메뉴 건너뛰기




Volumn 37, Issue 1, 2015, Pages 20-38

Immunotherapy: An evolving paradigm in the treatment of advanced cervical cancer

Author keywords

Cervical cancer; Checkpoint inhibitor; Chimeric T cell receptor antigen; Human papillomavirus; Immunotherapy; Therapeutic vaccine

Indexed keywords

ALPHA2B INTERFERON; AMOLIMOGENE BEPIPLASMID; BACTERIAL VACCINE; BACTERIAL VECTOR; BCG VACCINE; BISPECIFIC ANTIBODY; BISPECIFIC T CELL ENGAGER ANTIBODY; BLINATUMOMAB; CANCER VACCINE; CARBOPLATIN; CORTICOSTEROID; DENDRITIC CELL VACCINE; DNA VACCINE; NUCLEIC ACID; PACLITAXEL; PEPTIDE VACCINE; PLACEBO; RECOMBINANT INTERLEUKIN 2; RITUXIMAB; RNA VACCINE; SIPULEUCEL T; SMALLPOX VACCINE; T LYMPHOCYTE RECEPTOR; TOCILIZUMAB; TRASTUZUMAB; TUMOR CELL VACCINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VACCINIA VACCINE; VIRUS VECTOR; WART VIRUS VACCINE; IMMUNOLOGIC FACTOR;

EID: 84920855444     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/j.clinthera.2014.11.010     Document Type: Review
Times cited : (44)

References (90)
  • 3
    • 84904052981 scopus 로고    scopus 로고
    • Chemotherapy in the treatment of metastatic, persistent, and recurrent cervical cancer
    • Eskander RN, Tewari KS. Chemotherapy in the treatment of metastatic, persistent, and recurrent cervical cancer. Curr Opin Obstet Gynecol. 2014;26:314-321.
    • (2014) Curr Opin Obstet Gynecol , vol.26 , pp. 314-321
    • Eskander, R.N.1    Tewari, K.S.2
  • 4
    • 84906815244 scopus 로고    scopus 로고
    • Evidence-based therapy for recurrent cervical cancer
    • Monk BJ, Tewari KS. Evidence-based therapy for recurrent cervical cancer. J Clin Oncol. 2014;32:2687-2690.
    • (2014) J Clin Oncol , vol.32 , pp. 2687-2690
    • Monk, B.J.1    Tewari, K.S.2
  • 5
    • 0019408691 scopus 로고
    • Cis-platinum in treatment of advanced or recurrent squamous cell carcinoma of the cervix: A phase II study of the Gynecologic Oncology Group
    • Thigpen T, Shingleton H, Homesley H, et al. Cis-platinum in treatment of advanced or recurrent squamous cell carcinoma of the cervix: a phase II study of the Gynecologic Oncology Group. Cancer. 1981;48:899-903.
    • (1981) Cancer , vol.48 , pp. 899-903
    • Thigpen, T.1    Shingleton, H.2    Homesley, H.3
  • 6
    • 0024747607 scopus 로고
    • A randomized comparative trial of carboplatin and iproplatin in advanced squamous carcinoma of the uterine cervix: A Gynecologic Oncology Group study
    • McGuire WP 3rd, Arseneau J, Blessing JA, et al. A randomized comparative trial of carboplatin and iproplatin in advanced squamous carcinoma of the uterine cervix: a Gynecologic Oncology Group study. J Clin Oncol. 1989;7:1462-1468.
    • (1989) J Clin Oncol , vol.7 , pp. 1462-1468
    • McGuire 3rd, W.P.1    Arseneau, J.2    Blessing, J.A.3
  • 7
    • 0037486920 scopus 로고    scopus 로고
    • Phase II evaluation of oxaliplatin in previously treated squamous cell carcinoma of the cervix: A gynecologic oncology group study
    • Fracasso PM, Blessing JA, Wolf J, et al. Phase II evaluation of oxaliplatin in previously treated squamous cell carcinoma of the cervix: a gynecologic oncology group study. Gynecol Oncol. 2003;90:177-180.
    • (2003) Gynecol Oncol , vol.90 , pp. 177-180
    • Fracasso, P.M.1    Blessing, J.A.2    Wolf, J.3
  • 8
    • 0029041394 scopus 로고
    • Phase II trial of mitomycin-C in squamous cell carcinoma of the uterine cervix: A Gynecologic Oncology Group study
    • Thigpen T, Blessing JA, Gallup DG, et al. Phase II trial of mitomycin-C in squamous cell carcinoma of the uterine cervix: a Gynecologic Oncology Group study. Gynecol Oncol. 1995;57:376-379.
    • (1995) Gynecol Oncol , vol.57 , pp. 376-379
    • Thigpen, T.1    Blessing, J.A.2    Gallup, D.G.3
  • 9
    • 0024450677 scopus 로고
    • Phase II study of ifosfamide and mesna in patients with previously-treated carcinoma of the cervix: A Gynecologic Oncology Group study
    • Sutton GP, Blessing JA, Adcock L, et al. Phase II study of ifosfamide and mesna in patients with previously-treated carcinoma of the cervix: a Gynecologic Oncology Group study. Invest New Drugs. 1989;7:341-343.
    • (1989) Invest New Drugs , vol.7 , pp. 341-343
    • Sutton, G.P.1    Blessing, J.A.2    Adcock, L.3
  • 10
    • 0032168956 scopus 로고    scopus 로고
    • A phase II trial of CPT-11 in recurrent squamous carcinoma of the cervix: A Gynecologic Oncology Group study
    • Look KY, Blessing JA, Levenback C, et al. A phase II trial of CPT-11 in recurrent squamous carcinoma of the cervix: a Gynecologic Oncology Group study. Gynecol Oncol. 1998;70:334-338.
    • (1998) Gynecol Oncol , vol.70 , pp. 334-338
    • Look, K.Y.1    Blessing, J.A.2    Levenback, C.3
  • 11
    • 0033959650 scopus 로고    scopus 로고
    • Evaluation of gemcitabine in patients with squamous cell carcinoma of the cervix: A Phase II study of the gynecologic oncology group
    • Schilder RJ, Blessing JA, Morgan M, et al. Evaluation of gemcitabine in patients with squamous cell carcinoma of the cervix: a Phase II study of the gynecologic oncology group. Gynecol Oncol. 2000;76:204-207.
