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Volumn 7, Issue 1, 2015, Pages 103-118

Hepcidin-25, Mean Corpuscular Volume, and Ferritin as Predictors of Response to Oral Iron Supplementation in Hemodialysis Patients

Author keywords

Anemia; ferritin; Hemodialysis; Hepcidin; Iron; Mean corpuscular volume

Indexed keywords

ALBUMIN; C REACTIVE PROTEIN; CALCIUM; CONTINUOUS ERYTHROPOIESIS RECEPTOR ACTIVATOR; FERRITIN; FERROUS FUMARATE; HEMOGLOBIN; HEPCIDIN; HUMAN SERUM ALBUMIN; IRON; PARATHYROID HORMONE; PHOSPHORUS; TRANSFERRIN; BIOLOGICAL MARKER; ERYTHROPOIETIN; FERROUS ION; IRON INTAKE;

EID: 84920101236     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu7010103     Document Type: Article
Times cited : (18)

References (44)
  • 1
    • 70049096226 scopus 로고    scopus 로고
    • Parenteral versus oral iron therapy for adults and children with chronic kidney disease
    • Albaramki, J.; Hodson, E.M.; Craig, J.C.; Webster, A.C. Parenteral versus oral iron therapy for adults and children with chronic kidney disease. Cochrane Database Syst. Rev. 2012, 1, CD007857, doi:10.1002/14651858.CD007857.pub2.
    • (2012) Cochrane Database Syst, Rev , vol.1
    • Albaramki, J.1    Hodson, E.M.2    Craig, J.C.3    Webster, A.C.4
  • 2
    • 84861852784 scopus 로고    scopus 로고
    • Efficacy of IV iron compared to oral iron for increment of haemoglobin level in anemic chronic kidney disease patients on erythropoietin therapy
    • Adhikary, L.; Acharya, S. Efficacy of IV iron compared to oral iron for increment of haemoglobin level in anemic chronic kidney disease patients on erythropoietin therapy. JNMA J. Nepal Med. Assoc. 2011, 51, 133–136.
    • (2011) JNMAJ. Nepal Med. Assoc , vol.51 , pp. 133-136
    • Adhikary, L.1    Acharya, S.2
  • 3
    • 84863971685 scopus 로고    scopus 로고
    • Intravenous versus oral iron for treatment of iron deficiency in non-hemodialysis-dependent patients with chronic kidney disease
    • Liles, A.M. Intravenous versus oral iron for treatment of iron deficiency in non-hemodialysis-dependent patients with chronic kidney disease. Am. J. Health Syst. Pharm. 2012, 69, 1206–1211.
    • (2012) Am. J. Healthsyst. Pharm , vol.69 , pp. 1206-1211
    • Liles, A.M.1
  • 5
    • 77955217185 scopus 로고    scopus 로고
    • Effectiveness of oral iron to manage anemia in long-term hemodialysis patients with the use of ultrapure dialysate
    • Tsuchida, A.; Paudyal, B.; Paudyal, P.; Ishii, Y.; Hiromura, K.; Nojima, Y.; Komai, M. Effectiveness of oral iron to manage anemia in long-term hemodialysis patients with the use of ultrapure dialysate. Exp. Ther. Med. 2010, 1, 777–781.
    • (2010) Exp. Ther. Med , vol.1 , pp. 777-781
    • Tsuchida, A.1    Paudyal, B.2    Paudyal, P.3    Ishii, Y.4    Hiromura, K.5    Nojima, Y.6    Komai, M.7
  • 7
    • 80052308801 scopus 로고    scopus 로고
    • Diagnosis and management of iron deficiency anemia in the 21st century
    • Johnson-Wimbley, T.D.; Graham, D.Y. Diagnosis and management of iron deficiency anemia in the 21st century. Ther. Adv. Gastroenterol. 2011, 4, 177–184.
    • (2011) Ther. Adv. Gastroenterol , vol.4 , pp. 177-184
    • Johnson-Wimbley, T.D.1    Graham, D.Y.2
  • 9
    • 63149128149 scopus 로고    scopus 로고
    • Molecular basis of inherited microcytic anemia due to defects in iron acquisition or heme synthesis
    • Iolascon, A.; de Falco, l.; Beaumont, C. Molecular basis of inherited microcytic anemia due to defects in iron acquisition or heme synthesis. Haematologica 2009, 94, 395–408.
    • (2009) Haematologica , vol.94 , pp. 395-408
    • Iolascon, A.1    De Falco, D.2    Beaumont, C.3
  • 10
    • 79955958017 scopus 로고    scopus 로고
    • Hepcidin and iron regulation, 10 years later
    • Ganz, T. Hepcidin and iron regulation, 10 years later. Blood 2011, 117, 4425–4433.
