메뉴 건너뛰기




Volumn 81, Issue 10, 2013, Pages 3894-3902

Characterization of botulinum neurotoxin A subtypes 1 through 5 by investigation of activities in mice, in neuronal cell cultures, and in vitro

Author keywords

[No Author keywords available]

Indexed keywords

BOTULINUM TOXIN A;

EID: 84884384897     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00536-13     Document Type: Article
Times cited : (102)

References (53)
  • 1
    • 67649279877 scopus 로고    scopus 로고
    • Biology and genomic analysis of Clostridium botulinum
    • 320
    • PeckMW.2009. Biology and genomic analysis of Clostridium botulinum. Adv. Microb. Physiol. 55:183-265, 320.
    • (2009) Adv. Microb. Physiol. , vol.55 , pp. 183-265
    • Peck, M.W.1
  • 2
    • 84875806832 scopus 로고    scopus 로고
    • Genetic diversity within Clostridium botulinum serotypes, botulinum neurotoxin gene clusters and toxin subtypes
    • Hill KK, Smith TJ. 2013. Genetic diversity within Clostridium botulinum serotypes, botulinum neurotoxin gene clusters and toxin subtypes. Curr. Top. Microbiol. Immunol. 364:1-20.
    • (2013) Curr. Top. Microbiol. Immunol. , vol.364 , pp. 1-20
    • Hill, K.K.1    Smith, T.J.2
  • 4
    • 77953642001 scopus 로고    scopus 로고
    • Botulinum neurotoxin: a marvel of protein design
    • Montal M. 2010. Botulinum neurotoxin: a marvel of protein design. Annu. Rev. Biochem. 79:591-617.
    • (2010) Annu. Rev. Biochem. , vol.79 , pp. 591-617
    • Montal, M.1
  • 5
    • 0028310404 scopus 로고
    • Mechanism of action of tetanus and botulinum neurotoxins
    • Montecucco C, Schiavo G. 1994. Mechanism of action of tetanus and botulinum neurotoxins. Mol. Microbiol. 13:1-8.
    • (1994) Mol. Microbiol. , vol.13 , pp. 1-8
    • Montecucco, C.1    Schiavo, G.2
  • 8
    • 77956293758 scopus 로고    scopus 로고
    • An update on the neurologic applications of botulinum toxins
    • Evidente VG, Adler CH. 2010. An update on the neurologic applications of botulinum toxins. Curr. Neurol. Neurosci. Rep. 10:338-344.
    • (2010) Curr. Neurol. Neurosci. Rep. , vol.10 , pp. 338-344
    • Evidente, V.G.1    Adler, C.H.2
  • 9
    • 70449584743 scopus 로고    scopus 로고
    • Current clinical applications of botulinum toxin
    • Truong DD, Stenner A, Reichel G. 2009. Current clinical applications of botulinum toxin. Curr. Pharm. Des. 15:3671-3680.
    • (2009) Curr. Pharm. Des. , vol.15 , pp. 3671-3680
    • Truong, D.D.1    Stenner, A.2    Reichel, G.3
  • 10
    • 0026548114 scopus 로고
    • Properties and use of botulinum toxin and other microbial neurotoxins in medicine
    • Schantz EJ, Johnson EA. 1992. Properties and use of botulinum toxin and other microbial neurotoxins in medicine. Microbiol. Rev. 56:80-99.
    • (1992) Microbiol. Rev. , vol.56 , pp. 80-99
    • Schantz, E.J.1    Johnson, E.A.2
  • 11
    • 84864065068 scopus 로고    scopus 로고
    • Clinical applications of botulinum toxin
    • Dressler D. 2012. Clinical applications of botulinum toxin. Curr. Opin. Microbiol. 15:325-336.
    • (2012) Curr. Opin. Microbiol. , vol.15 , pp. 325-336
    • Dressler, D.1
  • 12
    • 0018901429 scopus 로고
    • Botulinum toxin injection into extraocular muscles as an alternative to strabismus surgery
    • Scott AB. 1980. Botulinum toxin injection into extraocular muscles as an alternative to strabismus surgery. J. Pediatr. Ophthalmol. Strabismus 17: 21-25.
