메뉴 건너뛰기




Volumn 5, Issue DEC, 2014, Pages

O-GlcNAcylation links ChREBP and FXR to glucose-sensing

Author keywords

ChREBP; FXR; Glucose sensing; Liver metabolism; O GlcNAcylation

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR; CARBOHYDRATE RESPONSIVE ELEMENT BINDING PROTEIN; CELL NUCLEUS RECEPTOR; CHENODEOXYCHOLIC ACID; FARNESOID X RECEPTOR; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; N ACETYLGLUCOSAMINE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); RETINOID X RECEPTOR; SUMO PROTEIN; UNCLASSIFIED DRUG;

EID: 84920162021     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2014.00230     Document Type: Short Survey
Times cited : (30)

References (40)
  • 1
    • 0035979214 scopus 로고    scopus 로고
    • A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver
    • Epub 2001/07/27 [pii], 161284298, PubMed PMID: 11470916; PubMed Central PMCID: PMC55382.
    • Yamashita H, Takenoshita M, Sakurai M, Bruick RK, Henzel WJ, Shillinglaw W, et al. A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver. Proc Natl Acad Sci U S A (2001) 98(16):9116-21. Epub 2001/07/27. doi: 10.1073/pnas.161284298 161284298 [pii]. PubMed PMID: 11470916; PubMed Central PMCID: PMC55382.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.16 , pp. 9116-9121
    • Yamashita, H.1    Takenoshita, M.2    Sakurai, M.3    Bruick, R.K.4    Henzel, W.J.5    Shillinglaw, W.6
  • 2
    • 0037040185 scopus 로고    scopus 로고
    • Mechanism for fatty acid "sparing" effect on glucose-induced transcription: regulation of carbohydrate-responsive element-binding protein by AMP-activated protein kinase
    • Epub 2001/11/29 [pii], M107895200 PubMed PMID: 11724780.
    • Kawaguchi T, Osatomi K, Yamashita H, Kabashima T, Uyeda K. Mechanism for fatty acid "sparing" effect on glucose-induced transcription: regulation of carbohydrate-responsive element-binding protein by AMP-activated protein kinase. J Biol Chem (2002) 277(6):3829-35. Epub 2001/11/29. doi: 10.1074/jbc. M107895200 M107895200 [pii]. PubMed PMID: 11724780.
    • (2002) J Biol Chem , vol.277 , Issue.6 , pp. 3829-3835
    • Kawaguchi, T.1    Osatomi, K.2    Yamashita, H.3    Kabashima, T.4    Uyeda, K.5
  • 3
    • 2442489891 scopus 로고    scopus 로고
    • Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression
    • PubMed PMID: 14985368, M312475200 Epub 2004/02/27
    • Dentin R, Pegorier JP, Benhamed F, Foufelle F, Ferre P, Fauveau V, et al. Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression. J Biol Chem (2004) 279(19):20314-26. Epub 2004/02/27. doi: 10.1074/jbc. M312475200 M312475200 [pii]. PubMed PMID: 14985368.
    • (2004) J Biol Chem , vol.279 , Issue.19 , pp. 20314-20326
    • Dentin, R.1    Pegorier, J.P.2    Benhamed, F.3    Foufelle, F.4    Ferre, P.5    Fauveau, V.6
  • 4
    • 0035923516 scopus 로고    scopus 로고
    • Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein
    • PubMed PMID: 11698644; PubMed Central PMCID: PMC61106, Epub 2001/11/08 [pii] 231370798
    • Kawaguchi T, Takenoshita M, Kabashima T, Uyeda K. Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein. Proc Natl Acad Sci U S A (2001) 98(24):13710-5. Epub 2001/11/08. doi: 10.1073/pnas.231370798 231370798 [pii]. PubMed PMID: 11698644; PubMed Central PMCID: PMC61106.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.24 , pp. 13710-13715
    • Kawaguchi, T.1    Takenoshita, M.2    Kabashima, T.3    Uyeda, K.4
  • 5
    • 78649855297 scopus 로고    scopus 로고
    • Salt inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice
    • PubMed PMID: 21084751; PubMed Central PMCID: PMC2993582, Epub 2010/11/19. 41624
    • Bricambert J, Miranda J, Benhamed F, Girard J, Postic C, Dentin R. Salt inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice. J Clin Invest (2010) 120(12):4316-31. Epub 2010/11/19. doi: 41624 [pii] 10.1172/JCI41624. PubMed PMID: 21084751; PubMed Central PMCID: PMC2993582.