    • (2011) Blood , vol.117 , pp. 4425-4433
    • Ganz, T.1
  • 12
    • 69149095947 scopus 로고    scopus 로고
    • Serum prohepcidin and hepcidin in hemodialyzed patients undergoing iron therapy
    • Malyszko, J.; Malyszko, J.S.; Mysliwiec, M. Serum prohepcidin and hepcidin in hemodialyzed patients undergoing iron therapy. Kidney Blood Press. Res. 2009, 32, 235–238.
    • (2009) Kidney Blood Press, Res , vol.32 , pp. 235-238
    • Malyszko, J.1    Malyszko, J.S.2    Mysliwiec, M.3
  • 14
    • 36249027662 scopus 로고    scopus 로고
    • Association of prohepcidin and hepcidin-25 with erythropoietin response and ferritin in hemodialysis patients
    • Kato, A.; Tsuji, T.; Luo, J.; Sakao, Y.; Yasuda, H.; Hishida, A. Association of prohepcidin and hepcidin-25 with erythropoietin response and ferritin in hemodialysis patients. Am. J. Nephrol. 2008, 28, 115–121.
    • (2008) Am.J. Nephrol , vol.28 , pp. 115-121
    • Kato, A.1    Tsuji, T.2    Luo, J.3    Sakao, Y.4    Yasuda, H.5    Hishida, A.6
  • 16
    • 84863749938 scopus 로고    scopus 로고
    • Wetzels, J.F.; et al. Hepcidin-25 in chronic hemodialysis patients is related to residual kidney function and not to treatment with erythropoiesis stimulating agents
    • Van der Weerd, N.C.; Grooteman, M.P.; Bots, M.L.; van den Dorpel, M.A.; den Hoedt, C.H.; Mazairac, A.H.; Nubé, M.J.; Penne, E.L.; Gaillard, C.A.; Wetzels, J.F.; et al. Hepcidin-25 in chronic hemodialysis patients is related to residual kidney function and not to treatment with erythropoiesis stimulating agents. PLoS One 2012, 7, e39783, doi:10.1371/journal.pone.0039783.
    • (2012) Plos One , vol.7
    • Van Der Weerd, N.C.1    Grooteman, M.P.2    Botsvan Den, M.L.3    Dorpel, M.A.4    Den Hoedt, C.H.5    Mazairac, A.H.6    Nubé, M.J.7    Penne, E.L.8    Gaillard, C.A.9
  • 18
    • 77649206366 scopus 로고    scopus 로고
    • Serum hepcidin-25 levels in patients with chronic kidney disease are independent of glomerular filtration rate
    • Peters, H.P.; Laarakkers, C.M.; Swinkels, D.W.; Wetzels, J.F. Serum hepcidin-25 levels in patients with chronic kidney disease are independent of glomerular filtration rate. Nephrol. Dial. Transplant. 2010, 25, 848–853.
    • (2010) Nephrol. Dial. Transplant , vol.25 , pp. 848-853
    • Peters, H.P.1    Laarakkers, C.M.2    Swinkels, D.W.3    Wetzels, J.F.4
  • 19
    • 84920098429 scopus 로고    scopus 로고
    • Regulation of hepcidin-25 by short-and long-acting rhEPO may be dependent on ferritin and predict the response to rhEPO in hemodialysis patients
    • Takasawa, K.; Tomosugi, N.; Takaeda, C.; Maeda, T.; Ueda, N. Regulation of hepcidin-25 by short-and long-acting rhEPO may be dependent on ferritin and predict the response to rhEPO in hemodialysis patients. Nephron Extra 2014, 4, 55–63.
    • (2014) Nephron Extra , vol.4 , pp. 55-63
    • Takasawa, K.1    Tomosugi, N.2    Takaeda, C.3    Maeda, T.4    Ueda, N.5
  • 20
    • 79952473162 scopus 로고    scopus 로고
    • Serum hepcidin-25 may replace the ferritin index in the Thomas plot in assessing iron status in anemic patients
    • Thomas, C.; Kobold, U.; Balan, S.; Roeddiger, R.; Thomas, L. Serum hepcidin-25 may replace the ferritin index in the Thomas plot in assessing iron status in anemic patients. Int. J. Lab. Hematol. 2011, 33, 187–193.
    • (2011) Int.J. Lab. Hematol , vol.33 , pp. 187-193
    • Thomas, C.1    Kobold, U.2    Balan, S.3    Roeddiger, R.4    Thomas, L.5
  • 21
    • 84872951347 scopus 로고    scopus 로고
    • Hepcidin levels predict nonresponsiveness to oral iron therapy in patients with iron deficiency anemia
    • Bregman, D.B.; Morris, D.; Koch, T.A.; He, A.; Goodnough, L.T. Hepcidin levels predict nonresponsiveness to oral iron therapy in patients with iron deficiency anemia. Am. J. Hematol. 2013, 88, 97–101.
    • (2013) Am. J. Hematol , vol.88 , pp. 97-101
