Activity of an antimicrobial peptide mimetic against planktonic and biofilm cultures of oral pathogens

Antimicrobial Agents and Chemotherapy

Volumn 51, Issue 11, 2007, Pages 4125-4132

  Beckloff, Nicholas ^a   Laube, Danielle ^a   Castro, Tammy ^a,e   Furgang, David ^a   Park, Steven ^b   Perlin, David ^b   Clements, Dylan ^c   Tang, Haizhong ^c   Scott, Richard W ^c   Tew, Gregory N ^d   Diamond, Gill ^a  

^a RUTGERS SCHOOL OF DENTAL MEDICINE   (United States)

^b PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

^c PolyMedix Inc   (United States)

^d UNIVERSITY OF MASSACHUSETTS   (United States)

^e BLOOMFIELD COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 PHENYLENEETHYNYLENE DERIVATIVE; AMPHOPHILE; BACTERIUM LIPOPOLYSACCHARIDE; MAGAININ; POLYPEPTIDE ANTIBIOTIC AGENT; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GROWTH; BACTERIUM CULTURE; BIOFILM; CANDIDA; CANDIDA ALBICANS; CANDIDA DUBLINIENSIS; CANDIDA GLABRATA; CANDIDA KRUSEI; CANDIDA PARAPSILOSIS; CANDIDA TROPICALIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DENTAL CARIES; DRUG DNA BINDING; DRUG EFFICACY; MOUTH FLORA; NONHUMAN; PLANKTON; PORPHYROMONAS GINGIVALIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STREPTOCOCCUS MUTANS; STRUCTURE ACTIVITY RELATION; TOOTH;

ACTINOMYCES VISCOSUS; ALKYNES; ANTI-INFECTIVE AGENTS; BACTERIA; BACTERIAL PROTEINS; BIOFILMS; CANDIDA; DENTAL CARIES; DNA; ESCHERICHIA COLI; HUMANS; KINETICS; LIPOPOLYSACCHARIDES; MAGAININS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; MOUTH; PEPTIDES; PHENETHYLAMINES; PROTEIN BINDING; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS MUTANS;

EID: 35848962760     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00208-07     Document Type: Article

References (36)

