메뉴 건너뛰기




Volumn 748, Issue , 2015, Pages 45-53

Baicalein protects against polymicrobial sepsis-induced liver injury via inhibition of inflammation and apoptosis in mice

Author keywords

Apoptosis; Baicalein; Inflammation; Liverinjury; Sepsis

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BAICALEIN; CASPASE 3; CASPASE 7; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MACROPHAGE MIGRATION INHIBITION FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; FLAVANONE DERIVATIVE; ISOMERASE; MIF PROTEIN, MOUSE; PROTECTIVE AGENT;

EID: 84920156684     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.12.014     Document Type: Article
Times cited : (72)

References (42)
  • 1
    • 0038348601 scopus 로고    scopus 로고
    • Nuclear factor-kappaB and its role in sepsis-associated organ failure
    • E. Abraham Nuclear factor-kappaB and its role in sepsis-associated organ failure J. Infect. Dis 187 Suppl. 2 2003 S364 S369
    • (2003) J. Infect. Dis , vol.187 , pp. 364-S369
    • Abraham, E.1
  • 2
    • 26244452958 scopus 로고    scopus 로고
    • Genetic polymorphisms and sepsis
    • J. Arcaroli, M.B. Fessler, and E. Abraham Genetic polymorphisms and sepsis Shock 24 2005 300 312
    • (2005) Shock , vol.24 , pp. 300-312
    • Arcaroli, J.1    Fessler, M.B.2    Abraham, E.3
  • 3
    • 0029903114 scopus 로고    scopus 로고
    • Sir Isaac Newton, sepsis, SIRS, and CARS
    • R.C. Bone Sir Isaac Newton, sepsis, SIRS, and CARS Crit. Care Med. 24 1996 1125 1128
    • (1996) Crit. Care Med. , vol.24 , pp. 1125-1128
    • Bone, R.C.1
  • 7
    • 41849098143 scopus 로고    scopus 로고
    • Management of sepsis in patients with liver failure
    • J.M. Canabal, and D.J. Kramer Management of sepsis in patients with liver failure Curr. Opin. Crit. Care 14 2008 189 197
    • (2008) Curr. Opin. Crit. Care , vol.14 , pp. 189-197
    • Canabal, J.M.1    Kramer, D.J.2
  • 9
    • 84883645320 scopus 로고    scopus 로고
    • Baicalein inhibits the invasion and metastatic capabilities of hepatocellular carcinoma cells via down-regulation of the ERK pathway
    • K. Chen, S. Zhang, Y. Ji, J. Li, P. Ren, H. Liang, R. Yang, and J. Li, Z. Baicalein inhibits the invasion and metastatic capabilities of hepatocellular carcinoma cells via down-regulation of the ERK pathway PLoS One 8 2013 e72927
    • (2013) PLoS One , vol.8 , pp. 72927
    • Chen, K.1    Zhang, S.2    Ji, Y.3    Li, J.4    Ren, P.5    Liang, H.6    Yang, R.7    Li, Z.J.8
  • 10
    • 33846858005 scopus 로고    scopus 로고
    • Protective effect of baicalein against endotoxic shock in rats in vivo and in vitro
    • P.Y. Cheng, Y.M. Lee, Y.S. Wu, T.W. Chang, J.S. Jin, and M.H. Yen Protective effect of baicalein against endotoxic shock in rats in vivo and in vitro Biochem. Pharmacol. 73 2007 793 804
    • (2007) Biochem. Pharmacol. , vol.73 , pp. 793-804
    • Cheng, P.Y.1    Lee, Y.M.2    Wu, Y.S.3    Chang, T.W.4    Jin, J.S.5    Yen, M.H.6
  • 11
    • 0034927828 scopus 로고    scopus 로고
    • Hepatic response to sepsis: Interaction between coagulation and inflammatory processes
    • J.F. Dhainaut, N. Marin, A. Mignon, and C. Vinsonneau Hepatic response to sepsis: interaction between coagulation and inflammatory processes Crit. Care Med. 29 2001 S42 S47
    • (2001) Crit. Care Med. , vol.29 , pp. 42-S47
    • Dhainaut, J.F.1    Marin, N.2    Mignon, A.3    Vinsonneau, C.4
  • 12
    • 70349307058 scopus 로고    scopus 로고
    • A pivotal role of endothelial-specific NF-kappaB signaling in the pathogenesis of septic shock and septic vascular dysfunction