    • (2000) Gynecol Oncol , vol.76 , pp. 204-207
    • Schilder, R.J.1    Blessing, J.A.2    Morgan, M.3
  • 12
    • 0034089496 scopus 로고    scopus 로고
    • Topotecan in squamous cell carcinoma of the cervix: A Phase II study of the Gynecologic Oncology Group
    • Bookman MA, Blessing JA, Hanjani P, et al. Topotecan in squamous cell carcinoma of the cervix: a Phase II study of the Gynecologic Oncology Group. Gynecol Oncol. 2000;77:446-449.
    • (2000) Gynecol Oncol , vol.77 , pp. 446-449
    • Bookman, M.A.1    Blessing, J.A.2    Hanjani, P.3
  • 13
    • 0035281646 scopus 로고    scopus 로고
    • Paclitaxel, an active agent in nonsquamous carcinomas of the uterine cervix: A Gynecologic Oncology Group Study
    • Curtin JP, Blessing JA, Webster KD, et al. Paclitaxel, an active agent in nonsquamous carcinomas of the uterine cervix: a Gynecologic Oncology Group Study. J Clin Oncol. 2001;19:1275-1278.
    • (2001) J Clin Oncol , vol.19 , pp. 1275-1278
    • Curtin, J.P.1    Blessing, J.A.2    Webster, K.D.3
  • 14
    • 0029865737 scopus 로고    scopus 로고
    • Paclitaxel has moderate activity in squamous cervix cancer: A Gynecologic Oncology Group study
    • McGuire WP, Blessing JA, Moore D, et al. Paclitaxel has moderate activity in squamous cervix cancer: a Gynecologic Oncology Group study. J Clin Oncol. 1996;14:792-795.
    • (1996) J Clin Oncol , vol.14 , pp. 792-795
    • McGuire, W.P.1    Blessing, J.A.2    Moore, D.3
  • 15
    • 34548437625 scopus 로고    scopus 로고
    • Phase II clinical trial of docetaxel in refractory squamous cell carcinoma of the cervix: A Gynecologic Oncology Group Study
    • Garcia AA, Blessing JA, Vaccarello L, Roman LD. Phase II clinical trial of docetaxel in refractory squamous cell carcinoma of the cervix: a Gynecologic Oncology Group Study. Am J Clin Oncol. 2007;30:428-431.
    • (2007) Am J Clin Oncol , vol.30 , pp. 428-431
    • Garcia, A.A.1    Blessing, J.A.2    Vaccarello, L.3    Roman, L.D.4
  • 16
    • 10044278053 scopus 로고    scopus 로고
    • Evaluation of vinorelbine in persistent or recurrent nonsquamous carcinoma of the cervix: A Gynecologic Oncology Group Study
    • Muggia FM, Blessing JA, Waggoner S, et al. Evaluation of vinorelbine in persistent or recurrent nonsquamous carcinoma of the cervix: a Gynecologic Oncology Group Study. Gynecol Oncol. 2005;96:108-111.
    • (2005) Gynecol Oncol , vol.96 , pp. 108-111
    • Muggia, F.M.1    Blessing, J.A.2    Waggoner, S.3
  • 17
    • 0036534291 scopus 로고    scopus 로고
    • Randomized trial of cisplatin and ifosfamide with or without bleomycin in squamous carcinoma of the cervix: A gynecologic oncology group study
    • Bloss JD, Blessing JA, Behrens BC, et al. Randomized trial of cisplatin and ifosfamide with or without bleomycin in squamous carcinoma of the cervix: a gynecologic oncology group study. J Clin Oncol. 2002;20:1832-1837.
    • (2002) J Clin Oncol , vol.20 , pp. 1832-1837
    • Bloss, J.D.1    Blessing, J.A.2    Behrens, B.C.3
  • 18
    • 23044495279 scopus 로고    scopus 로고
    • Randomized phase III trial of cisplatin with or without topotecan in carcinoma of the uterine cervix: A Gynecologic Oncology Group Study
    • Long HJ III, Bundy BN, Grendys EC Jr., et al. Randomized phase III trial of cisplatin with or without topotecan in carcinoma of the uterine cervix: a Gynecologic Oncology Group Study. J Clin Oncol. 2005;23:4626-4633.
    • (2005) J Clin Oncol , vol.23 , pp. 4626-4633
    • Long, H.J.1    Bundy, B.N.2    Grendys, E.C.3
  • 19
    • 70350433286 scopus 로고    scopus 로고
    • Phase III trial of four cisplatin-containing doublet combinations in stage IVB, recurrent, or persistent cervical carcinoma: A Gynecologic Oncology Group study
    • Monk BJ, Sill MW, McMeekin DS, et al. Phase III trial of four cisplatin-containing doublet combinations in stage IVB, recurrent, or persistent cervical carcinoma: a Gynecologic Oncology Group study. J Clin Oncol. 2009;27:4649-4655.
    • (2009) J Clin Oncol , vol.27 , pp. 4649-4655
    • Monk, B.J.1    Sill, M.W.2    McMeekin, D.S.3
  • 20
    • 4143135504 scopus 로고    scopus 로고
    • Phase III study of cisplatin with or without paclitaxel in stage IVB, recurrent, or persistent squamous cell carcinoma of the cervix: A gynecologic oncology group study
    • Moore DH, Blessing JA, McQuellon RP, et al. Phase III study of cisplatin with or without paclitaxel in stage IVB, recurrent, or persistent squamous cell carcinoma of the cervix: a gynecologic oncology group study. J Clin Oncol. 2004;22:3113-3119.
    • (2004) J Clin Oncol , vol.22 , pp. 3113-3119
    • Moore, D.H.1    Blessing, J.A.2    McQuellon, R.P.3
  • 21
    • 0031023552 scopus 로고    scopus 로고
    • Randomized trial of cisplatin versus cisplatin plus mitolactol versus cisplatin plus ifosfamide in advanced squamous carcinoma of the cervix: A Gynecologic Oncology Group study
    • Omura GA, Blessing JA, Vaccarello L, et al. Randomized trial of cisplatin versus cisplatin plus mitolactol versus cisplatin plus ifosfamide in advanced squamous carcinoma of the cervix: a Gynecologic Oncology Group study. J Clin Oncol. 1997;15:165-171.
