Lm-LLO-based immunotherapies and HPV-associated disease

Journal of Oncology

Volumn , Issue , 2012, Pages

  Wallecha, Anu ^a   French, Chris ^a   Petit, Robert ^a   Singh, Reshma ^a   Amin, Ashok ^a   Rothman, John ^a  

^a ADVAXIS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADXS 11 001; ANTINEOPLASTIC AGENT; BACTERIAL PROTEIN; BACTERIAL VECTOR; CAPSID PROTEIN; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYBRID PROTEIN; IMMUNOLOGIC AGENT; INTERLEUKIN 12; INTERLEUKIN 18; INTERLEUKIN 6; INTERLEUKIN 8; LISTERIOLYSIN O; RECOMBINANT LISTERIOLYSIN O; RECOMBINANT PROTEIN; RECOMBINANT VACCINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VIRUS DNA;

ADJUVANT THERAPY; ANTIBIOTIC THERAPY; ANTIGEN PRESENTATION; ANTINEOPLASTIC ACTIVITY; ATTENUATION; CANCER ADJUVANT THERAPY; CANCER IMMUNOTHERAPY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL DIVISION; CELL MATURATION; CELLULAR IMMUNITY; CYTOTOXICITY; DISEASE ASSOCIATION; DRUG EFFICACY; DRUG SAFETY; EPITHELIUM BASAL CELL; HEAD AND NECK CANCER; HUMAN; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; IMMUNOSTIMULATION; INTRACELLULAR MEMBRANE; KERATINOCYTE; LISTERIA MONOCYTOGENES; MEMORY T LYMPHOCYTE; NEOPLASM; NONHUMAN; OUTCOME ASSESSMENT; PAPILLOMAVIRUS INFECTION; PHAGOLYSOSOME; PHASE 2 CLINICAL TRIAL (TOPIC); PROTEIN EXPRESSION; REVIEW; TUMOR ASSOCIATED LEUKOCYTE; UPREGULATION; UTERINE CERVIX CANCER; UTERINE CERVIX CARCINOMA IN SITU; VAGINAL INTRAEPITHELIAL NEOPLASIA; VIRUS GENE; WART VIRUS;

EID: 84863258367     PISSN: 16878450     EISSN: 16878469     Source Type: Journal    
DOI: 10.1155/2012/542851     Document Type: Review

References (51)

