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Volumn 241, Issue 2, 2006, Pages 213-220

Methylation and expression analysis of 15 genes and three normally-methylated genes in 13 Ovarian cancer cell lines

Author keywords

Demethylation; DNA methylation; Epigenetics; Gene expression; Ovarian cancers

Indexed keywords

BRCA1 PROTEIN; DNA; GLUTATHIONE TRANSFERASE P1; MELANOMA ANTIGEN 1; MELANOMA ANTIGEN 3; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROTEIN; PROTEIN CDKN2A; PROTEIN ESR1; PROTEIN FLNC; PROTEIN HAND1; PROTEIN HRASLS; PROTEIN LOX; PROTEIN MAGE B2; PROTEIN MLH1; PROTEIN TERC; PROTEIN THBD; TISSUE INHIBITOR OF METALLOPROTEINASE 3; UNCLASSIFIED DRUG; UVOMORULIN;

EID: 33746707463     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2005.10.010     Document Type: Article
Times cited : (39)

References (39)
  • 1
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones P.A., and Baylin S.B. The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 3 (2002) 415-428
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 2
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman J.G., and Baylin S.B. Gene silencing in cancer in association with promoter hypermethylation. N. Engl. J. Med. 349 (2003) 2042-2054
    • (2003) N. Engl. J. Med. , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 3
    • 10744233452 scopus 로고    scopus 로고
    • Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2′-deoxycytidine (decitabine) in hematopoietic malignancies
    • Issa J.P., Garcia-Manero G., Giles F.J., Mannari R., Thomas D., Faderl S., et al. Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2′-deoxycytidine (decitabine) in hematopoietic malignancies. Blood 103 (2004) 1635-1640
    • (2004) Blood , vol.103 , pp. 1635-1640
    • Issa, J.P.1    Garcia-Manero, G.2    Giles, F.J.3    Mannari, R.4    Thomas, D.5    Faderl, S.6
  • 4
  • 5
    • 1142275253 scopus 로고    scopus 로고
    • Frequent hypomethylation in multiple promoter CpG islands is associated with global hypomethylation, but not with frequent promoter hypermethylation
    • Kaneda A., Tsukamoto T., Takamura-Enya T., Watanabe N., Kaminishi M., Sugimura T., et al. Frequent hypomethylation in multiple promoter CpG islands is associated with global hypomethylation, but not with frequent promoter hypermethylation. Cancer Sci. 95 (2004) 58-64
    • (2004) Cancer Sci. , vol.95 , pp. 58-64
    • Kaneda, A.1    Tsukamoto, T.2    Takamura-Enya, T.3    Watanabe, N.4    Kaminishi, M.5    Sugimura, T.6
  • 8
    • 0033580432 scopus 로고    scopus 로고
    • Methylation of the BRCA1 promoter region in sporadic breast and ovarian cancer: correlation with disease characteristics
    • Catteau A., Harris W.H., Xu C.F., and Solomon E. Methylation of the BRCA1 promoter region in sporadic breast and ovarian cancer: correlation with disease characteristics. Oncogene 18 (1999) 1957-1965
    • (1999) Oncogene , vol.18 , pp. 1957-1965
    • Catteau, A.1    Harris, W.H.2    Xu, C.F.3    Solomon, E.4
  • 10
    • 0034307160 scopus 로고    scopus 로고
    • BRCA1 promoter region hypermethylation in ovarian carcinoma: a population-based study
    • Baldwin R.L., Nemeth E., Tran H., Shvartsman H., Cass I., Narod S., et al. BRCA1 promoter region hypermethylation in ovarian carcinoma: a population-based study. Cancer Res. 60 (2000) 5329-5333
    • (2000) Cancer Res. , vol.60 , pp. 5329-5333