    • (1997) J Clin Oncol , vol.15 , pp. 165-171
    • Omura, G.A.1    Blessing, J.A.2    Vaccarello, L.3
  • 22
    • 84894207820 scopus 로고    scopus 로고
    • Improved survival with bevacizumab in advanced cervical cancer
    • Tewari KS, Sill MW, Long HJ III, et al. Improved survival with bevacizumab in advanced cervical cancer. N Engl J Med. 2014;370:734-743.
    • (2014) N Engl J Med , vol.370 , pp. 734-743
    • Tewari, K.S.1    Sill, M.W.2    Long, H.J.3
  • 23
    • 84920826970 scopus 로고    scopus 로고
    • Development of bevacizumab in advanced cervical cancer: Pharmacodynamic modeling, survival impact, and toxicology
    • In press
    • Eskander RN, Tewari KS. Development of bevacizumab in advanced cervical cancer: pharmacodynamic modeling, survival impact, and toxicology. Future Med. In press.
    • Future Med
    • Eskander, R.N.1    Tewari, K.S.2
  • 24
    • 84910029185 scopus 로고    scopus 로고
    • Targeting angiogenesis in advanced cervical cancer
    • KS
    • Eskander RT, KS. Targeting angiogenesis in advanced cervical cancer. Ther Adv Med Oncol. 2014;6:280-292.
    • (2014) Ther Adv Med Oncol , vol.6 , pp. 280-292
    • Eskander, R.T.1
  • 25
    • 84904670005 scopus 로고    scopus 로고
    • Beyond angiogenesis blockade: Targeted therapy for advanced cervical cancer
    • Eskander RN, Tewari KS. Beyond angiogenesis blockade: targeted therapy for advanced cervical cancer. J. Gynecol Oncol. 2014;25:249-259.
    • (2014) J. Gynecol Oncol , vol.25 , pp. 249-259
    • Eskander, R.N.1    Tewari, K.S.2
  • 26
    • 84908311912 scopus 로고    scopus 로고
    • Clinical commentary: Medical ethics and the ramifications of equipoise in clinical research: Is a confirmatory trial using a non-bevacizumab containing arm feasible in patients with recurrent cervical cancer?
    • Krill LS, Adelson JW, Randall LM, Bristow RE. Clinical commentary: medical ethics and the ramifications of equipoise in clinical research: is a confirmatory trial using a non-bevacizumab containing arm feasible in patients with recurrent cervical cancer? Gynecol Oncol. 2014;134:447-449.
    • (2014) Gynecol Oncol , vol.134 , pp. 447-449
    • Krill, L.S.1    Adelson, J.W.2    Randall, L.M.3    Bristow, R.E.4
  • 27
    • 66249140995 scopus 로고    scopus 로고
    • Persistence of highgrade cervical dysplasia and cervical cancer requires the continuous expression of the human papillomavirus type 16 E7 oncogene
    • Jabbar SF, Abrams L, Glick A, Lambert PF. Persistence of highgrade cervical dysplasia and cervical cancer requires the continuous expression of the human papillomavirus type 16 E7 oncogene. Cancer Res. 2009;69:4407-4414.
    • (2009) Cancer Res , vol.69 , pp. 4407-4414
    • Jabbar, S.F.1    Abrams, L.2    Glick, A.3    Lambert, P.F.4
  • 28
    • 0026548255 scopus 로고
    • Disruption of either the E1 or the E2 regulatory gene of human papillomavirus type 16 increases viral immortalization capacity
    • Romanczuk H, Howley PM. Disruption of either the E1 or the E2 regulatory gene of human papillomavirus type 16 increases viral immortalization capacity. Proc Natl Acad Sci U S A. 1992;89:3159-3163.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 3159-3163
    • Romanczuk, H.1    Howley, P.M.2
  • 29
    • 0026361232 scopus 로고
    • Cellular targets of the oncoproteins encoded by the cancer associated human papillomaviruses
    • Howley PM, Munger K, Romanczuk H, et al. Cellular targets of the oncoproteins encoded by the cancer associated human papillomaviruses. Princess Takamatsu Symp. 1991;22:239-248.
    • (1991) Princess Takamatsu Symp , vol.22 , pp. 239-248
    • Howley, P.M.1    Munger, K.2    Romanczuk, H.3
  • 30
    • 84255197842 scopus 로고    scopus 로고
    • Cancer immunotherapy comes of age
    • Mellman I, Coukos G, Dranoff G. Cancer immunotherapy comes of age. Nature. 2011;480:480-489.
    • (2011) Nature , vol.480 , pp. 480-489
    • Mellman, I.1    Coukos, G.2    Dranoff, G.3
  • 31
    • 0028081705 scopus 로고
    • Coley's toxins, tumor necrosis factor and cancer research: A historical perspective
    • Wiemann B, Starnes CO. Coley's toxins, tumor necrosis factor and cancer research: a historical perspective. Pharmacol Ther. 1994;64:529-564.
    • (1994) Pharmacol Ther , vol.64 , pp. 529-564
    • Wiemann, B.1    Starnes, C.O.2
  • 32
    • 0037383526 scopus 로고    scopus 로고
    • Cancer immunotherapy: The past, the present and the future
    • Parish CR. Cancer immunotherapy: the past, the present and the future. Immunol Cell Biol. 2003;81:106-113.
    • (2003) Immunol Cell Biol , vol.81 , pp. 106-113
    • Parish, C.R.1
  • 33
    • 77749270735 scopus 로고    scopus 로고
    • Immunotherapy for cervical cancer: Research status and clinical potential
    • Su JH, Wu A, Scotney E, et al. Immunotherapy for cervical cancer: research status and clinical potential. BioDrugs. 2010;24:109-129.
