메뉴 건너뛰기




Volumn 81, Issue 2, 2015, Pages 481-491

Immunoprecipitation of native botulinum neurotoxin complexes from Clostridium botulinum subtype A strains

Author keywords

[No Author keywords available]

Indexed keywords

CLOSTRIDIUM; DNA; POTASSIUM COMPOUNDS; SODIUM CHLORIDE; STRAIN;

EID: 84920742553     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.02817-14     Document Type: Article
Times cited : (10)

References (64)
  • 2
    • 0023664001 scopus 로고
    • Role of the heavy and light chains of botulinum neurotoxin in neuromuscular paralysis
    • Bandyopadhyay S, Clark AW, DasGupta BR, Sathyamoorthy V. 1987. Role of the heavy and light chains of botulinum neurotoxin in neuromuscular paralysis. J Biol Chem 262:2660-2663.
    • (1987) J Biol Chem , vol.262 , pp. 2660-2663
    • Bandyopadhyay, S.1    Clark, A.W.2    DasGupta, B.R.3    Sathyamoorthy, V.4
  • 3
    • 0033520494 scopus 로고    scopus 로고
    • Sequence homology and structural analysis of the clostridial neurotoxins
    • Lacy DB, Stevens RC. 1999. Sequence homology and structural analysis of the clostridial neurotoxins. J Mol Biol 291:1091-1104. http://dx.doi.org /10.1006/jmbi.1999.2945.
    • (1999) J Mol Biol , vol.291 , pp. 1091-1104
    • Lacy, D.B.1    Stevens, R.C.2
  • 4
    • 0031712779 scopus 로고    scopus 로고
    • Crystal structure of botulinum neurotoxin type A and implications for toxicity
    • Lacy DB, Tepp W, Cohen AC, DasGupta BR, Stevens RC. 1998. Crystal structure of botulinum neurotoxin type A and implications for toxicity. Nat Struct Biol 5:898-902. http://dx.doi.org/10.1038/2338.
    • (1998) Nat Struct Biol , vol.5 , pp. 898-902
    • Lacy, D.B.1    Tepp, W.2    Cohen, A.C.3    DasGupta, B.R.4    Stevens, R.C.5
  • 5
    • 84891543590 scopus 로고    scopus 로고
    • A novel strain of Clostridium botulinum that produces type B and type H botulinum toxins
    • Barash JR, Arnon SS. 2014. A novel strain of Clostridium botulinum that produces type B and type H botulinum toxins. J Infect Dis 209:183-191. http://dx.doi.org/10.1093/infdis/jit449.
    • (2014) J Infect Dis , vol.209 , pp. 183-191
    • Barash, J.R.1    Arnon, S.S.2
  • 6
    • 0842348390 scopus 로고    scopus 로고
    • Pharmacology and immunology of botulinum toxin type A
    • Aoki KR. 2003. Pharmacology and immunology of botulinum toxin type A. Clin Dermatol 21:476-480. http://dx.doi.org/10.1016/j.clindermatol.2003.11.006.
    • (2003) Clin Dermatol , vol.21 , pp. 476-480
    • Aoki, K.R.1
  • 7
    • 0642346854 scopus 로고    scopus 로고
    • Botulinum neurotoxin type A
    • Delgado MR. 2003. Botulinum neurotoxin type A. J Am Acad Orthop Surg 11:291-294.
    • (2003) J Am Acad Orthop Surg , vol.11 , pp. 291-294
    • Delgado, M.R.1
  • 9
    • 67650045501 scopus 로고    scopus 로고
    • Novel Clostridium botulinum toxin gene arrangement with subtype A5 and partial subtype B3 botulinum neurotoxin genes
    • Dover N, Barash JR, Arnon SS. 2009. Novel Clostridium botulinum toxin gene arrangement with subtype A5 and partial subtype B3 botulinum neurotoxin genes. J Clin Microbiol 47:2349-2350. http://dx.doi.org/10 .1128/JCM.00799-09.