    • (1980) J. Pediatr. Ophthalmol. Strabismus , vol.17 , pp. 21-25
    • Scott, A.B.1
  • 13
    • 0038050739 scopus 로고    scopus 로고
    • Neurotoxin gene clusters in Clostridium botulinum type A strains: sequence comparison and evolutionary implications
    • Dineen SS, Bradshaw M, Johnson EA. 2003. Neurotoxin gene clusters in Clostridium botulinum type A strains: sequence comparison and evolutionary implications. Curr. Microbiol. 46:345-352.
    • (2003) Curr. Microbiol. , vol.46 , pp. 345-352
    • Dineen, S.S.1    Bradshaw, M.2    Johnson, E.A.3
  • 14
    • 0027379492 scopus 로고
    • Sequence of the gene coding for the neurotoxin of Clostridium botulinum type A associated with infant botulism: comparison with other clostridial neurotoxins
    • Willems A, East AK, Lawson PA, Collins MD. 1993. Sequence of the gene coding for the neurotoxin of Clostridium botulinum type A associated with infant botulism: comparison with other clostridial neurotoxins. Res. Microbiol. 144:547-556.
    • (1993) Res. Microbiol. , vol.144 , pp. 547-556
    • Willems, A.1    East, A.K.2    Lawson, P.A.3    Collins, M.D.4
  • 16
    • 67650045501 scopus 로고    scopus 로고
    • Novel Clostridium botulinum toxin gene arrangement with subtype A5 and partial subtype B3 botulinum neurotoxin genes
    • Dover N, Barash JR, Arnon SS. 2009. Novel Clostridium botulinum toxin gene arrangement with subtype A5 and partial subtype B3 botulinum neurotoxin genes. J. Clin. Microbiol. 47:2349-2350.
    • (2009) J. Clin. Microbiol. , vol.47 , pp. 2349-2350
    • Dover, N.1    Barash, J.R.2    Arnon, S.S.3
  • 17
    • 70349427106 scopus 로고    scopus 로고
    • Neurotoxin gene clusters in Clostridium botulinum type Ab strains
    • Lúquez C, Raphael BH, Maslanka SE. 2009. Neurotoxin gene clusters in Clostridium botulinum type Ab strains. Appl. Environ. Microbiol. 75: 6094-6101.
    • (2009) Appl. Environ. Microbiol. , vol.75 , pp. 6094-6101
    • Lúquez, C.1    Raphael, B.H.2    Maslanka, S.E.3
  • 18
    • 84869205627 scopus 로고    scopus 로고
    • Toxin detection in patients' sera by mass spectrometry during two outbreaks of type A botulism in France
    • Mazuet C, Ezan E, Volland H, PopoffMR, Becher F. 2012. Toxin detection in patients' sera by mass spectrometry during two outbreaks of type A botulism in France. J. Clin. Microbiol. 50:4091-4094.
    • (2012) J. Clin. Microbiol. , vol.50 , pp. 4091-4094
    • Mazuet, C.1    Ezan, E.2    Volland, H.3    Popoff, M.R.4    Becher, F.5
  • 22
    • 84855677807 scopus 로고    scopus 로고
    • Type A1 but not type A2 botulinum toxin decreases the grip strength of the contralateral foreleg through axonal transport from the toxin-treated foreleg of rats
    • Torii Y, Akaike N, Harakawa T, Kato K, Sugimoto N, Goto Y, Nakahira S, Kohda T, Kozaki S, Kaji R, Ginnaga A. 2011. Type A1 but not type A2 botulinum toxin decreases the grip strength of the contralateral foreleg through axonal transport from the toxin-treated foreleg of rats. J. Pharmacol. Sci. 117:275-285.
    • (2011) J. Pharmacol. Sci. , vol.117 , pp. 275-285
    • Torii, Y.1    Akaike, N.2    Harakawa, T.3    Kato, K.4    Sugimoto, N.5    Goto, Y.6    Nakahira, S.7    Kohda, T.8    Kozaki, S.9    Kaji, R.10    Ginnaga, A.11
  • 23
    • 84861165932 scopus 로고    scopus 로고
    • Purification and characterization of a novel subtype a3 botulinum neurotoxin
    • Tepp WH, Lin G, Johnson EA. 2012. Purification and characterization of a novel subtype a3 botulinum neurotoxin. Appl. Environ. Microbiol. 78: 3108-3113.