    • (2010) J Clin Invest , vol.120 , Issue.12 , pp. 4316-4331
    • Bricambert, J.1    Miranda, J.2    Benhamed, F.3    Girard, J.4    Postic, C.5    Dentin, R.6
  • 6
    • 79959473762 scopus 로고    scopus 로고
    • O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver
    • Epub 2011/04/08. db10-0452, PubMed PMID: 21471514; PubMed Central PMCID: PMC3292313
    • Guinez C, Filhoulaud G, Rayah-Benhamed F, Marmier S, Dubuquoy C, Dentin R, et al. O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver. Diabetes (2011) 60(5):1399-413. Epub 2011/04/08. doi: db10-0452 [pii] 10.2337/db10-0452. PubMed PMID: 21471514; PubMed Central PMCID: PMC3292313.
    • (2011) Diabetes , vol.60 , Issue.5 , pp. 1399-1413
    • Guinez, C.1    Filhoulaud, G.2    Rayah-Benhamed, F.3    Marmier, S.4    Dubuquoy, C.5    Dentin, R.6
  • 7
    • 84867290287 scopus 로고    scopus 로고
    • Hepatic FoxO1 integrates glucose utilization and lipid synthesis through regulation of Chrebp O-glycosylation
    • Epub 2012/10/12 PONE-D-12-18280, PubMed PMID: 23056614; PubMed Central PMCID: PMC3466224.
    • Ido-Kitamura Y, Sasaki T, Kobayashi M, Kim HJ, Lee YS, Kikuchi O, et al. Hepatic FoxO1 integrates glucose utilization and lipid synthesis through regulation of Chrebp O-glycosylation. PLoS One (2012) 7(10):e47231. Epub 2012/10/12. doi: 10.1371/journal.pone.0047231 PONE-D-12-18280 [pii]. PubMed PMID: 23056614; PubMed Central PMCID: PMC3466224.
    • (2012) PLoS One , vol.7 , Issue.10
    • Ido-Kitamura, Y.1    Sasaki, T.2    Kobayashi, M.3    Kim, H.J.4    Lee, Y.S.5    Kikuchi, O.6
  • 8
    • 79959381299 scopus 로고    scopus 로고
    • Cross talk between O GlcNAcylation and phosphorylation: roles in signaling, transcription, and chronic disease
    • Epub 2011/03/12, PubMed PMID: 21391816
    • Hart GW, Slawson C, Ramirez-Correa G, Lagerlof O. Cross talk between O GlcNAcylation and phosphorylation: roles in signaling, transcription, and chronic disease. Annu Rev Biochem (2011) 80:825-58. Epub 2011/03/12. doi: 10.1146/annurev-biochem-060608-102511. PubMed PMID: 21391816.
    • (2011) Annu Rev Biochem , vol.80 , pp. 825-858
    • Hart, G.W.1    Slawson, C.2    Ramirez-Correa, G.3    Lagerlof, O.4
  • 9
    • 84899475842 scopus 로고    scopus 로고
    • Glucose sensing O-GlcNAcylation pathway regulates the nuclear bile acid receptor farnesoid X receptor (FXR)
    • Epub 2013/09/17, PubMed PMID: 24037988.
    • Berrabah W, Aumercier P, Gheeraert C, Dehondt H, Bouchaert E, Alexandre J, et al. Glucose sensing O-GlcNAcylation pathway regulates the nuclear bile acid receptor farnesoid X receptor (FXR). Hepatology (2014) 59(5):2022-33. Epub 2013/09/17. doi: 10.1002/hep.26710. PubMed PMID: 24037988.
    • (2014) Hepatology , vol.59 , Issue.5 , pp. 2022-2033
    • Berrabah, W.1    Aumercier, P.2    Gheeraert, C.3    Dehondt, H.4    Bouchaert, E.5    Alexandre, J.6
  • 10
    • 58249110568 scopus 로고    scopus 로고
    • Role of bile acids and bile acid receptors in metabolic regulation
    • Epub 2009/01/08 89/1/147, PubMed PMID: 19126757.
