메뉴 건너뛰기




Volumn 98, Issue 20, 2014, Pages 8685-8695

Effects of antimicrobial peptide L-K6, a temporin-1CEb analog on oral pathogen growth, Streptococcus mutans biofilm formation, and anti-inflammatory activity

Author keywords

Amphibian; Antimicrobial peptide; Biofilm; Dental caries; Inflammation; Lipopolysaccharide

Indexed keywords

CELL DEATH; MICROORGANISMS; PEPTIDES;

EID: 84920256643     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-014-5927-9     Document Type: Article
Times cited : (65)

References (44)
  • 1
    • 51949093305 scopus 로고    scopus 로고
    • Characteristics of biofilm formation by Streptococcus mutans in the presence of saliva
    • PID: 18625741, COI: 1:CAS:528:DC%2BD1cXhtVyrsbzK
    • Ahn SJ, Wen ZT, Brady LJ, Burne RA (2008) Characteristics of biofilm formation by Streptococcus mutans in the presence of saliva. Infect Immun 76:4259–4268
    • (2008) Infect Immun , vol.76 , pp. 4259-4268
    • Ahn, S.J.1    Wen, Z.T.2    Brady, L.J.3    Burne, R.A.4
  • 2
    • 70549108098 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes
    • PID: 19643762, COI: 1:CAS:528:DC%2BD1MXhsFeksLfL
    • Alhede M, Bjarnsholt T, Jensen PO (2009) Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes. Microbiology 155:3500–3508
    • (2009) Microbiology , vol.155 , pp. 3500-3508
    • Alhede, M.1    Bjarnsholt, T.2    Jensen, P.O.3
  • 3
    • 35848962760 scopus 로고    scopus 로고
    • Activity of an antimicrobial peptide mimetic against planktonic and biofilm cultures of oral pathogens
    • PID: 17785509, COI: 1:CAS:528:DC%2BD2sXht1ygtLrP
    • Beckloff N, Laube D, Castro T, Furgang D, Park S, Perlin D, Clements D, Tang H (2007) Activity of an antimicrobial peptide mimetic against planktonic and biofilm cultures of oral pathogens. Antimicrob Agents Chemother 51:4125–4132
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 4125-4132
    • Beckloff, N.1    Laube, D.2    Castro, T.3    Furgang, D.4    Park, S.5    Perlin, D.6    Clements, D.7    Tang, H.8
  • 5
    • 0348230977 scopus 로고    scopus 로고
    • The application of biofilm science to the study and control of chronic bacterial infections
    • Costerton W, Veeh R, Shirtliff M, Pasmore M, Post C, Ehrlich G (2003) The application of biofilm science to the study and control of chronic bacterial infections. J Clin Invest 112:146–147
    • (2003) J Clin Invest , vol.112 , pp. 146-147
    • Costerton, W.1    Veeh, R.2    Shirtliff, M.3    Pasmore, M.4    Post, C.5    Ehrlich, G.6
  • 6
    • 75549084426 scopus 로고    scopus 로고
    • Anti-microbial peptides for plaque control and beyond
    • PID: 19998654
    • Gilmore K, Chen P, Leung KP (2009) Anti-microbial peptides for plaque control and beyond. J Calif Dent Assoc 37:779–788
    • (2009) J Calif Dent Assoc , vol.37 , pp. 779-788
    • Gilmore, K.1    Chen, P.2    Leung, K.P.3
  • 7
    • 0038505147 scopus 로고    scopus 로고
    • The contribution of interleukin-1 and tumor necrosis factor to periodontal tissue destruction
    • PID: 12710761, COI: 1:CAS:528:DC%2BD3sXlvFCjtbs%3D
    • Graves DT, Cochran D (2003) The contribution of interleukin-1 and tumor necrosis factor to periodontal tissue destruction. J Periodontol 74:391–401
    • (2003) J Periodontol , vol.74 , pp. 391-401
    • Graves, D.T.1    Cochran, D.2
  • 8
    • 0019255349 scopus 로고
    • Biology, immunology, and cariogenicity of Streptococcus mutans
    • PID: 6446023, COI: 1:CAS:528:DyaL3cXks1Gnu7c%3D
