Campylobacter virulence and survival factors

Food Microbiology

Volumn 48, Issue , 2015, Pages 99-108

  Bolton, Declan J ^a  

^a TEAGASC FOOD RESEARCH CENTRE   (Ireland)

Author keywords

Campylobacter; Foodborne pathogens; Survival; Virulence factors

Indexed keywords

BACTERIA (MICROORGANISMS); CAMPYLOBACTER;

BACTERIAL PROTEIN; VIRULENCE FACTOR;

ANIMAL; CAMPYLOBACTER; CAMPYLOBACTERIOSIS; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; METABOLISM; MICROBIOLOGY; PATHOGENICITY; VIRULENCE;

ANIMALS; BACTERIAL PROTEINS; CAMPYLOBACTER; CAMPYLOBACTER INFECTIONS; HUMANS; VIRULENCE; VIRULENCE FACTORS;

EID: 84920262222     PISSN: 07400020     EISSN: 10959998     Source Type: Journal    
DOI: 10.1016/j.fm.2014.11.017     Document Type: Review

References (150)

1. Alemka A., Nothaft H., Zheng J., Szymanski C.M. N-glycosylation of Campylobacter jejuni surface proteins promotes bacterial fitness. Infect. Immun 2013, 81(5):1674-1682.
2. Alfredson D.A., Korolik V. Antibiotic resistance and resistance mechanisms in Campylobacter jejuni and Campylobacter coli. FEMS Microbiol. Lett. 2007, 277:123-132.
3. Asakura M., Yamasaki M., Yamamoto S., Igimi S. Deletion of peb4 gene impairs cell adhesion and biofilm formation in Campylobacter jejuni. FEMS Microbiol. Lett. 2007, 275:278-285.
4. Asakura M., Samosornsuk W., Hinenoya A., Misawa N., Nishimura K., Matsuhisa A., Yamasaki S. Development of a cytolethal distending toxin (cdt) gene-based species-specific multiplex PCR assay for the detection and identification of Campylobacter jejuni, Campylobacter coli and Campylobacter fetus. FEMS Immunol. Med. Microbiol. 2008, 52:260-266.
5. Ashgar S.S., Oldfield N.J., Wooldridge K.G., Jones M.A., Irving G.J., Turner D.P., Ala'Aldeen D.A. CapA, an autotransporter protein of Campylobacter jejuni mediates association with human epithelial cells and colonization of the chicken gut. J.Bacteriol. 2007, 189:1856-1865.
6. Atack J.M., Harvey P., Jones M.A., Kelly D.J. The Campylobacter jejuni thiol peroxidases Tpx and Bcp both contribute to aerotolerance and peroxide-mediated stress resistance but have distinct substrate specificities. J.Bacteriol. 2008, 190:5279-5290.
7. Atack J.M., Kelly D.J. Oxidative stress in Campylobacter jejuni: responses, resistance and regulation. Future Microbiol. 2009, 4:677-690.
8. Baek K.T., Vegge C.S., Brondsted L. HtrA chaperone activity contributes to host cell binding in Campylobacter jejuni. Gut Pathog. 2011, 3:13. 10.1186/1757-4749-3-13.
9. Bachtiar B.M., Coloe P.J., Fry B.N. Knockout mutagenesis of the kpsE gene of Campylobacter jejuni 81116 and its involvement in bacterium host interactions. FEMS Immunol. Med. Microbiol. 2007, 49:149-154.
10. Bacon D.J., Alm R.A., Burr D.H., Hu L., Kopecko D.J., Ewing C.P., Trust T.J., Guerry P. Involvement of a plasmid in virulence of Campylobacter jejuni. Infect. Immun. 2000, 68:4384-4390.
11. Bacon D.J., Szymanski C.M., Burr D.H., Silver R.P., Alm R.A., Guerry P. Aphase-variable capsule is involved in virulence of Campylobacter jejuni 81-176. Mol. Microbiol. 2001, 40:769-777.
12. Bang D.D., Scheutz F., Ahrens P., Pedersen K., Blom J., Madsen M. Prevalence of cytolethal distending toxin (cdt) genes and CDT production in Campylobacter spp. isolated from Danish broilers. J.Med. Microbiol. 2001, 50:1087-1094.
13. Bang D.D., Scheutz F., Gradel K.O., Nielsen E.M., Pedersen K., Engberg J., Gerner-Smidt P., Handberg K., Madsen M. Detection of seven virulence and toxin genes of Campylobacter jejuni and Campylobacter coli isolates from different sources and cytolethal distending toxin production suggest potential diversity of pathogenic properties among isolates. Gen. Lett. 2003, 2:62-72.
14. Batz M.B., Hoffman S., Glenn Morris J. Ranking the Risks: the 10 Pathogen-food Combinations with the Greatest Burden on Public Health 2011, Emerging Pathogens Institute, University of Florida, Florida, USA.