    • (2009) J Clin Microbiol , vol.47 , pp. 2349-2350
    • Dover, N.1    Barash, J.R.2    Arnon, S.S.3
  • 10
  • 11
    • 79960085306 scopus 로고    scopus 로고
    • Purification, modeling, and analysis of botulinum neurotoxin subtype A5 (BoNT/A5) from Clostridium botulinum strain A661222
    • Jacobson MJ, Lin G, Tepp W, Dupuy J, Stenmark P, Stevens RC, Johnson EA. 2011. Purification, modeling, and analysis of botulinum neurotoxin subtype A5 (BoNT/A5) from Clostridium botulinum strain A661222. Appl Environ Microbiol 77:4217-4222. http://dx.doi.org/10 .1128/AEM.00201-11.
    • (2011) Appl Environ Microbiol , vol.77 , pp. 4217-4222
    • Jacobson, M.J.1    Lin, G.2    Tepp, W.3    Dupuy, J.4    Stenmark, P.5    Stevens, R.C.6    Johnson, E.A.7
  • 12
    • 76149138491 scopus 로고    scopus 로고
    • Expression of the Clostridium botulinum A2 neurotoxin gene cluster proteins and characterization of the A2 complex
    • Lin G, Tepp WH, Pier CL, Jacobson MJ, Johnson EA. 2010. Expression of the Clostridium botulinum A2 neurotoxin gene cluster proteins and characterization of the A2 complex. Appl Environ Microbiol 76:40-47. http://dx.doi.org/10.1128/AEM.01882-09.
    • (2010) Appl Environ Microbiol , vol.76 , pp. 40-47
    • Lin, G.1    Tepp, W.H.2    Pier, C.L.3    Jacobson, M.J.4    Johnson, E.A.5
  • 13
    • 84861165932 scopus 로고    scopus 로고
    • Purification and characterization of a novel subtype A3 botulinum neurotoxin
    • Tepp WH, Lin G, Johnson EA. 2012. Purification and characterization of a novel subtype A3 botulinum neurotoxin. Appl Environ Microbiol 78: 3108-3113. http://dx.doi.org/10.1128/AEM.07967-11.
    • (2012) Appl Environ Microbiol , vol.78 , pp. 3108-3113
    • Tepp, W.H.1    Lin, G.2    Johnson, E.A.3
  • 14
    • 84884384897 scopus 로고    scopus 로고
    • Characterization of botulinum neurotoxin A subtypes 1 through 5 by investigation of activities in mice, in neuronal cell cultures, and in vitro
    • Whitemarsh RC, Tepp WH, Bradshaw M, Lin G, Pier CL, Scherf JM, Johnson EA, Pellett S. 2013. Characterization of botulinum neurotoxin A subtypes 1 through 5 by investigation of activities in mice, in neuronal cell cultures, and in vitro. Infect Immun 81:3894-3902. http://dx.doi.org/10 .1128/IAI.00536-13.
    • (2013) Infect Immun , vol.81 , pp. 3894-3902
    • Whitemarsh, R.C.1    Tepp, W.H.2    Bradshaw, M.3    Lin, G.4    Pier, C.L.5    Scherf, J.M.6    Johnson, E.A.7    Pellett, S.8
  • 15
    • 84910107318 scopus 로고    scopus 로고
    • Holotoxin activity of botulinum neurotoxin subtype A4 originating from a nontoxigenic Clostridium botulinum expression system
    • Bradshaw M, Tepp WH, Whitemarsh RCM, Pellett S, Johnson EA. 2014. Holotoxin activity of botulinum neurotoxin subtype A4 originating from a nontoxigenic Clostridium botulinum expression system. Appl Environ Microbiol 80:7415-7422. http://dx.doi.org/10.1128/AEM.01795-14.
    • (2014) Appl Environ Microbiol , vol.80 , pp. 7415-7422
    • Bradshaw, M.1    Tepp, W.H.2    Whitemarsh, R.C.M.3    Pellett, S.4    Johnson, E.A.5
  • 16
    • 70349427106 scopus 로고    scopus 로고
    • Neurotoxin gene clusters in Clostridium botulinum type Ab strains
    • Luquez C, Raphael BH, Maslanka SE. 2009. Neurotoxin gene clusters in Clostridium botulinum type Ab strains. Appl Environ Microbiol 75:6094- 6101. http://dx.doi.org/10.1128/AEM.01009-09.
