Dietary pretreatment with green tea polyphenol, (-)-epigallocatechin-3-gallate reduces the bioavailability and hepatotoxicity of subsequent oral bolus doses of (-)-epigallocatechin-3-gallate

Food and Chemical Toxicology

Volumn 76, Issue , 2015, Pages 103-108

  James, Karma D ^a   Forester, Sarah C ^a,b   Lambert, Joshua D ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b CALIFORNIA STATE UNIVERSITY   (United States)

Author keywords

( ) Epigallocatechin 3 gallate; Bioavailability; Camellia sinensis; Green tea; Hepatotoxicity

Indexed keywords

ALANINE AMINOTRANSFERASE; EPIGALLOCATECHIN GALLATE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE PEROXIDASE 2; GLUTATHIONE PEROXIDASE 3; GLUTATHIONE PEROXIDASE 5; GLUTATHIONE PEROXIDASE 7; GLUTATHIONE REDUCTASE; HISTONE H2AX; MESSENGER RNA; UNCLASSIFIED DRUG; CATECHIN; POLYPHENOL; TEA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG BIOAVAILABILITY; DRUG MEGADOSE; GENE EXPRESSION; HISTONE PHOSPHORYLATION; HYPERTRANSAMINASEMIA; LIVER TOXICITY; MALE; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; ANALOGS AND DERIVATIVES; ANIMAL; BIOAVAILABILITY; BLOOD; CHEMISTRY; DIET; DRUG EFFECTS; LIVER; METABOLISM; ORAL DRUG ADMINISTRATION; TEA; VETERINARY;

CAMELLIA SINENSIS; CANIS FAMILIARIS; MUS;

ADMINISTRATION, ORAL; ALANINE TRANSAMINASE; ANIMALS; BIOLOGICAL AVAILABILITY; CATECHIN; DIET; GLUTATHIONE; LIVER; MALE; MICE; POLYPHENOLS; TEA;

EID: 84920732758     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2014.12.009     Document Type: Article

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