    • Baldwin, R.L.1    Nemeth, E.2    Tran, H.3    Shvartsman, H.4    Cass, I.5    Narod, S.6
  • 11
    • 0037099625 scopus 로고    scopus 로고
    • Epigenetic factors controlling the BRCA1 and BRCA2 genes in sporadic ovarian cancer
    • Chan K.Y., Ozcelik H., Cheung A.N., Ngan H.Y., and Khoo U.S. Epigenetic factors controlling the BRCA1 and BRCA2 genes in sporadic ovarian cancer. Cancer Res. 62 (2002) 4151-4156
    • (2002) Cancer Res. , vol.62 , pp. 4151-4156
    • Chan, K.Y.1    Ozcelik, H.2    Cheung, A.N.3    Ngan, H.Y.4    Khoo, U.S.5
  • 14
    • 0037148422 scopus 로고    scopus 로고
    • Methylation status of oestrogen receptor-alpha gene promoter sequences in human ovarian epithelial cell lines
    • O'Doherty A.M., Church S.W., Russell S.E., Nelson J., and Hickey I. Methylation status of oestrogen receptor-alpha gene promoter sequences in human ovarian epithelial cell lines. Br. J. Cancer 86 (2002) 282-284
    • (2002) Br. J. Cancer , vol.86 , pp. 282-284
    • O'Doherty, A.M.1    Church, S.W.2    Russell, S.E.3    Nelson, J.4    Hickey, I.5
  • 15
    • 0141962933 scopus 로고    scopus 로고
    • Mismatch repair gene expression defects contribute to microsatellite instability in ovarian carcinoma
    • Geisler J.P., Goodheart M.J., Sood A.K., Holmes R.J., Hatterman-Zogg M.A., and Buller R.E. Mismatch repair gene expression defects contribute to microsatellite instability in ovarian carcinoma. Cancer 98 (2003) 2199-2206
    • (2003) Cancer , vol.98 , pp. 2199-2206
    • Geisler, J.P.1    Goodheart, M.J.2    Sood, A.K.3    Holmes, R.J.4    Hatterman-Zogg, M.A.5    Buller, R.E.6
  • 16
    • 0030895616 scopus 로고    scopus 로고
    • Rare mutations and no hypermethylation at the CDKN2A locus in epithelial ovarian tumours
    • Shih Y.C., Kerr J., Liu J., Hurst T., Khoo S.K., Ward B., et al. Rare mutations and no hypermethylation at the CDKN2A locus in epithelial ovarian tumours. Int. J. Cancer 70 (1997) 508-511
    • (1997) Int. J. Cancer , vol.70 , pp. 508-511
    • Shih, Y.C.1    Kerr, J.2    Liu, J.3    Hurst, T.4    Khoo, S.K.5    Ward, B.6
  • 17
    • 0031888206 scopus 로고    scopus 로고
    • No evidence exists for methylation inactivation of the p16 tumor suppressor gene in ovarian carcinogenesis
    • Ryan A., Al-Jehani R.M., Mulligan K.T., and Jacobs I.J. No evidence exists for methylation inactivation of the p16 tumor suppressor gene in ovarian carcinogenesis. Gynecol. Oncol. 68 (1998) 14-17
    • (1998) Gynecol. Oncol. , vol.68 , pp. 14-17
    • Ryan, A.1    Al-Jehani, R.M.2    Mulligan, K.T.3    Jacobs, I.J.4
  • 20
    • 0035888160 scopus 로고    scopus 로고
    • Hypermethylation of the CpG island of the RASSF1A gene in ovarian and renal cell carcinomas
    • Yoon J.H., Dammann R., and Pfeifer G.P. Hypermethylation of the CpG island of the RASSF1A gene in ovarian and renal cell carcinomas. Int. J. Cancer 94 (2001) 212-217
    • (2001) Int. J. Cancer , vol.94 , pp. 212-217
    • Yoon, J.H.1    Dammann, R.2    Pfeifer, G.P.3
  • 21
    • 0035932393 scopus 로고    scopus 로고
    • Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours
    • Agathanggelou A., Honorio S., Macartney D.P., Martinez A., Dallol A., Rader J., et al. Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours. Oncogene 20 (2001) 1509-1518
    • (2001) Oncogene , vol.20 , pp. 1509-1518
