Enhanced gene delivery to the neonatal retina through systemic administration of tyrosine-mutated AAV9

Gene Therapy

Volumn 19, Issue 2, 2012, Pages 176-181

  Dalkara, D ^a,b   Byrne, L C ^c   Lee, T ^c   Hoffmann, N V ^c   Schaffer, D V ^a,b   Flannery, J G ^c  

^a University of California   (United States)

^b University of California at Berkeley   (United States)

^c University of California Berkeley   (United States)

Author keywords

Adeno associated virus; animal models of neurodegenerative disease; retina; systemic

Indexed keywords

PARVOVIRUS VECTOR; PHENYLALANINE; RHODOPSIN; TYROSINE;

ADENO ASSOCIATED VIRUS; ADENO ASSOCIATED VIRUS 9; ANIMAL EXPERIMENT; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; GENE EXPRESSION; GENETIC TRANSDUCTION; MOUSE; MUTATION; NEWBORN; NONHUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; PROMOTER REGION; RETINA; RETINA AMACRINE CELL; RETINA DEGENERATION; RETINA GANGLION CELL; RETINA ROD; VIRAL GENE DELIVERY SYSTEM; VIRUS CAPSID; VIRUS INFECTIVITY; VIRUS MUTANT; VIRUS PARTICLE;

ANIMALS; CENTRAL NERVOUS SYSTEM; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE THERAPY; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; MICE; MICE, INBRED C57BL; MUTATION; PROMOTER REGIONS, GENETIC; RETINA; RETINAL DEGENERATION; RETINAL ROD PHOTORECEPTOR CELLS; RHODOPSIN;

ADENO-ASSOCIATED VIRUS; ANIMALIA; MIRIDAE;

EID: 84856975718     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2011.163     Document Type: Article

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