Single vs. swarm detection of microparticles and exosomes by flow cytometry

Journal of Thrombosis and Haemostasis

Volumn 10, Issue 5, 2012, Pages 919-930

  Van Der Pol, E ^a   Van Gemert, M J C ^a   Sturk, A ^a   Nieuwland, R ^a   Van Leeuwen, T G ^a,b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b UNIVERSITY OF TWENTE   (Netherlands)

Author keywords

Exosomes; Extracellular vesicles; Flow cytometry; Microparticles; Optical detection

Indexed keywords

BIOLOGICAL MARKER; POLYSTYRENE; SILICON DIOXIDE;

ARTICLE; COMPARATIVE STUDY; EXOSOME; FLOW CYTOMETRY; HUMAN; HUMAN CELL; ILLUMINATION; LASER; LIGHT SCATTERING; MEASUREMENT; MODEL; PRIORITY JOURNAL; REFRACTION INDEX; SIGNAL DETECTION; STANDARDIZATION;

CALIBRATION; CELL SIZE; CELL-DERIVED MICROPARTICLES; EXOSOMES; FLOW CYTOMETRY; HUMANS; LIGHT; LIMIT OF DETECTION; MALE; MODELS, THEORETICAL; ORGANELLE SIZE; PARTICLE SIZE; POLYSTYRENES; REPRODUCIBILITY OF RESULTS; SCATTERING, RADIATION; SIGNAL PROCESSING, COMPUTER-ASSISTED; SILICON DIOXIDE; URINE;

EID: 84860483903     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2012.04683.x     Document Type: Article

References (35)