    • Hamada S, Slade HD (1980) Biology, immunology, and cariogenicity of Streptococcus mutans. Microbiol Rev 44:331–384
    • (1980) Microbiol Rev , vol.44 , pp. 331-384
    • Hamada, S.1    Slade, H.D.2
  • 9
    • 50249142996 scopus 로고    scopus 로고
    • Antimicrobial therapy in periodontitis: the use of systemic antimicrobials against the subgingival biofilm
    • PID: 18724841, COI: 1:CAS:528:DC%2BD1cXhtFKit7jM
    • Herrera D, Alonso B, Leon R, Roldan S, Sanz M (2008) Antimicrobial therapy in periodontitis: the use of systemic antimicrobials against the subgingival biofilm. J Clin Periodontol 35:45–66
    • (2008) J Clin Periodontol , vol.35 , pp. 45-66
    • Herrera, D.1    Alonso, B.2    Leon, R.3    Roldan, S.4    Sanz, M.5
  • 11
    • 61349169039 scopus 로고    scopus 로고
    • AMPed Up immunity: how antimicrobial peptides have multiple roles in immune defense
    • PID: 19217824, COI: 1:CAS:528:DC%2BD1MXivVertr8%3D
    • Lai Y, Gallo RL (2009) AMPed Up immunity: how antimicrobial peptides have multiple roles in immune defense. Trends Immunol 30:131–141
    • (2009) Trends Immunol , vol.30 , pp. 131-141
    • Lai, Y.1    Gallo, R.L.2
  • 12
    • 9244260502 scopus 로고    scopus 로고
    • Streptococcus mitis cell walls and lipopolysaccharide induce lethality in D-galactosamine-sensitized mice by a tumor necrosis factor-dependent pathway
    • PID: 8613401
    • Le Roy D, Morand P, Lengacher S, Celio M, Grau GE, Glauser MP, Heumann D (1996) Streptococcus mitis cell walls and lipopolysaccharide induce lethality in D-galactosamine-sensitized mice by a tumor necrosis factor-dependent pathway. Infect Immun 64:1846–1849
    • (1996) Infect Immun , vol.64 , pp. 1846-1849
    • Le Roy, D.1    Morand, P.2    Lengacher, S.3    Celio, M.4    Grau, G.E.5    Glauser, M.P.6    Heumann, D.7
  • 13
    • 78650294475 scopus 로고    scopus 로고
    • Effect of the antimicrobial decapeptide KSL on the growth of oral pathogens and Streptococcus mutans biofilm
    • PID: 20956070
    • Liu Y, Wang L, Zhou X, Hu S, Zhang S, Wu H (2011) Effect of the antimicrobial decapeptide KSL on the growth of oral pathogens and Streptococcus mutans biofilm. Int J Antimicrob Agents 37:33–38
    • (2011) Int J Antimicrob Agents , vol.37 , pp. 33-38
    • Liu, Y.1    Wang, L.2    Zhou, X.3    Hu, S.4    Zhang, S.5    Wu, H.6
  • 14
    • 0021280786 scopus 로고
    • Growth-inhibitory and bactericidal effects of human parotid salivary histidine-rich polypeptides on Streptococcus mutans
    • PID: 6724693, COI: 1:CAS:528:DyaL2cXkt1WqsLk%3D
    • MacKay BJ, Denepitiya L, Iacono VJ, Krost SB, Pollock JJ (1984) Growth-inhibitory and bactericidal effects of human parotid salivary histidine-rich polypeptides on Streptococcus mutans. Infect Immun 44:695–701
    • (1984) Infect Immun , vol.44 , pp. 695-701
    • MacKay, B.J.1    Denepitiya, L.2    Iacono, V.J.3    Krost, S.B.4    Pollock, J.J.5
  • 15
    • 75649097134 scopus 로고    scopus 로고
    • Intrinsic amino acid side-chain hydrophilicity/hydrophobicity coefficients determined by reversed-phase high-performance liquid chromatography of model peptides: comparison with other hydrophilicity/hydrophobicity scales
    • PID: 19795449, COI: 1:CAS:528:DC%2BD1MXhsVehsL3F
    • Mant CT, Kovacs JM, Kim HM, Pollock DD, Hodges RS (2009) Intrinsic amino acid side-chain hydrophilicity/hydrophobicity coefficients determined by reversed-phase high-performance liquid chromatography of model peptides: comparison with other hydrophilicity/hydrophobicity scales. Biopolymers 92:573–595