15. Bingham-Ramos L.K., Hendrixson D.R. Characterization of two putative cytochrome c peroxidases of Campylobacter jejuni involved in promoting commensal colonization of poultry. Infect. Immun. 2008, 76:1105-1114.
16. Biswas D., Fernando U.M., Reiman C.D., Willson P.J., Townsend H.G., Potter A.A., Allan B.J. Correlation between invitro secretion of virulence-associated proteins of Campylobacter jejuni and colonization of chickens. Curr. Microbiol. 2007, 54:207-212.
17. Bras A.M., Chatterjee S., Wren B.W., Newell D.G., Ketley J.M. Anovel Campylobacter jejuni two-component regulatory system important for temperature- dependent growth and colonization. J.Bacteriol. 1999, 181:3298-3302.
18. Buelow D.R., Christentsen J.E., Neal-McKinney J.M., Konkel M.E. Campylobacter jejuni survival within human epithelial cells is enhanced by the secreted protein CiaI. Mol. Microbiol. 2011, 80:1296-1312.
19. Butzler J.P., Oosterom J. Campylobacter; pathogenicity and significance in foods. Int. J. Food Microbiol. 1991, 12:1-8.
20. Byrne C.M., Clyne M., Bourke B. Campylobacter jejuni adhere to and invade chicken intestinal epithelial cells invitro. Microbiol. 2007, 153:561-569.
21. Carrillo C.D., Taboada E., Nash J.H.E., Lanthier P., Kelly J., Lau P.C., Verhulp R., Mykytczuk O., Sy J., Findlay W.A., Amoako K., Gomis S., Willson P., Austin J.W., Potter A., Babiuk L., Allan B., Szymanski C.M. Genome-wide expression analyses of Campylobacter jejuni NCTC11168 reveals coordinate regulation of motility and virulence by flhA. J.Biol. Chem. 2004, 279:20317-20338.
22. Carvalho A.C., Ruiz-Palacios G.M., Ramos-Cervantes P., Cervantes L.E., Jiang X., Pickering L.K. Molecular characterisation of invasive and noninvasive Campylobacter jejuni and Campylobacter coli isolates. J.Clin. Microbiol. 2001, 39:1353-1359.
23. Cawthraw S.A., Wassenaar T.M., Ayling R., Newell D.G. Increased colonization potential of Campylobacter jejuni strain 81116 after passage through chickens and its implication on the rate of transmission within flocks. Epidemiol. Infect. 1996, 117:213-215.
24. Chang C., Miller J.F. Campylobacter jejuni colonization of mice with limited enteric flora. Infect. Immun. 2006, 74:5261-5271.
25. Champion O.L., Gaunt M.W., Gundogdu O., Elmi A., Witney A.A., Hinds J., Dorrell N., Wren B.W. Comparative phylogenomics of the food-borne pathogen Campylobacter jejuni reveals genetic markers predictive of infection source. Proc. Nat. Acad. Sci. U. S. A. 2005, 102:16043-16048.
26. Chaveerach P., ter Huurne A.A., Lipman L.J., van Knapen F. Survival and resuscitation of ten strains of Campylobacter jejuni and Campylobacter coli under acid conditions. Appl. Environ. Microbiol. 2003, 69:711-714.
27. Christensen J.E., Pacheco S.A., Konkel M.E. Identification of a Campylobacter jejuni - secreted protein required for maximal invasion of host cells. Mol. Microbiol. 2009, 73:650-662.
28. Coward C., van Diemen P.M., Conlan A.J.K., Gog J.R., Stevens M.P., Jones M.A., Maskell D.J. Competing isogenic Campylobacter strains exhibit variable population structures invivo. Appl. Environ. Microbiol. 2008, 74:3857-3867.
29. Dasti J.I., Tareen A.M., Lugert R., Zautner A.E., Gro B.U. Campylobacter jejuni; A brief overview on pathogenicity-associated factors and disease mediated mechanisms. Int. J. Med. Microbiol. 2010, 300:205-211.
30. Dekker N. Outer-membrane phospholipase A: known structure, unknown biological function. Mol. Microbiol. 2000, 35:711-717.
31. European Food Safety Authority (EFSA) Scientific opinion on quantification of the risk posed by broiler meat to human campylobacteriosis in the EU. EFSA J. 2010, 8:1437-1526.
32. European Food Safety Authority (EFSA) Analysis of the baseline survey on the prevalence of Campylobacter in broiler batches and of Campylobacter and Salmonella on broiler carcasses in the EU, 2008. EFSA J. 2010, 8:1503-1602.
33. Eucker T.P., Konkel M.E. The cooperative action of bacterial fibronectin-binding proteins and secreted proteins promote maximal Campylobacter jejuni invasion of host cells by stimulating membrane ruffling. Cell. Microbiol. 2012, 14:226-238.
