Incidence and prognosis of early hepatic dysfunction in critically ill patients - A prospective multicenter study

Critical Care Medicine

Volumn 35, Issue 4, 2007, Pages 1099-1104

  Kramer, Ludwig ^a   Jordan, Barbara ^a   Druml, Wilfred ^a   Bauer, Peter ^a   Metnitz, Philipp G H ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Bilirubin; Epidemiology; Hepatic failure; Liver; Outcome

Indexed keywords

BILIRUBIN;

ADULT; ARTICLE; BILIRUBIN BLOOD LEVEL; CONFIDENCE INTERVAL; CONTROLLED STUDY; CRITICALLY ILL PATIENT; DISEASE ASSOCIATION; FEMALE; HUMAN; INCIDENCE; INTENSIVE CARE UNIT; LIVER CIRRHOSIS; LIVER DYSFUNCTION; LIVER FAILURE; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; RISK ASSESSMENT;

EID: 34247158279     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000259462.97164.A0     Document Type: Article

References (39)

1. Vincent JL, Ferreira F, Moreno R: Scoring systems for assessing organ dysfunction and survival. Crit Care Clin 2000; 16:353-366
2. Pastor CM, Suter PM: Hepatic hemodynamics and cell functions in human and experimental sepsis. Anesth Analg 1999; 89:344-352
3. Tran DD, Groeneveld AB, van der Meulen J, et al: Age, chronic disease, sepsis, organ system failure, and mortality in a medical intensive care unit. Crit Care Med 1990; 18:474-479
4. Hebert PC, Drummond AJ, Singer J, et al: A simple multiple system organ failure scoring system predicts mortality of patients who have sepsis syndrome. Chest 1993; 104:230-235
5. Fagon JY, Chastre J, Novara A, et al: Characterization of intensive care unit patients using a model based on the presence or absence of organ dysfunctions and/or infection: The ODIN model. Intensive Care Med 1993; 19:137-144
6. Moseley RH: Sepsis and cholestasis. Clin Liver Dis 2004; 8:83-94
7. Feld JJ, Dinh H, Arenovich T, et al: Autoimmune hepatitis: Effect of symptoms and cirrhosis on natural history and outcome. Hepatology 2005; 42:53-62
8. Kamath PS, Wiesner RH, Malinchoc M, et al: A model to predict survival in patients with end-stage liver disease. Hepatology 2001; 33:464-470
9. O'Grady JG, Alexander GJM, Hayllar KM, et al: Early indicators of prognosis in fulminant hepatic failure. Gastroenterology 1989; 97:439-445
10. Bernard GR: Quantification of organ dysfunction: Seeking standardization. Crit Care Med 1998; 26:1767-1800
11. Moreno R, Vincent JL, Matos R, et al: The use of maximum SOFA score to quantify organ dysfunction/failure in intensive care. Intensive Care Med 1999; 25:686-896
12. Brienza N, Dalfino L, Cinnella G, et al: Jaundice in critical illness: Promoting factors of a concealed reality. Intensive Care Med 2006; 32:267-274
13. Szabo G, Romics L Jr, Frendl G: Liver in sepsis and systemic inflammatory response syndrome. Clin Liver Dis 2002; 6:1045-1066
14. Metnitz PhGH, Vesely H, Valentin A, et al: Evaluation of an interdisciplinary data set for national ICU assessment. Crit Care Med 1999; 27:1486-1491
15. ASDI. Available at: http://www.asdi.at
16. Metnitz PGH, Steltzer H, Popow C, et al: Definition and evaluation of a documentation standard for intensive care medicine: The ASDI pilot project. Wien Klin Wochenschr 1997; 109:132-138
17. Le Gall JR, Lemeshow S, Saulnier F: A new simplified acute physiology score (SAPS II) based on a European/North American multicenter study. JAMA 1993; 270:2957-2963
18. Le Gall JR, Klar J, Lemeshow S, et al: The logistic organ dysfunction system. A new way to assess organ dysfunction in the intensive care unit. JAMA 1996; 276:802-810