    • (2009) Biopolymers , vol.92 , pp. 573-595
    • Mant, C.T.1    Kovacs, J.M.2    Kim, H.M.3    Pollock, D.D.4    Hodges, R.S.5
  • 16
    • 25844524733 scopus 로고    scopus 로고
    • Dental plaque: biological significance of a biofilm and community life-style
    • PID: 16128825, COI: 1:CAS:528:DC%2BD2MXhtFeksL%2FM
    • Marsh PD (2005) Dental plaque: biological significance of a biofilm and community life-style. J Clin Periodontol 32:7–15
    • (2005) J Clin Periodontol , vol.32 , pp. 7-15
    • Marsh, P.D.1
  • 17
    • 0029775069 scopus 로고    scopus 로고
    • An antimicrobial peptide, magainin 2, induced rapid flip-flop of phospholipids coupled with pore formation and peptide translocation
    • PID: 8784191, COI: 1:CAS:528:DyaK28XkvVGrsr8%3D
    • Matsuzaki K, Murase O, Fujii N (1996) An antimicrobial peptide, magainin 2, induced rapid flip-flop of phospholipids coupled with pore formation and peptide translocation. Biochemistry 35:11361–11368
    • (1996) Biochemistry , vol.35 , pp. 11361-11368
    • Matsuzaki, K.1    Murase, O.2    Fujii, N.3
  • 18
    • 0025619340 scopus 로고
    • Killing of oral, gram-negative, facultative bacteria by the rabbit defensin, NP-1
    • PID: 2098709, COI: 1:STN:280:DyaK3M3nvFantg%3D%3D
    • Miyasaki KT, Bodeau AL, Selsted ME, Ganz T, Lehrer RI (1990) Killing of oral, gram-negative, facultative bacteria by the rabbit defensin, NP-1. Oral Microbiol Immunol 5:315–319
    • (1990) Oral Microbiol Immunol , vol.5 , pp. 315-319
    • Miyasaki, K.T.1    Bodeau, A.L.2    Selsted, M.E.3    Ganz, T.4    Lehrer, R.I.5
  • 19
    • 0031203411 scopus 로고    scopus 로고
    • Sensitivity of periodontal pathogens to the bactericidal activity of synthetic protegrins, antibiotic peptides derived from porcine leukocytes
    • PID: 9240381, COI: 1:CAS:528:DyaK2sXltFCit74%3D
    • Miyasaki KT, Iofel R, Lehrer RI (1997) Sensitivity of periodontal pathogens to the bactericidal activity of synthetic protegrins, antibiotic peptides derived from porcine leukocytes. J Dent Res 76:1453–1459
    • (1997) J Dent Res , vol.76 , pp. 1453-1459
    • Miyasaki, K.T.1    Iofel, R.2    Lehrer, R.I.3
  • 20
    • 84899130102 scopus 로고    scopus 로고
    • β-Boomerang antimicrobial and antiendotoxic peptides: lipidation and disulfide bond effects on activity and structure
    • PID: 24756162, COI: 1:CAS:528:DC%2BC2cXhs1GhsbzP
    • Mohanram H, Bhattacharjya S (2014) β-Boomerang antimicrobial and antiendotoxic peptides: lipidation and disulfide bond effects on activity and structure. Pharmaceuticals 7:482–501
    • (2014) Pharmaceuticals , vol.7 , pp. 482-501
    • Mohanram, H.1    Bhattacharjya, S.2
  • 21
    • 37249025605 scopus 로고    scopus 로고
    • Looking for chinks in the armor of bacterial biofilms
    • Monroe D (2007) Looking for chinks in the armor of bacterial biofilms. PLoS Biol 5:307
    • (2007) PLoS Biol , vol.5 , pp. 307
    • Monroe, D.1
  • 22
    • 0033948397 scopus 로고    scopus 로고
    • IB-367, a protegrin peptide with in vitro and in vivo activities against the microflora associated with oral mucositis
    • PID: 10858334, COI: 1:CAS:528:DC%2BD3cXksVKks7s%3D
    • Mosca DA, Hurst MA, So W, Viajar BS, Fujii CA, Falla TJ (2000) IB-367, a protegrin peptide with in vitro and in vivo activities against the microflora associated with oral mucositis. Antimicrob Agents Chemother 44:1803–1808