34. European Food Safety Authority (EFSA) Scientific opinion on Campylobacter in broiler meat production: control options and performance objectives and/or targets at different stages of the food chain. EFSA J. 2011, 9(4). 2105, 1-141.
35. European Food Safety Authority (EFSA) Trends and sources of zoonoses and zoonotic agents and foodborne outbreaks in 2010. EFSA J. 2012, 10:1-442.
36. Fernández H., Vera F., Villanueva M.P., García A. Occurrence of Campylobacter species in healthy well-nourished and malnourished children. Braz. J. Microbiol. 2008, 39:1-310.
37. Ferrero R.L., Lee A. Motility of Campylobacter jejuni in a viscous environment: comparison with conventional rod-shaped bacteria. J.Gen. Microbiol. 1988, 134(1):53-59.
38. Fernando U., Biswas D., Allan B., Willson P., Potter A.A. Influence of Campylobacter jejuni fliA, rpoN, and flgK genes on colonization of the chicken gut. Int. J. Food Microbiol. 2007, 118:194-200.
39. Flanagan R.C., Neal-McKinney J.M., Dhillon A.S., Miller W.G., Konkel M.E. Examination of Campylobacter jejuni putative adhesins leads to the identification of a new protein, designated FlpA, required for chicken colonization. Infect. Immun. 2009, 77:2399-2407.
40. Foster G., Holmes B., Steigerwalt A.G., Lawson P.A., Thorne P., Byrer D.E., Ross H.M., Xerry J., Thompson P.M., Collins M.D. Campylobacter insulaenigrae sp. nov., isolated from marine mammals. Int. J. Syst. Evol. Microbiol. 2004, 54:2369-2373.
41. Garénaux A., Jugiau F., Rama F., Jonge R., Denis M., Federighi M., Ritz M. Survival of Campylobacter jejuni strains from different origins under oxidative stress conditions: effect of temperature. Curr. Microbiol. 2008, 56:293-297.
42. Gaynor E.C., Wells D.H., MacKichan J.K., Falkow S. The Campylobacter jejuni stringent response controls specific stress survival and virulence-associated phenotypes. Mol. Microbiol. 2005, 56(1):8-27.
43. Ge Z., Schauer D.B., Fox J.G. Invivo virulence properties of bacterial cytolethal-distending toxin. Cell. Microbiol. 2008, 10:1599-1607.
44. 13C NMR analysis. J.Biol. Chem. 2000, 275:3896-3906.
45. Gibreel A., Taylor D.E. Macrolide resistance in Campylobacter jejuni and Campylobacter coli. J.Antimicrob. Chemother. 2006, 58:243-255.
46. Golden N.J., Acheson D.W. Identification of motility and autoagglutination Campylobacter jejuni mutants by random transposon mutagenesis. Infect. Immun. 2002, 70:1761-1771.
47. Guerry P., Ewing C.P., Hickey T.E., Prendergast M.M., Moran A.P. Sialylation of lipooligosaccharide core affects immunogenicity and serum resistance of Campylobacter jejuni. Infect. Immun. 2000, 68:6656-6662.
48. Guerry P., Szymanski C.M., Prendergast M.M., Hickey T.E., Ewing C.P., Pattarini D.L., Moran A.P. Phase variation of Campylobacter jejuni 81-176 lipooligosaccharide affects ganglioside mimicry and invasiveness invitro. Infect. Immun. 2002, 70:787-793.
49. Guerry P. Campylobacter flagella: not just for motility. Trends Microbiol. 2007, 15:456-461.
50. Guccione E., Del Rocio Leon-Kempis M., Pearson B.M., Hitchin E., Mulholland F., van Diemen P.M., Stevens M.P., Kelly D.J. Amino-acid dependent growth of Campylobacter jejuni: key roles for aspartase (AspA) under microaerobic and oxygen-limited conditions and identification of AspB (Cj0762), essential for growth on glutamate. Mol. Microbiol. 2008, 69:77-93.
51. Guo B., Wang Y., Shi F., Barton Y.W., Plummer P., Reynolds D.L., Nettleton D., Grinnage-Pulley T., Lin J., Zhang Q. CmeR functions as a pleiotropic regulator and is required for optimal colonization of Campylobacter jejuni invivo. J.Bacteriol. 2008, 190:1879-1890.
52. Habib I., Louwen R., Uyttendaele M., Houf K., Vandenberg O., Nieuwenhuis E.E., Miller W.G., van Belkum A., De Zutter L. Correlation between genotypic diversity, lipooligosaccharide gene locus class variation, and caco-2 cell invasion potential of Campylobacter jejuni isolates from chicken meat and humans: contribution to virulotyping. Appl. Environ. Microbiol. 2009, 75:4277-4288.