1. Simons M, Raposo G. Exosomes - vesicular carriers for intercellular communication. Curr Opin Cell Biol 2009; 21: 575-81.
2. Nieuwland R, Sturk A. Why do cells release vesicles? Thromb Res 2010; 125: S49-51.
3. Ratajczak J, Wysoczynski M, Hayek F, Janowska-Wieczorek A, Ratajczak MZ. Membrane-derived microvesicles: important and underappreciated mediators of cell-to-cell communication. Leukemia 2006; 20: 1487-95.
4. Berckmans RJ, Sturk A, Schaap MC, Nieuwland R. Cell-derived vesicles exposing coagulant tissue factor in saliva. Blood 2011; 117: 3172-80.
5. Manly DA, Wang JG, Glover SL, Kasthuri R, Liebman HA, Key NS, Mackman N. Increased microparticle tissue factor activity in cancer patients with venous thromboembolism. Thromb Res 2010; 125: 511-12.
6. Rautou PE, Leroyer AS, Ramkhelawon B, Devue C, Duflaut D, Vion AC, Nalbone G, Castier Y, Leseche G, Lehoux S, Tedgui A, Boulanger CM. Microparticles from human atherosclerotic plaques promote endothelial ICAM-1-dependent monocyte adhesion and transendothelial migration. Circ Res 2011; 108: 335-43.
7. van der Pol E, Hoekstra AG, Sturk A, Otto C, van Leeuwen TG, Nieuwland R. Optical and non-optical methods for detection and characterization of microparticles and exosomes. J Thromb Haemost 2010; 8: 2596-607.
8. Lacroix R, Robert S, Poncelet P, Kasthuri RS, Key NS, Dignat-George F. Standardization of platelet-derived microparticle enumeration by flow cytometry with calibrated beads: results of the International Society on Thrombosis and Haemostasis SSC Collaborative workshop. J Thromb Haemost 2010; 8: 2571-4.
9. Chandler WL, Yeung W, Tait JF. A new microparticle size calibration standard for use in measuring smaller microparticles using a new flow cytometer. J Thromb Haemost 2011; 9: 1216-24.
10. Mullier F, Bailly N, Chatelain C, Dogné JM, Chatelain B. More on: calibration for the measurement of microparticles: needs, interests, and limitations of calibrated polystyrene beads for flow cytometry-based quantification of biological microparticles. J Thromb Haemost 2011; 9: 1679-81.
11. Robert S, Poncelet P, Lacroix R, Raoult D, Dignat-George F. More on: calibration for the measurement of microparticles: value of calibrated polystyrene beads for flow cytometry-based sizing of biological microparticles. J Thromb Haemost 2011; 9: 1676-8.
12. Robert S, Poncelet P, Lacroix R, Arnaud L, Giraudo L, Hauchard A, Sampol J, Dignat-George F. Standardization of platelet-derived microparticle counting using calibrated beads and a Cytomics FC500 routine flow cytometer: a first step towards multicenter studies? J Thromb Haemost 2009; 7: 190-7.
13. Perez-Pujol S, Marker PH, Key NS. Platelet microparticles are heterogeneous and highly dependent on the activation mechanism: studies using a new digital flow cytometer. Cytometry A 2007; 71: 38-45.
14. Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A. Proteomics analysis of bladder cancer exosomes. Mol Cell Proteomics 2010; 9: 1324-38.
15. Yuana Y, Oosterkamp TH, Bahatyrova S, Ashcroft B, Garcia RP, Bertina RM, Osanto S. Atomic force microscopy: a novel approach to the detection of nanosized blood microparticles. J Thromb Haemost 2010; 8: 315-23.
16. Harrison P, Dragovic R, Albanyan A, Lawrie AS, Murphy M, Sargent I. Application of dynamic light scattering to the measurement of microparticles. J Thromb Haemost 2009; 7(Suppl. 2): OC-TU-056.
17. van Manen HJ, Verkuijlen P, Wittendorp P, Subramaniam V, van den Berg TK, Roos D, Otto C. Refractive index sensing of green fluorescent proteins in living cells using fluorescence lifetime imaging microscopy. Biophys J 2008; 94: L67-9.
18. Beuthan J, Minet O, Helfmann J, Herrig M, Muller G. The spatial variation of the refractive index in biological cells. Phys Med Biol 1996; 41: 369-82.
19. Foladori P, Quaranta A, Ziglio G. Use of silica microspheres having refractive index similar to bacteria for conversion of flow cytometric forward light scatter into biovolume. Water Res 2008; 42: 3757-66.
20. Briggs C, Harrison P, Samuel JM. Platelet counting. In: Michelson AD, ed. Platelets, 2nd edn. San Diego, CA: Academic Press, 2006: 475-83.
21. Collier JL. Flow cytometry and the single cell in phycology. J Phycol 2000; 36: 628-44.
22. Goddard G, Martin JC, Naivar M, Goodwin PM, Graves SW, Habbersett R, Nolan JP, Jett JH. Single particle high resolution spectral analysis flow cytometry. Cytometry A 2006; 69: 842-51.
23. Snow C. Flow cytometer electronics. Cytometry A 2004; 57: 63-9.
24. Bohren CF, Huffman DR. Absorption and Scattering of Light by Small Particles. New York, NY: Wiley, 1983.
25. Mätzler C. MATLAB functions for Mie scattering and absorption. 2002-11. Bern, Institute of Applied Physics: University of Bern, 2002.
26. Fattaccioli J, Baudry J, Emerard JD, Bertrand E, Goubault C, Henry N, Bibette J. Size and fluorescence measurements of individual droplets by flow cytometry. Soft Matter 2009; 5: 2232-8.
27. Laven P. MIEPLOT. Accessed 21 November 2011.
28. Shapiro HM, Leif RC. Practical Flow Cytometry, 4th edn. NJ: Wiley, 2003.
29. Yuana Y, Bertina RM, Osanto S. Pre-analytical and analytical issues in the analysis of blood microparticles. Thromb Haemost 2011; 105: 396-408.
30. Tocchetti EV, Flower RL, Lloyd JV. Assessment of in vitro-generated platelet microparticles using a modified flow cytometric strategy. Thromb Res 2001; 103: 47-55.
31. Lacroix R, Robert S, Poncelet P, Dignat-George F. Overcoming limitations of microparticle measurement by flow cytometry. Semin Thromb Hemost 2010; 36: 807-18.
32. Dragovic RA, Gardiner C, Brooks AS, Tannetta DS, Ferguson DJ, Hole P, Carr B, Redman CW, Harris AL, Dobson PJ, Harrison P, Sargent IL. Sizing and phenotyping of cellular vesicles using nanoparticle tracking analysis. Nanomedicine 2011; 7: 780-8.
33. White JG. Platelet structure. In: Michelson AD, ed. Platelets, 2nd edn. San Diego, CA: Academic Press, 2006: 45-73.
34. Diamant M, Nieuwland R, Pablo RF, Sturk A, Smit JW, Radder JK. Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus. Circulation 2002; 106: 2442-7.
35. Steen HB. Flow cytometer for measurement of the light scattering of viral and other submicroscopic particles. Cytometry A 2004; 57: 94-9.