Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration

Journal of Clinical Investigation

Volumn 125, Issue 1, 2015, Pages 105-116

  Byrne, Leah C ^a   Dalkara, Deniz ^b,c,d   Luna, Gabriel ^e   Fisher, Steven K ^e   Clérin, Emmanuelle ^b,c,d   Sahel, Jose Alain ^b,c,d   Léveillard, Thierry ^b,c,d   Flannery, John G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b INSERM   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d CNRS   (France)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ISOPROTEIN; MESSENGER RNA; RHODOPSIN; ROD DERIVED CONE VIABILITY FACTOR; ROD DERIVED CONE VIABILITY FACTOR L; THIOREDOXIN; UNCLASSIFIED DRUG; EYE PROTEIN; RDCVF PROTEIN, MOUSE;

ADENO ASSOCIATED VIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BLOOD RETINA BARRIER; CELL COUNT; CELL DEATH; CELL DENSITY; CELL LOSS; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFICACY; ELECTRORETINOGRAM; EYE FUNDUS; GENE EXPRESSION; GENE TARGETING; GENE TRANSFER; LIPID PEROXIDATION; MOUSE; NERVE CELL; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PHOTOPIC VISION; PHOTORECEPTOR OUTER SEGMENT; PROTEIN EXPRESSION; RETINA CONE; RETINA DEGENERATION; RETINA DYSTROPHY; RETINA ROD; TRANSGENE; VIRAL GENE THERAPY; VIRAL TROPISM; VIRUS GENOME; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; DEPENDOPARVOVIRUS; EVOKED VISUAL RESPONSE; GENE THERAPY; GENETIC TRANSDUCTION; GENETICS; METABOLISM; PATHOLOGY; PHOTOSTIMULATION; RETINAL DEGENERATION;

ANIMALS; CELL SURVIVAL; DEPENDOVIRUS; EVOKED POTENTIALS, VISUAL; EYE PROTEINS; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; MICE, INBRED C57BL; PHOTIC STIMULATION; RETINAL CONE PHOTORECEPTOR CELLS; RETINAL DEGENERATION; RETINAL ROD PHOTORECEPTOR CELLS; RHODOPSIN; THIOREDOXINS; TRANSDUCTION, GENETIC;

EID: 84920390777     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI65654     Document Type: Article

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