53. Hamer R., Chen P.Y., Armitage J.P., Reinert G., Deane C.M. Deciphering chemotaxis pathways using cross species comparisons. BMC Syst. Biol. 2010, 4(3). Available online at:. http://www.biomedcentral.com/content/pdf/1752-0509-4-3.pdf.
54. Hartley-Tassell L.E., Shewell L.K., Day C.J., Wilson J.C., Sandhu R., Ketley J.M., Korolik V. Identification and characterization of the aspartate chemosensory receptor of Campylobacter jejuni. Mol. Microbiol. 2010, 75:710-730.
55. Harvey P., Leach S. Analysis of coccal cell formation by Campylobacter jejuni using continuous culture techniques, and the importance of oxidative stress. J.Appl. Microbiol. 1998, 85:398-404.
56. Hazeleger W.C., Wouters J.A., Rombouts F.M., Abee T. Physiological activity of Campylobacter jejuni far below the minimal growth temperature. Appl. Environ. Microbiol. 1998, 64:3917-3922.
57. Hendrixson D.R. Aphase-variable mechanism controlling the Campylobacter jejuni FlgR response regulator influences commensalism. Mol. Microbiol. 2006, 61:1646-1659.
58. Hendrixson D.R., DiRita V.J. Identification of Campylobacter jejuni genes involved in commensal colonization of the chick gastrointestinal tract. Mol. Microbiol. 2004, 52:471-484.
59. Hermans D., Van Deun K., Martel A., Immerseel F., Messens W., Heyndrickx M., Haesebrouck F., Pasmans F. Colonization factors of Campylobacter jejuni in the chicken gut. Vet. Res. 2011, 42(82). Available at:. http://www.veterinaryresearch.org/content/pdf/1297-9716-42-82.pdf.
60. Hermans D., Pasmans F., Messens W., Martel A., Van Immerseel F., Rasschaert G., Heyndrickx M., Van Deun K., Haesebrouck F. Poultry as a host for the zoonotic pathogen Campylobacter jejuni. Vector Borne Zoonotic Dis. 2012, 12:89-98.
61. Hofreuter D., Tsai J., Watson R.O., Novik V., Altman B., Benitez M., Clark C., Perbost C., Jarvie T., Du L., Galan J.E. Unique features of a highly pathogenic Campylobacter jejuni strain. Infect. Immun. 2006, 74:4694-4707.
62. Humphrey T., O'Brien S., Madsen M. Campylobacters as zoonotic pathogens: a food production perspective. Int. J. Food Microbiol. 2007, 117:237-257.
63. Hugdahl M.B., Beery J.T., Doyle M.P. Chemotactic behavior of Campylobacter jejuni. Infect. Immun. 1988, 56:1560-1566.
64. Humphrey T.J., Mason M., Martin K. The isolation of Campylobacter jejuni from contaminated surfaces and its survival in diluents. Int. J. Food Microbiol. 1995, 26:295-303.
65. Ishikawa T., Mizunoe Y., Kawabata S., Takade A., Harada M., Wai S.N., Yoshida S. The iron-binding protein Dps confers hydrogen peroxide stress resistance to Campylobacter jejuni. J.Bacteriol. 2003, 185:1010-1017.
66. Jagannathan A., Constantinidou C., Penn C.W. Roles of rpoN, fliA, and flgR in expression of flagella in Campylobacter jejuni. J.Bacteriol. 2001, 183:2937-2942.
67. Jagannathan A., Penn C. Motility in Campylobacter. Molecular and Cellular Biology 2005, 331-347. Horizon Bioscience, Norfolk. J.M. Ketley, M.E. Konkel (Eds.).
68. Jin S., Joe A., Lynett J., Hani E.K., Sherman P., Chan V.L. JlpA, a novel surface-exposed lipoprotein specific to Campylobacter jejuni, mediates adherence to host epithelial cells. Mol. Microbiol. 2001, 39:1225-1236.
69. Jin S., Song Y.C., Emili A., Sherman P.M., Chan V.L. JlpA of Campylobacter jejuni interacts with surface-exposed heat shock protein 90 and triggers signalling pathways leading to the activation of NF-kabbaB and p38 MAP kinase in epithelial cells. Cell. Microbiol. 2003, 5:165-174.
70. Jones D.M., Sutcliffe E.M., Rios R., Fox A.J., Curry A. Campylobacter jejuni adapts to aerobic metabolism in the environment. J.Med. Microbiol. 1993, 38:145-150.
71. Jones M.A., Marston K.L., Woodall C.A., Maskell D.J., Linton D., Karlyshev A.V., Dorrell N., Wren B.W., Barrow P.A. Adaptation of Campylobacter jejuni NCTC11168 to high-level colonization of the avian gastrointestinal tract. Infect. Immun. 2004, 72(7):3769-3776.