    • (2009) Appl Environ Microbiol , vol.75 , pp. 6094-6101
    • Luquez, C.1    Raphael, B.H.2    Maslanka, S.E.3
  • 17
    • 84869205627 scopus 로고    scopus 로고
    • Toxin detection in patients' sera by mass spectrometry during two outbreaks of type A botulism in France
    • Mazuet C, Ezan E, Volland H, Popoff MR, Becher F. 2012. Toxin detection in patients' sera by mass spectrometry during two outbreaks of type A botulism in France. J Clin Microbiol 50:4091-4094. http://dx.doi .org/10.1128/JCM.02392-12.
    • (2012) J Clin Microbiol , vol.50 , pp. 4091-4094
    • Mazuet, C.1    Ezan, E.2    Volland, H.3    Popoff, M.R.4    Becher, F.5
  • 18
    • 0000623142 scopus 로고
    • The purification and crystallization of Clostridium botulinum type A toxin
    • Lamanna C, McElroy OE, Eklund HW. 1946. The purification and crystallization of Clostridium botulinum type A toxin. Science 103:613- 614. http://dx.doi.org/10.1126/science.103.2681.613.
    • (1946) Science , vol.103 , pp. 613-614
    • Lamanna, C.1    McElroy, O.E.2    Eklund, H.W.3
  • 19
    • 0003985298 scopus 로고
    • The lack of identity between hemagglutinin and the toxin of type A botulinal organism
    • Lamanna C, Lowenthal JP. 1951. The lack of identity between hemagglutinin and the toxin of type A botulinal organism. J Bacteriol 61:751-752.
    • (1951) J Bacteriol , vol.61 , pp. 751-752
    • Lamanna, C.1    Lowenthal, J.P.2
  • 20
    • 79955888195 scopus 로고
    • Studies on botulinus toxin. 2. Further purification by adsorption on colloids.
    • Sommer H, Snipe PT. 1928. Studies on botulinus toxin. 2. Further purification by adsorption on colloids. J Infect Dis 43:145-151.
    • (1928) J Infect Dis , vol.43 , pp. 145-151
    • Sommer, H.1    Snipe, P.T.2
  • 21
    • 0026548114 scopus 로고
    • Properties and use of botulinum toxin and other microbial neurotoxins in medicine
    • Schantz EJ, Johnson EA. 1992. Properties and use of botulinum toxin and other microbial neurotoxins in medicine. Microbiol Rev 56:80-99.
    • (1992) Microbiol Rev , vol.56 , pp. 80-99
    • Schantz, E.J.1    Johnson, E.A.2
  • 22
    • 0001371009 scopus 로고
    • Diffusion measurements in agar gel
    • Schantz EJ, Lauffer MA. 1962. Diffusion measurements in agar gel. Biochemistry 1:658-663. http://dx.doi.org/10.1021/bi00910a019.
    • (1962) Biochemistry , vol.1 , pp. 658-663
    • Schantz, E.J.1    Lauffer, M.A.2
  • 23
    • 0019161371 scopus 로고
    • Clostridium botulinum neurotoxin
    • Sugiyama H. 1980. Clostridium botulinum neurotoxin. Microbiol Rev 44:419-448.
    • (1980) Microbiol Rev , vol.44 , pp. 419-448
    • Sugiyama, H.1
  • 24
    • 0014690770 scopus 로고
    • Isolation and characterization of Clostridium botulinum type B toxin
    • Beers WH, Reich E. 1969. Isolation and characterization of Clostridium botulinum type B toxin. J Biol Chem 244:4473-4479.
    • (1969) J Biol Chem , vol.244 , pp. 4473-4479
    • Beers, W.H.1    Reich, E.2
  • 25
    • 0014435297 scopus 로고
    • Isolation of chromatographically pure toxin of Clostridium botulinum type B
    • DasGupta BR, Boroff DA, Cheong K. 1968. Isolation of chromatographically pure toxin of Clostridium botulinum type B. Biochem Biophys Res Commun 32:1057-1063. http://dx.doi.org/10.1016 /0006-291X(68)90137-X.
    • (1968) Biochem Biophys Res Commun , vol.32 , pp. 1057-1063
    • DasGupta, B.R.1    Boroff, D.A.2    Cheong, K.3
  • 26
    • 8844262587 scopus 로고    scopus 로고
    • Regulation of neurotoxin complex expression in Clostridium botulinum strains 62A, Hall A-hyper, and NCTC 2916
    • Bradshaw M, Dineen SS, Maks ND, Johnson EA. 2004. Regulation of neurotoxin complex expression in Clostridium botulinum strains 62A, Hall A-hyper, and NCTC 2916. Anaerobe 10:321-333. http://dx.doi.org /10.1016/j.anaerobe.2004.07.001.