    • (2010) BioDrugs , vol.24 , pp. 109-129
    • Su, J.H.1    Wu, A.2    Scotney, E.3
  • 34
    • 50849136160 scopus 로고    scopus 로고
    • Listeria-based HPV-16 E7 vaccines limit autochthonous tumor growth in a transgenic mouse model for HPV-16 transformed tumors
    • Sewell DA, Pan ZK, Paterson Y. Listeria-based HPV-16 E7 vaccines limit autochthonous tumor growth in a transgenic mouse model for HPV-16 transformed tumors. Vaccine. 2008;26:5315-5320.
    • (2008) Vaccine , vol.26 , pp. 5315-5320
    • Sewell, D.A.1    Pan, Z.K.2    Paterson, Y.3
  • 35
    • 17444425389 scopus 로고    scopus 로고
    • Cellsurface display of E7 antigen from human papillomavirus type-16 in Lactococcus lactis and in Lactobacillus plantarum using a new cell-wall anchor from lactobacilli
    • Cortes-Perez NG, Azevedo V, Alcocer-Gonzalez JM, et al. Cellsurface display of E7 antigen from human papillomavirus type-16 in Lactococcus lactis and in Lactobacillus plantarum using a new cell-wall anchor from lactobacilli. J Drug Target. 2005;13:89-98.
    • (2005) J Drug Target , vol.13 , pp. 89-98
    • Cortes-Perez, N.G.1    Azevedo, V.2    Alcocer-Gonzalez, J.M.3
  • 37
    • 0028799266 scopus 로고
    • Regression of established tumors in mice mediated by the oral administration of a recombinant Listeria monocytogenes vaccine
    • Pan ZK, Ikonomidis G, Pardoll D, Paterson Y. Regression of established tumors in mice mediated by the oral administration of a recombinant Listeria monocytogenes vaccine. Cancer Res. 1995;55:4776-4779.
    • (1995) Cancer Res , vol.55 , pp. 4776-4779
    • Pan, Z.K.1    Ikonomidis, G.2    Pardoll, D.3    Paterson, Y.4
  • 38
    • 0029047262 scopus 로고
    • A recombinant Listeria monocytogenes vaccine expressing a model tumour antigen protects mice against lethal tumour cell challenge and causes regression of established tumours
    • Pan ZK, Ikonomidis G, Lazenby A, et al. A recombinant Listeria monocytogenes vaccine expressing a model tumour antigen protects mice against lethal tumour cell challenge and causes regression of established tumours. Nat Med. 1995;1:471-477.
    • (1995) Nat Med , vol.1 , pp. 471-477
    • Pan, Z.K.1    Ikonomidis, G.2    Lazenby, A.3
  • 39
    • 59349105912 scopus 로고    scopus 로고
    • Multiple effector mechanisms induced by recombinant Listeria monocytogenes anticancer immunotherapeutics
    • Wallecha A, Carroll KD, Maciag PC, et al. Multiple effector mechanisms induced by recombinant Listeria monocytogenes anticancer immunotherapeutics. Adv Appl Microbiol. 2009;66:1-27.
    • (2009) Adv Appl Microbiol , vol.66 , pp. 1-27
    • Wallecha, A.1    Carroll, K.D.2    Maciag, P.C.3
  • 40
    • 45849139670 scopus 로고    scopus 로고
    • Development of a Listeria monocytogenes based vaccine against prostate cancer
    • Shahabi V, Reyes-Reyes M, Wallecha A, et al. Development of a Listeria monocytogenes based vaccine against prostate cancer. Cancer Immunol Immunother. 2008;57:1301-1313.
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 1301-1313
    • Shahabi, V.1    Reyes-Reyes, M.2    Wallecha, A.3
  • 41
    • 67349153373 scopus 로고    scopus 로고
    • The first clinical use of a live-attenuated Listeria monocytogenes vaccine: A Phase I safety study of Lm-LLO-E7 in patients with advanced carcinoma of the cervix
    • Maciag PC, Radulovic S, Rothman J. The first clinical use of a live-attenuated Listeria monocytogenes vaccine: a Phase I safety study of Lm-LLO-E7 in patients with advanced carcinoma of the cervix. Vaccine. 2009;27:3975-3983.
    • (2009) Vaccine , vol.27 , pp. 3975-3983
    • Maciag, P.C.1    Radulovic, S.2    Rothman, J.3
  • 42
    • 84894674354 scopus 로고    scopus 로고
    • ADXS11-001 immunotherapy targeting HPV-E7: Preliminary survival data from a P2 study in Indian women with recurrent/refractory cervical cancer
    • Petit RG, Basu P. Advaxis Inc., Princeton, NJ; Chittaranjan National Cancer Institute, Kolkata, India. ADXS11-001 immunotherapy targeting HPV-E7: preliminary survival data from a P2 study in Indian women with recurrent/refractory cervical cancer. J Clin Oncol. 2013;31(Suppl): Abstract 5529.
    • (2013) J Clin Oncol , vol.31
    • Petit, R.G.1    Basu, P.2    Advaxis Inc., Princeton, NJ,3    Chittaranjan National Cancer Institute, Kolkata, India,4
  • 43
    • 84863258367 scopus 로고    scopus 로고
    • Lm-LLO-Based Immunotherapies and HPV-Associated Disease
    • Wallecha A, French C, Petit R, et al. Lm-LLO-Based Immunotherapies and HPV-Associated Disease. J Oncol. 2012;2012:542-851.
    • (2012) J Oncol , vol.2012 , pp. 542-851
    • Wallecha, A.1    French, C.2    Petit, R.3
  • 44
    • 84911932332 scopus 로고    scopus 로고
    • ADXS11-001 immunotherapy targeting HPV-E7: Final results from a phase 2 study in Indian women with recurrent cervical cancer
    • Basu P, Mehta AO, Jain MM, et al. ADXS11-001 immunotherapy targeting HPV-E7: final results from a phase 2 study in Indian women with recurrent cervical cancer. J Clin Oncol. 2014;32(Suppl 5): Abstract 5610.
    • (2014) J Clin Oncol , vol.32
    • Basu, P.1    Mehta, A.O.2    Jain, M.M.3
  • 45
    • 84920826969 scopus 로고    scopus 로고
    • A phase 2 study of liveattenuated listeria monocytogenes cancer immunotherapy (ADXS11-001) in the treatment of persistent or recurrent cancer of the cervix (GOG-0265)
    • Huh WK, Brady W, Moore KN, et al. A phase 2 study of liveattenuated listeria monocytogenes cancer immunotherapy (ADXS11-001) in the treatment of persistent or recurrent cancer of the cervix (GOG-0265). J Clin Oncol. 2014;32 (5 suppl): Abstract TPS5617.