72. Kakuda T., DiRita V.J. Cj1496c encodes a Campylobacter jejuni glycoprotein that influences invasion of human epithelial cells and colonization of the chick gastrointestinal tract. Infect. Immun 2006, 74:4715-4723.
73. Kale A., Phansopa C., Suwannachart C., Craven C.J., Rafferty J.B., Kelly D.J. The virulence factor PEB4 (CJ0596) and the periplasmic protein Cj1289 are two structurally related SurA-like chaperones in the human pathogen Campylobacter jejuni. J.Biol. Chem. 2011, 286:21254-21265.
74. Kanungpean D., Kakuda T., Takai S. Participation of CheR and CheB in chemosensory response of Campylobacter jejuni. Microbiology 2011, 157:1279-1289.
75. Karlyshev A.V., Linton D., Gregson N.A., Lastovica A.J., Wren B.W. Genetic and biochemical evidence of a Campylobacter jejuni capsular polysaccharide that accounts for Penner serotype specificity. Mol. Microbiol. 2000, 35:529-541.
76. Karlyshev A.V., Everest P., Linton D., Cawthraw S., Newell D.G., Wren B.W. The Campylobacter jejuni general glycosylation system is important for attachment to human epithelial cells and in the colonization of chicks. Microbiology 2004, 150:1957-1964.
77. Karlyshev A.V., Ketley J.M., Wren B.W. The Campylobacter jejuni glycome. FEMS Microbiol. Rev. 2005, 29:377-390.
78. Kervella M., Pages J.M., Pei Z., Grollier G., Blaser M.J., Fauchere J.L. Isolation and characterisation of two Campylobacter glycine-extracted proteins that bind to HeLa cell membranes. Infect. Immun. 1993, 61:3440-3448.
79. Ketley J.M. Pathogenesis of enteric infection by Campylobacter. Microbiology 1997, 143:5-21.
80. Klancnik A., Bernarda G., Jamnik P., Vuckovic D., Abram M., Mozina S. Stress response and pathogenic potential of Campylobacter jejuni cells exposed to starvation. Res. Microbiol. 2009, 160(5):345-352.
81. Konkel M.E., Garvis S.G., Tipton S.L., Anderson D.E., Cieplak W. Identification and molecular cloning of a gene encoding a fibronectin-binding protein (CadF) from Campylobacter jejuni. Mol. Microbiol. 1997, 24:953-963.
82. Konkel M.E., Kim B.J., Klena J.D., Young C.R., Ziprin R. Characterization of thermal stress response of Campylobacter jejuni. Infect. Immun. 1998, 66:362-366.
83. Konkel M.E., Kim B.J., Rivera-Amill V., Garvis S.G. Bacterial secreted proteins are required for the internalization of Campylobacter jejuni into cultured mammalian cells. Mol. Microbiol. 1999, 32:691-701.
84. Konkel M.E., Klena J.D., Rivera-Amill V., Monteville M.R., Biswas D., Raphael B., Mickelson J. Secretion of virulence proteins from Campylobacter jejuni is dependent on a functional flagellar export apparatus. J.Bacteriol. 2004, 186:3296-3303.
85. Konkel M.E., Larson C.L., Flanagan R.C. Campylobacter jejuni FlpA binds fibronectin and is required for maximal host cell adherence. J.Bacteriol. 2010, 192:68-76.
86. Krause-Gruszczynska M., van Alphen L.B., Oyarzabal O.A., Alter T., Hänel I., Schliephake A., König W., van Putten J.P., Konkel M.E., Backert S. Expression patterns and role of the CadF protein in Campylobacter jejuni and Campylobacter coli. FEMS Microbiol. Lett. 2007, 274:9-16.
87. Lertsethtakarn P., Ottemann K.M., Hendrixson D.R. Motility and chemotaxis in Campylobacter and Helicobacter. Annu. Rev. Microbiol. 2011, 65:389-410.
88. Louwen R., Heikema A., van Belkum A., Ott A., Gilbert M., Ang W., Endtz H.P., Bergman M.P., Nieuwenhuis E.E. The sialylated lipooligosaccharide outer core in Campylobacter jejuni is an important determinant for epithelial cell invasion. Infect. Immun. 2008, 76(10):4431-4438.
89. Lin J., Michel L.O., Zhang Q. CmeABC functions as a multidrug efflux system in Campylobacter jejuni. Antimicrob. Agents Chemother. 2002, 46:2124-2131.
90. 1-like lipo-oligosaccharide of Campylobacter jejuni. Mol. Microbiol. 2000, 37:501-514.
91. Marchant J., Wren B., Ketley J. Exploiting genome sequence: predictions for mechanisms of Campylobacter chemotaxis. Trends Microbiol. 2002, 10:155-159.