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 1803-1808
    • Mosca, D.A.1    Hurst, M.A.2    So, W.3    Viajar, B.S.4    Fujii, C.A.5    Falla, T.J.6
  • 23
    • 0024575208 scopus 로고
    • Role of endotoxemia in cardiovascular dysfunction and mortality. Escherichia coli and Staphylococcus aureus challenges in a canine model of human septic shock
    • PID: 2642920, COI: 1:CAS:528:DyaL1MXpt1yqtA%3D%3D
    • Natanson C, Danner RL, Elin RJ, Hosseini JM, Peart KW, Banks SM, MacVittie TJ, Walker RI, Parrillo JE (1989) Role of endotoxemia in cardiovascular dysfunction and mortality. Escherichia coli and Staphylococcus aureus challenges in a canine model of human septic shock. J Clin Investig 83:243–251
    • (1989) J Clin Investig , vol.83 , pp. 243-251
    • Natanson, C.1    Danner, R.L.2    Elin, R.J.3    Hosseini, J.M.4    Peart, K.W.5    Banks, S.M.6    MacVittie, T.J.7    Walker, R.I.8    Parrillo, J.E.9
  • 24
    • 33646756145 scopus 로고    scopus 로고
    • Brevinin1BYa: a naturally occurring peptide from frog skin with broad-spectrum antibacterial and antifungal properties
    • PID: 16713189
    • Pál T, Abraham B, Sonnevend Á, Juma P, Conlon JM (2006) Brevinin1BYa: a naturally occurring peptide from frog skin with broad-spectrum antibacterial and antifungal properties. Int J Antimicrob Agents 27:525–529
    • (2006) Int J Antimicrob Agents , vol.27 , pp. 525-529
    • Pál, T.1    Abraham, B.2    Sonnevend, Á.3    Juma, P.4    Conlon, J.M.5
  • 25
    • 33748949579 scopus 로고    scopus 로고
    • Lipopolysaccharide (endotoxin)-host defense antibacterial peptides interactions: role in bacterial resistance and prevention of sepsis
    • PID: 16854372, COI: 1:CAS:528:DC%2BD28XhtVamsr7O
    • Rosenfeld Y, Shai Y (2006) Lipopolysaccharide (endotoxin)-host defense antibacterial peptides interactions: role in bacterial resistance and prevention of sepsis. Biochim Biophys Acta 1758:1513–1522
    • (2006) Biochim Biophys Acta , vol.1758 , pp. 1513-1522
    • Rosenfeld, Y.1    Shai, Y.2
  • 26
    • 33644978944 scopus 로고    scopus 로고
    • Endotoxin (lipopolysaccharide) neutralization by innate immunity host-defense peptides. Peptide properties and plausible modes of action
    • PID: 16293630, COI: 1:CAS:528:DC%2BD28XksFOltw%3D%3D
    • Rosenfeld Y, Papo N, Shai Y (2006) Endotoxin (lipopolysaccharide) neutralization by innate immunity host-defense peptides. Peptide properties and plausible modes of action. J Biol Chem 281:1636–1643
    • (2006) J Biol Chem , vol.281 , pp. 1636-1643
    • Rosenfeld, Y.1    Papo, N.2    Shai, Y.3
  • 27
    • 0025935264 scopus 로고
    • The biophysics of peptide models of ion channels
    • PID: 1715999, COI: 1:CAS:528:DyaK3MXlsFeiur8%3D
    • Sansom MS (1991) The biophysics of peptide models of ion channels. Prog Biophys Mol Biol 55:139–235
    • (1991) Prog Biophys Mol Biol , vol.55 , pp. 139-235
    • Sansom, M.S.1
  • 28
    • 47749153335 scopus 로고    scopus 로고
    • Aggregation behavior of an ultra-pure lipopolysaccharide that stimulates TLR-4 receptors
    • PID: 18375521, COI: 1:CAS:528:DC%2BD1cXotlKhtr4%3D
    • Sasaki H, White SH (2008) Aggregation behavior of an ultra-pure lipopolysaccharide that stimulates TLR-4 receptors. Biophys J 95:986–993
    • (2008) Biophys J , vol.95 , pp. 986-993
    • Sasaki, H.1    White, S.H.2
  • 29
    • 84882236345 scopus 로고    scopus 로고
    • Peptide interactions with bacterial lipopolysaccharides
