메뉴 건너뛰기




Volumn 140, Issue , 2014, Pages 616-623

Elationship between promoter methylation & tissue expression of MGMT gene in ovarian cancer

Author keywords

Epithelial ovarian tumour; MGMT; Ovarian cancer; Promoter methylation; Protein expression

Indexed keywords

METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; DNA LIGASE; DNA METHYLTRANSFERASE; MGMT PROTEIN, HUMAN; TUMOR PROTEIN; TUMOR SUPPRESSOR PROTEIN;

EID: 84920492001     PISSN: 09715916     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (10)

References (26)
  • 1
    • 0012959217 scopus 로고    scopus 로고
    • Aberrant DNA methylation in cancer: Potential clinical interventions
    • Strathdee G, Brown R. Aberrant DNA methylation in cancer: potential clinical interventions. Expert Rev Mol Med 2002; 4: 1-17.
    • (2002) Expert Rev Mol Med , vol.4 , pp. 1-17
    • Strathdee, G.1    Brown, R.2
  • 2
    • 0025116511 scopus 로고
    • DNA alkylation by the haloethylnitrosoureas: Nature of modifications produced and their enzymatic repair or removal
    • Ludlum DB. DNA alkylation by the haloethylnitrosoureas: nature of modifications produced and their enzymatic repair or removal. MutatRes 1990; 233: 117-26.
    • (1990) MutatRes , vol.233 , pp. 117-126
    • Ludlum, D.B.1
  • 3
    • 0034028030 scopus 로고    scopus 로고
    • Repair of O6-alkylguanine by alkyltransferases
    • Pegg AE. Repair of O6-alkylguanine by alkyltransferases. Mutat Res 2000; 462: 83-100.
    • (2000) Mutat Res , vol.462 , pp. 83-100
    • Pegg, A.E.1
  • 4
    • 34247638013 scopus 로고    scopus 로고
    • CpG island methylation, response to combination chemotherapy, and patient survival in advanced microsatellite stable colorectal carcinoma
    • Ogino S, Meyerhardt JA, Kawasaki T, Clark JW, Ryan DP. Kulke MH, et al. CpG island methylation, response to combination chemotherapy, and patient survival in advanced microsatellite stable colorectal carcinoma. Virchows Arch 2007; 450: 529-37.
    • (2007) Virchows Arch , vol.450 , pp. 529-537
    • Ogino, S.1    Meyerhardt, J.A.2    Kawasaki, T.3    Clark, J.W.4    Ryan, D.P.5    Kulke, M.H.6
  • 5
    • 33845607550 scopus 로고    scopus 로고
    • Loss of expression of DNA repair enzyme MGMT in oral leukoplakia and early oral squamous cell carcinoma. A prognostic tool?
    • Rodriguez MJ, Acha A, Ruesga MT, Rodriguez C, Rivera JM, Aguirre JM. Loss of expression of DNA repair enzyme MGMT in oral leukoplakia and early oral squamous cell carcinoma. A prognostic tool? Cancer Lett 2007, 245: 263-8.
    • (2007) Cancer Lett , vol.245 , pp. 263-268
    • Rodriguez, M.J.1    Acha, A.2    Ruesga, M.T.3    Rodriguez, C.4    Rivera, J.M.5    Aguirre, J.M.6
  • 6
    • 33846024654 scopus 로고    scopus 로고
    • Oesophageal squamous cell carcinoma may develop within a background of accumulating DNA methylation in normal and dysplastic mucosa
    • Ishii T, Murakami J, Notohara K, Cullings HM, Sasamoto H, Kambara T, et al. Oesophageal squamous cell carcinoma may develop within a background of accumulating DNA methylation in normal and dysplastic mucosa. Gut 2007; 56: 13-9.
    • (2007) Gut , vol.56 , pp. 13-19
    • Ishii, T.1    Murakami, J.2    Notohara, K.3    Cullings, H.M.4    Sasamoto, H.5    Kambara, T.6
  • 7
    • 32644467225 scopus 로고    scopus 로고
    • Methylated tumor- specific DNA as a plasma biomarker in patients with glioma
    • Weaver KD, Grossman SA, Herman JG. Methylated tumor- specific DNA as a plasma biomarker in patients with glioma. Cancer Invest 2006; 24: 35-40.
    • (2006) Cancer Invest , vol.24 , pp. 35-40
    • Weaver, K.D.1    Grossman, S.A.2    Herman, J.G.3
  • 8
    • 27744536637 scopus 로고    scopus 로고
    • Ovarian cancer, peritoneal carcinoma, and fallopian tube carcinoma
    • In: DeVita VT Jr., Hellman S, Rosenberg SA, editors, Section 32.4, 7th ed. Philadelphia: Lippincott, Williams and Wilkins