    • (2004) Anaerobe , vol.10 , pp. 321-333
    • Bradshaw, M.1    Dineen, S.S.2    Maks, N.D.3    Johnson, E.A.4
  • 27
    • 0031889897 scopus 로고    scopus 로고
    • Phylogeny and taxonomy of the food-borne pathogen Clostridium botulinum and its neurotoxins
    • Collins MD, East AK. 1998. Phylogeny and taxonomy of the food-borne pathogen Clostridium botulinum and its neurotoxins. J Appl Microbiol 84:5-17. http://dx.doi.org/10.1046/j.1365-2672.1997.00313.x.
    • (1998) J Appl Microbiol , vol.84 , pp. 5-17
    • Collins, M.D.1    East, A.K.2
  • 28
    • 0032518928 scopus 로고    scopus 로고
    • Gene arrangement in the upstream region of Clostridium botulinum type E and Clostridium butyricum BL6340 progenitor toxin genes is different from that of other types
    • Kubota T, Yonekura N, Hariya Y, Isogai E, Isogai H, Amano K, Fujii N. 1998. Gene arrangement in the upstream region of Clostridium botulinum type E and Clostridium butyricum BL6340 progenitor toxin genes is different from that of other types. FEMS Microbiol Lett 158:215-221. http://dx .doi.org/10.1111/j.1574-6968.1998.tb12823.x.
    • (1998) FEMS Microbiol Lett , vol.158 , pp. 215-221
    • Kubota, T.1    Yonekura, N.2    Hariya, Y.3    Isogai, E.4    Isogai, H.5    Amano, K.6    Fujii, N.7
  • 29
    • 43049133550 scopus 로고    scopus 로고
    • Analysis of neurotoxin cluster genes in Clostridium botulinum strains producing botulinum neurotoxin serotype A subtypes
    • Jacobson MJ, Lin G, Raphael B, Andreadis J, Johnson EA. 2008. Analysis of neurotoxin cluster genes in Clostridium botulinum strains producing botulinum neurotoxin serotype A subtypes. Appl Environ Microbiol 74: 2778-2786. http://dx.doi.org/10.1128/AEM.02828-07.
    • (2008) Appl Environ Microbiol , vol.74 , pp. 2778-2786
    • Jacobson, M.J.1    Lin, G.2    Raphael, B.3    Andreadis, J.4    Johnson, E.A.5
  • 30
    • 0038050739 scopus 로고    scopus 로고
    • Neurotoxin gene clusters in Clostridium botulinum type A strains: sequence comparison and evolutionary implications
    • Dineen SS, Bradshaw M, Johnson EA. 2003. Neurotoxin gene clusters in Clostridium botulinum type A strains: sequence comparison and evolutionary implications. Curr Microbiol 46:345-352. http://dx.doi.org/10 .1007/s00284-002-3851-1.
    • (2003) Curr Microbiol , vol.46 , pp. 345-352
    • Dineen, S.S.1    Bradshaw, M.2    Johnson, E.A.3
  • 31
    • 0029843635 scopus 로고    scopus 로고
    • Organization and phylogenetic interrelationships of genes encoding components of the botulinum toxin complex in proteolytic Clostridium botulinum types A, B, and F: evidence of chimeric sequences in the gene encoding the nontoxic nonhemagglutinin component
    • East AK, Bhandari M, Stacey JM, Campbell KD, Collins MD. 1996. Organization and phylogenetic interrelationships of genes encoding components of the botulinum toxin complex in proteolytic Clostridium botulinum types A, B, and F: evidence of chimeric sequences in the gene encoding the nontoxic nonhemagglutinin component. Int J Syst Bacteriol 46:1105-1112.
    • (1996) Int J Syst Bacteriol , vol.46 , pp. 1105-1112
    • East, A.K.1    Bhandari, M.2    Stacey, J.M.3    Campbell, K.D.4    Collins, M.D.5
  • 32
    • 33745698456 scopus 로고    scopus 로고
    • A novel type A2 neurotoxin gene cluster in Clostridium botulinum strain Mascarpone
    • Franciosa G, Maugliani A, Floridi F, Aureli P. 2006. A novel type A2 neurotoxin gene cluster in Clostridium botulinum strain Mascarpone. FEMS Microbiol Lett 261:88-94. http://dx.doi.org/10.1111/j.1574-6968 .2006.00331.x.