92. McFarland B.A., Neill S.D. Profiles of toxin production by thermophilic Campylobacter of animal origin. Vet. Microbiol. 1992, 30:257-266.
93. Meade K.G., Nirciandi F., Cahalane S., Reiman C., Allan B., O'Farrelly C. Comparative invivo infection models yield insights on early host immune response to Campylobacter in chickens. Immunogenetics 2009, 61:101-110.
94. Mihaljevic R.R., Sikic M., Klancnik A., Brumini G., Mozina S.S., Abram M. Environmental stress factors affecting survival and virulence of Campylobacter jejuni. Microb. Pathog. 2007, 43:120-125.
95. Min T., Vedadi M., Watson D.C., Wasney G.A., Munger C., Cygler M., Matte A., Young N.M. Specificity of Campylobacter jejuni adhesin PEB3 for phosphates and structural differences among its ligand complexes. Biochem. 2009, 48:3057-3067.
96. Mohammed K.A.S., Miles R.J., Halablab M.A. The pattern and kinetics of substrate metabolism of Campylobacter jejuni and Campylobacter coli. Lett. Appl. Microbiol. 2004, 39:261-266.
97. Monteville M.R., Yoon J.E., Konkel M.E. Maximal adherence and invasion of INT 407 cells by Campylobacter jejuni requires the CadF outer-membrane protein and microfilament reorganization. Microbiology 2003, 149:153-165.
98. Moore J.E. Bacterial dormancy in Campylobacter: abstract theory or cause for concern?. Int. J. Food Sci. Technol. 2001, 36:593-600.
99. Myers J.D., Kelly D.J. Respiratory electron transport in Helicobacter and Campylobacter. Diversity of Prokaryotic Respiratory Systems 2005, vol. 2:63-80. Kluwer Academic Publishers, Dordrecht, The Netherlands. D. Zannoni (Ed.).
100. Nachamkim I., Yang X.-H., Stern N.J. Role of Campylobacter jejuni flagella as colonization factors for three days old chicks: analysis with flagella mutants. Appl. Environ. Microbiol. 1993, 59:1269-1273.
101. Novik V., Hofreuter D., Galan J.E. Characterisation of a Campylobacter jejuni VirK protein homolog as a novel virulence determinant. Infect. Immun. 2009, 77:5428-5436.
102. O'Donovan D.J., Fernandes C.J. Mitochondrial glutathione and oxidative stress: implications for pulmonary oxygen toxicity in premature infants. Mol. Genet. Metab. 2000, 1:352-358.
103. On S.L.W. Taxonomy of Campylobacter, Arcobacter, Helicobacter and related bacteria: current status, future prospects and immediate concerns. J.Appl. Microbiol. 2001, 90:1S-15S.
104. Oosterom J., de Wilde G.J.A., de Boer E., de Blaauw L.H., Karman H. Survival of Campylobacter jejuni during poultry processing and pig slaughtering. J.Food Prot. 1983, 46:702-706.
105. Palyada K., Threadgill D., Stintzi A. Iron acquisition and regulation in Campylobacter jejuni. J.Bacteriol. 2004, 186(14):4714-4729.
106. Palyada K., Sun Y.Q., Flint A., Butcher J., Naikare H., Stintzi A. Characterization of the oxidative stress stimulon and PerR regulon of Campylobacter jejuni. BMC Genomics 2009, 10:481. Available at:. http://www.biomedcentral.com/content/pdf/1471-2164-10-481.pdf.
107. Park S.F. The physiology of Campylobacter species and its relevance to their role as foodborne pathogens. Int. J. Food Microbiol. 2002, 74:177-188.
108. Park S.F. Campylobacter jejuni stress responses during survival in the food chain and colonization. Campylobacter Moecular and Cellular Biology 2005, Horison Bioscience, Norfolk, U.K. J.M. Ketley, M.E. Konkel (Eds.).
109. Park S.F., Richardson P.T. Molecular characterization of a Campylobacter jejuni lipoprotein with homology to periplasmic siderophore-binding proteins. J. Bacteriol 1995, 177:2259-2264.
110. Parkhill J., Wren B.W., Mungall K., Ketley J.M., Churcher C., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quai l M.A., Rajandream M.A., Rutherford K.M., van Vliet A.H., Whitehead S., Barrell B.G. The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences. Nature 2000, 403:665-668.
111. Patriarchi A., Maunsell B., O'Mahony E., Fox A., Fanning S., Bolton D. Prevalence of Campylobacter spp. in a subset of intensive poultry flocks in Ireland. Lett. Appl. Microbiol. 2009, 49(3):305-310.
112. Pei Z., Blaser M.J. PEB1, the major cell-binding factor of Campylobacter jejuni, is a homolog of the binding component in Gram-negative nutrient transport systems. J.Biol. Chem. 1993, 268:18717-18725.