    • (2014) J Clin Oncol , vol.32 , Issue.5
    • Huh, W.K.1    Brady, W.2    Moore, K.N.3
  • 46
    • 0036894973 scopus 로고    scopus 로고
    • Safety and immunogenicity of TA-HPV, a recombinant vaccinia virus expressing modified human papillomavirus (HPV)-16 and HPV- 18 E6 and E7 genes, in women with progressive cervical cancer
    • Kaufmann AM, Stern PL, Rankin EM, et al. Safety and immunogenicity of TA-HPV, a recombinant vaccinia virus expressing modified human papillomavirus (HPV)-16 and HPV- 18 E6 and E7 genes, in women with progressive cervical cancer. Clin Cancer Res. 2002;8:3676-3685.
    • (2002) Clin Cancer Res , vol.8 , pp. 3676-3685
    • Kaufmann, A.M.1    Stern, P.L.2    Rankin, E.M.3
  • 47
    • 15844365301 scopus 로고    scopus 로고
    • A recombinant vaccinia virus encoding human papillomavirus types 16 and 18, E6 and E7 proteins as immunotherapy for cervical cancer
    • Borysiewicz LK, Fiander A, Nimako M, et al. A recombinant vaccinia virus encoding human papillomavirus types 16 and 18, E6 and E7 proteins as immunotherapy for cervical cancer. Lancet. 1996;347:1523-1527.
    • (1996) Lancet , vol.347 , pp. 1523-1527
    • Borysiewicz, L.K.1    Fiander, A.2    Nimako, M.3
  • 48
    • 0027320440 scopus 로고
    • Vaccination with cytotoxic T lymphocyte epitopecontaining peptide protects against a tumor induced by human papillomavirus type 16-transformed cells
    • Feltkamp MC, Smits HL, Vierboom MP, et al. Vaccination with cytotoxic T lymphocyte epitopecontaining peptide protects against a tumor induced by human papillomavirus type 16-transformed cells. Eur J Immunol. 1993;23:2242-2249.
    • (1993) Eur J Immunol , vol.23 , pp. 2242-2249
    • Feltkamp, M.C.1    Smits, H.L.2    Vierboom, M.P.3
  • 49
    • 0033153564 scopus 로고    scopus 로고
    • Vaccination with HPV16 peptides of patients with advanced cervical carcinoma: Clinical evaluation of a phase I-II trial
    • van Driel WJ, Ressing ME, Kenter GG, et al. Vaccination with HPV16 peptides of patients with advanced cervical carcinoma: clinical evaluation of a phase I-II trial. Eur J Cancer. 1999;35:946-952.
    • (1999) Eur J Cancer , vol.35 , pp. 946-952
    • Van Driel, W.J.1    Ressing, M.E.2    Kenter, G.G.3
  • 50
    • 40549129230 scopus 로고    scopus 로고
    • Phase I immunotherapeutic trial with long peptides spanning the E6 and E7 sequences of high-risk human papillomavirus 16 in end-stage cervical cancer patients shows low toxicity and robust immunogenicity
    • Kenter GG, Welters MJ, Valentijn AR, et al. Phase I immunotherapeutic trial with long peptides spanning the E6 and E7 sequences of high-risk human papillomavirus 16 in end-stage cervical cancer patients shows low toxicity and robust immunogenicity. Clin Cancer Res. 2008;14:169-177.
    • (2008) Clin Cancer Res , vol.14 , pp. 169-177
    • Kenter, G.G.1    Welters, M.J.2    Valentijn, A.R.3
  • 51
    • 40549110815 scopus 로고    scopus 로고
    • Induction of tumor-specific CD4+ and CD8+ T-cell immunity in cervical cancer patients by a human papillomavirus type 16 E6 and E7 long peptides vaccine
    • Welters MJ, Kenter GG, Piersma SJ, et al. Induction of tumor-specific CD4+ and CD8+ T-cell immunity in cervical cancer patients by a human papillomavirus type 16 E6 and E7 long peptides vaccine. Clin Cancer Res. 2008;14:178-187.
    • (2008) Clin Cancer Res , vol.14 , pp. 178-187
    • Welters, M.J.1    Kenter, G.G.2    Piersma, S.J.3
  • 52
    • 34548127036 scopus 로고    scopus 로고
    • A phase II study of Hsp-7 (SGN-00101) in women with high-grade cervical intraepithelial neoplasia
    • Roman LD, Wilczynski S, Muderspach LI, et al. A phase II study of Hsp-7 (SGN-00101) in women with high-grade cervical intraepithelial neoplasia. Gynecol Oncol. 2007;106:558-566.
    • (2007) Gynecol Oncol , vol.106 , pp. 558-566
    • Roman, L.D.1    Wilczynski, S.2    Muderspach, L.I.3
  • 53
    • 34548128005 scopus 로고    scopus 로고
    • Heat shock fusion protein-based immunotherapy for treatment of cervical intraepithelial neoplasia III
    • Einstein MH, Kadish AS, Burk RD, et al. Heat shock fusion protein-based immunotherapy for treatment of cervical intraepithelial neoplasia III. Gynecol Oncol. 2007;106:453-460.
    • (2007) Gynecol Oncol , vol.106 , pp. 453-460
    • Einstein, M.H.1    Kadish, A.S.2    Burk, R.D.3
  • 54
    • 3042723816 scopus 로고    scopus 로고
    • Phase I/II trial of immunogenicity of a human papillomavirus (HPV) type 16 E7 protein-based HPV-positive cervical intraepithelial neoplasia
    • Hallez S, Simon P, Maudoux F, et al. Phase I/II trial of immunogenicity of a human papillomavirus (HPV) type 16 E7 protein-based HPV-positive cervical intraepithelial neoplasia. Cancer Immunol Immunother. 2004;53:642-650.