    • Ozols RF, Schwartz PE, Eifel PJ. Ovarian cancer, peritoneal carcinoma, and fallopian tube carcinoma. In: DeVita VT Jr., Hellman S, Rosenberg SA, editors. Cancer: principles and practice of oncology, Section 32.4, 7th ed. Philadelphia: Lippincott, Williams and Wilkins; 2005. p. 1364-98.
    • (2005) Cancer: Principles and practice of oncology , pp. 1364-1398
    • Ozols, R.F.1    Schwartz, P.E.2    Eifel, P.J.3
  • 10
    • 2642571071 scopus 로고    scopus 로고
    • Frequency of symptoms of ovarian cancer in women presenting to primary care clinics
    • Goff BA, Mandel LS, Melancon CH, Muntz HG. Frequency of symptoms of ovarian cancer in women presenting to primary care clinics. JAMA 2004; 291: 2705-12.
    • (2004) JAMA , vol.291 , pp. 2705-2712
    • Goff, B.A.1    Mandel, L.S.2    Melancon, C.H.3    Muntz, H.G.4
  • 11
    • 84891161285 scopus 로고    scopus 로고
    • FIGO Committee on Gynecologic Oncology. Staging classification for cancer of the ovary, fallopian tube and peritoneum
    • Prat J; FIGO Committee on Gynecologic Oncology. Staging classification for cancer of the ovary, fallopian tube and peritoneum. Int J Gynecol Obstet 2014; 124: 1-5.
    • (2014) Int J Gynecol Obstet , vol.124 , pp. 1-5
    • Prat, J.1
  • 12
    • 79251536531 scopus 로고    scopus 로고
    • Comprehensive analysis of MGMT promoter methylation: Correlation with MGMT expression and clinical response in GBM
    • Shah N, Lin B, Sibenaller Z, Ryken T, Lee H, Yoon J-G, et al. Comprehensive analysis of MGMT promoter methylation: Correlation with MGMT expression and clinical response in GBM. PLoS One 2011; 6: e16146.
    • (2011) PLoS One , vol.6
    • Shah, N.1    Lin, B.2    Sibenaller, Z.3    Ryken, T.4    Lee, H.5    Yoon, J.-G.6
  • 13
    • 1642334155 scopus 로고    scopus 로고
    • Promoter hypermethylation of MGMT, CDH1, RAR-f and SYK tumor suppressor genes in granulose cell tumors (GCTs) of ovarian origin
    • Dhillon VS, Young AR, Husain SA, Aslam M. Promoter hypermethylation of MGMT, CDH1, RAR-f and SYK tumor suppressor genes in granulose cell tumors (GCTs) of ovarian origin. Br J Cancer 2004; 90: 874-81.
    • (2004) Br J Cancer , vol.90 , pp. 874-881
    • Dhillon, V.S.1    Young, A.R.2    Husain, S.A.3    Aslam, M.4
  • 14
    • 33947536116 scopus 로고    scopus 로고
    • A simplified laboratory validated assay for MGMT promoter hypermethylation analysis of glioma specimens from formalin- fixed paraffin-embedded tissue
    • Cankovic M, Mikkelsen T, Rosenblum ML, Zarbo RJ. A simplified laboratory validated assay for MGMT promoter hypermethylation analysis of glioma specimens from formalin- fixed paraffin-embedded tissue. Lab Invest 2007; 87: 392-7.
    • (2007) Lab Invest , vol.87 , pp. 392-397
    • Cankovic, M.1    Mikkelsen, T.2    Rosenblum, M.L.3    Zarbo, R.J.4
  • 15
    • 0033557903 scopus 로고    scopus 로고
    • Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
    • Esteller M, Hamilton SR, Burger PC, Baylin SB, Herman JG. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res 1999; 59: 793-7.
    • (1999) Cancer Res , vol.59 , pp. 793-797
    • Esteller, M.1    Hamilton, S.R.2    Burger, P.C.3    Baylin, S.B.4    Herman, J.G.5
  • 16
    • 77954641662 scopus 로고    scopus 로고
    • Messenger RNA expression and methylation of candidate tumor-suppressor genes and risk of ovarian cancer- a case-control analysis
    • Jiaze A, Qingyi W, Zhensheng L, Karen H L, Xi C, Gordon BM, et al. Messenger RNA expression and methylation of candidate tumor-suppressor genes and risk of ovarian cancer- a case-control analysis. Int J Mol Epidemiol Genet 2010; 1: 1-10.
    • (2010) Int J Mol Epidemiol Genet , vol.1 , pp. 1-10
    • Jiaze, A.1    Qingyi, W.2    Zhensheng, L.3    Karen, H.L.4    Xi, C.5    Gordon, B.M.6
  • 17
    • 33745199586 scopus 로고    scopus 로고
    • The high frequency of de novo promoter methylation in synchronous primary endometrial and ovarian carcinomas