    • COI: 1:CAS:528:DC%2BC3sXhtFGrsbvF
    • Schmidtchen A, Malmsten M (2013) Peptide interactions with bacterial lipopolysaccharides. Curr Opin Colloid Interface Sci 18:381–392
    • (2013) Curr Opin Colloid Interface Sci , vol.18 , pp. 381-392
    • Schmidtchen, A.1    Malmsten, M.2
  • 30
    • 84858753893 scopus 로고    scopus 로고
    • Antimicrobial peptides and their potential application in inflammation and sepsis
    • PID: 22429567
    • Schuerholz T, Brandenburg K, Marx G (2012) Antimicrobial peptides and their potential application in inflammation and sepsis. Crit Care 16:207–214
    • (2012) Crit Care , vol.16 , pp. 207-214
    • Schuerholz, T.1    Brandenburg, K.2    Marx, G.3
  • 32
    • 0034650823 scopus 로고    scopus 로고
    • Cutting edge: cationic antimicrobial peptides block the binding of lipopolysaccharide (LPS) to LPS binding protein
    • PID: 10623792, COI: 1:CAS:528:DC%2BD3cXlt1Chtg%3D%3D
    • Scott MG, Vreugdenhil AC, Buurman WA, Hancock RE, Gold MR (2000) Cutting edge: cationic antimicrobial peptides block the binding of lipopolysaccharide (LPS) to LPS binding protein. J Immunol 164:549–553
    • (2000) J Immunol , vol.164 , pp. 549-553
    • Scott, M.G.1    Vreugdenhil, A.C.2    Buurman, W.A.3    Hancock, R.E.4    Gold, M.R.5
  • 33
    • 0032717886 scopus 로고    scopus 로고
    • Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides
    • PID: 10590302, COI: 1:CAS:528:DyaK1MXnslymu78%3D
    • Shai Y (1999) Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides. Biochim Biophys Acta 1462:55–70
    • (1999) Biochim Biophys Acta , vol.1462 , pp. 55-70
    • Shai, Y.1
  • 34
    • 65949110363 scopus 로고    scopus 로고
    • Molecular cloning of cDNAs encoding antimicrobial peptide precursors from the skin of the Chinese brown frog Rana chensinensis
    • PID: 19341344, COI: 1:CAS:528:DC%2BD1MXhtlehs7fN
    • Shang DJ, Yu F, Li J, Zheng J, Zhang L, Li Y (2009) Molecular cloning of cDNAs encoding antimicrobial peptide precursors from the skin of the Chinese brown frog Rana chensinensis. Zoolog Sci 26:220–226
    • (2009) Zoolog Sci , vol.26 , pp. 220-226
    • Shang, D.J.1    Yu, F.2    Li, J.3    Zheng, J.4    Zhang, L.5    Li, Y.6
  • 35
    • 84862805298 scopus 로고    scopus 로고
    • Design of potent, non-toxic antimicrobial agents based upon the structure of the frog skin peptide, temporin-1CEb from Chinese brown frog, Rana chensinensis
    • PID: 22348663, COI: 1:CAS:528:DC%2BC38Xlslagu70%3D
    • Shang DJ, Li X, Sun Y, Wang C, Sun L, Wei S (2012a) Design of potent, non-toxic antimicrobial agents based upon the structure of the frog skin peptide, temporin-1CEb from Chinese brown frog, Rana chensinensis. Chem Biol Drug Des 79:653–662
    • (2012) Chem Biol Drug Des , vol.79 , pp. 653-662
    • Shang, D.J.1    Li, X.2    Sun, Y.3    Wang, C.4    Sun, L.5    Wei, S.6
  • 36
    • 84871069372 scopus 로고    scopus 로고
    • Membrane interaction and antibacterial properties of chensinin-1, an antimicrobial peptide with atypical structural features from the skin of Rana chensinensis
    • PID: 22581068, COI: 1:CAS:528:DC%2BC38Xhs1ynsbzO
    • Shang DJ, Sun Y, Wang C, Wei S, Ma L, Sun L (2012b) Membrane interaction and antibacterial properties of chensinin-1, an antimicrobial peptide with atypical structural features from the skin of Rana chensinensis. Appl Microbiol Biotechnol 96:1551–1560
    • (2012) Appl Microbiol Biotechnol , vol.96 , pp. 1551-1560