    • (2006) FEMS Microbiol Lett , vol.261 , pp. 88-94
    • Franciosa, G.1    Maugliani, A.2    Floridi, F.3    Aureli, P.4
  • 33
  • 35
    • 77952239763 scopus 로고    scopus 로고
    • Detection and differentiation of Clostridium botulinum type A strains using a focusedDNAmicroarray
    • Raphael BH, Joseph LA, McCroskey LM, Luquez C, Maslanka SE. 2010. Detection and differentiation of Clostridium botulinum type A strains using a focusedDNAmicroarray. Mol Cell Probes 24:146-153. http://dx.doi .org/10.1016/j.mcp.2009.12.003.
    • (2010) Mol Cell Probes , vol.24 , pp. 146-153
    • Raphael, B.H.1    Joseph, L.A.2    McCroskey, L.M.3    Luquez, C.4    Maslanka, S.E.5
  • 36
    • 84875806832 scopus 로고    scopus 로고
    • Genetic diversity within Clostridium botulinum serotypes, botulinum neurotoxin gene clusters and toxin subtypes
    • Hill KK, Smith TJ. 2013. Genetic diversity within Clostridium botulinum serotypes, botulinum neurotoxin gene clusters and toxin subtypes. Curr Top Microbiol Immunol 364:1-20. http://dx.doi.org/10.1007/978-3-642 -33570-9_1.
    • (2013) Curr Top Microbiol Immunol , vol.364 , pp. 1-20
    • Hill, K.K.1    Smith, T.J.2
  • 37
    • 47049126863 scopus 로고    scopus 로고
    • Molecular properties of each subcomponent in Clostridium botulinum type B haemagglutinin complex
    • Arimitsu H, Sakaguchi Y, Lee JC, Ochi S, Tsukamoto K, Yamamoto Y, Ma S, Tsuji T, Oguma K. 2008. Molecular properties of each subcomponent in Clostridium botulinum type B haemagglutinin complex. Microb Pathog 45:142-149. http://dx.doi.org/10.1016/j.micpath.2008.04.007.
    • (2008) Microb Pathog , vol.45 , pp. 142-149
    • Arimitsu, H.1    Sakaguchi, Y.2    Lee, J.C.3    Ochi, S.4    Tsukamoto, K.5    Yamamoto, Y.6    Ma, S.7    Tsuji, T.8    Oguma, K.9
  • 40
    • 0017378439 scopus 로고
    • Intestinal absorption of botulinum toxins of different molecular sizes in rats
    • Sugii S, Ohishi I, Sakaguchi G. 1977. Intestinal absorption of botulinum toxins of different molecular sizes in rats. Infect Immun 17:491-496.
    • (1977) Infect Immun , vol.17 , pp. 491-496
    • Sugii, S.1    Ohishi, I.2    Sakaguchi, G.3
  • 41
    • 0031435919 scopus 로고    scopus 로고
    • The haemagglutinin of Clostridium botulinum type C progenitor toxin plays an essential role in binding of toxin to the epithelial cells of guinea pig small intestine, leading to the efficient absorption of the toxin
    • Fujinaga Y, Inoue K, Watanabe S, Yokota K, Hirai Y, Nagamachi E, Oguma K. 1997. The haemagglutinin of Clostridium botulinum type C progenitor toxin plays an essential role in binding of toxin to the epithelial cells of guinea pig small intestine, leading to the efficient absorption of the toxin. Microbiology 143:3841-3847. http://dx.doi.org/10.1099/00221287 -143-12-3841.
    • (1997) Microbiology , vol.143 , pp. 3841-3847
    • Fujinaga, Y.1    Inoue, K.2    Watanabe, S.3    Yokota, K.4    Hirai, Y.5    Nagamachi, E.6    Oguma, K.7
  • 44
    • 79959824749 scopus 로고    scopus 로고
    • Molecular diversity of the two sugarbinding sites of the beta-trefoil lectin HA33/C (HA1) from Clostridium botulinum type C neurotoxin
    • Nakamura T, Tonozuka T, Ito S, Takeda Y, Sato R, Matsuo I, Ito Y, Oguma K, Nishikawa A. 2011. Molecular diversity of the two sugarbinding sites of the beta-trefoil lectin HA33/C (HA1) from Clostridium botulinum type C neurotoxin. Arch Biochem Biophys 512:69-77. http: //dx.doi.org/10.1016/j.abb.2011.05.012.
