Determination of trace enantiomeric impurities in chiral compounds by capillary electrophoresis with uncoated, cationic, anionic and neutral surface modified capillaries

Journal of Chromatography A

Volumn 817, Issue 1-2, 1998, Pages 83-90

  Assi, K H ^a   Abushoffa, A M ^a   Altria, K D ^b   Clark, B J ^a  

^a UNIVERSITY OF BRADFORD   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Coated capillaries; Enantiomer separation; Pharmaceutical analysis; Propranolol; Tryptophan; Warfarin

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; 2,6 O DIMETHYL BETA CYCLODEXTRIN; PROPRANOLOL; TRYPTOPHAN; WARFARIN;

ARTICLE; CAPILLARY ELECTROPHORESIS; CHIRALITY; DRUG DETERMINATION; DRUG IMPURITY; ENANTIOMER; PRIORITY JOURNAL;

EID: 0032555749     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9673(98)00245-3     Document Type: Article

References (16)

1. Sanger van degriend C.E., Wahlstrom H., Groningsson K., Widahlnasman M. J. Pharm. Biomed. Anal. 15:1997;1051-1061.
2. Rogan M.R., Altria K.D., Goodall D.M. Chirality. 6:1994;25.
3. Abushoffa A.M., Clark B.J. J. Chromatogr. A. 700:1995;51.
4. Nishi H., Terabe S. J. Chromatogr. 694:1995;245-276.
5. Mayer S., Schurig V. J. Liq. Chromatogr. 16:1993;915.
6. Francotte E., Jung M. Chromatographia. 42:1996;521.
7. Fanali S. J. Chromatogr. 474:1989;441.
8. Snopek J., Soini H., Novotny M., Smolkova-Keulemansova E., Jelinek I. J. Chromatogr. 559:1991;215.
9. Rawjee Y.Y., Vigh G. Anal. Chem. 66:1994;619.
10. Assi K.A., Altria K.D., Clark B.J. J. Pharm. Biomed. Anal. 15:1997;1041-1049.
11. Belder D., Schomburg G. J. Chromatogr. A. 666:1994;351.
12. Bjornsdottir I., Hansen S.H. Chirality. 7:1995;219.
13. Huang X., Luckey J., Gordon M.J., Zare R.N. Anal. Chem. 61:1989;766.
14. W.R. Jones, P. Jandik, US Pat., 5104506, 1992.
15. Yao X.W., Wu D., Regnier F.E. J. Chromatogr. 636:1993;21.
16. Wren S.A.C. J. Chromatogr. 636:1993;57.