Peptides as skin penetration enhancers: Mechanisms of action

Journal of Controlled Release

Volumn 199, Issue , 2015, Pages 168-178

  Kumar, Sunny ^a,b   Zakrewsky, Michael ^a,b   Chen, Ming ^a,b   Menegatti, Stefano ^a,b   Muraski, John A ^c   Mitragotri, Samir ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Santa Barbara   (United States)

^c Convoy Therapeutics ^*  (United States)

Author keywords

Cell penetrating peptide; Cyclosporine; Keratin; Topical; Transcellular; Transporter

Indexed keywords

DRUG PRODUCTS; FOURIER TRANSFORM INFRARED SPECTROSCOPY; HYDROPHOBICITY; KERATIN; MACROMOLECULES; PEPTIDES; PROTEINS; SKIN; SPECTROSCOPIC ANALYSIS;

CELL-PENETRATING PEPTIDE; CYCLOSPORINE; TOPICAL; TRANSCELLULAR; TRANSPORTER;

SURFACE PLASMON RESONANCE;

CELL PENETRATING PEPTIDE; CYCLOSPORIN A; DERMIS LOCALIZING PEPTIDE; KERATIN; PENETRATION ENHANCING AGENT; POLYARGININE; SKIN LIPID; SKIN PENETRATING LINEAR PEPTIDE; SKIN PENETRATING PEPTIDE; SPACE PEPTIDE; TD 1 PEPTIDE; UNCLASSIFIED DRUG; CYCLOSPORIN; DRUG CARRIER; LIPID; PEPTIDE;

ARTICLE; COMPUTER MODEL; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG MECHANISM; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HYDROPHILICITY; HYDROPHOBICITY; IN VITRO STUDY; INFRARED SPECTROSCOPY; ISOELECTRIC POINT; KERATINOCYTE; MACROMOLECULE; MOLECULAR DOCKING; PH; PROTEIN SECONDARY STRUCTURE; SKIN CONDUCTANCE; SKIN PENETRATION; SKIN WATER LOSS; CELL CULTURE; CHEMISTRY; COMPUTER SIMULATION; DRUG EFFECTS; METABOLISM; SKIN; SKIN ABSORPTION; STRUCTURE ACTIVITY RELATION; THERMOREGULATION;

CELLS, CULTURED; COMPUTER SIMULATION; CYCLOSPORINE; DRUG CARRIERS; HUMANS; KERATINOCYTES; KERATINS; LIPIDS; PEPTIDES; SKIN; SKIN ABSORPTION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STRUCTURE-ACTIVITY RELATIONSHIP; WATER LOSS, INSENSIBLE;

EID: 84920154826     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.12.006     Document Type: Article

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