1. Brogden, K. A. 2005. Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? Nat. Rev. Microbiol. 3:238-250.
2. Burne, R. A. 1998. Oral streptococci. . .products of their environment. J. Dent. Res. 77:445-452.
3. Chen, X., H. Tang, M. A. Even, J. Wang, G. N. Tew, and Z. Chen. 2006. Observing a molecular knife at work. J. Am. Chem. Soc. 128:2711-2714.
4. Cole, A. M., R. O. Darouiche, D. Legarda, N. Connell, and G. Diamond. 2000. Characterization of a fish antimicrobial peptide: gene expression, subcellular localization, and spectrum of activity. Antimicrob. Agents Chemother. 44:2039-2045.
5. Cole, A. M., P. Weis, and G. Diamond. 1997. Isolation and characterization of pleurocidin, an antimicrobial peptide in the skin secretions of winter flounder. J. Biol. Chem. 272:12008-12013.
6. Edgerton, M., and S. E. Koshlukova. 2000. Salivary histatin 5 and its similarities to the other antimicrobial proteins in human saliva. Adv. Dent. Res. 14:16-21.
7. Edwards, K. J., T. C. Jenkins, and S. Neidle. 1992. Crystal structure of a pentamidine-oligonucleotide complex: implications for DNA-binding properties. Biochemistry 31:7104-7109.
8. Ferguson, A. D., V. Braun, H. P. Fiedler, J. W. Coulton, K. Diederichs, and W. Welte. 2000. Crystal structure of the antibiotic albomycin in complex with the outer membrane transporter FhuA. Protein Sci. 9:956-963.
9. Gasteiger, J., and J. Marsili. 1980. Iterative partial equalization of orbital electronegativity - a rapid access to atomic charges. Tetrahedron 36:3219-3228.
10. Guex, N., and M. C. Peitsch. 1997. SWISS-MODEL and the Swiss-Pdb-Viewer: an environment for comparative protein modeling. Electrophoresis 18:2714-2723.
11. Hancock, R. E., and G. Diamond. 2000. The role of cationic antimicrobial peptides in innate host defences. Trends Microbiol. 8:402-410.
12. Hsu, C. H., C. Chen, M. L. Jou, A. Y. Lee, Y. C. Lin, Y. P. Yu, W. T. Huang, and S. H. Wu. 2005. Structural and DNA-binding studies on the bovine antimicrobial peptide, indolicidin: evidence for multiple conformations involved in binding to membranes and DNA. Nucleic Acids Res. 33:4053-4064.
13. Kerrigan, J. E., D. S. Pilch, A. L. Ruchelman, N. Zhou, A. Liu, L. Liu, and E. J. LaVoie. 2003. 5H-8,9-Dimethoxy-5-(2-N,N-dimethylaminoethyl)dibenzo[c,h][1,6] naphthyridin-6-ones and related compounds as TOP1-targeting agents: influence of structure on the ternary cleavable complex formation. Bioorg. Med. Chem. Lett. 13:3395-3399.
14. Kim, S. S., S. Kim, E. Kim, B. Hyun, K. K. Kim, and B. J. Lee. 2003. Synergistic inhibitory effect of cationic peptides and antimicrobial agents on the growth of oral streptococci. Caries Res. 37:425-430.
15. Kuyyakanond, T., and L. B. Quesnel. 1992. The mechanism of action of chlorhexidine. FEMS Microbiol. Lett. 79:211-215.
16. Leontiadou, H., A. E. Mark, and S. J. Marrink. 2006. Antimicrobial peptides in action. J. Am. Chem. Soc. 128:12156-12161.
17. Lewis, K. 2001. Riddle of biofilm resistance. Antimicrob. Agents Chemother. 45:999-1007.
18. Mah, T. F., and G. A. O'Toole. 2001. Mechanisms of biofilm resistance to antimicrobial agents. Trends Microbiol. 9:34-39.
19. Merritt, J. H., D. Kadouri, and G. A. O'Toole. 2005. Growing and analyzing static biofilms, p. 1-17. In R. Coico, T. Kowalik, J. Quarles, B. Stevenson, and R. Taylor (ed.), Current protocols in microbiology, vol. 1. John Wiley & Sons, Hoboken, NJ.
20. Miller, M. A. 2002. Chemical database techniques in drug discovery. Nat. Rev. Drug Discov. 1:220-227.
21. Morris, G. M., D. S. Goodsell, R. S. Halliday, R. Huey, W. E. Hart, R. K. Belew, and A. J. Olson. 1998. Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function. J. Comp. Chem. 19:1639-1662.
22. Nagaoka, I., S. Hirota, F. Niyonsaba, M. Hirata, Y. Adachi, H. Tamura, and D. Heumann. 2001. Cathelicidin family of antibacterial peptides CAP18 and CAP11 inhibit the expression of TNF-alpha by blocking the binding of LPS to CD14(+) cells. J. Immunol. 167:3329-3338.
23. National Committee for Clinical Laboratory Standards. 2002. Reference method for broth dilution antifungal susceptibility testing of yeasts Approved standard M27-A2. National Committee for Clinical Laboratory Standards, Wayne, PA.
24. Pazgier, M., D. M. Hoover, D. Yang, W. Lu, and J. Lubkowski. 2006. Human beta-defensins. Cell. Mol. Life Sci. 63:1294-1313.
25. Rennie, J., L. Arnt, H. Tang, K. Nusslein, and G. N. Tew. 2005. Simple oligomers as antimicrobial peptide mimics. J. Ind. Microbiol. Biotechnol. 32:296-300.
26. Rosenfeld, Y., N. Papo, and Y. Shai. 2006. Endotoxin (lipopolysaccharide) neutralization by innate immunity host-defense peptides. Peptide properties and plausible modes of action. J. Biol. Chem. 281:1636-1643.
27. Sheridan, R. P. 2002. The most common chemical replacements in drug-like compounds. J. Chem. Inf. Comput. Sci. 42:103-108.
28. Steinberg, D. A., and R. I. Lehrer. 1997. Designer assays for antimicrobial peptides. Disputing the "one-size-fits-all" theory. Methods Mol. Biol. 78:169-186.
29. Tew, G. N., D. Clements, H. Tang, L. Arnt, and R. W. Scott. 2006. Antimicrobial activity of an abiotic host defense peptide mimic. Biochim. Biophys. Acta 1758:1387-1392.
30. Tew, G. N., D. Liu, B. Chen, R. J. Doerksen, J. Kaplan, P. J. Carroll, M. L. Klein, and W. F. DeGrado. 2002. De novo design of biomimetic antimicrobial polymers. Proc. Natl. Acad. Sci. USA 99:5110-5114.
31. Velliyagounder, K., J. B. Kaplan, D. Furgang, D. Legarda, G. Diamond, R. E. Parkin, and D. H. Fine. 2003. One of two human lactoferrin variants exhibits increased antibacterial and transcriptional activation activities and is associated with localized juvenile periodontitis. Infect. Immun. 71:6141-6147.
32. Vorland, L. H., H. Ulvatne, O. Rekdal, and J. S. Svendsen. 1999. Initial binding sites of antimicrobial peptides in Staphylococcus aureus and Escherichia coli. Scand. J. Infect. Dis. 31:467-473.
33. Wei, G. X., A. N. Campagna, and L. A. Bobek. 2006. Effect of MUC7 peptides on the growth of bacteria and on Streptococcus mutans biofilm. J. Antimicrob Chemother. 57:1100-1109.
34. Yamada, T., S. Takahashi-Abbe, and K. Abbe. 1985. Effects of oxygen on pyruvate formate-lyase in situ and sugar metabolism of Streptococcus mutans and Streptococcus sanguis. Infect. Immun. 47:129-134.
35. Zasloff, M. 2002. Antimicrobial peptides of multicellular organisms. Nature 415:389-395.
36. Zasloff, M. 1987. Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor. Proc. Natl. Acad. Sci. USA 84:5449-5453.