Modifications induced on stratum corneum structure after in vitro iontophoresis: ATR-FTIR and X-ray scattering studies

Journal of Controlled Release

Volumn 42, Issue 2, 1996, Pages 165-173

  Jadoul, Anne ^a   Doucet, Jean ^b   Durand, Dominique ^b   Préat, Véronique ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

ATR FTIR; Iontophoresis; Skin; Stratum corneum; X ray scattering

Indexed keywords

ANIMAL TISSUE; ARTICLE; HUMAN; HUMAN TISSUE; HYDRATION; INFRARED SPECTROSCOPY; IONTOPHORESIS; LIPID BILAYER; MEMBRANE FLUIDITY; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; RADIATION SCATTERING; RAT; STRATUM CORNEUM;

EID: 0030296250     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/0168-3659(96)01452-6     Document Type: Article

References (22)

1. [1] R.O. Potts and M.L. Francoeur, The influence of s.c. morphology on water permeability, J. Invest. Dermatol. 96 (1991) 495-499.
2. [2] Y.W. Chien, Advances in transdermal systemic drug delivery. Drugs Future 13 (1988) 343-362.
3. [3] R. Potts, Physical characterization of the stratum corneum: the relationship of mechanical and barrier properties to lipid and protein structure. in: J. Hadgraft and R. Guy (Eds.) Transdermal Drug Delivery, Marcel Dekker, New York, 1989, pp. 23-57.
4. [4] C. Cullander, What are the pathways of iontophoretic current flow through mammalian skin ?. Adv. Drug Del. Rev. 9 (1992) 119-135.
5. [5] G.M. Golden, J.E. McKie and R.O. Potts, Role of stratum corneum lipid fluidity in transdermal drug flux. J. Pharm. Sci. 76 (1987) 25-28.
6. [6] A. Naik, L. Pechtold, R.O. Potts and R.H. Guy, Mechanisms of skin penetration enhancement, in vivo, in man. in: K.R. Brain and V.A. Walters (Eds.) Prediction Percutaneous Penetration, Vol. 3b, 1993, pp. 161-165.
7. [7] B.H. Sage, Iontophoresis. in: J. Swarbrick and J.C. Boylan (Eds.) Encyclopedia of Pharmaceutical Technology, Vol. 8, 1993, pp 217-247.
8. [8] P.W. Ledger, Skin biological issues in electrically enhanced transdermal delivery. Adv. Drug Del. Rev. 9 (1992) 289-307.
9. [9] R.D. Green and J. Hadgraft, FT-IR investigations into the effect of iontophoresis on the skin. in: K.R. Brain and V.A. Walters (Eds.) Prediction Percutaneous Penetration, Vol. 3b, 1993, pp. 37-43.
10. [10] S. Thysman, D. Van Neste and V. Préat, Noninvasive investigation of human skin after in vivo iontophoresis, Skin Pharmacol., 8 (1995) 229-236.
11. [11] M.J. Clancy, J. Corish and O.I. Corrigan, A comparison of the effects of electrical current and penetration enhancers on the properties of human skin using spectroscopic (FTIR) and calorimetric methods. Int. J. Pharm. 105 (1994) 47-56.
12. [12] S. Thysman, C. Tasset and V. Préat, Transdermal iontophoresis of fentanyl : delivery and mechanistic analysis. Int. J. Pharm. 101 (1994) 105-113.
13. [13] R.O. Potts, D.B. Guzek, R.R. Harris and J.E. McKie, A noninvasive, in vivo technique to quantitatively measure water concentration of the stratum corneum using attenuated total-reflectance infrared spectroscopy. Arch Dermatol. Res. 277 (1985) 489-495.
14. [14] P.A. D. Edwardson, M. Walker and C. Breheny, Quantitative FT-IR determination of skin hydration following occlusion with hydrocolloid containing adhesive dressings. Int. J. Pharm. 91 (1993) 51-57.
15. [15] M. Gloor, G. Hirsch and U. Willebrandt, On the use of infrared spectroscopy for the in vivo measurement of water content of the horny layer after application of dermatologic oinments. Arch. Dermatol. Res. 271 (1981) 305-313.
16. [16] H.L. Casal and H.H. Mantsch, Polymorphic phase behaviour of phospholipid membranes studied by infrared spectroscopy. Biochem. Biophys. 779 (1984) 381-401.
17. [17] V.H.W Mak, R.O. Potts and R.H. Guy, Does hydration affect intercellular lipid organization in the stratum corneum ?. Pharm. Res. 8 (1991) 1064-1065.
18. [18] J. Garson, J. Doucet, J. Leveque and G. Tsoucaris, Oriented structure in human stratum corneum revealed by X-ray diffraction. J. Invest. Dermatol. 96 (1991) 43-49.
19. [19] J.A. Bouwstra, G.S. Gooris, J.A. van der Spek and W. Bras, Structural investigations of human stratum corneum by small-angle X-ray scattering. J. Invest. Dermatol. 97 (1991) 1005-1012.
20. [20] J.A. Bouwstra, M.A. de Vries, G.S. Gooris, W. Bras, J. Brussee and M. Ponec, Thermodynamic and structural aspects of the skin barrier. J. Control. Release 15 (1991) 209-220.
21. [21] J.A. Bouwstra, G.S. Gooris, M.A. de Vries, J.A. van der Spek and W. Bras, Structure of human stratum corneum as a function of temperature and hydration: a wide angle X-ray diffraction study. Int. J. Pharm. 84 (1992) 205-216.
22. [22] F. Schückler, J.A. Bouwstra, G.S. Gooris and G. Lee, An X-ray diffraction study of some model stratum corneum lipids containing azone and dodecyl-L-pyroglutamate. J. Control. Release 23 (1993) 27-36.