    • Lefebvre P, Cariou B, Lien F, Kuipers F, Staels B. Role of bile acids and bile acid receptors in metabolic regulation. Physiol Rev (2009) 89(1):147-91. Epub 2009/01/08. doi: 89/1/147 [pii] 10.1152/physrev.00010.2008. PubMed PMID: 19126757.
    • (2009) Physiol Rev , vol.89 , Issue.1 , pp. 147-191
    • Lefebvre, P.1    Cariou, B.2    Lien, F.3    Kuipers, F.4    Staels, B.5
  • 11
    • 84878972563 scopus 로고    scopus 로고
    • Farnesoid X receptor inhibits the transcriptional activity of carbohydrate response element binding protein in human hepatocytes
    • Epub 2013/03/2701004-12 PubMed PMID: 23530060; PubMed Central PMCID: PMC3648076.
    • Caron S, Huaman Samanez C, Dehondt H, Ploton M, Briand O, Lien F, et al. Farnesoid X receptor inhibits the transcriptional activity of carbohydrate response element binding protein in human hepatocytes. Mol Cell Biol (2013) 33(11):2202-11. Epub 2013/03/27. doi: MCB.01004-12 [pii] 10.1128/MCB.01004-12. PubMed PMID: 23530060; PubMed Central PMCID: PMC3648076.
    • (2013) Mol Cell Biol , vol.33 , Issue.11 , pp. 2202-2211
    • Caron, S.1    Huaman Samanez, C.2    Dehondt, H.3    Ploton, M.4    Briand, O.5    Lien, F.6
  • 12
    • 2442435802 scopus 로고    scopus 로고
    • Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis
    • Epub 2004/05/01, 0401516101 PubMed PMID: 15118080; PubMed Central PMCID: PMC409910.
    • Iizuka K, Bruick RK, Liang G, Horton JD, Uyeda K. Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis. Proc Natl Acad Sci U S A (2004) 101(19):7281-6. Epub 2004/05/01. doi: 10.1073/pnas.0401516101 0401516101 [pii]. PubMed PMID: 15118080; PubMed Central PMCID: PMC409910.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.19 , pp. 7281-7286
    • Iizuka, K.1    Bruick, R.K.2    Liang, G.3    Horton, J.D.4    Uyeda, K.5
  • 13
    • 84859921736 scopus 로고    scopus 로고
    • A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism
    • Epub 2012/04/03 nature10986 PubMed PMID: 22466288; PubMed Central PMCID: PMC3341994.
    • Herman MA, Peroni OD, Villoria J, Schon MR, Abumrad NA, Bluher M, et al. A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism. Nature (2012) 484(7394):333-8. Epub 2012/04/03. doi: nature10986 [pii] 10.1038/nature10986. PubMed PMID: 22466288; PubMed Central PMCID: PMC3341994.
    • (2012) Nature , vol.484 , Issue.7394 , pp. 333-338
    • Herman, M.A.1    Peroni, O.D.2    Villoria, J.3    Schon, M.R.4    Abumrad, N.A.5    Bluher, M.6
  • 14
    • 77449122260 scopus 로고    scopus 로고
    • Carbohydrate-responsive element-binding protein (ChREBP) is a negative regulator of ARNT/HIF-1beta gene expression in pancreatic islet beta-cells
    • Epub 2009/10/17 db08-0868 [PubMed PMID: 19833882; PubMed Central PMCID: PMC2797916.
    • Noordeen NA, Khera TK, Sun G, Longbottom ER, Pullen TJ, da Silva Xavier G, et al. Carbohydrate-responsive element-binding protein (ChREBP) is a negative regulator of ARNT/HIF-1beta gene expression in pancreatic islet beta-cells. Diabetes (2010) 59(1):153-60. Epub 2009/10/17. doi: db08-0868 [pii] 10.2337/db08-0868. PubMed PMID: 19833882; PubMed Central PMCID: PMC2797916.
