Altered sensory experience exacerbates stable dendritic spine and synapse loss in a mouse model of huntington’s disease

Journal of Neuroscience

Volumn 35, Issue 1, 2015, Pages 287-298

  Murmu, Reena Prity ^a   Li, Wen ^a   Szepesi, Zsuzsanna ^a   Li, Jia Yi ^a,b  

^a LUND UNIVERSITY   (Sweden)

^b NORTHEASTERN UNIVERSITY   (China)

Author keywords

Cognitive dysfunction; Dendritic spines; Huntington s disease; Sensory deprivation; Synaptic plasticity

Indexed keywords

ALPHA TUBULIN; BETA ACTIN; BOVINE SERUM ALBUMIN; GREEN FLUORESCENT PROTEIN; HUNTINGTIN; POSTSYNAPTIC DENSITY PROTEIN 95; SCAFFOLD PROTEIN; VESICULAR GLUTAMATE TRANSPORTER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; BRAIN SYNAPTOSOME; CELL FRACTIONATION; CELL LOSS; COGNITIVE DEFECT; CONTROLLED STUDY; DENDRITIC SPINE; FEMALE; FLUORESCENCE MICROSCOPY; GENETIC TRANSFORMATION; GENOTYPE; HUNTINGTON CHOREA; IMAGE PROCESSING; IMMUNOELECTRON MICROSCOPY; LEFT HEMISPHERE; MALE; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; POSTSYNAPTIC DENSITY; RIGHT HEMISPHERE; SENSORY DEPRIVATION (INTENTIONAL); SOMATOSENSORY CORTEX; SPINE STABILIZATION; SYNAPSE LOSS; SYNAPTIC POTENTIAL; SYNAPTIC TRANSMISSION; TIME LAPSE IMAGING; VIBRISSA; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CBA MOUSE; DISEASE MODEL; GENETICS; HUMAN; PATHOLOGY; PHYSIOLOGY; SENSORY DEPRIVATION; SYNAPSE; TRANSGENIC MOUSE;

ANIMALS; DENDRITIC SPINES; DISEASE MODELS, ANIMAL; HUMANS; HUNTINGTON DISEASE; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, TRANSGENIC; NEURONAL PLASTICITY; SENSORY DEPRIVATION; SYNAPSES; VIBRISSAE;

EID: 84920508062     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0244-14.2015     Document Type: Article

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