Targeting delivery of etoposide to inhibit the growth of human glioblastoma multiforme using lactoferrin- and folic acid-grafted poly(lactide-co-glycolide) nanoparticles

International Journal of Pharmaceutics

Volumn 479, Issue 1, 2015, Pages 138-149

  Kuo, Yung Chih ^a   Chen, Yu Chun ^a  

^a NATIONAL CHUNG CHENG UNIVERSITY   (Taiwan)

Author keywords

Blood brain barrier; Etoposide; Folic acid; Glioblastoma multiforme; Lactoferrin; Poly(lactide co glycolide)

Indexed keywords

ETOPOSIDE; FOLATE RECEPTOR; FOLIC ACID; LACTOFERRIN; LACTOFERRIN FOLIC ACID POY(LACTIDE CO GLYCOLIDE) NANOPARTICLE; NANOPARTICLE; POLYGLACTIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CELL SURFACE RECEPTOR; GYRASE INHIBITOR; LACTIC ACID; LACTOFERRIN RECEPTORS; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; CANCER INHIBITION; CELL DENSITY; CELL MEMBRANE PERMEABILITY; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CROSS LINKING; DRUG CONJUGATION; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG PENETRATION; DRUG SOLUBILITY; DRUG TRANSPORT; ELECTRIC RESISTANCE; ELECTROPHORETIC MOBILITY; ENDOCYTOSIS; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; GEOMETRY; GLIOBLASTOMA; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INTERNALIZATION; MOLECULAR WEIGHT; OPTICAL DENSITY; PARTICLE SIZE; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SURFACE CHARGE; SUSTAINED DRUG RELEASE; TRANSCYTOSIS; ZETA POTENTIAL; BRAIN TUMOR; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; METABOLISM; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL LINE; ULTRASTRUCTURE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; ASTROCYTES; BLOOD-BRAIN BARRIER; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; DRUG DELIVERY SYSTEMS; ENDOTHELIAL CELLS; ETOPOSIDE; FOLATE RECEPTORS, GPI-ANCHORED; FOLIC ACID; GLIOBLASTOMA; HUMANS; LACTIC ACID; LACTOFERRIN; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; POLYGLYCOLIC ACID; RECEPTORS, CELL SURFACE; TOPOISOMERASE II INHIBITORS;

EID: 84920815199     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.12.070     Document Type: Article

References (44)