    • Furlan D, Carnevali I, Marcomini B, Cerutti R, Dainese E, Capella C, et al. The high frequency of de novo promoter methylation in synchronous primary endometrial and ovarian carcinomas. Clin Cancer Res 2006; 12: 3329-36.
    • (2006) Clin Cancer Res , vol.12 , pp. 3329-3336
    • Furlan, D.1    Carnevali, I.2    Marcomini, B.3    Cerutti, R.4    Dainese, E.5    Capella, C.6
  • 18
    • 33746707463 scopus 로고    scopus 로고
    • Methylation and expression analysis of 15 genes and three normally-methylated genes in 13 ovarian cancer cell lines
    • Imura M, Yamahita S, Cai LY, Furuta J, Wakabayashi M, Yasugi T, et al. Methylation and expression analysis of 15 genes and three normally-methylated genes in 13 ovarian cancer cell lines. Cancer Lett 2006; 241: 213-20.
    • (2006) Cancer Lett , vol.241 , pp. 213-220
    • Imura, M.1    Yamahita, S.2    Cai, L.Y.3    Furuta, J.4    Wakabayashi, M.5    Yasugi, T.6
  • 21
    • 22344447421 scopus 로고    scopus 로고
    • Prognostic significance of O6-methylguanine-DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression in anaplastic gliomas
    • Brell M, Tor tosa A, Verger E, Gil GM, Vinolas N, Villa S, et al. Prognostic significance of O6-methylguanine-DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression in anaplastic gliomas. Clin Cancer Res 2005; 11: 5167-74.
    • (2005) Clin Cancer Res , vol.11 , pp. 5167-5174
    • Brell, M.1    Tor Tosa, A.2    Verger, E.3    Gil, G.M.4    Vinolas, N.5    Villa, S.6
  • 22
    • 80052699883 scopus 로고    scopus 로고
    • Inactivation of O6-methyguanine-DNA methyltransferase (MGMT) by promoter hypermethylation: A key factor of epithelial ovarian carcinogenesis in specific histologic types
    • Roh HJ, Suh DS, Choi KU, Yoo HJ, Joo WD, Yoon MS. Inactivation of O6-methyguanine-DNA methyltransferase (MGMT) by promoter hypermethylation: A key factor of epithelial ovarian carcinogenesis in specific histologic types. J Obstet Gynaecol Res 2011; 37: 851-60.
    • (2011) J Obstet Gynaecol Res , vol.37 , pp. 851-860
    • Roh, H.J.1    Suh, D.S.2    Choi, K.U.3    Yoo, H.J.4    Joo, W.D.5    Yoon, M.S.6
  • 23
    • 0029933660 scopus 로고    scopus 로고
    • Methylation of CpG island transcription factor binding sites is unnecessary for aberrant silencing of the human MGMT gene
    • Pieper RO, Patel S, Ting SA, Futscher BW, Costello JF. Methylation of CpG island transcription factor binding sites is unnecessary for aberrant silencing of the human MGMT gene. J Biol Chem 1996; 271: 13916-24.
    • (1996) J Biol Chem , vol.271 , pp. 13916-13924
    • Pieper, R.O.1    Patel, S.2    Ting, S.A.3    Futscher, B.W.4    Costello, J.F.5
  • 24
    • 0037068351 scopus 로고    scopus 로고
    • Gene silencing in mammalian cells and the spread of DNA methylation
    • Turker MS. Gene silencing in mammalian cells and the spread of DNA methylation. Oncogene 2002; 21: 5388-93.
    • (2002) Oncogene , vol.21 , pp. 5388-5393
    • Turker, M.S.1
  • 25
    • 0037068393 scopus 로고    scopus 로고
    • DNA methylation and gene silencing in cancer: Which is the guilty party?
    • Clark SJ, Melki J. DNA methylation and gene silencing in cancer: which is the guilty party? Oncogene 2002; 21: 5380-7.
    • (2002) Oncogene , vol.21 , pp. 5380-5387
    • Clark, S.J.1    Melki, J.2
  • 26
    • 34548147443 scopus 로고    scopus 로고
    • Optimization of quantitative MGMT promoter methylation analysis using pyrosequencing and combined bisulfite restriction analysis
    • Thomas M, Christoph B, Osman El-Maarri, Anika H, Denise E, Johannes S, et al. Optimization of quantitative MGMT promoter methylation analysis using pyrosequencing and combined bisulfite restriction analysis. J Mol Diagn 2007; 9: 368-81.
    • (2007) J Mol Diagn , vol.9 , pp. 368-381
    • Thomas, M.1    Christoph, B.2    El-Maarri, O.3    Anika, H.4    Denise, E.5    Johannes, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.