    • (2010) Diabetes , vol.59 , Issue.1 , pp. 153-160
    • Noordeen, N.A.1    Khera, T.K.2    Sun, G.3    Longbottom, E.R.4    Pullen, T.J.5    da Silva Xavier, G.6
  • 15
    • 79960642153 scopus 로고    scopus 로고
    • Integrated expression profiling and genome-wide analysis of ChREBP targets reveals the dual role for ChREBP in glucose-regulated gene expression
    • Epub 2011/08/04 PubMed PMID: 21811631; PubMed Central PMCID: PMC3141076.
    • Jeong YS, Kim D, Lee YS, Kim HJ, Han JY, Im SS, et al. Integrated expression profiling and genome-wide analysis of ChREBP targets reveals the dual role for ChREBP in glucose-regulated gene expression. PLoS One (2011) 6(7):e22544. Epub 2011/08/04. doi: 10.1371/journal.pone.0022544 PONE-D-10-05011 [pii]. PubMed PMID: 21811631; PubMed Central PMCID: PMC3141076.
    • (2011) PLoS One , vol.6 , Issue.7
    • Jeong, Y.S.1    Kim, D.2    Lee, Y.S.3    Kim, H.J.4    Han, J.Y.5    Im, S.S.6
  • 16
    • 0035877604 scopus 로고    scopus 로고
    • Involvement of a unique carbohydrate-responsive factor in the glucose regulation of rat liver fatty-acid synthase gene transcription
    • Epub 2001/03/30 M100461200 PubMed PMID: 11279238
    • Rufo C, Teran-Garcia M, Nakamura MT, Koo SH, Towle HC, Clarke SD. Involvement of a unique carbohydrate-responsive factor in the glucose regulation of rat liver fatty-acid synthase gene transcription. J Biol Chem (2001) 276(24):21969-75. Epub 2001/03/30. doi: 10.1074/jbc. M100461200 M100461200 [pii]. PubMed PMID: 11279238.
    • (2001) J Biol Chem , vol.276 , Issue.24 , pp. 21969-21975
    • Rufo, C.1    Teran-Garcia, M.2    Nakamura, M.T.3    Koo, S.H.4    Towle, H.C.5    Clarke, S.D.6
  • 17
    • 33749407193 scopus 로고    scopus 로고
    • ChREBP*Mlx is the principal mediator of glucose-induced gene expression in the liver
    • Epub 2006/08/04 M601576200 PubMed PMID: 16885160.
    • Ma L, Robinson LN, Towle HC. ChREBP*Mlx is the principal mediator of glucose-induced gene expression in the liver. J Biol Chem (2006) 281(39):28721-30. Epub 2006/08/04. doi: M601576200 [pii] 10.1074/jbc. M601576200. PubMed PMID: 16885160.
    • (2006) J Biol Chem , vol.281 , Issue.39 , pp. 28721-28730
    • Ma, L.1    Robinson, L.N.2    Towle, H.C.3
  • 18
    • 84876998618 scopus 로고    scopus 로고
    • Novel insights into ChREBP regulation and function
    • Epub 2013/04/20 PubMed PMID: 23597489.
    • Filhoulaud G, Guilmeau S, Dentin R, Girard J, Postic C. Novel insights into ChREBP regulation and function. Trends Endocrinol Metab (2013) 24(5):257-68. Epub 2013/04/20. doi: S1043-2760(13)00015-5 [pii] 10.1016/j.tem.2013.01.003. PubMed PMID: 23597489.
    • (2013) Trends Endocrinol Metab , vol.24 , Issue.5 , pp. 257-268
    • Filhoulaud, G.1    Guilmeau, S.2    Dentin, R.3    Girard, J.4    Postic, C.5
  • 19
    • 0038561165 scopus 로고    scopus 로고
    • Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver
    • Epub 2003/04/10, 0730817100 PubMed PMID: 12684532; PubMed Central PMCID: PMC154306.
    • Kabashima T, Kawaguchi T, Wadzinski BE, Uyeda K. Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver. Proc Natl Acad Sci U S A (2003) 100(9):5107-12. Epub 2003/04/10. doi: 10.1073/pnas.0730817100 0730817100 [pii]. PubMed PMID: 12684532; PubMed Central PMCID: PMC154306.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.9 , pp. 5107-5112
    • Kabashima, T.1    Kawaguchi, T.2    Wadzinski, B.E.3    Uyeda, K.4
  • 20
    • 33745297834 scopus 로고    scopus 로고
    • Glucose-dependent transcriptional regulation by an evolutionarily conserved glucose-sensing module
    • Epub 2006/04/29 55/5/1179, PubMed PMID: 16644671.
