Detection of a hidden folding intermediate in the focal adhesion target domain: Implications for its function and folding

Proteins: Structure, Function and Genetics

Volumn 65, Issue 2, 2006, Pages 259-265

  Zhou, Zheng ^a   Feng, Hanqiao ^a   Bai, Yawen ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

FAT domain; Functional intermediates; Hidden intermediate; Native state hydrogen exchange; Partially unfolded forms

Indexed keywords

FOCAL ADHESION KINASE; MUTANT PROTEIN;

AMINO TERMINAL SEQUENCE; ANALYTIC METHOD; ARTICLE; COMPUTER SIMULATION; FOCAL ADHESION; NATIVE STATE HYDROGEN EXCHANGE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION;

CIRCULAR DICHROISM; FOCAL ADHESION PROTEIN-TYROSINE KINASES; FOCAL ADHESIONS; HYDROGEN; KINETICS; MODELS, MOLECULAR; MUTATION; PROTEIN BINDING; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; TEMPERATURE; THERMODYNAMICS;

EID: 33749025025     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.21107     Document Type: Article

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