y Nakanuma, K Miyamoto and S Kaneko, 2007. Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet. Hepatology, 46:1392-1403.
15. Moon BC, A Hernandez-Ono, B Stiles, H Wu and HN Ginsberg, 2012. Apolipoprotein B secretion is regulated by hepatic triglyceride, and not insulin, in a model of increased hepatic insulin signaling. Arterioscl Throm Vas, 32: 236-246.
16. Musso G, R Gambino, F De Michieli, M Cassader, M Rizzetto, M Durazzo, E Faga, B Silli and G Pagano, 2003. Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis. Hepatology, 37: 909-916.
17. Musso G, M Cassader, F De Michieli, F Rosina, F Orlandi and R Gambino, 2012. Nonalcoholic steatohepatitis versus steatosis: adipose tissue insulin resistance and dysfunctional response to fat ingestion predict liver injury and altered glucose and lipoprotein metabolism. Hepatology, 56: 933-942.
18. Nakamura H, JY Noh, K Itoh, S Fukata, A Miyauchi and N Hamada, 2007. Comparison of methimazole and propylthiouracil in patients with hyperthyroidism caused by Graves' disease. J Clin Endocr Metab, 92: 2157-2162.
19. Ness GC, LC Pendleton, YC Li and JY Chiang, 1990. Effect of thyroid hormone on hepatic cholesterol 7 alpha hydroxylase, LDL receptor, HMG-CoA reductase, farnesyl pyrophosphate synthetase and apolipoprotein A-I mRNA levels in hypophysectomized rats. Biochem Bioph Res Co, 172: 1150-1156.
20. Nobili V, G Svegliati-Baroni, A Alisi, L Miele, L Valenti and P Vajro, 2013. A 360-degree overview of paediatric NAFLD: recent insights. J Hepatol, 58: 1218-1229.
21. Pagadala MR, CO Zein, S Dasarathy, LM Yerian, R Lopez and AJ McCullough, 2012. Prevalence of hypothyroidism in nonalcoholic fatty liver disease. Digest Dis Sci, 57: 528-534.
22. Reeves PG, FH Nielsen and GC Fahey, 1993. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr, 123: 1939-1951.
23. Schmitz G and T Langmann, 2001. Structure, function and regulation of the ABC1 gene product. Curr Opin Lipidol, 12: 129-140.
24. Sert A, O Pirgon, E Aypar, H Yilmaz and D Odabas, 2013. Subclinical hypothyroidism as a risk factor for the development of cardiovascular disease in obese adolescents with nonalcoholic fatty liver disease. Pediatr Cardiol, 34: 1166-1174.
25. Shindo N, T Fujisawa, K Sugimoto, K Nojima, A Oze-Fukai, Y Yoshikawa, X Wang, O Yasuda, H Ikegami and H Rakugi, 2010. Involvement of microsomal triglyceride transfer protein in nonalcoholic steatohepatitis in novel spontaneous mouse model. J Hepatol, 52: 903-912.
26. Silva D, C Lizama, V Tapia and RD Moreno, 2011. Propylthiouracilinduced hypothyroidism delays apoptosis during the first wave of spermatogenesis. Biol Res, 44: 181-188.
27. Tietge UJ, A Bakillah, C Maugeais, K Tsukamoto, M Hussain and DJ Rader, 1999. Hepatic overexpression of microsomal triglyceride transfer protein (MTP) results in increased in vivo secretion of VLDL triglycerides and apolipoprotein B. J Lipid Res, 40: 2134-2139.
28. Verma S, D Jensen, J Hart and SR Mohanty, 2013. Predictive value of ALT levels for non-alcoholic steatohepatitis (NASH) and advanced fibrosis in non-alcoholic fatty liver disease (NAFLD). Liver Inter, 33: 1398-1405.
29. Wilcox LJ, PH Barrett and MW Huff, 1999. Differential regulation of apolipoprotein B secretion from HepG2 cells by two HMG-CoA reductase inhibitors, atorvastatin and simvastatin. J Lipid Res, 40:1078-1089.
30. Xu L, H Ma, M Miao and YM Li, 2012. Impact of subclinical hypothyroidism on the development of non-alcoholic fatty liver disease: A prospective case-control study. J Hepatol, 57: 1153-1154.
31. Yuan L, J Wang and WC Shen, 2008. Reversible lipidization of somatostatin analogues for the liver targeting. Eur J Pharm Biopharm, 70: 615-620.