    • (2004) Cancer Immunol Immunother , vol.53 , pp. 642-650
    • Hallez, S.1    Simon, P.2    Maudoux, F.3
  • 55
    • 8644252813 scopus 로고    scopus 로고
    • Phase 1 study of HPV16-specific immunotherapy with E6E7 fusion protein and ISCOMATRIX adjuvant in women with cervical intraepithelial neoplasia
    • Frazer IH, Quinn M, Nicklin JL, et al. Phase 1 study of HPV16-specific immunotherapy with E6E7 fusion protein and ISCOMATRIX adjuvant in women with cervical intraepithelial neoplasia. Vaccine. 2004;23:172-181.
    • (2004) Vaccine , vol.23 , pp. 172-181
    • Frazer, I.H.1    Quinn, M.2    Nicklin, J.L.3
  • 56
    • 0037019901 scopus 로고    scopus 로고
    • Enhancement of human papillomavirus (HPV) type 16 E6 and E7-specific T-cell immunity in healthy volunteers through vaccination with TA-CIN, an HPV16 L2E7E6 fusion protein vaccine
    • de Jong A, O'Neill T, Khan AY, et al. Enhancement of human papillomavirus (HPV) type 16 E6 and E7-specific T-cell immunity in healthy volunteers through vaccination with TA-CIN, an HPV16 L2E7E6 fusion protein vaccine. Vaccine. 2002;20:3456-3464.
    • (2002) Vaccine , vol.20 , pp. 3456-3464
    • De Jong, A.1    O'Neill, T.2    Khan, A.Y.3
  • 57
    • 84902261184 scopus 로고    scopus 로고
    • Immunologic treatments for precancerous lesions and uterine cervical cancer
    • Vici P, Mariani L, Pizzuti L, et al. Immunologic treatments for precancerous lesions and uterine cervical cancer. J Exp Clin Cancer Res. 2014;33:29.
    • (2014) J Exp Clin Cancer Res , vol.33 , pp. 29
    • Vici, P.1    Mariani, L.2    Pizzuti, L.3
  • 58
    • 73949130821 scopus 로고    scopus 로고
    • Serological response to an HPV16 E7 based therapeutic vaccine in women with high-grade cervical dysplasia
    • Van Doorslaer K, Reimers LL, Studentsov YY, et al. Serological response to an HPV16 E7 based therapeutic vaccine in women with high-grade cervical dysplasia. Gynecol Oncol. 2010;116:208-212.
    • (2010) Gynecol Oncol , vol.116 , pp. 208-212
    • Van Doorslaer, K.1    Reimers, L.L.2    Studentsov, Y.Y.3
  • 59
    • 84910028030 scopus 로고    scopus 로고
    • New strategies in cervical cancer: From angiogenesis blockade to immunotherapy
    • Tewari KS, Monk BJ. New strategies in cervical cancer: from angiogenesis blockade to immunotherapy. Clin Cancer Res. 2014;20:5349-5358.
    • (2014) Clin Cancer Res , vol.20 , pp. 5349-5358
    • Tewari, K.S.1    Monk, B.J.2
  • 60
    • 79959840034 scopus 로고    scopus 로고
    • Immunization with a poly (lactide co-glycolide) encapsulated plasmid DNA expressing antigenic regions of HPV 16 and 18 results in an increase in the precursor frequency of T cells that respond to epitopes from HPV 16, 18, 6 and 11
    • Matijevic M, Hedley ML, Urban RG, et al. Immunization with a poly (lactide co-glycolide) encapsulated plasmid DNA expressing antigenic regions of HPV 16 and 18 results in an increase in the precursor frequency of T cells that respond to epitopes from HPV 16, 18, 6 and 11. Cell Immunol. 2011;270:62-69.
    • (2011) Cell Immunol , vol.270 , pp. 62-69
    • Matijevic, M.1    Hedley, M.L.2    Urban, R.G.3
  • 61
    • 1442305202 scopus 로고    scopus 로고
    • ZYC101a for treatment of high-grade cervical intraepithelial neoplasia: A randomized controlled trial
    • Garcia F, Petry KU, Muderspach L, et al. ZYC101a for treatment of high-grade cervical intraepithelial neoplasia: a randomized controlled trial. Obstet Gynecol. 2004;103:317-326.
    • (2004) Obstet Gynecol , vol.103 , pp. 317-326
    • Garcia, F.1    Petry, K.U.2    Muderspach, L.3
  • 62
    • 84867437406 scopus 로고    scopus 로고
    • Immunotherapy against HPV16/18 generates potent TH1 and cytotoxic cellular immune responses
    • Bagarazzi ML, Yan J, Morrow MP, et al. Immunotherapy against HPV16/18 generates potent TH1 and cytotoxic cellular immune responses. Sci Trans Med. 2012;4:155ra38.
    • (2012) Sci Trans Med , vol.4 , pp. 155ra38
    • Bagarazzi, M.L.1    Yan, J.2    Morrow, M.P.3
  • 63
    • 79957879852 scopus 로고    scopus 로고
    • PROVENGE (Sipuleucel-T) in prostate cancer: The first FDA-approved therapeutic cancer vaccine
    • Cheever MA, Higano CS. PROVENGE (Sipuleucel-T) in prostate cancer: the first FDA-approved therapeutic cancer vaccine. Clin Cancer Res. 2011;17:3520-3526.
    • (2011) Clin Cancer Res , vol.17 , pp. 3520-3526
    • Cheever, M.A.1    Higano, C.S.2
  • 64
    • 34548653937 scopus 로고    scopus 로고
    • Sipuleucel-T (Provenge): Active cellular immunotherapy for advanced prostate cancer
    • McKarney I. Sipuleucel-T (Provenge): active cellular immunotherapy for advanced prostate cancer. Issues Emerg Health Technol. 2007;101:1-4.
    • (2007) Issues Emerg Health Technol , vol.101 , pp. 1-4
    • McKarney, I.1
  • 65
    • 0141528515 scopus 로고    scopus 로고
    • Dendritic cell-based tumor vaccine for cervical cancer II: Results of a clinical pilot study in 15 individual patients
    • Ferrara A, Nonn M, Sehr P, et al. Dendritic cell-based tumor vaccine for cervical cancer II: results of a clinical pilot study in 15 individual patients. J Cancer Res Clin Oncol. 2003;129:521-530.