    • Li MV, Chang B, Imamura M, Poungvarin N, Chan L. Glucose-dependent transcriptional regulation by an evolutionarily conserved glucose-sensing module. Diabetes (2006) 55(5):1179-89. Epub 2006/04/29. doi: 55/5/1179 [pii]. PubMed PMID: 16644671.
    • (2006) Diabetes , vol.55 , Issue.5 , pp. 1179-1189
    • Li, M.V.1    Chang, B.2    Imamura, M.3    Poungvarin, N.4    Chan, L.5
  • 21
    • 46349101190 scopus 로고    scopus 로고
    • Glucose-mediated transactivation of carbohydrate response element-binding protein requires cooperative actions from Mondo conserved regions and essential trans-acting factor 14-3-3
    • Epub 2008/04/262007-0560, PubMed PMID: 18436566; PubMed Central PMCID: PMC2453601.
    • Li MV, Chen W, Poungvarin N, Imamura M, Chan L. Glucose-mediated transactivation of carbohydrate response element-binding protein requires cooperative actions from Mondo conserved regions and essential trans-acting factor 14-3-3. Mol Endocrinol (2008) 22(7):1658-72. Epub 2008/04/26. doi: me.2007-0560 [pii] 10.1210/me.2007-0560. PubMed PMID: 18436566; PubMed Central PMCID: PMC2453601.
    • (2008) Mol Endocrinol , vol.22 , Issue.7 , pp. 1658-1672
    • Li, M.V.1    Chen, W.2    Poungvarin, N.3    Imamura, M.4    Chan, L.5
  • 22
    • 84859593599 scopus 로고    scopus 로고
    • A novel N-terminal domain may dictate the glucose response of Mondo proteins
    • Epub 2012/04/17 PubMed PMID: 22506051; PONE-D-11-16001 PubMed Central PMCID: PMC3323566.
    • McFerrin LG, Atchley WR. A novel N-terminal domain may dictate the glucose response of Mondo proteins. PLoS One (2012) 7(4):e34803. Epub 2012/04/17. doi: 10.1371/journal.pone.0034803 PONE-D-11-16001 [pii]. PubMed PMID: 22506051; PubMed Central PMCID: PMC3323566.
    • (2012) PLoS One , vol.7 , Issue.4
    • McFerrin, L.G.1    Atchley, W.R.2
  • 23
    • 77951848682 scopus 로고    scopus 로고
    • Glucose-6-phosphate mediates activation of the carbohydrate responsive binding protein (ChREBP)
    • Epub 2010/04/13, PubMed PMID: 20382127; PubMed Central PMCID: PMC2874883.
    • Li MV, Chen W, Harmancey RN, Nuotio-Antar AM, Imamura M, Saha P, et al. Glucose-6-phosphate mediates activation of the carbohydrate responsive binding protein (ChREBP). Biochem Biophys Res Commun (2010) 395(3):395-400. Epub 2010/04/13. doi: S0006-291X(10)00690-X [pii] 10.1016/j.bbrc.2010.04.028. PubMed PMID: 20382127; PubMed Central PMCID: PMC2874883.
    • (2010) Biochem Biophys Res Commun , vol.395 , Issue.3 , pp. 395-400
    • Li, M.V.1    Chen, W.2    Harmancey, R.N.3    Nuotio-Antar, A.M.4    Imamura, M.5    Saha, P.6
  • 24
    • 83555160898 scopus 로고    scopus 로고
    • Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in liver.
    • Epub 2011/08/13. PubMed PMID: 21835137.
    • Dentin R, Tomas-Cobos L, Foufelle F, Leopold J, Girard J, Postic C, et al. Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in liver. J Hepatol (2011). Epub 2011/08/13. doi: S0168-8278(11)00613-1 [pii] 10.1016/j.jhep.2011.07.019. PubMed PMID: 21835137.
    • (2011) J Hepatol
    • Dentin, R.1    Tomas-Cobos, L.2    Foufelle, F.3    Leopold, J.4    Girard, J.5    Postic, C.6
  • 25
    • 8144229872 scopus 로고    scopus 로고
    • Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription
    • Epub 2004/10/22 0405238101, PubMed PMID: 15496471; PubMed Central PMCID: PMC524841.