1. K. Avgoustakis, A. Beletsi, Z. Panagi, P. Klepetsanis, A.G. Karydas, and D.S. Ithakissios PLGA-mPEG nanoparticles of cisplatin: in vitro nanoparticle degradation, in vitro drug release and in vivo drug residence in blood properties J. Control. Release 79 2002 123 135
2. I. Bala, V.B. Hardwaj, S. Hariharan, J. Sitterberg, U. Bakowsky, and M.N.V. Ravi Kumar Design of biodegradable nanoparticles: a novel approach to encapsulating poorly soluble phytochemical ellagic acid Nanotechnology 16 2005 2819 2822
3. J. Bart, H.J.M. Groen, N.H. Hendrikse, W.T.A. van der Graaf, W. Vaalburg, and E.G.E. de Vries The blood-brain barrier and oncology: new insights into function and modulation Cancer Treat. Rev. 26 2000 49 462
4. V. Bhardwaj, D.D. Ankola, S.C. Gupta, M. Schneider, C.M. Lehr, and M.N.V. Ravi Kumar PLGA nanoparticles stabilized with cationic surfactant: safety studies and application in oral delivery of paclitaxel to treat chemical-induced breast cancer in rat Pharm. Res. 26 2009 2495 2503
5. A. Budhian, S.J. Siegel, and K.I. Winey Controlling the in vitro release profiles for a system of haloperidol-loaded PLGA nanoparticles Int. J. Pharm. 346 2008 151 159
6. M.K. Callahan, K.A. Williams, P. Kivisakk, D. Pearce, M.F. Stins, and R.M. Ransohoff CXCR3 marks CD4+ memory T lymphocytes that are competent to migrate across a human brain microvascular endothelial cell layer J. Neuroimmunol. 153 2004 150 157
7. M.C. Chamberlain Treatment options for glioblastoma Neurosurg. Focus 20 2006 E19
8. S.M. Chang, N.A. Butowski, P.K. Sneed, and I.V. Garner Standard treatment and experimental targeted drug therapy for recurrent glioblastoma multiforme Neurosurg. Focus 20 2006 E4
9. O.I. Corrigan, and X. Li Quantifying drug release from PLGA nanoparticulates Eur. J. Pharm. Sci. 37 2009 477 485
10. C. Fillebeen, L. Descamps, M.P. Dehouck, L. Fenart, M. Benaissa, G. Spik, R. Cecchelli, and A. Pierce Receptor-mediated transcytosis of lactoferrin through the blood-brain barrier J. Biol. Chem. 274 1999 7011 7017
11. P.L. Golden, T.J. Maccagnan, and W.M. Pardridge Human blood-brain barrier leptin receptor: binding and endocytosis in isolated human brain microvessels J. Clin. Invest. 99 1997 14 18
12. F.X. Gu, R. Karnik, A.Z. Wang, F. Alexis, E. Levy-Nissenbaum, S. Hong, R.S. Langer, and O.C. Farokhzad Targeted nanoparticles for cancer therapy Nano Today 2 2007 14 21
13. S. Hariharan, V. Bhardwaj, I. Bala, J. Sitterberg, U. Bakowsky, and M.N.V. Ravi Kumar Design of estradiol loaded PLGA nanoparticulate formulations: a potential oral delivery system for hormone therapy Pharm. Res. 23 2006 184 195
14. C.Y. Huang, C.M. Chen, and Y.D. Lee Synthesis of high loading and encapsulation efficient paclitaxel-loaded poly(n-butyl cyanoacrylate) nanoparticles via miniemulsion Int. J. Pharm. 338 2007 267 275
15. R.Q. Huang, W.L. Ke, Y.H. Qu, J.H. Zhu, Y.Y. Pei, and C. Jiang Characterization of lactoferrin receptor in brain endothelial capillary cells and mouse brain J. Biomed. Sci. 14 2007 121 128
16. R. Huang, W. Ke, L. Han, Y. Liu, K. Shao, L. Ye, J. Lou, C. Jiang, and Y. Pei Brain-targeting mechanisms of lactoferrin-modified DNA-loaded nanoparticles J. Cereb. Blood Flow Metab. 29 2009 1914 1923
17. B. Ji, A. Maeda, M. Higuchi, K. Inoue, H. Akita, H. Harashima, and T. Suhara Pharmacokinetics and brain uptake of lactoferrin in rats Life Sci. 78 2006 851 855
18. C.F. Jones, and D.W. Grainger In vitro assessments of nanomaterial toxicity Adv. Drug Deliv. Rev. 61 2009 438 456
19. T.S. Kim, A.L. Halliday, E.T. Hedley-Whyte, and K. Convery Correlates of survival and the Daumas-Duport grading system for astrocytomas J. Neurosurg. 74 1991 27 37
20. D. Klose, F. Siepmann, K. Elkharraz, and J. Siepmann PLGA-based drug delivery systems: importance of the type of drug and device geometry Int. J. Pharm. 354 2008 95 103
21. J.S. Kuo, C.H. Chang, Y.L. Lin, and C.J. Wu Flow cytometric characterization of interactions between U-937 human macrophages and positively charged catanionic vesicles Colloids Surf. B 64 2008 307 313
22. Y.C. Kuo, and P.R. Chou Neuroprotection against degeneration of SK-N-MC cells using neuron growth factor-encapsulated liposomes with surface cereport and transferrin J. Pharm. Sci. 103 2014 2484 2497