113. Pickett C.L., Pesci E.C., Cottle D.L., Russell G., Erdem A.N., Zeytin H. Prevalence of cytolethal distending toxin production in Campylobacter jejuni and relatedness of Campylobacter sp. cdtB genes. Infect. Immun. 1996, 64:2070-2078.
114. Pickett C.L., Whitehouse C.A. The cytolethal distending toxin family. Trends Microbiol. 1999, 7:292-297.
115. Poly F., Ewing C., Goon S., Hickey T.E., Rockabrand D., Majam G., Lee L., Phan J., Savarino N.J., Guerry P. Heterogeneity of a Campylobacter jejuni protein that is secreted through the flagellar filament. Infect. Immun. 2007, 75:3859-3867.
116. Poly F., Guerry P. Pathogenesis of Campylobacter. Curr. Opin. Gastroenterol. 2008, 24:27-31.
117. Poly F., Serichatalergs O., Schulman M., Ju J., Cates C.N., Kanipes M.I., Mason C., Guerry P. Discrimination of major capsular types of Campylobacter jejuni by multiplex PCR. J. Clin. Microbiol. 2011, 49:1750-1757.
118. Purdy D., Cawthraw S., Dickinson J.H., Newell D.G., Park S.F. Generation of a superoxide dismutase (SOD)-deficient mutant of Campylobacter coli: evidence for the significance of SOD in Campylobacter survival and colonization. Appl. Environ. Microbiol. 1999, 65:2540-2546.
119. Quinones B., Miller W.G., Bates A.H., Mandrell R.E. Autoinducer-2 production in Campylobacter jejuni contributes to chicken colonization. Appl. Environ. Microbiol. 2009, 75:281-285.
120. Ridley A.M., Toszeghy M.J., Cawthraw S.A., Wassenaar T.M., Newell D.G. Genetic instability is associated with changes in the colonization potential of Campylobacter jejuni in the avian intestine. J.Appl. Microbiol. 2008, 105:95-104.
121. Rivera-Amill V., Kim B.J., Seshu J., Konkel M.E. Secretion of the virulence-associated Campylobacter invasion antigens from Campylobacter jejuni requires a stimulatory signal. J.Infect. Dis. 2001, 183:1607-1616.
122. Roberts I.S. The biochemistry and genetics of capsular polysaccharide production in bacteria. Ann. Rev. Microbiol. 1996, 50:285-315.
123. Schulze F., Hänel I., Borrmann E. Formation of cytotoxins by enteric Campylobacter in humans and animals. Zentralbl. Bakteriol. 1998, 288:225-236.
124. Silva J., Leite D., Fernandes M., Mena C., Gibbs P.A., Teixeira P. Campylobacter spp. as a foodborne pathogen: a review. Front. Microbiol. 2011, 2:200. Available at:. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180643/pdf/fmicb-02-00200.pdf.
125. Smith C.K., Abuoun M., Cawthraw S.A., Humphrey T.J., Rothwell L., Kaiser P., Barrow P.A., Jones M.A. Campylobacter colonization of the chicken induces a proinflammatory response in mucosal tissues. FEMS. Immunol. Med. Microbiol. 2008, 254:114-121.
126. Sommerlad S.M., Hendrixson D.R. Analysis of the roles of FlgP and FlgQ in flagellar motility of Campylobacter jejuni. J.Bacteriol. 2007, 189:179-186.
127. Song Y.C., Jin S., Louie H., Ng D., Lau R., Zhang Y., Weerasekera R., Al Rashid S., Ward L.A., Der S.D., Chan V.L. FlaC, a protein of Campylobacter jejuni TGH9011 (ATCC43431) secreted through the flagellar apparatus, binds epithelial cells and influences cell invasion. Mol. Microbiol. 2004, 53:541-553.
128. Stern N.J., Bailey J.S., Blankenship L.C., Cox N.A., McHan F. Colonization characteristics of Campylobacter jejuni in chick ceca. Avian Dis. 1988, 32:330-334.
129. Storz G., Imlay J.A. Oxidative stress. Curr. Opin. Microbiol. 1999, 2:188-194.
130. Szymanski C.M., Michael F.S., Jarrell H.C., Li J., Gilbert M., Larocque S., Vinogradov E., Brisson J.R. Detection of conserved N-linked glycans and phase-variable lipopolysaccharides and capsules from Campylobacter cells by mass spectrometry and high resolution magic angle spinning NMR spectroscopy. J.Biol. Chem. 2003, 278:24,509-24,520.
131. Van Deun K., Haesebrouck F., Heyndrickx M., Favoreel H., Dewulf J., Ceelen L., Dumez L., Messens W., Leleu S., Van Immerseel F., Ducatelle R., Pasmans F. Virulence properties of Campylobacter jejuni isolates of poultry and human origin. J.Med. Microbiol. 2007, 56:1284-1289.