    • Ishii S, Iizuka K, Miller BC, Uyeda K. Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription. Proc Natl Acad Sci U S A (2004) 101(44):15597-602. Epub 2004/10/22. doi: 0405238101 [pii] 10.1073/pnas.0405238101. PubMed PMID: 15496471; PubMed Central PMCID: PMC524841.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.44 , pp. 15597-15602
    • Ishii, S.1    Iizuka, K.2    Miller, B.C.3    Uyeda, K.4
  • 26
    • 33745896223 scopus 로고    scopus 로고
    • Deficiency of carbohydrate-activated transcription factor ChREBP prevents obesity and improves plasma glucose control in leptin-deficient (ob/ob) mice
    • Epub 2006/05/18. 00027.2006, PubMed PMID: 16705063.
    • Iizuka K, Miller B, Uyeda K. Deficiency of carbohydrate-activated transcription factor ChREBP prevents obesity and improves plasma glucose control in leptin-deficient (ob/ob) mice. Am J Physiol Endocrinol Metab (2006) 291(2):E358-64. Epub 2006/05/18. doi: 00027.2006 [pii] 10.1152/ajpendo.00027.2006. PubMed PMID: 16705063.
    • (2006) Am J Physiol Endocrinol Metab , vol.291 , Issue.2 , pp. E358-E364
    • Iizuka, K.1    Miller, B.2    Uyeda, K.3
  • 27
    • 84861809881 scopus 로고    scopus 로고
    • The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans
    • Epub 2012/05/02 41636, PubMed PMID: 22546860; PubMed Central PMCID: PMC3366390.
    • Benhamed F, Denechaud PD, Lemoine M, Robichon C, Moldes M, Bertrand-Michel J, et al. The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans. J Clin Invest (2012) 122(6):2176-94. Epub 2012/05/02. doi: 41636 [pii] 10.1172/JCI41636. PubMed PMID: 22546860; PubMed Central PMCID: PMC3366390.
    • (2012) J Clin Invest , vol.122 , Issue.6 , pp. 2176-2194
    • Benhamed, F.1    Denechaud, P.D.2    Lemoine, M.3    Robichon, C.4    Moldes, M.5    Bertrand-Michel, J.6
  • 28
    • 1842527650 scopus 로고    scopus 로고
    • Glucose regulates the expression of the farnesoid X receptor in liver.
    • Epub 2004/03/30. PubMed PMID: 15047603
    • Duran-Sandoval D, Mautino G, Martin G, Percevault F, Barbier O, Fruchart JC, et al. Glucose regulates the expression of the farnesoid X receptor in liver. Diabetes (2004) 53(4):890-8. Epub 2004/03/30. PubMed PMID: 15047603.
    • (2004) Diabetes , vol.53 , Issue.4 , pp. 890-898
    • Duran-Sandoval, D.1    Mautino, G.2    Martin, G.3    Percevault, F.4    Barbier, O.5    Fruchart, J.C.6
  • 29
    • 22544452537 scopus 로고    scopus 로고
    • The farnesoid X receptor modulates hepatic carbohydrate metabolism during the fasting-refeeding transition
    • Epub 2005/05/19 M501931200, PubMed PMID: 15899888.
    • Duran-Sandoval D, Cariou B, Percevault F, Hennuyer N, Grefhorst A, van Dijk TH, et al. The farnesoid X receptor modulates hepatic carbohydrate metabolism during the fasting-refeeding transition. J Biol Chem (2005) 280(33):29971-9. Epub 2005/05/19. doi: M501931200 [pii] 10.1074/jbc. M501931200. PubMed PMID: 15899888.
    • (2005) J Biol Chem , vol.280 , Issue.33 , pp. 29971-29979
    • Duran-Sandoval, D.1    Cariou, B.2    Percevault, F.3    Hennuyer, N.4    Grefhorst, A.5    van Dijk, T.H.6
  • 30
    • 22544474215 scopus 로고    scopus 로고
    • Transient impairment of the adaptive response to fasting in FXR deficient mice
    • Epub 2005/07/19, PubMed PMID: 16023103
    • Cariou B, van Harmelen K, Duran-Sandoval D, van Dijk T, Grefhorst A, Bouchaert E, et al. Transient impairment of the adaptive response to fasting in FXR deficient mice. FEBS Lett (2005) 579(19):4076-80. Epub 2005/07/19. doi: S0014-5793(05)00764-7 [pii] 10.1016/j.febslet.2005.06.033. PubMed PMID: 16023103.