    • (2011) Arch Biochem Biophys , vol.512 , pp. 69-77
    • Nakamura, T.1    Tonozuka, T.2    Ito, S.3    Takeda, Y.4    Sato, R.5    Matsuo, I.6    Ito, Y.7    Oguma, K.8    Nishikawa, A.9
  • 46
    • 84881376324 scopus 로고    scopus 로고
    • Transport of the botulinum neurotoxin-associating protein, nontoxic nonhemagglutinin, across the rat small intestinal epithelial cell monolayer
    • Miyashita S, Sagane Y, Niwa K, Watanabe T. 2013. Transport of the botulinum neurotoxin-associating protein, nontoxic nonhemagglutinin, across the rat small intestinal epithelial cell monolayer. FEMS Microbiol Lett 346:73-80. http://dx.doi.org/10.1111/1574-6968.12205.
    • (2013) FEMS Microbiol Lett , vol.346 , pp. 73-80
    • Miyashita, S.1    Sagane, Y.2    Niwa, K.3    Watanabe, T.4
  • 47
    • 84878526283 scopus 로고    scopus 로고
    • Molecular composition and extinction coefficient of native botulinum neurotoxin complex produced by Clostridium botulinum Hall A strain
    • Bryant AM, Davis J, Cai S, Singh BR. 2013. Molecular composition and extinction coefficient of native botulinum neurotoxin complex produced by Clostridium botulinum Hall A strain. Protein J 32:106-117. http://dx .doi.org/10.1007/s10930-013-9465-6.
    • (2013) Protein J , vol.32 , pp. 106-117
    • Bryant, A.M.1    Davis, J.2    Cai, S.3    Singh, B.R.4
  • 48
    • 84864287475 scopus 로고    scopus 로고
    • Carbohydrate recognition mechanism of HA70 from Clostridium botulinum deduced from X-ray structures in complexes with sialylated oligosaccharides
    • Yamashita S, Yoshida H, Uchiyama N, Nakakita Y, Nakakita S, Tonozuka T, Oguma K, Nishikawa A, Kamitori S. 2012. Carbohydrate recognition mechanism of HA70 from Clostridium botulinum deduced from X-ray structures in complexes with sialylated oligosaccharides. FEBS Lett 586:2404-2410. http://dx.doi.org/10.1016/j.febslet.2012.05.055.
    • (2012) FEBS Lett , vol.586 , pp. 2404-2410
    • Yamashita, S.1    Yoshida, H.2    Uchiyama, N.3    Nakakita, Y.4    Nakakita, S.5    Tonozuka, T.6    Oguma, K.7    Nishikawa, A.8    Kamitori, S.9
  • 50
  • 51
    • 84875809344 scopus 로고    scopus 로고
    • Assembly and function of the botulinum neurotoxin progenitor complex
    • Gu S, Jin R. 2013. Assembly and function of the botulinum neurotoxin progenitor complex. Curr Top Microbiol Immunol 364:21-44. http://dx .doi.org/10.1007/978-3-642-33570-9_2.
    • (2013) Curr Top Microbiol Immunol , vol.364 , pp. 21-44
    • Gu, S.1    Jin, R.2
  • 52
    • 70949098601 scopus 로고    scopus 로고
    • Identification of protein- protein interactions with glutathione-S-transferase (GST) fusion proteins
    • Einarson MB, Pugacheva EN, Orlinick JR. 2007. Identification of protein- protein interactions with glutathione-S-transferase (GST) fusion proteins. CSH Protoc http://dx.doi.org/10.1101/pdb.top11.
    • (2007) CSH Protoc
    • Einarson, M.B.1    Pugacheva, E.N.2    Orlinick, J.R.3
  • 53
    • 3242675407 scopus 로고    scopus 로고
    • Glutathione-S-transferase-fusion based assays for studying protein-protein interactions
    • Vikis HG, Guan KL. 2004. Glutathione-S-transferase-fusion based assays for studying protein-protein interactions. Methods Mol Biol 261:175-186.
