Metabolome and proteome profiling of complex i deficiency induced by rotenone

Journal of Proteome Research

Volumn 14, Issue 1, 2015, Pages 224-235

  Gielisch, Ina ^a,b   Meierhofer, David ^a  

^a MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Complex I deficiency (CI); iron sulfur cluster; mass spectrometry; metabolome profiling; multiple reaction monitoring (MRM); network analysis; pathway analysis; proteome profiling; rotenone

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; AMINO ACID MIXTURE; ANAPHASE PROMOTING COMPLEX; AURORA B KINASE; BILIRUBIN; COPROPORPHYRINOGEN OXIDASE; CYCLIN DEPENDENT KINASE 2; CYTOCHROME C; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE 2 ALPHA; FLAVINE ADENINE NUCLEOTIDE; FLAVINE MONONUCLEOTIDE; GALACTOSE; GLUTATHIONE; GLUTATHIONE DISULFIDE; IMPORTIN SUBUNIT ALPHA 1; KARYOPHERIN; KINESIN LIKE PROTEIN KIF11; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; POLO LIKE KINASE 1; PROTEIN; PROTEOME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; ROTENONE; UBIDECARENONE; UBIQUITIN CONJUGATING ENZYME; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANAPHASE; ANION EXCHANGE CHROMATOGRAPHY; APOPTOSIS; ARTICLE; BIOINFORMATICS; CARBOHYDRATE METABOLISM; CELL ADHESION; CELL CYCLE; CELL VIABILITY; CHROMOSOME SEGREGATION; CITRIC ACID CYCLE; COMPLEX I DEFICIENCY; CONTROLLED STUDY; CYTOKINESIS; CYTOSKELETON; DEPOLYMERIZATION; DNA SYNTHESIS; DOWN REGULATION; ELECTRON TRANSPORT; ENZYME ACTIVITY; GLUCONEOGENESIS; GLUTATHIONE METABOLISM; GLYCOLYSIS; HELA CELL LINE; HUMAN; HUMAN CELL; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY; M PHASE CELL CYCLE CHECKPOINT; MASS SPECTROMETRY; METABOLOME; METABOLOMICS; METAPHASE; MITOSIS SPINDLE; MOLECULAR WEIGHT; OLIGOMERIZATION; OXIDATIVE PHOSPHORYLATION; PENTOSE PHOSPHATE CYCLE; PORPHYRIN METABOLISM; PROTEOMICS; QUANTITATIVE ANALYSIS; RESPIRATORY CHAIN; RIBOSOME; SYNTHESIS; UPREGULATION; ANTAGONISTS AND INHIBITORS; CELL SURVIVAL; DEFICIENCY; METABOLISM;

APOPTOSIS; CELL SURVIVAL; ELECTRON TRANSPORT COMPLEX I; HELA CELLS; HUMANS; METABOLOME; PROTEOME; ROTENONE; UP-REGULATION;

EID: 84920266687     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr500894v     Document Type: Article

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