    • (2005) FEBS Lett , vol.579 , Issue.19 , pp. 4076-4080
    • Cariou, B.1    van Harmelen, K.2    Duran-Sandoval, D.3    van Dijk, T.4    Grefhorst, A.5    Bouchaert, E.6
  • 31
    • 14244264780 scopus 로고    scopus 로고
    • Regulation of carbohydrate metabolism by the farnesoid X receptor
    • Epub 2004/11/272004-0965, PubMed PMID: 15564327.
    • Stayrook KR, Bramlett KS, Savkur RS, Ficorilli J, Cook T, Christe ME, et al. Regulation of carbohydrate metabolism by the farnesoid X receptor. Endocrinology (2005) 146(3):984-91. Epub 2004/11/27. doi: en.2004-0965 [pii] 10.1210/en.2004-0965. PubMed PMID: 15564327.
    • (2005) Endocrinology , vol.146 , Issue.3 , pp. 984-991
    • Stayrook, K.R.1    Bramlett, K.S.2    Savkur, R.S.3    Ficorilli, J.4    Cook, T.5    Christe, M.E.6
  • 32
    • 0038752647 scopus 로고    scopus 로고
    • Structural basis for bile acid binding and activation of the nuclear receptor FXR
    • Epub 2003/04/30, PubMed PMID: 12718893
    • Mi LZ, Devarakonda S, Harp JM, Han Q, Pellicciari R, Willson TM, et al. Structural basis for bile acid binding and activation of the nuclear receptor FXR. Mol Cell (2003) 11(4):1093-100. Epub 2003/04/30. doi: S1097276503001126 [pii]. PubMed PMID: 12718893.
    • (2003) Mol Cell , vol.11 , Issue.4 , pp. 1093-1100
    • Mi, L.Z.1    Devarakonda, S.2    Harp, J.M.3    Han, Q.4    Pellicciari, R.5    Willson, T.M.6
  • 33
    • 78649443736 scopus 로고    scopus 로고
    • The role of O-linked GlcNAc modification on the glucose response of ChREBP
    • Epub 2010/11/03, PubMed PMID: 21036147.
    • Sakiyama H, Fujiwara N, Noguchi T, Eguchi H, Yoshihara D, Uyeda K, et al. The role of O-linked GlcNAc modification on the glucose response of ChREBP. Biochem Biophys Res Commun (2010) 402(4):784-9. Epub 2010/11/03. doi: S0006-291X(10)02002-4 [pii] 10.1016/j.bbrc.2010.10.113. PubMed PMID: 21036147.
    • (2010) Biochem Biophys Res Commun , vol.402 , Issue.4 , pp. 784-789
    • Sakiyama, H.1    Fujiwara, N.2    Noguchi, T.3    Eguchi, H.4    Yoshihara, D.5    Uyeda, K.6
  • 34
    • 84877710429 scopus 로고    scopus 로고
    • SUMOylation of the farnesoid X receptor (FXR) regulates the expression of FXR target genes
    • Epub 2013/04/03 M112.443937, PubMed PMID: 23546875; PubMed Central PMCID: PMC3650421
    • Balasubramaniyan N, Luo Y, Sun AQ, Suchy FJ. SUMOylation of the farnesoid X receptor (FXR) regulates the expression of FXR target genes. J Biol Chem (2013) 288(19):13850-62. Epub 2013/04/03. doi: M112.443937 [pii] 10.1074/jbc. M112.443937. PubMed PMID: 23546875; PubMed Central PMCID: PMC3650421.