23. Y.C. Kuo, and T.Y. Hong Delivering etoposide to the brain using catanionic solid lipid nanoparticles with surface 5-HT-moduline Int. J. Pharm. 465 2014 132 142
24. Y.C. Kuo, and S.C. Lin Effect of glutamate on the electrical properties of cationic solid lipid nanoparticles containing stearylamine and dioctadecyldimethyl ammonium bromide J. Phys. Chem. B 112 2008 4454 4460
25. Y.C. Kuo, and C.T. Liang Inhibition of human brain malignant glioblastoma cells using carmustine-loaded catanionic solid lipid nanoparticles with surface anti-epithelial growth factor receptor Biomaterials 32 2011 3340 3350
26. Y.C. Kuo, and C.H. Lu Regulation of endocytosis into human brain-microvascular endothelial cells by inhibition of efflux proteins Colloids Surf. B 87 2011 139 145
27. Y.C. Kuo, and C.H. Lu Effect of human astrocytes on the characteristics of human brain-microvascular endothelial cells in the blood-brain barrier Colloids Surf. B 86 2011 225 231
28. Y.C. Kuo, and C.H. Lu Expression of P-glycoprotein and multidrug resistance-associated protein on human brain-microvascular endothelial cells with electromagnetic stimulation Colloids Surf. B 91 2012 57 62
29. Y.C. Kuo, and F.L. Su Transport of stavudine, delavirdine, and saquinavir across the blood-brain barrier by polybutylcyanoacrylate methylmethacrylate-sulfopropylmethacrylate, and solid lipid nanoparticles Int. J. Pharm. 340 2007 143 152
30. Y.C. Kuo, and L.J. Wang Transferrin-grafted catanionic solid lipid nanoparticles for targeting delivery of saquinavir to the brain J. Taiwan Inst. Chem. Eng. 45 2014 755 763
31. Y.C. Kuo, P.I. Lin, and C.C. Wang Targeting nevirapine delivery across human brain microvascular endothelial cells using transferrin-grafted poly(lactide-co-glycolide) nanoparticles Nanomedicine 6 2011 1011 1026
32. H.Y. Kwon, J.Y. Lee, S.W. Choi, Y. Jang, and J.H. Kim Preparation of PLGA nanoparticles containing estrogen by emulsification-diffusion method Colloids Surf. A 182 2001 123 130
33. V. Labhasetwar, C.X. Song, W. Humphrey, R. Shebuski, and R.J. Levy Arterial uptake of biodegradable nanoparticles: effect of surface modifications J. Pharm. Sci. 87 1998 1229 1234
34. V.J. Mohanraj, and Y. Chen Nanoparticles-a review Trop. J. Pharm. Res. 5 2006 561 573
35. M.N. Needle, P.T. Molloy, J.R. Geyer, A. Herman-Liu, J.B. Belasco, J.W. Goldwein, L. Sutton, and P.C. Phillips Phase II study of daily oral etoposide in children with recurrent brain tumors and other solid tumors Med. Pediatr. Oncol. 29 1997 28 32
36. Z. Pang, L. Feng, R. Hua, J. Chen, H. Gao, S. Pan, X. Jiang, and P. Zhang Lactoferrin-conjugated biodegradable polymersome holding doxorubicin and tetrandrine for chemotherapy of glioma rats Mol. Pharm. 7 2010 1995 2005
37. L.A.M. Rupert, D. Hoekstra, and J.B.F.N. Engberts Fusogenic behavior of didodecyldimethylammonium bromide bilayer vesicles J. Am. Chem. Soc. 107 1985 2628 2631
38. D.K. Sahana, G. Mittal, V. Bhardwaj, and M.N.V. Ravi Kumar PLGA nanoparticles for oral delivery of hydrophobic drugs: influence of organic solvent on nanoparticle formation and release behavior in vitro and in vivo using estradiol as a model drug J. Pharm. Sci. 97 2008 1530 1542
39. C.X. Song, V. Labhasetwar, X.M. Cui, T. Underwood, and R.J. Levy Arterial uptake of biodegradable nanoparticles for intravascular local drug delivery: results with an acute dog model J. Control. Release 54 1998 201 211
40. J.F. Wang, W.M. Liu, Q. Tu, J.C. Wang, N. Song, Y.R. Zhang, N. Nie, and J.Y. Wang Folate-decorated hybrid polymeric nanoparticles for chemically and physically combined paclitaxel loading and targeted delivery Biomacromolecules 12 2011 228 234
41. P.P. Ward, E. Paz, and O.M. Conneely Multifunctional roles of lactoferrin: a critical overview Cell. Mol. Life Sci. 62 2005 2540 2548
42. D.F. Wu, and W.M. Pardridge Blood-brain barrier transport of reduced folic acid Pharm. Res. 16 1999 415 419
43. H. Zhao, and L.Y.L. Yung Selectivity of folate conjugated polymer micelles against different tumor cells Int. J. Pharm. 349 2008 256 268
44. H. Zhao, and L.Y.L. Yung Addition of TPGS to folate-conjugated polymer micelles for selective tumor targeting J. Biomed. Mater. Res. A 91 2009 505 518