    • (2004) Methods Mol Biol , vol.261 , pp. 175-186
    • Vikis, H.G.1    Guan, K.L.2
  • 54
    • 0028926048 scopus 로고
    • Protein-protein interactions: methods for detection and analysis
    • Phizicky EM, Fields S. 1995. Protein-protein interactions: methods for detection and analysis. Microbiol Rev 59:94-123.
    • (1995) Microbiol Rev , vol.59 , pp. 94-123
    • Phizicky, E.M.1    Fields, S.2
  • 55
    • 33845275018 scopus 로고    scopus 로고
    • RIP-Chip: the isolation and identification of mRNAs, microRNAs and protein components of ribonucleoprotein complexes from cell extracts
    • Keene JD, Komisarow JM, Friedersdorf MB. 2006. RIP-Chip: the isolation and identification of mRNAs, microRNAs and protein components of ribonucleoprotein complexes from cell extracts. Nat Protoc 1:302-307. http://dx.doi.org/10.1038/nprot.2006.47.
    • (2006) Nat Protoc , vol.1 , pp. 302-307
    • Keene, J.D.1    Komisarow, J.M.2    Friedersdorf, M.B.3
  • 57
    • 0021128925 scopus 로고
    • Purification and amino acid composition of type A botulinum neurotoxin
    • DasGupta BR, Sathyamoorthy V. 1984. Purification and amino acid composition of type A botulinum neurotoxin. Toxicon 22:415-424. http: //dx.doi.org/10.1016/0041-0101(84)90085-0.
    • (1984) Toxicon , vol.22 , pp. 415-424
    • DasGupta, B.R.1    Sathyamoorthy, V.2
  • 58
    • 0021062225 scopus 로고
    • Identification of strain B 657 of Clostridium botulinum
    • Gimenez DF, Gimenez JA. 1983. Identification of strain B 657 of Clostridium botulinum. Rev Argent Microbiol 15:51-55.
    • (1983) Rev Argent Microbiol , vol.15 , pp. 51-55
    • Gimenez, D.F.1    Gimenez, J.A.2
  • 60
    • 15844377448 scopus 로고    scopus 로고
    • Genetic characterization of Clostridium botulinum type A containing silent type B neurotoxin gene sequences
    • Hutson RA, Zhou Y, Collins MD, Johnson EA, Hatheway CL, Sugiyama H. 1996. Genetic characterization of Clostridium botulinum type A containing silent type B neurotoxin gene sequences. J Biol Chem 271:10786- 10792. http://dx.doi.org/10.1074/jbc.271.18.10786.
    • (1996) J Biol Chem , vol.271 , pp. 10786-10792
    • Hutson, R.A.1    Zhou, Y.2    Collins, M.D.3    Johnson, E.A.4    Hatheway, C.L.5    Sugiyama, H.6
  • 61
    • 0028283313 scopus 로고
    • Organization of the botulinum neurotoxin C1 gene and its associated non-toxic protein genes in Clostridium botulinum C 468
    • Hauser D, Eklund MW, Boquet P, Popoff MR. 1994. Organization of the botulinum neurotoxin C1 gene and its associated non-toxic protein genes in Clostridium botulinum C 468. Mol Gen Genet 243:631-640.
    • (1994) Mol Gen Genet , vol.243 , pp. 631-640
    • Hauser, D.1    Eklund, M.W.2    Boquet, P.3    Popoff, M.R.4
  • 62
    • 84880606412 scopus 로고    scopus 로고
    • Comparative immunochemical characteristics of botulinum neurotoxin typeAand its associated proteins
    • Bryant AM, Cai S, Singh BR. 2013. Comparative immunochemical characteristics of botulinum neurotoxin typeAand its associated proteins. Toxicon 72:126-132. http://dx.doi.org/10.1016/j.toxicon.2013.06.011.
    • (2013) Toxicon , vol.72 , pp. 126-132
    • Bryant, A.M.1    Cai, S.2    Singh, B.R.3
  • 64
    • 79952364126 scopus 로고    scopus 로고
    • Studies on the dissociation of botulinum neurotoxin type A complexes
    • Eisele KH, Fink K, Vey M, Taylor HV. 2011. Studies on the dissociation of botulinum neurotoxin type A complexes. Toxicon 57:555-565. http: //dx.doi.org/10.1016/j.toxicon.2010.12.019.
    • (2011) Toxicon , vol.57 , pp. 555-565
    • Eisele, K.H.1    Fink, K.2    Vey, M.3    Taylor, H.V.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.