1. Parkin D. M., The global health burden of infection-associated cancers in the year 2002 International Journal of Cancer 2006 118 12 3030 3044
2. D'Souza G., Kreimer A. R., Viscidi R., Pawlita M., Fakhry C., Koch W. M., Westra W. H., Gillison M. L., Case-control study of human papillomavirus and oropharyngeal cancer The New England Journal of Medicine 2007 356 19 1944 1956 (Pubitemid 46740304)
3. Brandsma J. L., Abramson A. L., Association of papillomavirus with cancers of the head and neck Archives of OtolaryngologyHead and Neck Surgery 1989 115 5 621 625 (Pubitemid 19130305)
4. Loddenkemper C., Hoffmann C., Stanke J., Nagorsen D., Baron U., Olek S., Huehn J., Ritz J. P., Stein H., Kaufmann A. M., Schneider A., Cichon G., Regulatory (FOXP3+) T cells as target for immune therapy of cervical intraepithelial neoplasia and cervical cancer Cancer Science 2009 100 6 1112 1117
5. Lohavanichbutr P., Houck J., Fan W., Yueh B., Mendez E., Futran N., Doody D. R., Upton M. P., Farwell D. G., Schwartz S. M., Zhao L. P., Chen C., Genomewide gene expression profiles of HPV-positive and HPV-negative oropharyngeal cancer potential implications for treatment choices Archives of OtolaryngologyHead and Neck Surgery 2009 135 2 180 188
6. Chocolatewala N., Chaturvedi P., Role of human papilloma virus in the oral carcinogenesis: an Indian perspective Journal of Cancer Research and Therapeutics 2009 5 2 71 77
7. Gunn G. R., Zubair A., Peters C., Pan Z. K., Wu T. C., Paterson Y., Two Listeria monocytogenes vaccine vectors that express different molecular forms of human papilloma virus-16 (HPV-16) E7 induce qualitatively different T cell immunity that correlates with their ability to induce regression of established tumors immortalized by HPV-16 Journal of Immunology 2001 167 11 6471 6479 (Pubitemid 33081581)
8. Sewell D. A., Shahabi V., Gunn G. R. III, Pan Z. K., Dominiecki M. E., Paterson Y., Recombinant Listeria vaccines containing PEST sequences are potent immune adjuvants for the tumor-associated antigen human papillomavirus-16 E7 Cancer Research 2004 64 24 8821 8825 (Pubitemid 39665484)
9. Verch T., Pan Z. K., Paterson Y., Listeria monocytogenes-based antibiotic resistance gene-free antigen delivery system applicable to other bacterial vectors and DNA vaccines Infection and Immunity 2004 72 11 6418 6425 (Pubitemid 39425422)
10. Jabbar S. F., Abrams L., Glick A., Lambert P. F., Persistence of high-grade cervical dysplasia and cervical cancer requires the continuous expression of the human papillomavirus type 16 E7 oncogene Cancer Research 2009 69 10 4407 4414
11. Zur Hausen H., Papillomaviruses and cancer: from basic studies to clinical application Nature Reviews Cancer 2002 2 5 342 350 (Pubitemid 37328947)
12. vestad I. T., Gudlaugsson E., Skaland I., Malpica A., Kruse A. J., Janssen E. A. M., Baak J. P. A., Local immune response in the microenvironment of CIN2-3 with and without spontaneous regression Modern Pathology 2010 23 9 1231 1240
13. Adurthi S., Krishna S., Mukherjee G., Bafna U. D., Devi U., Jayshree R. S., Regulatory T cells in a spectrum of HPV-induced cervical lesions: cervicitis, cervical intraepithelial neoplasia and squamous cell carcinoma The American Journal of Reproductive Immunology 2008 60 1 55 65 (Pubitemid 351844100)
14. Patel S., Chiplunkar S., Host immune responses to cervical cancer Current Opinion in Obstetrics and Gynecology 2009 21 1 54 59
15. Hussain S. F., Paterson Y., Regulatory T cells that secreast TGF and IL-10 are preferentially induced by a vaccine vector Journal of Immunotherapy 2004 27 5 339 346 (Pubitemid 39121922)
16. Nitcheu-Tefit J., Dai M. S., Critchley-Thorne R. J., Ramirez-Jimenez F., Xu M., Conchon S., Ferry N., Stauss H. J., Vassaux G., Listeriolysin O expressed in a bacterial vaccine suppresses CD4 + CD25 high regulatory T cell function in vivo Journal of Immunology 2007 179 3 1532 1541