132. Vegge C.S., Brondsted L., Li Y.P., Bang D.D., Ingmer H. Energy taxis drives Campylobacter jejuni toward the most favorable conditions for growth. Appl. Environ. Microbiol. 2009, 75:5308-5314.
133. Velayudhan J., Jones M.A., Barrow P.A., Kelly D.J. LSerine catabolism via an oxygen-labile L-serine dehydratase is essential for colonization of the avian gut by Campylobacter jejuni. Infect. Immun. 2004, 72:260-268.
134. Wadhams G.H., Armitage J.P. Making sense of it all: bacterial chemotaxis. Nat. Rev. Mol. Cell Biol. 2004, 5:1024-1037.
135. Wang G., Maier R.J. An NADPH quinone reductase of Helicobacter pylori plays an important role in oxidative stress resistance and host colonization. Infect. Immun. 2004, 72(3):1391-1396.
136. Wassenaar T.M., Fry B.N., Van der Zeijst B.A.M. Genetic manipulation of Campylobacter: evaluation of natural transformation and electro-transformation. Gene 1993, 132:131-135.
137. Weingarten R.A., Grimes J.L., Olson J.W. Role of Campylobacter jejuni respiratory oxidases and reductases in host colonization. Appl. Environ. Microbiol. 2008, 74:1367-1375.
138. Westfall H.N., Rolins D.M., Weiss E. Substrate utilization by Campylobacter jejuni and Campylobacter coli. Appl. Environ. Microbiol. 1986, 52:700-705.
139. Woodall C.A., Jones M.A., Barrow P.A., Hinds J., Marsden G.L., Kelly D.J., Dorrell N., Wren B.W., Maskell D.J. Campylobacter jejuni gene expression in the chick cecum: evidence for adaptation to a low-oxygen environment. Infect. Immun. 2005, 73:5278-5285.
140. Wösten M., Wagenaar M.J.A., Van Putten J.P. The FlgS/FlgR two-component signal transduction system regulates the fla regulon in Campylobacter jejuni. J.Biol. Chem. 2004, 279:16214-16222.
141. Wuichet K., Alexander R.P., Zhulin I.B. Comparative genomic and protein sequence analyses of a complex system controlling bacterial chemotaxis. Methods Enzymol. 2007, 422:1-31.
142. Xu F., Zeng X., Haigh R.D., Ketley J.M., Lin J. Identification and characterization of a new ferric enterobactin receptor, CfrB, in Campylobacter. J.Bacteriol. 2010, 192:4425-4435.
143. Yamasaki M., Igimi S., Katayama Y., Yamamoto S., Amano F. Identification of an oxidative stress-sensitive protein from Campylobacter jejuni, homologous to rubredoxin oxidoreductase/rubrerythrin. FEMS Microbiol. Lett. 2004, 235:57-63.
144. Yao R., Burr D.H., Doig P., Trust T.J., Niu H., Guerry P. Isolation of motile and non-motile insertional mutants of Campylobacter jejuni: the role of motility in adherence and invasion of eukaryotic cells. Mol. Microbiol. 1994, 14:883-893.
145. Yao R., Burr D.H., Guerry P. CheY-mediated modulation of Campylobacter jejuni virulence. Mol. Microbiol. 1997, 23:1021-1031.
146. Young N.M., Brisson J.R., Kelly J., Watson D.C., Tessier L., Lanthier P.H., Jarrell H.C., Cadotte N., St Michael F., Aberg E., Szymanski C.M. Structure of the N-limked glycan present on multiple glycoproteins in the Gram-negative bacterium, Campylobacter jejuni. J.Biol. Chem. 2002, 227:42530-42539.
147. Yun J., Jeon B., Barton Y.W., Plummer P., Zhang Q., Sangryeol R. Role of the DksA-like protein in the pathogenesis and diverse metabolic activity of Campylobacter jejuni. J.Bacteriol. 2008, 190:4512-4520.
148. Ziprin R.L., Young C.R., Stanker L.H., Hume M.E., Konkel M.E. The absence of ceca colonization of chicks by mutant of Campylobacter jejuni not expressing bacterial fibronectin-binding protein. Avian Dis. 1999, 43:586-589.
149. Ziprin R.L., Young C.R., Byrd J.A., Stanker L.H., Hume M.E., Gray S.A., Kim B.J., Konkel M.E. Role of Campylobacter jejuni potential virulence genes in cecal colonization. Avian Dis. 2001, 45:549-557.
150. Zhang M.J., Xiao D., Zhao F., Gu Y.X., Meng F.L., He L.H., Ma G.Y., Zhang J.Z. Comparative proteomic analysis of Campylobacter jejuni cultured at 37°C and 42°C. Jpn. J. Infect. Dis. 2009, 62:356-361.