    • Shang, D.J.1    Sun, Y.2    Wang, C.3    Wei, S.4    Ma, L.5    Sun, L.6
  • 37
    • 59749090689 scopus 로고    scopus 로고
    • Evaluation of the antimicrobial, antioxidant, and anti-inflammatory activities of hydroxychavicol for its potential use as an oral care agent
    • PID: 18573934, COI: 1:CAS:528:DC%2BD1MXhs1KksLs%3D
    • Sharma S, Khan IA, Ali I, Ali F, Kumar M, Kumar A (2009) Evaluation of the antimicrobial, antioxidant, and anti-inflammatory activities of hydroxychavicol for its potential use as an oral care agent. Antimicrob Agents Chemother 53:216–222
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 216-222
    • Sharma, S.1    Khan, I.A.2    Ali, I.3    Ali, F.4    Kumar, M.5    Kumar, A.6
  • 38
    • 0033532629 scopus 로고    scopus 로고
    • MD-2, a molecule that confers lipopolysaccharide responsiveness on toll-like receptor 4
    • PID: 10359581, COI: 1:CAS:528:DyaK1MXjvVSnu78%3D
    • Shimazu R, Akashi S, Ogata H, Nagai Y, Fukudome K, Miyake K, Kimoto M (1999) MD-2, a molecule that confers lipopolysaccharide responsiveness on toll-like receptor 4. J Exp Med 189(11):1777–1782
    • (1999) J Exp Med , vol.189 , Issue.11 , pp. 1777-1782
    • Shimazu, R.1    Akashi, S.2    Ogata, H.3    Nagai, Y.4    Fukudome, K.5    Miyake, K.6    Kimoto, M.7
  • 40
    • 0035859467 scopus 로고    scopus 로고
    • Antibiotic resistance of bacteria in biofilms
    • PID: 11463434, COI: 1:CAS:528:DC%2BD3MXlt1Shsbs%3D
    • Stewart PS, Costerton JW (2001) Antibiotic resistance of bacteria in biofilms. Lancet 358:135–138
    • (2001) Lancet , vol.358 , pp. 135-138
    • Stewart, P.S.1    Costerton, J.W.2
  • 41
    • 33749170651 scopus 로고    scopus 로고
    • Effect of MUC7 peptides on the growth of bacteria and on Streptococcus mutans biofilm
    • PID: 16595638, COI: 1:CAS:528:DC%2BD28XmsFykt7w%3D
    • Wei GX, Campagna AN, Bobek LA (2006) Effect of MUC7 peptides on the growth of bacteria and on Streptococcus mutans biofilm. J Antimicrob Chemother 57:1100–1109
    • (2006) J Antimicrob Chemother , vol.57 , pp. 1100-1109
    • Wei, G.X.1    Campagna, A.N.2    Bobek, L.A.3
  • 42
    • 84862830535 scopus 로고    scopus 로고
    • Effect of a novel antimicrobial peptide chrysophsin-1 on oral pathogens and Streptococcus mutans biofilms
    • Wei W, Rui T, Tong ZC, Ding YL, Rong K, Zhai SF, Liu J, Nia LX (2012) Effect of a novel antimicrobial peptide chrysophsin-1 on oral pathogens and Streptococcus mutans biofilms. Peptides 33:212–219
    • (2012) Peptides , vol.33 , pp. 212-219
    • Wei, W.1    Rui, T.2    Tong, Z.C.3    Ding, Y.L.4    Rong, K.5    Zhai, S.F.6    Liu, J.7    Nia, L.X.8
  • 43
    • 0029882221 scopus 로고    scopus 로고
    • Susceptibility of oral bacterial biofilms to antimicrobial agents
    • PID: 8642580, COI: 1:CAS:528:DyaK28Xit1yntLs%3D
    • Wilson M (1996) Susceptibility of oral bacterial biofilms to antimicrobial agents. J Med Microbiol 44:79–87
    • (1996) J Med Microbiol , vol.44 , pp. 79-87
    • Wilson, M.1
  • 44
    • 0025166114 scopus 로고
    • CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein
    • PID: 1698311, COI: 1:CAS:528:DyaK3MXksV2q
    • Wright SD, Ramos RA, Tobias PS, Ulevitch RJ, Mathison JC (1990) CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 249:1431–1433
    • (1990) Science , vol.249 , pp. 1431-1433
    • Wright, S.D.1    Ramos, R.A.2    Tobias, P.S.3    Ulevitch, R.J.4    Mathison, J.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.