    • (2012) Appl. Environ. Microbiol. , vol.78 , pp. 3108-3113
    • Tepp, W.H.1    Lin, G.2    Johnson, E.A.3
  • 24
  • 25
    • 65449127764 scopus 로고    scopus 로고
    • Extraction and inhibition of enzymatic activity of botulinum neurotoxins/A1,/A2, and/A3 by a panel of monoclonal anti-BoNT/A antibodies
    • doi:10.1371/journal.pone.0005355
    • Kalb SR, Lou J, Garcia-Rodriguez C, Geren IN, Smith TJ, Moura H, Marks JD, Smith LA, Pirkle JL, Barr JR. 2009. Extraction and inhibition of enzymatic activity of botulinum neurotoxins/A1,/A2, and/A3 by a panel of monoclonal anti-BoNT/A antibodies. PLoS One 4:e5355. doi:10.1371/journal.pone.0005355.
    • (2009) PLoS One , vol.4
    • Kalb, S.R.1    Lou, J.2    Garcia-Rodriguez, C.3    Geren, I.N.4    Smith, T.J.5    Moura, H.6    Marks, J.D.7    Smith, L.A.8    Pirkle, J.L.9    Barr, J.R.10
  • 26
    • 77957879208 scopus 로고    scopus 로고
    • Characterization of botulinum neurotoxin type A neutralizing monoclonal antibodies and influence of their half-lives on therapeutic activity
    • doi:10.1371/journal.pone.0012416
    • Mazuet C, Dano J, PopoffMR, Creminon C, Volland H. 2010. Characterization of botulinum neurotoxin type A neutralizing monoclonal antibodies and influence of their half-lives on therapeutic activity. PLoS One 5:e12416. doi:10.1371/journal.pone.0012416.
    • (2010) PLoS One , vol.5
    • Mazuet, C.1    Dano, J.2    Popoff, M.R.3    Creminon, C.4    Volland, H.5
  • 28
    • 77952291365 scopus 로고    scopus 로고
    • Comparison of the primary rat spinal cord cell (RSC) assay and the mouse bioassay for botulinum neurotoxin type A potency determination
    • Pellett S, Tepp WH, Toth SI, Johnson EA. 2010. Comparison of the primary rat spinal cord cell (RSC) assay and the mouse bioassay for botulinum neurotoxin type A potency determination. J. Pharmacol. Toxicol. Methods 61:304-310.
    • (2010) J. Pharmacol. Toxicol. Methods , vol.61 , pp. 304-310
    • Pellett, S.1    Tepp, W.H.2    Toth, S.I.3    Johnson, E.A.4
  • 29
    • 84859017992 scopus 로고    scopus 로고
    • Novel application of human neurons derived from induced pluripotent stem cells for highly sensitive botulinum neurotoxin detection
    • Whitemarsh RC, Strathman MJ, Chase LG, Stankewicz C, Tepp WH, Johnson EA, Pellett S. 2012. Novel application of human neurons derived from induced pluripotent stem cells for highly sensitive botulinum neurotoxin detection. Toxicol. Sci. 126:426-435.
    • (2012) Toxicol. Sci. , vol.126 , pp. 426-435
    • Whitemarsh, R.C.1    Strathman, M.J.2    Chase, L.G.3    Stankewicz, C.4    Tepp, W.H.5    Johnson, E.A.6    Pellett, S.7
  • 30
    • 34948874826 scopus 로고    scopus 로고
    • A neuronal cell-based botulinum neurotoxin assay for highly sensitive and specific detection of neutralizing serum antibodies
    • Pellett S, Tepp WH, Clancy CM, Borodic GE, Johnson EA. 2007. A neuronal cell-based botulinum neurotoxin assay for highly sensitive and specific detection of neutralizing serum antibodies. FEBS Lett. 581:4803-4808.
    • (2007) FEBS Lett. , vol.581 , pp. 4803-4808
    • Pellett, S.1    Tepp, W.H.2    Clancy, C.M.3    Borodic, G.E.4    Johnson, E.A.5
  • 31
    • 0345832207 scopus 로고    scopus 로고
    • Uptake of botulinum neurotoxin into cultured neurons
    • Keller JE, Cai F, Neale EA. 2004. Uptake of botulinum neurotoxin into cultured neurons. Biochemistry 43:526-532.
