Conformational dynamics of the focal adhesion targeting domain control specific functions of focal adhesion kinase in cells

Journal of Biological Chemistry

Volumn 290, Issue 1, 2015, Pages 478-491

  Kadaré, Gress ^a,b   Gervasi, Nicolas ^a,b   Brami Cherrier, Karen ^a,b,e   Blockus, Heike ^a,b,d   El Messari, Said ^a,b,f   Arold, Stefan T ^c,d   Girault, Jean Antoine ^a,b  

^a INSTITUT DU FER À MOULIN   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Saudi Arabia)

^d CNRS   (France)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITÉ DE FRANCHE COMTÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESION; ASSOCIATION REACTIONS; CELLS; CYTOLOGY; ENZYMES; MOLECULES; PHOSPHORYLATION;

CELLULAR FUNCTION; CONFORMATIONAL DYNAMICS; FOCAL ADHESION KINASE; FOCAL ADHESIONS; FUNCTIONAL INTERACTION; MEMBRANE RECEPTORS; MULTIPLE FUNCTION; SELF-ASSOCIATIONS;

CONFORMATIONS;

BOMBESIN; FOCAL ADHESION KINASE; MITOGEN ACTIVATED PROTEIN KINASE; HYBRID PROTEIN; PAXILLIN; PROTEIN BINDING;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL SHAPE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; FOCAL ADHESION; FOCAL ADHESION TARGETING DOMAIN; HINGE REGION; MOUSE; NONHUMAN; WILD TYPE; AMINO ACID SEQUENCE; ANIMAL; BACULOVIRIDAE; CHEMISTRY; CHLOROCEBUS AETHIOPS; COS CELL LINE; CYTOLOGY; ESCHERICHIA COLI; FIBROBLAST; GENE EXPRESSION; GENETICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; MOLECULAR GENETICS; MOLECULAR MODEL; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; SF9 CELL LINE; SPODOPTERA; ULTRASTRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; BACULOVIRIDAE; CERCOPITHECUS AETHIOPS; COS CELLS; ESCHERICHIA COLI; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; FOCAL ADHESION PROTEIN-TYROSINE KINASES; FOCAL ADHESIONS; GENE EXPRESSION; HUMANS; MICE; MICE, KNOCKOUT; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PAXILLIN; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; SF9 CELLS; SPODOPTERA;

EID: 84920532090     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.593632     Document Type: Article

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