17. Shahabi V., Reyes-Reyes M., Wallecha A., Rivera S., Paterson Y., Maciag P., Development of a Listeria monocytogenes based vaccine against prostate cancer Cancer Immunology, Immunotherapy 2008 57 9 1301 1313
18. Shahabi V., Seavey M. M., MacIag P. C., Rivera S., Wallecha A., Development of a live and highly attenuated Listeria monocytogenes-based vaccine for the treatment of Her2/neu-overexpressing cancers in human Cancer Gene Therapy 2011 18 1 1 10
19. Maciag P. C., Radulovic S., Rothman J., The first clinical use of a live-attenuated Listeria monocytogenes vaccine: a Phase I safety study of Lm -LLO-E7 in patients with advanced carcinoma of the cervix Vaccine 2009 27 30 3975 3983
20. Rothman J., Wallecha A., Maciag P. C., Rivera S., Shahabi V., Paterson Y., Fialho A. M., Chakrabarty A. M., The use of a living Listeria monocytogenes as an active immunotherapy for the treatment of cancer Emerging Cancer Therapy: Microbial Approaches and Biotechnological Tools 2010 New York, NY, USA John Wiley Sons
21. Campisi L., Soudja S. M., Cazareth J., Bassand D., Lazzari A., Brau F., Narni-Mancinelli E., Glaichenhaus N., Geissmann F., Lauvau G., Splenic CD8 + dendritic cells undergo rapid programming by cytosolic bacteria and inflammation to induce protective CD8 + T-cell memory European Journal of Immunology 2011 41 1594 1605
22. Weiskirch L. M., Paterson Y., Listeria monocytogenes: a potent vaccine vector for neoplastic and infectious disease Immunological Reviews 1997 158 159 169 (Pubitemid 27379553)
23. Singh R., Wallecha A., Cancer immunotherapy using recombinant Listeria monocytogenes: transition from bench to clinic Human Vaccines 2011 7 5 497 505
24. Wallecha A., Maciag P. C., Rivera S., Paterson Y., Shahabi V., Construction and characterization of an attenuated Listeria monocytogenes strain for clinical use in cancer immunotherapy Clinical and Vaccine Immunology 2009 16 1 96 103
25. Dramsi S., Cossart P., Listeriolysin O: a genuine cytolysin optimized for an intracellular parasite Journal of Cell Biology 2002 156 6 943 946 (Pubitemid 34839843)
26. Schmidt C. S., Morrow W. J. W., Sheikh N. A., Smart adjuvants Expert Review of Vaccines 2007 6 3 391 400 (Pubitemid 46911602)
27. Neeson P., Pan Z. K., Paterson Y., Listeriolysin O is an improved protein carrier for lymphoma immunoglobulin idiotype and provides systemic protection against 38C13 lymphoma Cancer Immunology, Immunotherapy 2008 57 4 493 505 (Pubitemid 351170533)
28. Paterson Y., Rational approaches to immune regulation Immunologic Research 2003 27 2-3 451 462
29. Peng X., Treml J., Paterson Y., Adjuvant properties of listeriolysin O protein in a DNA vaccination strategy Cancer Immunology, Immunotherapy 2007 56 6 797 806 (Pubitemid 46723587)
30. Shahabi V., Maciag P. C., Rivera S., Wallecha A., Live, attenuated strains of Listeria and Salmonella as vaccine vectors in cancer treatment Bioengineered Bugs 2010 1 4 235 243
31. Vzquez-Boland J. A., Kuhn M., Berche P., Chakraborty T., Domnguez-Bernal G., Goebel W., Gonzlez-Zorn B., Wehland J., Kreft J., Listeria pathogenesis and molecular virulence determinants Clinical Microbiology Reviews 2001 14 3 584 640 (Pubitemid 32642752)
32. Singh R., Dominiecki M. E., Jaffee E. M., Paterson Y., Fusion to Listeriolysin O and delivery by Listeria monocytogenes enhances the immunogenicity of HER-2/neu and reveals subdominant epitopes in the FVB/N mouse Journal of Immunology 2005 175 6 3663 3673 (Pubitemid 41292026)
33. Berg R. E., Crossley E., Murray S., Forman J., Relative contributions of NK and CD8 T cells to IFN- mediated innate immune protection against Listeria monocytogenes Journal of Immunology 2005 175 3 1751 1757 (Pubitemid 41023079)
34. Ikonomidis G., Paterson Y., Kos F. J., Portnoy D. A., Delivery of a viral antigen to the class I processing and presentation pathway by Listeria monocytogenes Journal of Experimental Medicine 1994 180 6 2209 2218 (Pubitemid 24351602)