    • (2004) Biochemistry , vol.43 , pp. 526-532
    • Keller, J.E.1    Cai, F.2    Neale, E.A.3
  • 33
    • 76149138491 scopus 로고    scopus 로고
    • Expression of the Clostridium botulinum A2 neurotoxin gene cluster proteins and characterization of the A2 complex
    • Lin G, Tepp WH, Pier CL, Jacobson MJ, Johnson EA. 2010. Expression of the Clostridium botulinum A2 neurotoxin gene cluster proteins and characterization of the A2 complex. Appl. Environ. Microbiol. 76:40-47.
    • (2010) Appl. Environ. Microbiol. , vol.76 , pp. 40-47
    • Lin, G.1    Tepp, W.H.2    Pier, C.L.3    Jacobson, M.J.4    Johnson, E.A.5
  • 34
    • 79960085306 scopus 로고    scopus 로고
    • Purification, modeling, and analysis of botulinum neurotoxin subtype A5 (BoNT/A5) from Clostridium botulinum strain A661222
    • Jacobson MJ, Lin G, Tepp W, Dupuy J, Stenmark P, Stevens RC, Johnson EA. 2011. Purification, modeling, and analysis of botulinum neurotoxin subtype A5 (BoNT/A5) from Clostridium botulinum strain A661222. Appl. Environ. Microbiol. 77:4217-4222.
    • (2011) Appl. Environ. Microbiol. , vol.77 , pp. 4217-4222
    • Jacobson, M.J.1    Lin, G.2    Tepp, W.3    Dupuy, J.4    Stenmark, P.5    Stevens, R.C.6    Johnson, E.A.7
  • 38
    • 33745158157 scopus 로고
    • A simple method of determining fifty per cent endpoints
    • Reed JL, Muench H. 1938. A simple method of determining fifty per cent endpoints. Am. J. Hyg. 27:493-497.
    • (1938) Am. J. Hyg. , vol.27 , pp. 493-497
    • Reed, J.L.1    Muench, H.2
  • 40
    • 6944237312 scopus 로고    scopus 로고
    • Using fluorescent sensors to detect botulinum neurotoxin activity in vitro and in living cells
    • Dong M, Tepp WH, Johnson EA, Chapman ER. 2004. Using fluorescent sensors to detect botulinum neurotoxin activity in vitro and in living cells. Proc. Natl. Acad. Sci. U. S. A. 101:14701-14706.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 14701-14706
    • Dong, M.1    Tepp, W.H.2    Johnson, E.A.3    Chapman, E.R.4
  • 41
    • 0032776446 scopus 로고    scopus 로고
    • Persistence of botulinum neurotoxin action in cultured spinal cord cells
    • Keller JE, Neale EA, Oyler G, Adler M. 1999. Persistence of botulinum neurotoxin action in cultured spinal cord cells. FEBS Lett. 456:137-142.
    • (1999) FEBS Lett. , vol.456 , pp. 137-142
    • Keller, J.E.1    Neale, E.A.2    Oyler, G.3    Adler, M.4
  • 43
    • 0033520494 scopus 로고    scopus 로고
    • Sequence homology and structural analysis of the clostridial neurotoxins
    • Lacy DB, Stevens RC. 1999. Sequence homology and structural analysis of the clostridial neurotoxins. J. Mol. Biol. 291:1091-1104.
    • (1999) J. Mol. Biol. , vol.291 , pp. 1091-1104
    • Lacy, D.B.1    Stevens, R.C.2
  • 44
    • 11144341950 scopus 로고    scopus 로고
    • Substrate recognition strategy for botulinum neurotoxin serotype A
    • Breidenbach MA, Brunger AT. 2004. Substrate recognition strategy for botulinum neurotoxin serotype A. Nature 432:925-929.
    • (2004) Nature , vol.432 , pp. 925-929
    • Breidenbach, M.A.1    Brunger, A.T.2
  • 46
    • 34250155247 scopus 로고    scopus 로고
    • Botulism diagnostics: from clinical symptoms to in vitro assays
    • Cai S, Singh BR, Sharma S. 2007. Botulism diagnostics: from clinical symptoms to in vitro assays. Crit. Rev. Microbiol. 33:109-125.
