Genetic variants in antioxidant genes are associated with sperm DNA damage and risk of male infertility in a Chinese population

Free Radical Biology and Medicine

Volumn 52, Issue 4, 2012, Pages 775-780

  Ji, Guixiang ^a,b,c   Gu, Aihua ^a,b   Wang, Yubang ^a   Huang, Cong ^a,b   Hu, Fan ^a   Zhou, Yong ^d   Song, Ling ^a,b   Wang, Xinru ^a,b  

^a NANJING MEDICAL UNIVERSITY   (China)

^b Nanjing Medical University   (China)

^c NANJING INSTITUTE OF ENVIRONMENTAL SCIENCES   (China)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

8 Hydroxydeoxyguanosine; Antioxidant genes; DNA fragmentation; Free radicals; Male infertility; Oxidative stress; Polymorphisms

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ARYLDIALKYLPHOSPHATASE 1; CATALASE; EXTRACELLULAR SUPEROXIDE DISMUTASE; GLUTATHIONE PEROXIDASE 1; MANGANESE SUPEROXIDE DISMUTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

ADULT; ARTICLE; CHINESE; CONTROLLED STUDY; DNA DAMAGE; DNA FRAGMENTATION; GENE INTERACTION; GENE LOCUS; GENETIC VARIABILITY; GENOTYPE; HIGH RISK PATIENT; HUMAN; IMMUNOFLUORESCENCE; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; NICK END LABELING; POPULATION BASED CASE CONTROL STUDY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SPERM;

ADULT; ARYLDIALKYLPHOSPHATASE; CASE-CONTROL STUDIES; CATALASE; CHINA; DEOXYGUANOSINE; DNA FRAGMENTATION; EPISTASIS, GENETIC; GENETIC ASSOCIATION STUDIES; GENOTYPE; GLUTATHIONE PEROXIDASE; HUMANS; INFERTILITY, MALE; MALE; OXIDATIVE STRESS; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SEQUENCE ANALYSIS, DNA; SMOKING; SPERMATOZOA; SUPEROXIDE DISMUTASE;

EID: 84856227508     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.11.032     Document Type: Article

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