    • (2013) J Biol Chem , vol.288 , Issue.19 , pp. 13850-13862
    • Balasubramaniyan, N.1    Luo, Y.2    Sun, A.Q.3    Suchy, F.J.4
  • 35
    • 84894029904 scopus 로고    scopus 로고
    • Protein O-GlcNAcylation in diabetes and diabetic complications
    • Epub 2013/09/03, PubMed PMID: 23992419; PubMed Central PMCID: PMC3985334
    • Ma J, Hart GW. Protein O-GlcNAcylation in diabetes and diabetic complications. Expert Rev Proteomics (2013) 10(4):365-80. Epub 2013/09/03. doi: 10.1586/14789450.2013.820536. PubMed PMID: 23992419; PubMed Central PMCID: PMC3985334.
    • (2013) Expert Rev Proteomics , vol.10 , Issue.4 , pp. 365-380
    • Ma, J.1    Hart, G.W.2
  • 36
    • 40449128605 scopus 로고    scopus 로고
    • Hepatic glucose sensing via the CREB coactivator CRTC2
    • Epub 2008/03/08 319/5868/1402, PubMed PMID: 18323454.
    • Dentin R, Hedrick S, Xie J, Yates J, 3rd, Montminy M. Hepatic glucose sensing via the CREB coactivator CRTC2. Science (2008) 319(5868):1402-5. Epub 2008/03/08. doi: 319/5868/1402 [pii] 10.1126/science.1151363. PubMed PMID: 18323454.
    • (2008) Science , vol.319 , Issue.5868 , pp. 1402-1405
    • Dentin, R.1    Hedrick, S.2    Xie, J.3    Yates III, J.4    Montminy, M.5
  • 37
    • 84900408035 scopus 로고    scopus 로고
    • High glucose induced O-GlcNAcylated carbohydrate response element-binding protein (ChREBP) mediates mesangial cell lipogenesis and fibrosis: the possible role in the development of diabetic nephropathy
    • PubMed PMID: 24616092; PubMed Central PMCID: PMC4036358.
    • Park MJ, Kim DI, Lim SK, Choi JH, Han HJ, Yoon KC, et al. High glucose induced O-GlcNAcylated carbohydrate response element-binding protein (ChREBP) mediates mesangial cell lipogenesis and fibrosis: the possible role in the development of diabetic nephropathy. J Biol Chem (2014) 289(19):13519-30. Epub 2014/03/13. doi: M113.530139 [pii] 10.1074/jbc. M113.530139. PubMed PMID: 24616092; PubMed Central PMCID: PMC4036358.
    • (2014) J Biol Chem , vol.289 , Issue.19 , pp. 13519-13530
    • Park, M.J.1    Kim, D.I.2    Lim, S.K.3    Choi, J.H.4    Han, H.J.5    Yoon, K.C.6
  • 38
    • 84863067866 scopus 로고    scopus 로고
    • Loss of FXR protects against diet-induced obesity and accelerates liver carcinogenesis in ob/ob mice
    • Epub 2012/01/21 me.2011-1157, PubMed PMID: 22261820; PubMed Central PMCID: PMC3275160.
    • Zhang Y, Ge X, Heemstra LA, Chen WD, Xu J, Smith JL, et al. Loss of FXR protects against diet-induced obesity and accelerates liver carcinogenesis in ob/ob mice. Mol Endocrinol (2012) 26(2):272-80. Epub 2012/01/21. doi: me.2011-1157 [pii] 10.1210/me.2011-1157. PubMed PMID: 22261820; PubMed Central PMCID: PMC3275160.
    • (2012) Mol Endocrinol , vol.26 , Issue.2 , pp. 272-280
    • Zhang, Y.1    Ge, X.2    Heemstra, L.A.3    Chen, W.D.4    Xu, J.5    Smith, J.L.6
  • 39
    • 84899482356 scopus 로고    scopus 로고
    • Glucose-lowering effects of intestinal bile acid sequestration through enhancement of splanchnic glucose utilization
    • Epub 2014/04/16, PubMed PMID: 24731596.
    • Prawitt J, Caron S, Staels B. Glucose-lowering effects of intestinal bile acid sequestration through enhancement of splanchnic glucose utilization. Trends Endocrinol Metab (2014) 25(5):235-44. Epub 2014/04/16. doi: S1043-2760(14)00054-X [pii] 10.1016/j.tem.2014.03.007. PubMed PMID: 24731596.
    • (2014) Trends Endocrinol Metab , vol.25 , Issue.5 , pp. 235-244
    • Prawitt, J.1    Caron, S.2    Staels, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.