Prevention of glucocorticoid induced-apoptosis of osteoblasts and osteocytes by protecting against endoplasmic reticulum (ER) stress in vitro and in vivo in female mice

Bone

Volumn 73, Issue , 2015, Pages 60-68

  Sato, Amy Y ^a   Tu, Xiaolin ^a   McAndrews, Kevin A ^a,b   Plotkin, Lilian I ^a,b   Bellido, Teresita ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b RICHARD L ROUDEBUSH VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Endoplasmic reticulum stress; Glucocorticoid induced osteoporosis; Osteoblasts; Osteocytes

Indexed keywords

ALENDRONIC ACID; BREFELDIN A; DEXAMETHASONE; GLUCOCORTICOID; GUANABENZ; INITIATION FACTOR 2ALPHA; PREDNISOLONE; REACTIVE OXYGEN METABOLITE; SALUBRINAL; TUNICAMYCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE DENSITY; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; CORTICAL BONE; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MINERALIZATION; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCYTE; PROTEIN DEPHOSPHORYLATION; PROTEIN FUNCTION; SKELETON; TRABECULAR BONE; ANIMAL; COMPARATIVE STUDY; CYTOLOGY; DRUG EFFECTS; ENDOPLASMIC RETICULUM; PHOSPHORYLATION;

ANIMALS; APOPTOSIS; ENDOPLASMIC RETICULUM; FEMALE; GLUCOCORTICOIDS; IN VITRO TECHNIQUES; MICE; OSTEOBLASTS; OSTEOCYTES; PHOSPHORYLATION;

EID: 84920274380     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2014.12.012     Document Type: Article

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