Functional genetic variation in the serotonin 5-HTTLPR modulates brain damage in frontotemporal dementia

Neurobiology of Aging

Volumn 36, Issue 1, 2015, Pages 446-451

  Premi, Enrico ^a   Archetti, Silvana ^b   Pilotto, Andrea ^a   Seripa, Davide ^c   Paghera, Barbara ^a   Padovani, Alessandro ^a   Borroni, Barbara ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

^b Brescia Hospital   (Italy)

^c Atherosclerosis and Thrombosis Unit Research Department   (Italy)

Author keywords

5 HTTLPR; Cognitive reserve; Frontotemporal dementia; Serotonin; SLC6A4; SPECT; Statistical parametric mapping

Indexed keywords

SEROTONIN; SEROTONIN TRANSPORTER; SLC6A4 PROTEIN, HUMAN;

ADULT; ARTICLE; BRAIN BLOOD FLOW; BRAIN DAMAGE; BRAIN PERFUSION; COGNITIVE RESERVE; CONTROLLED STUDY; FEMALE; FRONTAL LOBE; FRONTOTEMPORAL DEMENTIA; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; LEFT HEMISPHERE; MAJOR CLINICAL STUDY; MALE; MIDDLE FRONTAL GYRUS; MIDDLE TEMPORAL GYRUS; NEUROPSYCHOLOGICAL TEST; RIGHT HEMISPHERE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SUPERIOR FRONTAL GYRUS; TEMPORAL LOBE; AGED; BRAIN; BRAIN CIRCULATION; GENETICS; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; SEROTONINERGIC NERVE CELL; SYNAPTIC TRANSMISSION; VASCULARIZATION; VERY ELDERLY;

AGED; AGED, 80 AND OVER; BRAIN; CEREBROVASCULAR CIRCULATION; FEMALE; FRONTOTEMPORAL DEMENTIA; HUMANS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; POLYMORPHISM, GENETIC; SEROTONERGIC NEURONS; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SYNAPTIC TRANSMISSION; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 84920600561     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2014.07.008     Document Type: Article

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