Upregulation of autophagy by hypoxia-inducible factor-1α promotes EMT and metastatic ability of CD133+ pancreatic cancer stem-like cells during intermittent hypoxia

Oncology Reports

Volumn 32, Issue 3, 2014, Pages 935-942

  Zhu, Haitao ^a   Wang, Dongqing ^a   Zhang, Lirong ^a   Xie, Xiaodong ^a   Wu, Yingying ^a   Liu, Yanfang ^b   Shao, Genbao ^a   Su, Zhaoliang ^a  

^a JIANGSU UNIVERSITY   (China)

^b First People's Hospital of Zhenjiang   (China)

Author keywords

Autophagy; Epithelial to mesenchymal transition; HIF 1 ; Pancreatic cancer stem cell

Indexed keywords

BECLIN; BECLIN 1; CD133 ANTIGEN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MEMBRANE PROTEIN; NERVE CELL ADHESION MOLECULE; PROTEIN LC3 II; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; GLYCOPROTEIN; HIF1A PROTEIN, HUMAN; LEUKOCYTE ANTIGEN; PEPTIDE;

ARTICLE; AUTOPHAGY; BXPC 3 CELL LINE; CANCER STEM CELL; CARCINOGENESIS; CELL MIGRATION; CONTROLLED STUDY; DRUG TARGETING; EPITHELIAL MESENCHYMAL TRANSITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INTERMITTENT HYPOXIA; METASTASIS INHIBITION; METASTASIS POTENTIAL; PANC 1 CELL LINE; PANCREAS CANCER; PANCREATIC CANCER CELL LINE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; TUMOR INVASION; WESTERN BLOTTING; CELL HYPOXIA; CELL MOTION; METABOLISM; METASTASIS; PANCREAS TUMOR; PATHOLOGY; TUMOR CELL LINE; UPREGULATION;

ANTIGENS, CD; AUTOPHAGY; CELL HYPOXIA; CELL LINE, TUMOR; CELL MOVEMENT; EPITHELIAL-MESENCHYMAL TRANSITION; GLYCOPROTEINS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; NEOPLASM METASTASIS; NEOPLASTIC STEM CELLS; PANCREATIC NEOPLASMS; PEPTIDES; UP-REGULATION;

EID: 84920759332     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2014.3298     Document Type: Article

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