    • Agathanggelou, A.1    Honorio, S.2    Macartney, D.P.3    Martinez, A.4    Dallol, A.5    Rader, J.6
  • 22
    • 0035099160 scopus 로고    scopus 로고
    • Primary ovarian carcinomas display multiple methylator phenotypes involving known tumor suppressor genes
    • Strathdee G., Appleton K., Illand M., Millan D.W., Sargent J., Paul J., et al. Primary ovarian carcinomas display multiple methylator phenotypes involving known tumor suppressor genes. Am. J. Pathol. 158 (2001) 1121-1127
    • (2001) Am. J. Pathol. , vol.158 , pp. 1121-1127
    • Strathdee, G.1    Appleton, K.2    Illand, M.3    Millan, D.W.4    Sargent, J.5    Paul, J.6
  • 23
    • 0036847546 scopus 로고    scopus 로고
    • Methylation profiles of sporadic ovarian tumors and nonmalignant ovaries from high-risk women
    • Rathi A., Virmani A.K., Schorge J.O., Elias K.J., Maruyama R., Minna J.D., et al. Methylation profiles of sporadic ovarian tumors and nonmalignant ovaries from high-risk women. Clin. Cancer Res. 8 (2002) 3324-3331
    • (2002) Clin. Cancer Res. , vol.8 , pp. 3324-3331
    • Rathi, A.1    Virmani, A.K.2    Schorge, J.O.3    Elias, K.J.4    Maruyama, R.5    Minna, J.D.6
  • 26
    • 0032532092 scopus 로고    scopus 로고
    • Inactivation of glutathione S-transferase P1 gene by promoter hypermethylation in human neoplasia
    • Esteller M., Corn P.G., Urena J.M., Gabrielson E., Baylin S.B., and Herman J.G. Inactivation of glutathione S-transferase P1 gene by promoter hypermethylation in human neoplasia. Cancer Res. 58 (1998) 4515-4518
    • (1998) Cancer Res. , vol.58 , pp. 4515-4518
    • Esteller, M.1    Corn, P.G.2    Urena, J.M.3    Gabrielson, E.4    Baylin, S.B.5    Herman, J.G.6
  • 27
    • 0033557903 scopus 로고    scopus 로고
    • Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
    • Esteller M., Hamilton S.R., Burger P.C., Baylin S.B., and Herman J.G. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res. 59 (1999) 793-797
    • (1999) Cancer Res. , vol.59 , pp. 793-797
    • Esteller, M.1    Hamilton, S.R.2    Burger, P.C.3    Baylin, S.B.4    Herman, J.G.5
  • 28
    • 0035135973 scopus 로고    scopus 로고
    • Lack of telomerase RNA gene hTERC expression in alternative lengthening of telomeres cells is associated with methylation of the hTERC promoter
    • Hoare S.F., Bryce L.A., Wisman G.B., Burns S., Going J.J., van der Zee A.G., et al. Lack of telomerase RNA gene hTERC expression in alternative lengthening of telomeres cells is associated with methylation of the hTERC promoter. Cancer Res. 61 (2001) 27-32
    • (2001) Cancer Res. , vol.61 , pp. 27-32
    • Hoare, S.F.1    Bryce, L.A.2    Wisman, G.B.3    Burns, S.4    Going, J.J.5    van der Zee, A.G.6
  • 29
    • 0033558192 scopus 로고    scopus 로고
    • Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers
    • Bachman K.E., Herman J.G., Corn P.G., Merlo A., Costello J.F., Cavenee W.K., et al. Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers. Cancer Res. 59 (1999) 798-802
    • (1999) Cancer Res. , vol.59 , pp. 798-802
    • Bachman, K.E.1    Herman, J.G.2    Corn, P.G.3    Merlo, A.4    Costello, J.F.5    Cavenee, W.K.6
  • 31
    • 0029050422 scopus 로고
    • Characterization of human ovarian surface epithelial cells immortalized by human papilloma viral oncogenes (HPV-E6E7 ORFs)