    • J. Ding, D. Song, X. Ye, and S.F. Liu A pivotal role of endothelial-specific NF-kappaB signaling in the pathogenesis of septic shock and septic vascular dysfunction J. Immunol. 183 2009 4031 4038
    • (2009) J. Immunol. , vol.183 , pp. 4031-4038
    • Ding, J.1    Song, D.2    Ye, X.3    Liu, S.F.4
  • 15
    • 84888395956 scopus 로고    scopus 로고
    • Dual role of chloroquine in liver ischemia reperfusion injury: Reduction of liver damage in early phase, but aggravation in late phase
    • H. Fang, A. Liu, U. Dahmen, and O. Dirsch Dual role of chloroquine in liver ischemia reperfusion injury: reduction of liver damage in early phase, but aggravation in late phase Cell Death Dis. 4 2013 e694
    • (2013) Cell Death Dis. , vol.4 , pp. 694
    • Fang, H.1    Liu, A.2    Dahmen, U.3    Dirsch, O.4
  • 16
    • 70449370069 scopus 로고    scopus 로고
    • Long-term baicalin administration ameliorates metabolic disorders and hepatic steatosis in rats given a high-fat diet
    • H.X. Guo, D.H. Liu, Y. Ma, J.F. Liu, Y. Wang, Z.Y. Du, X. Wang, J.K. Shen, and H.L. Peng Long-term baicalin administration ameliorates metabolic disorders and hepatic steatosis in rats given a high-fat diet Acta Pharmacol. Sin. 30 2009 1505 1512
    • (2009) Acta Pharmacol. Sin. , vol.30 , pp. 1505-1512
    • Guo, H.X.1    Liu, D.H.2    Ma, Y.3    Liu, J.F.4    Wang, Y.5    Du, Z.Y.6    Wang, X.7    Shen, J.K.8    Peng, H.L.9
  • 19
    • 21244488115 scopus 로고    scopus 로고
    • Protective effects of baicalein on tert-butyl hydroperoxide-induced hepatic toxicity in rat hepatocytes
    • J.M. Hwang, T.H. Tseng, Y.Y. Tsai, H.J. Lee, F.P. Chou, C.J. Wang, and C.Y. Chu Protective effects of baicalein on tert-butyl hydroperoxide-induced hepatic toxicity in rat hepatocytes J. Biomed. Sci. 12 2005 389 397
    • (2005) J. Biomed. Sci. , vol.12 , pp. 389-397
    • Hwang, J.M.1    Tseng, T.H.2    Tsai, Y.Y.3    Lee, H.J.4    Chou, F.P.5    Wang, C.J.6    Chu, C.Y.7
  • 20
    • 0029101578 scopus 로고
    • Liver injuries induced by herbal medicine, syo-saiko-to (xiao-chai-hu-tang)
    • S. Itoh, K. Marutani, T. Nishijima, S. Matsuo, and M. Itabashi Liver injuries induced by herbal medicine, syo-saiko-to (xiao-chai-hu-tang) Dig. Dis. Sci. 40 1995 1845 1848
    • (1995) Dig. Dis. Sci. , vol.40 , pp. 1845-1848
    • Itoh, S.1    Marutani, K.2    Nishijima, T.3    Matsuo, S.4    Itabashi, M.5
  • 21
    • 28244467218 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase-dependent chemokine production, leukocyte recruitment, and hepatocellular apoptosis in endotoxemic liver injury
    • D. Klintman, X. Li, S. Santen, R. Schramm, B. Jeppsson, and H. Thorlacius p38 mitogen-activated protein kinase-dependent chemokine production, leukocyte recruitment, and hepatocellular apoptosis in endotoxemic liver injury Ann. Surg. 242 2005 830 838
    • (2005) Ann. Surg. , vol.242 , pp. 830-838
    • Klintman, D.1    Li, X.2    Santen, S.3    Schramm, R.4    Jeppsson, B.5    Thorlacius, H.6
  • 22
    • 34247158279 scopus 로고    scopus 로고
    • Incidence and prognosis of early hepatic dysfunction in critically ill patients - A prospective multicenter study
    • L. Kramer, B. Jordan, W. Druml, P. Bauer, and P.G. Metnitz Incidence and prognosis of early hepatic dysfunction in critically ill patients - a prospective multicenter study Crit. Care Med. 35 2007 1099 1104
    • (2007) Crit. Care Med. , vol.35 , pp. 1099-1104
    • Kramer, L.1    Jordan, B.2    Druml, W.3    Bauer, P.4    Metnitz, P.G.5
  • 23
  • 24
