Analytical aspects of achiral and cyclodextrin-mediated capillary electrophoresis of warfarin and its two main derivatives assisted by theoretical modeling

Journal of Chromatography A

Volumn 1377, Issue , 2015, Pages 106-113

  Nowak, Paweł ^a   Garnysz, Magdalena ^a   Mitoraj, Mariusz Paweł ^a   Sagan, Filip ^a   Woźniakiewicz, Michał ^a   Kościelniak, Paweł ^a  

^a JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

Acid dissociation constant; Capillary electrophoresis; Chiral separation; Cyclodextrins; PKa shift; Warfarin

Indexed keywords

CAPILLARY ELECTROPHORESIS; CHIRALITY; CYCLODEXTRINS; DISSOCIATION; ELECTROPHORETIC MOBILITY; SEPARATION;

ACID DISSOCIATION CONSTANTS; CHIRAL SEPARATIONS; DIASTEREOMERIC COMPLEXES; MOBILITY SHIFT ASSAYS; OPTIMUM CONDITIONS; PKA SHIFT; THEORETICAL MODELING; WARFARIN;

DENSITY FUNCTIONAL THEORY;

10 HYDROXYWARFARIN; 7 HYDROXYWARFARIN; CYCLODEXTRIN; UNCLASSIFIED DRUG; WARFARIN; 10-HYDROXYWARFARIN; 7-HYDROXYWARFARIN;

ACID DISSOCIATION CONSTANT; ARTICLE; CAPILLARY ELECTROPHORESIS; CHEMICAL STRUCTURE; CHIRALITY; COMPLEX FORMATION; CONTROLLED STUDY; DENSITY FUNCTIONAL THEORY; ENANTIOMER; ENANTIOSELECTIVITY; GEL MOBILITY SHIFT ASSAY; IONIZATION; MIGRATION; PH; PHASE PARTITIONING; PROTON TRANSPORT; SEPARATION TECHNIQUE; THEORETICAL MODEL; ANALOGS AND DERIVATIVES; CHEMISTRY; ELECTROPHORESIS; STEREOISOMERISM;

CYCLODEXTRINS; ELECTROPHORESIS; ELECTROPHORESIS, CAPILLARY; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HYDROGEN-ION CONCENTRATION; MODELS, THEORETICAL; STEREOISOMERISM; WARFARIN;

EID: 84920402269     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2014.12.030     Document Type: Article

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