    • (2003) J Cancer Res Clin Oncol , vol.129 , pp. 521-530
    • Ferrara, A.1    Nonn, M.2    Sehr, P.3
  • 66
    • 38849136611 scopus 로고    scopus 로고
    • Human papillomavirus type 16 and 18 E7-pulsed dendritic cell vaccination of stage IB or IIA cervical cancer patients: A phase I escalating-dose trial
    • Santin AD, Bellone S, Palmieri M, et al. Human papillomavirus type 16 and 18 E7-pulsed dendritic cell vaccination of stage IB or IIA cervical cancer patients: a phase I escalating-dose trial. J Virol. 2008;82:1968-1979.
    • (2008) J Virol , vol.82 , pp. 1968-1979
    • Santin, A.D.1    Bellone, S.2    Palmieri, M.3
  • 67
    • 84920826958 scopus 로고    scopus 로고
    • Unleashing the clinical power of T cells: CD19/CD3 bispecific T cell engager (BiTE(R)) antibody construct blinatumomab as a potential therapy
    • Sep 19. [Epub ahead of print]
    • Zimmerman Z, Maniar T, Nagorsen D. Unleashing the clinical power of T cells: CD19/CD3 bispecific T cell engager (BiTE(R)) antibody construct blinatumomab as a potential therapy. Int Immunol. 2014 Sep 19. [Epub ahead of print].
    • (2014) Int Immunol
    • Zimmerman, Z.1    Maniar, T.2    Nagorsen, D.3
  • 68
    • 84908145811 scopus 로고    scopus 로고
    • Chimeric antigen receptor for adoptive immunotherapy of cancer: Latest research and future prospects
    • Shi H, Sun M, Liu L, Wang Z. Chimeric antigen receptor for adoptive immunotherapy of cancer: latest research and future prospects. Mol Cancer. 2014;13:219.
    • (2014) Mol Cancer , vol.13 , pp. 219
    • Shi, H.1    Sun, M.2    Liu, L.3    Wang, Z.4
  • 69
    • 84890180201 scopus 로고    scopus 로고
    • Design and implementation of adoptive therapy with chimeric antigen receptor-modified T cells
    • Jensen MC, Riddell SR. Design and implementation of adoptive therapy with chimeric antigen receptor-modified T cells. Immunol Rev. 2014;257:127-144.
    • (2014) Immunol Rev , vol.257 , pp. 127-144
    • Jensen, M.C.1    Riddell, S.R.2
  • 70
    • 84890181067 scopus 로고    scopus 로고
    • Design and development of therapies using chimeric antigen receptor-expressing T cells
    • Dotti G, Gottschalk S, Savoldo B, Brenner MK. Design and development of therapies using chimeric antigen receptor-expressing T cells. Immunol Rev. 2014;257:107-126.
    • (2014) Immunol Rev , vol.257 , pp. 107-126
    • Dotti, G.1    Gottschalk, S.2    Savoldo, B.3    Brenner, M.K.4
  • 71
    • 84908073316 scopus 로고    scopus 로고
    • Chimeric antigen receptor T cells for sustained remissions in leukemia
    • Maude SL, Frey N, Shaw PA, et al. Chimeric antigen receptor T cells for sustained remissions in leukemia. N Engl J Med.. 2014;371:1507-1517.
    • (2014) N Engl J Med , vol.371 , pp. 1507-1517
    • Maude, S.L.1    Frey, N.2    Shaw, P.A.3
  • 72
    • 84892682607 scopus 로고    scopus 로고
    • Immunotherapy with chimeric antigen receptors for multiple myeloma
    • Garfall AL, Fraietta JA, Maus MV. Immunotherapy with chimeric antigen receptors for multiple myeloma. Discov Med. 2014;17:37-46.
    • (2014) Discov Med , vol.17 , pp. 37-46
    • Garfall, A.L.1    Fraietta, J.A.2    Maus, M.V.3
  • 73
    • 84939943612 scopus 로고    scopus 로고
    • T Cells Engineered with a Chimeric Antigen Receptor (CAR) Targeting CD19 (CTL019) Have Long Term Persistence and Induce Durable Remissions in Children with Relapsed
    • Grupp SA, Maude SL, Shaw P, et al. T Cells Engineered with a Chimeric Antigen Receptor (CAR) Targeting CD19 (CTL019) Have Long Term Persistence and Induce Durable Remissions in Children with Relapsed. Refractory ALL. Blood. 2014. Abtsract 380.
    • (2014) Refractory ALL. Blood
    • Grupp, S.A.1    Maude, S.L.2    Shaw, P.3
  • 74
    • 84886809704 scopus 로고    scopus 로고
    • Tumor and T cell engagement by BiTE
    • Wickramasinghe D. Tumor and T cell engagement by BiTE. Discov Med. 2013;16:149-152.
    • (2013) Discov Med , vol.16 , pp. 149-152
    • Wickramasinghe, D.1
  • 75
    • 84916639631 scopus 로고    scopus 로고
    • Phase II Trial of the Anti-CD19 Bispecific T Cell-Engager Blinatumomab Shows Hematologic and Molecular Remissions in Patients With Relapsed or Refractory B-Precursor Acute Lymphoblastic Leukemia
    • Nov 10. [Epub ahead of print]
    • Topp MS, Gokbuget N, Zugmaier G, et al. Phase II Trial of the Anti-CD19 Bispecific T Cell-Engager Blinatumomab Shows Hematologic and Molecular Remissions in Patients With Relapsed or Refractory B-Precursor Acute Lymphoblastic Leukemia. J Clin Oncol. 2014 Nov 10. [Epub ahead of print].
    • (2014) J Clin Oncol
    • Topp, M.S.1    Gokbuget, N.2    Zugmaier, G.3
  • 76
    • 84920826956 scopus 로고    scopus 로고
    • Redirected T-cell killing of solid cancers targeted with an anti- CD3/Trop-2-bispecific antibody is enhanced in combination with interferon-alpha
    • Rossi EA, Rossi DL, Cardillo TM, Chang CH, Goldenberg DM. Redirected T-cell killing of solid cancers targeted with an anti- CD3/Trop-2-bispecific antibody is enhanced in combination with interferon-alpha. Mol Cancer Ther. 2014;13:2341-2351.