    • 79955484515 scopus 로고    scopus 로고
    • Baicalein, an active component of Scutellaria baicalensis Georgi, improves cardiac contractile function in endotoxaemic rats via induction of heme oxygenase-1 and suppression of inflammatory responses
    • Y.M. Lee, P.Y. Cheng, L.S. Chim, C.W. Kung, S.M. Ka, M.T. Chung, and J.R. Sheu Baicalein, an active component of Scutellaria baicalensis Georgi, improves cardiac contractile function in endotoxaemic rats via induction of heme oxygenase-1 and suppression of inflammatory responses J. Ethnopharmacol. 135 2011 179 185
    • (2011) J. Ethnopharmacol. , vol.135 , pp. 179-185
    • Lee, Y.M.1    Cheng, P.Y.2    Chim, L.S.3    Kung, C.W.4    Ka, S.M.5    Chung, M.T.6    Sheu, J.R.7
  • 25
    • 84908446758 scopus 로고    scopus 로고
    • Safety, tolerability, and pharmacokinetics of a single ascending dose of baicalein chewable tablets in healthy subjects
    • M. Li, A. Shi, H. Pang, W. Xue, Y. Li, G. Cao, B. Yan, F. Dong, K. Li, W. Xiao, G. He, G. Du, and X. Hu Safety, tolerability, and pharmacokinetics of a single ascending dose of baicalein chewable tablets in healthy subjects J. Ethnopharmacol. 156 2014 210 215
    • (2014) J. Ethnopharmacol. , vol.156 , pp. 210-215
    • Li, M.1    Shi, A.2    Pang, H.3    Xue, W.4    Li, Y.5    Cao, G.6    Yan, B.7    Dong, F.8    Li, K.9    Xiao, W.10    He, G.11    Du, G.12    Hu, X.13
  • 26
    • 84918790140 scopus 로고    scopus 로고
    • Baicalein pretreatment protects against liver ischemia/reperfusion injury via inhibition of NF-κB pathway in mice
    • A. Liu, L. Huang, H. Fan, H. Fang, Y. Yang, S. Liu, J. Hu, Q. Hu, O. Dirsch, and U. Dahmen Baicalein pretreatment protects against liver ischemia/reperfusion injury via inhibition of NF-κB pathway in mice Int. Immunopharmacol. 24 2015 72 79
    • (2015) Int. Immunopharmacol. , vol.24 , pp. 72-79
    • Liu, A.1    Huang, L.2    Fan, H.3    Fang, H.4    Yang, Y.5    Liu, S.6    Hu, J.7    Hu, Q.8    Dirsch, O.9    Dahmen, U.10
  • 27
    • 84879526538 scopus 로고    scopus 로고
    • Chronic lithium treatment protects against liver ischemia/reperfusion injury in rats
    • A. Liu, H. Fang, U. Dahmen, and O. Dirsch Chronic lithium treatment protects against liver ischemia/reperfusion injury in rats Liver Transpl. 19 2013 762 772
    • (2013) Liver Transpl. , vol.19 , pp. 762-772
    • Liu, A.1    Fang, H.2    Dahmen, U.3    Dirsch, O.4
  • 28
    • 84861976686 scopus 로고    scopus 로고
    • Baicalein protects human melanocytes from H(2)O(2)-induced apoptosis via inhibiting mitochondria-dependent caspase activation and the p38 MAPK pathway
    • B. Liu, Z. Jian, Q. Li, K. Li, Z. Wang, L. Liu, L. Tang, X. Yi, H. Wang, C. Li, and T. Gao Baicalein protects human melanocytes from H(2)O(2)-induced apoptosis via inhibiting mitochondria-dependent caspase activation and the p38 MAPK pathway Free Radic. Biol. Med. 53 2012 183 193
    • (2012) Free Radic. Biol. Med. , vol.53 , pp. 183-193
    • Liu, B.1    Jian, Z.2    Li, Q.3    Li, K.4    Wang, Z.5    Liu, L.6    Tang, L.7    Yi, X.8    Wang, H.9    Li, C.10    Gao, T.11
  • 29
    • 17144376810 scopus 로고    scopus 로고
    • High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal
    • M.T. Lotze, and K.J. Tracey High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal Nat. Rev. Immunol. 5 2005 331 342
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 331-342
    • Lotze, M.T.1    Tracey, K.J.2
  • 30
    • 0038578608 scopus 로고    scopus 로고
    • Novel strategies for the treatment of sepsis