35. MacFarlane A. S., Huang D., Schwacha M. G., Meissler J. J., Gaughan J. P., Eisenstein T. K., Nitric oxide mediates immunosuppression induced by Listeria monocytogenes infection: quantitative studies Microbial Pathogenesis 1998 25 5 267 277 (Pubitemid 29004735)
36. dos Santos S. A., de Andrade Jnior D. R., de Andrade D. R., TNF- production and apoptosis in hepatocytes after Listeria monocytogenes and Salmonella Typhimurium invasion Revista do Instituto de Medicina Tropical de Sao Paulo 2011 53 2 107 112
37. Iizawa Y., Brown J. F., Czuprynski C. J., Early expression of cytokine mRNA in mice infected with Listeria monocytogenes Infection and Immunity 1992 60 10 4068 4073
38. Freeman M. M., Ziegler H. K., Simultaneous Th1-type cytokine expression is a signature of peritoneal CD4+ lymphocytes responding to infection with Listeria monocytogenes Journal of Immunology 2005 175 1 394 403 (Pubitemid 40884343)
39. Demuth A., Goebel W., Ulrich Beuscher H., Kuhn M., Differential regulation of cytokine and cytokine receptor mRNA expression upon infection of bone marrow-derived macrophages with Listeria monocytogenes Infection and Immunity 1996 64 9 3475 3483 (Pubitemid 26298663)
40. Nishibori T., Xiong H., Kawamura I., Arakawa M., Mitsuyama M., Induction of cytokine gene expression by listeriolysin O and roles of macrophages and NK cells Infection and Immunity 1996 64 8 3188 3195 (Pubitemid 26256164)
41. Bajénoff M., Narni-Mancinelli E., Brau F., Lauvau G., Visualizing early splenic memory CD8+ T cells reactivation against intracellular bacteria in the mouse PLoS One 2010 5 7
42. Corbin G. A., Harty J. T., Duration of infection and antigen display have minimal influence on the kinetics of the CD4+ T cell response to Listeria monocytogenes infection Journal of Immunology 2004 173 9 5679 5687 (Pubitemid 39392156)
43. Hamon M., Bierne H., Cossart P., Listeria monocytogenes: a multifaceted model Nature Reviews Microbiology 2006 4 6 423 434 (Pubitemid 43771862)
44. Kolb-Murer A., Weissinger F., Kurzai O., Murer M., Wilhelm M., Goebel W., Bacterial infection of human hematopoietic stem cells induces monocytic differentiation FEMS Immunology and Medical Microbiology 2004 40 2 147 153 (Pubitemid 38249539)
45. Whiteside T. L., Immune suppression in cancer: effects on immune cells, mechanisms and future therapeutic intervention Seminars in Cancer Biology 2006 16 1 3 15 (Pubitemid 43139705)
46. Drevets D. A., Listeria monocytogenes infection of cultured endothelial cells stimulates neutrophil adhesion and adhesion molecule expression Journal of Immunology 1997 158 11 5305 5313 (Pubitemid 127681236)
47. Drevets D. A., Listeria monocytogenes virulence factors that stimulate endothelial cells Infection and Immunity 1998 66 1 232 238 (Pubitemid 28018825)
48. Kayal S., Lilienbaum A., Poyart C., Memet S., Israel A., Berche P., Listeriolysin O-dependent activation of endothelial cells during infection with Listeria monocytogenes: activation of NF- B and upregulation of adhesion molecules and chemokines Molecular Microbiology 1999 31 6 1709 1722 (Pubitemid 29151271)
49. Sewell D. A., Douven D., Pan Z. K., Rodriguez A., Paterson Y., Regression of HPV-positive tumors treated with a new Listeria monocytogenes vaccine Archives of OtolaryngologyHead and Neck Surgery 2004 130 1 92 97 (Pubitemid 38095437)
50. Lamikanra A., Pan Z. K., Isaacs S. N., Wu T. C., Paterson Y., Regression of established human papillomavirus type 16 (HPV-16) immortalized tumors in vivo by vaccinia viruses expressing different forms of HPV-16 E7 correlates with enhanced CD8+ T-cell responses that home to the tumor site Journal of Virology 2001 75 20 9654 9664 (Pubitemid 32900100)
51. Kim S. H., Castro F., Paterson Y., Gravekamp C., High efficacy of a Listeria-based vaccine against metastatic breast cancer reveals a dual mode of action Cancer Research 2009 69 14 5860 5866