19. Miranda DR, De Rijk A, Schaufeli W: Simplified therapeutic intervention scoring system: The TISS-28 items - Results from a multicenter study. Crit Care Med 1996; 24:64-73
20. Hosmer DW, Lemeshow S: Confidence interval estimates of an index of quality performance based on logistic regression models. Stat Med 1995; 14:2161-2172
21. Harbrecht BG, Zenati MS, Doyle HR, et al: Hepatic dysfunction increases length of stay and risk of death after injury. J Trauma 2002; 53:517-523
22. Chan HL, Kwan AC, To KF, et al: Clinical significance of hepatic derangement in severe acute respiratory syndrome. World J Gastroenterol 2005; 11:2148-2153
23. Marshall JC, Cook DJ, Christou NV, et al: Multiple organ dysfunction score: A reliable descriptor of a complex clinical outcome. Crit Care Med 1995; 23:1638-1652
24. Lefering R, Goris RJ, van Nieuwenhoven EJ, et al: Revision of the multiple organ failure score. Langenbecks Arch Surg 2002; 387:14-20
25. Mullin EJ, Metcalfe MS, Maddern GJ: How much liver resection is too much? Am J Surg 2005; 190:87-97
26. Hessel EA II: Abdominal organ injury after cardiac surgery. Semin Cardiothorac Vasc Anesth 2004;8:243-263
27. Talmor M, Hydo L, Barie PS: Relationship of systemic inflammatory response syndrome to organ dysfunction, length of stay, and mortality in critical surgical illness: Effect of intensive care unit resuscitation. Arch Surg 1999; 134:81-87
28. Bolder U, Ton-Nu HT, Schteingart CD, et al: Hepatocyte transport of bile acids and organic anions in endotoxemic rats: Impaired uptake and secretion. Gastroenterology 1997:214-225
29. Dhainaut JF, Marin N, Mignon A, et al: Hepatic response to sepsis: interaction between coagulation and inflammatory processes. Crit Care Med 2001; 29(Suppl 7):S42-S47
30. Tu W, Satoi S, Zhang Z, et al: Hepatocellular dysfunction induced by nitric oxide production in hepatocytes isolated from rats with sepsis. Shock 2003; 19:373-377
31. Banks JG, Foulis AK, Ledingham IM, et al: Liver function in septic shock. J Clin Pathol 1982; 35:1249-1252
32. Franson TR, LaBrecque DR, Buggy BP, et al: Serial bilirubin determinations as a prognostic marker in clinical infections. Am J Med Sci 1989; 297:149-152
33. Michalopoulos A, Alivizatos P, Geroulanos S: Hepatic dysfunction following cardiac surgery: Determinants and consequences. Hepatogastroenterology 1997; 44:779-783
34. Arai T, Yoshikai Y, Kamiya J, et al: Bilirubin impairs bactericidal activity of neutrophils through an antioxidant mechanism in vitro. J Surg Res 2001; 96:107-113
35. Briegel J, Forst H, Haller M, et al: Stress doses of hydrocortisone reverse hyperdynamic septic shock: A prospective, randomized, double-blind, single-center study. Crit Care Med 1999; 27:723-732
36. Micek ST, Roubinian N, Heuring T, et al: Before-after study of a standardized hospital order set for the management of septic shock. Crit Care Med 2006; 34:2707-2713
37. Han MK, Hyzy R: Advances in critical care management of hepatic failure and insufficiency. Crit Care Med 2006; 34(Suppl 9):S225-S231
38. Vincent JL, de Mendonca A, Cantraine F, et al: Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: Results of a multicenter, prospective study. Crit Care Med 1998; 26:1793-1800
39. Metnitz PG, Moreno RP, Almeida E, et al: SAPS 3 - From evaluation of the patient to evaluation of the intensive care unit. Part 1: Objectives, methods and cohort description. Intensive Care Med 2005; 31:1336-1344