    • (2007) Crit. Rev. Microbiol. , vol.33 , pp. 109-125
    • Cai, S.1    Singh, B.R.2    Sharma, S.3
  • 47
    • 78650870674 scopus 로고    scopus 로고
    • Sensitive and quantitative detection of botulinum neurotoxin in neurons derived from mouse embryonic stem cells
    • Pellett S, Du ZW, Pier CL, Tepp WH, Zhang SC, Johnson EA. 2011. Sensitive and quantitative detection of botulinum neurotoxin in neurons derived from mouse embryonic stem cells. Biochem. Biophys. Res. Commun. 404:388-392.
    • (2011) Biochem. Biophys. Res. Commun. , vol.404 , pp. 388-392
    • Pellett, S.1    Du, Z.W.2    Pier, C.L.3    Tepp, W.H.4    Zhang, S.C.5    Johnson, E.A.6
  • 48
    • 84867857479 scopus 로고    scopus 로고
    • Model for studying Clostridium botulinum neurotoxin using differentiated motor neuron-like NG108-15 cells
    • Whitemarsh RC, Pier CL, Tepp WH, Pellett S, Johnson EA. 2012. Model for studying Clostridium botulinum neurotoxin using differentiated motor neuron-like NG108-15 cells. Biochem. Biophys. Res. Commun. 427:426-430.
    • (2012) Biochem. Biophys. Res. Commun. , vol.427 , pp. 426-430
    • Whitemarsh, R.C.1    Pier, C.L.2    Tepp, W.H.3    Pellett, S.4    Johnson, E.A.5
  • 49
    • 79551494442 scopus 로고    scopus 로고
    • Embryonic stem cell-derived neurons are a novel, highly sensitive tissue culture platform for botulinum research
    • McNutt P, Celver J, Hamilton T, Mesngon M. 2011. Embryonic stem cell-derived neurons are a novel, highly sensitive tissue culture platform for botulinum research. Biochem. Biophys. Res. Commun. 405:85-90.
    • (2011) Biochem. Biophys. Res. Commun. , vol.405 , pp. 85-90
    • McNutt, P.1    Celver, J.2    Hamilton, T.3    Mesngon, M.4
  • 50
    • 79955023053 scopus 로고    scopus 로고
    • Embryonic stem cell-derived motoneurons provide a highly sensitive cell culture model for botulinum neurotoxin studies, with implications for high-throughput drug discovery
    • Kiris E, Nuss JE, Burnett JC, Kota KP, Koh DC, Wanner LM, Torres-Melendez E, Gussio R, Tessarollo L, Bavari S. 2011. Embryonic stem cell-derived motoneurons provide a highly sensitive cell culture model for botulinum neurotoxin studies, with implications for high-throughput drug discovery. Stem Cell Res. 6:195-205.
    • (2011) Stem Cell Res. , vol.6 , pp. 195-205
    • Kiris, E.1    Nuss, J.E.2    Burnett, J.C.3    Kota, K.P.4    Koh, D.C.5    Wanner, L.M.6    Torres-Melendez, E.7    Gussio, R.8    Tessarollo, L.9    Bavari, S.10
  • 52
    • 84875811081 scopus 로고    scopus 로고
    • Progress in cell based assays for botulinum neurotoxin detection
    • Pellett S. 2013. Progress in cell based assays for botulinum neurotoxin detection. Curr. Top. Microbiol. Immunol. 364:257-285.
    • (2013) Curr. Top. Microbiol. Immunol. , vol.364 , pp. 257-285
    • Pellett, S.1
  • 53
    • 84869806437 scopus 로고    scopus 로고
    • Botulinum neurotoxin serotype A specific cell-based potency assay to replace the mouse bioassay
    • doi:10.1371/journal.pone.0049516
    • Fernández-Salas E, Wang J, Molina Y, Nelson JB, Jacky BP, Aoki KR. 2012. Botulinum neurotoxin serotype A specific cell-based potency assay to replace the mouse bioassay. PLoS One 7:e49516. doi:10.1371/journal.pone.0049516
    • (2012) PLoS One , vol.7
    • Fernández-Salas, E.1    Wang, J.2    Molina, Y.3    Nelson, J.B.4    Jacky, B.P.5    Aoki, K.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.