    • (2014) Mol Cancer Ther , vol.13 , pp. 2341-2351
    • Rossi, E.A.1    Rossi, D.L.2    Cardillo, T.M.3    Chang, C.H.4    Goldenberg, D.M.5
  • 77
    • 84907521152 scopus 로고    scopus 로고
    • HPV-targeted tumor-infiltrating lymphocytes for cervical cancer
    • Hinrichs CS, Stevanovic S, Draper L, et al. HPV-targeted tumor-infiltrating lymphocytes for cervical cancer. J Clin Oncol. 2014;32 (Suppl 5): Abstract LBA3008.
    • (2014) J Clin Oncol , vol.32
    • Hinrichs, C.S.1    Stevanovic, S.2    Draper, L.3
  • 78
    • 41149097574 scopus 로고    scopus 로고
    • Adoptive cell transfer: A clinical path to effective cancer immunotherapy
    • Rosenberg SA, Restifo NP, Yang JC. Adoptive cell transfer: a clinical path to effective cancer immunotherapy. Nat Rev Cancer. 2008;8:299-308.
    • (2008) Nat Rev Cancer , vol.8 , pp. 299-308
    • Rosenberg, S.A.1    Restifo, N.P.2    Yang, J.C.3
  • 79
    • 84920849759 scopus 로고    scopus 로고
    • Presented at Poster Presentation 1116PD
    • Lebbe C, et al. Presented at ESMO 2012; Poster Presentation 1116PD.
    • ESMO 2012
    • Lebbe, C.1
  • 80
    • 84920864159 scopus 로고    scopus 로고
    • State-of-the-art treatment for advanced melanoma
    • Mayor S. State-of-the-art treatment for advanced melanoma. Cancer World. 2011:e1-e20.
    • (2011) Cancer World , pp. e1-e20
    • Mayor, S.1
  • 81
    • 84892171528 scopus 로고    scopus 로고
    • Clinical Implications of Co-Inhibitory Molecule Expression in the Tumor Microenvironment for DC Vaccination: AGame of Stop and Go
    • Vasaturo A, Di Blasio S, Peeters DG, et al. Clinical Implications of Co-Inhibitory Molecule Expression in the Tumor Microenvironment for DC Vaccination: AGame of Stop and Go. Front Immunol. 2013;4:417.
    • (2013) Front Immunol , vol.4 , pp. 417
    • Vasaturo, A.1    Di Blasio, S.2    Peeters, D.G.3
  • 82
    • 84875475811 scopus 로고    scopus 로고
    • Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma
    • Lyford-Pike S, Peng S, Young GD, et al. Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma. Cancer Res. 2013;73:1733-1741.
    • (2013) Cancer Res , vol.73 , pp. 1733-1741
    • Lyford-Pike, S.1    Peng, S.2    Young, G.D.3
  • 83
    • 84908354848 scopus 로고    scopus 로고
    • Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: A randomised dose-comparison cohort of a phase 1 trial
    • Robert C, Ribas A, Wolchok JD, et al. Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial. Lancet. 2014;384:1109-1117.
    • (2014) Lancet , vol.384 , pp. 1109-1117
    • Robert, C.1    Ribas, A.2    Wolchok, J.D.3
  • 84
    • 84879599112 scopus 로고    scopus 로고
    • At the bedside: CTLA-4- and PD-1-blocking antibodies in cancer immunotherapy
    • Callahan MK, Wolchok JD. At the bedside: CTLA-4- and PD-1-blocking antibodies in cancer immunotherapy. J Leukoc Biol. 2013;94:41-53.
    • (2013) J Leukoc Biol , vol.94 , pp. 41-53
    • Callahan, M.K.1    Wolchok, J.D.2
  • 85
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma
    • Hodi FS, O'Day SJ, McDermott DF, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med. 2010;363:711-723.
    • (2010) N Engl J Med , vol.363 , pp. 711-723
    • Hodi, F.S.1    O'Day, S.J.2    McDermott, D.F.3
  • 86
    • 84890933692 scopus 로고    scopus 로고
    • Phosphatidylserine-targeting antibody induces M1 macrophage polarization and promotes myeloidderived suppressor cell differentiation
    • Yin Y, Huang X, Lynn KD, Thorpe PE. Phosphatidylserine-targeting antibody induces M1 macrophage polarization and promotes myeloidderived suppressor cell differentiation. Cancer Immunol Res. 2013;1:256-268.
    • (2013) Cancer Immunol Res , vol.1 , pp. 256-268
    • Yin, Y.1    Huang, X.2    Lynn, K.D.3    Thorpe, P.E.4
  • 87
    • 84880511594 scopus 로고    scopus 로고
    • Development of ipilimumab: A novel immunotherapeutic approach for the treatment of advanced melanoma
    • Wolchok JD, Hodi FS, Weber JS, et al. Development of ipilimumab: a novel immunotherapeutic approach for the treatment of advanced melanoma. Ann N Y Acad Sci. 2013;1291:1-13.
    • (2013) Ann N Y Acad Sci , vol.1291 , pp. 1-13
    • Wolchok, J.D.1    Hodi, F.S.2    Weber, J.S.3
  • 88
    • 73149092567 scopus 로고    scopus 로고
    • Guidelines for the evaluation of immune therapy activity in solid tumors: Immune-related response criteria
    • Wolchok JD, Hoos A, O'Day S, et al. Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria. Clin Cancer Res. 2009;15:7412-7420.
    • (2009) Clin Cancer Res , vol.15 , pp. 7412-7420
    • Wolchok, J.D.1    Hoos, A.2    O'Day, S.3
  • 90
    • 84880682724 scopus 로고    scopus 로고
    • Novel antibodies targeting immune regulatory checkpoints for cancer therapy
    • Lee CS, Cragg M, Glennie M, Johnson P. Novel antibodies targeting immune regulatory checkpoints for cancer therapy. Br J Clin Pharmacol. 2013;76:233-247.
    • (2013) Br J Clin Pharmacol , vol.76 , pp. 233-247
    • Lee, C.S.1    Cragg, M.2    Glennie, M.3    Johnson, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.