    • N.C. Riedemann, R.F. Guo, and P.A. Ward Novel strategies for the treatment of sepsis Nat. Med 9 2003 517 524
    • (2003) Nat. Med , vol.9 , pp. 517-524
    • Riedemann, N.C.1    Guo, R.F.2    Ward, P.A.3
  • 31
    • 0035229054 scopus 로고    scopus 로고
    • Evolution of an immune suppressive macrophage phenotype as a product of P38 MAPK activation in polymicrobial sepsis
    • G.Y. Song, C.S. Chung, D. Jarrar, I.H. Chaudry, and A. Ayala Evolution of an immune suppressive macrophage phenotype as a product of P38 MAPK activation in polymicrobial sepsis Shock 15 2001 42 48
    • (2001) Shock , vol.15 , pp. 42-48
    • Song, G.Y.1    Chung, C.S.2    Jarrar, D.3    Chaudry, I.H.4    Ayala, A.5
  • 32
    • 76549100355 scopus 로고    scopus 로고
    • Antifibrotic effects of chronic baicalein administration in a CCl4 liver fibrosis model in rats
    • H. Sun, Q.M. Che, X. Zhao, and X.P. Pu Antifibrotic effects of chronic baicalein administration in a CCl4 liver fibrosis model in rats Eur. J. Pharmacol. 631 2010 53 60
    • (2010) Eur. J. Pharmacol. , vol.631 , pp. 53-60
    • Sun, H.1    Che, Q.M.2    Zhao, X.3    Pu, X.P.4
  • 35
    • 34547652674 scopus 로고    scopus 로고
    • National estimates of severe sepsis in United States emergency departments
    • H.E. Wang, N.I. Shapiro, D.C. Angus, and D.M. Yealy National estimates of severe sepsis in United States emergency departments Crit. Care Med. 35 2007 1928 1936
    • (2007) Crit. Care Med. , vol.35 , pp. 1928-1936
    • Wang, H.E.1    Shapiro, N.I.2    Angus, D.C.3    Yealy, D.M.4
  • 37
    • 78149469030 scopus 로고    scopus 로고
    • Baicalein inhibits nuclear factor-kappaB and apoptosis via c-FLIP and MAPK in d-GalN/LPS induced acute liver failure in murine models
    • Y.L. Wu, L.H. Lian, Y. Wan, and J.X. Nan Baicalein inhibits nuclear factor-kappaB and apoptosis via c-FLIP and MAPK in d-GalN/LPS induced acute liver failure in murine models Chem. Biol. Interact. 188 2010 526 534
    • (2010) Chem. Biol. Interact. , vol.188 , pp. 526-534
    • Wu, Y.L.1    Lian, L.H.2    Wan, Y.3    Nan, J.X.4
  • 38
    • 84912009597 scopus 로고    scopus 로고
    • Treatment with baicalein attenuates methionine-choline deficient diet-induced non-alcoholic steatohepatitis in rats
    • H.G. Xin, B.B. Zhang, Z.Q. Wu, X.F. Hang, W.S. Xu, W. Ni, R.Q. Zhang, and X.H. Miao Treatment with baicalein attenuates methionine-choline deficient diet-induced non-alcoholic steatohepatitis in rats Eur. J. Pharmacol. 738 2014 310 318
    • (2014) Eur. J. Pharmacol. , vol.738 , pp. 310-318
    • Xin, H.G.1    Zhang, B.B.2    Wu, Z.Q.3    Hang, X.F.4    Xu, W.S.5    Ni, W.6    Zhang, R.Q.7    Miao, X.H.8
  • 39
    • 84907840194 scopus 로고    scopus 로고
    • The role of the liver in sepsis
    • J. Yan, S. Li, and S. Li The role of the liver in sepsis Int. Rev. Immunol. 33 2014 498 510
    • (2014) Int. Rev. Immunol. , vol.33 , pp. 498-510
    • Yan, J.1    Li, S.2    Li, S.3
  • 41
    • 84880666556 scopus 로고    scopus 로고
    • Baicalein selectively induces apoptosis in activated lymphocytes and ameliorates concanavalin a-induced hepatitis in mice
    • Y. Zhang, L. Shan, Y. Hua, D. Wang, H. Zeng, R. Liu, W. Zhang, and Z. Hu Baicalein selectively induces apoptosis in activated lymphocytes and ameliorates concanavalin a-induced hepatitis in mice PLoS One 8 2013 e69592
    • (2013) PLoS One , vol.8 , pp. 69592
    • Zhang, Y.1    Shan, L.2    Hua, Y.3    Wang, D.4    Zeng, H.5    Liu, R.6    Zhang, W.7    Hu, Z.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.