    • Tsao S.W., Mok S.C., Fey E.G., Fletcher J.A., Wan T.S., Chew E.C., et al. Characterization of human ovarian surface epithelial cells immortalized by human papilloma viral oncogenes (HPV-E6E7 ORFs). Exp. Cell Res. 218 (1995) 499-507
    • (1995) Exp. Cell Res. , vol.218 , pp. 499-507
    • Tsao, S.W.1    Mok, S.C.2    Fey, E.G.3    Fletcher, J.A.4    Wan, T.S.5    Chew, E.C.6
  • 32
    • 0035886616 scopus 로고    scopus 로고
    • Nonrandom chromosomal imbalances in human ovarian surface epithelial cells immortalized by HPV16-E6E7 viral oncogenes
    • Tsao S.W., Wong N., Wang X., Liu Y., Wan T.S., Fung L.F., et al. Nonrandom chromosomal imbalances in human ovarian surface epithelial cells immortalized by HPV16-E6E7 viral oncogenes. Cancer Genet. Cytogenet. 130 (2001) 141-149
    • (2001) Cancer Genet. Cytogenet. , vol.130 , pp. 141-149
    • Tsao, S.W.1    Wong, N.2    Wang, X.3    Liu, Y.4    Wan, T.S.5    Fung, L.F.6
  • 33
    • 3242885344 scopus 로고    scopus 로고
    • Decreased expression of the seven ARP2/3 complex genes in human gastric cancers
    • Kaneda A., Kaminishi M., Sugimura T., and Ushijima T. Decreased expression of the seven ARP2/3 complex genes in human gastric cancers. Cancer Lett. 212 (2004) 203-210
    • (2004) Cancer Lett. , vol.212 , pp. 203-210
    • Kaneda, A.1    Kaminishi, M.2    Sugimura, T.3    Ushijima, T.4
  • 35
    • 14644396228 scopus 로고    scopus 로고
    • Detection and interpretation of altered methylation patterns in cancer cells
    • Ushijima T. Detection and interpretation of altered methylation patterns in cancer cells. Nat. Rev. Cancer 5 (2005) 223-231
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 223-231
    • Ushijima, T.1
  • 36
    • 0034729168 scopus 로고    scopus 로고
    • Lack of mutation at p16INK4A gene but expression of aberrant p16INK4A RNA transcripts in human ovarian carcinoma
    • Suh S.I., Cho J.W., Baek W.K., Suh M.H., and Carson D.A. Lack of mutation at p16INK4A gene but expression of aberrant p16INK4A RNA transcripts in human ovarian carcinoma. Cancer Lett. 153 (2000) 175-182
    • (2000) Cancer Lett. , vol.153 , pp. 175-182
    • Suh, S.I.1    Cho, J.W.2    Baek, W.K.3    Suh, M.H.4    Carson, D.A.5
  • 37
    • 0032549041 scopus 로고    scopus 로고
    • p16/MTS1 inactivation in ovarian carcinomas: high frequency of reduced protein expression associated with hyper-methylation or mutation in endometrioid and mucinous tumors
    • Milde-Langosch K., Ocon E., Becker G., and Loning T. p16/MTS1 inactivation in ovarian carcinomas: high frequency of reduced protein expression associated with hyper-methylation or mutation in endometrioid and mucinous tumors. Int. J. Cancer 79 (1998) 61-65
    • (1998) Int. J. Cancer , vol.79 , pp. 61-65
    • Milde-Langosch, K.1    Ocon, E.2    Becker, G.3    Loning, T.4
  • 38
    • 0036513696 scopus 로고    scopus 로고
    • Promoter hypermethylation and post-transcriptional mechanisms for reduced BRCA1 immunoreactivity in sporadic human breast cancers
    • Miyamoto K., Fukutomi T., Asada K., Wakazono K., Tsuda H., Asahara T., et al. Promoter hypermethylation and post-transcriptional mechanisms for reduced BRCA1 immunoreactivity in sporadic human breast cancers. Jpn. J. Clin. Oncol. 32 (2002) 79-84
    • (2002) Jpn. J. Clin. Oncol. , vol.32 , pp. 79-84
    • Miyamoto, K.1    Fukutomi, T.2    Asada, K.3    Wakazono, K.4    Tsuda, H.5    Asahara, T.6


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