    • Bregman, D.B.1    Morris, D.2    Koch, T.A.3    He, A.4    Goodnough, L.T.5
  • 22
    • 84920093309 scopus 로고    scopus 로고
    • Tselepis, C.; et al. Serum hepcidin-25 and response to intravenous iron in patients with non-dialysis chronic kidney disease
    • Chand, S.; Ward, D.G.; Ng, Z.Y.; Hodson, J.; Kirby, H.; Steele, P.; Rooplal, I.; Bantugon, F.; Iqbal, T.; Tselepis, C.; et al. Serum hepcidin-25 and response to intravenous iron in patients with non-dialysis chronic kidney disease. J. Nephrol. 2014, doi:10.1007/s40620-014-0083-y.
    • (2014) J. Nephrol
    • Chand, S.1    Ward, D.G.2    Ng, Z.Y.3    Hodson, J.4    Kirby, H.5    Steele, P.6    Rooplal, I.7    Bantugon, F.8    Iqbal, T.9
  • 23
    • 33646800565 scopus 로고    scopus 로고
    • Association between transferrin receptor-ferritin index and conventional measures of iron responsiveness in hemodialysis patients
    • Chen, Y.C.; Hung, S.C.; Tarng, D.C. Association between transferrin receptor-ferritin index and conventional measures of iron responsiveness in hemodialysis patients. Am. J. Kidney Dis. 2006, 47, 1036–1044.
    • (2006) Am.J. Kidney Dis , vol.47 , pp. 1036-1044
    • Chen, Y.C.1    Hung, S.C.2    Tarng, D.C.3
  • 24
    • 0035189411 scopus 로고    scopus 로고
    • Treatment of anemia with microencapsulated ferrous fumarate plus ascorbic acid supplied as sprinkles to complementary (Weaning) foods
    • Zlotkin, S.; Arthur, P.; Antwi, K.Y.; Yeung, G. Treatment of anemia with microencapsulated ferrous fumarate plus ascorbic acid supplied as sprinkles to complementary (weaning) foods. Am. J. Clin. Nutr. 2001, 74, 791–795.
    • (2001) Am.J. Clin. Nutr , vol.74 , pp. 791-795
    • Zlotkin, S.1    Arthur, P.2    Antwi, K.Y.3    Yeung, G.4
  • 25
    • 0023710206 scopus 로고
    • Comparing the areas under two or more correlated receiver operating characteristic curves: A nonparametric approach
    • DeLong, E.R.; DeLong, D.M.; Clarke-Pearson, D.L. Comparing the areas under two or more correlated receiver operating characteristic curves: A nonparametric approach. Biometrics 1988, 44, 837–845.
    • (1988) Biometrics , vol.44 , pp. 837-845
    • Delong, E.R.1    Delong, D.M.2    Clarke-Pearson, D.L.3
  • 26
    • 0032935896 scopus 로고    scopus 로고
    • Inflammation enhances cardiovascular risk and mortality in hemodialysis patients
    • Zimmermann, J.; Herrlinger, S.; Pruy, A.; Metzger, T.; Wanner, C. Inflammation enhances cardiovascular risk and mortality in hemodialysis patients. Kidney Int. 1999, 55, 648–658.
    • (1999) Kidney Int , vol.55 , pp. 648-658
    • Zimmermann, J.1    Herrlinger, S.2    Pruy, A.3    Metzger, T.4    Wanner, C.5
  • 28
    • 77957588960 scopus 로고    scopus 로고
    • Intra-individual variability in serum hepcidin precludes its use as a marker of iron status in hemodialysis patients
    • Ford, B.A.; Eby, C.S.; Scott, M.G.; Coyne, D.W. Intra-individual variability in serum hepcidin precludes its use as a marker of iron status in hemodialysis patients. Kidney Int. 2010, 78, 769–773.
    • (2010) Kidney Int , vol.78 , pp. 769-773
    • Ford, B.A.1    Eby, C.S.2    Scott, M.G.3    Coyne, D.W.4
  • 29
    • 77957304252 scopus 로고    scopus 로고
    • Current status of the measurement of blood hepcidin levels in chronic kidney disease
    • Macdougall, I.C.; Malyszko, J.; Hider, R.C.; Bansal, S.S. Current status of the measurement of blood hepcidin levels in chronic kidney disease. Clin. J. Am. Soc. Nephrol. 2010, 5, 1681–1689.
    • (2010) Clin. J. Am. Soc. Nephrol , vol.5 , pp. 1681-1689
    • Macdougall, I.C.1    Malyszko, J.2    Hider, R.C.3    Bansal, S.S.4
  • 30
    • 33744498373 scopus 로고    scopus 로고
    • Plasma prohepcidin positively correlates with hematocrit in chronic hemodialysis patients
    • Hsu, S.P.; Chiang, C.K.; Chien, C.T.; Hung, K.Y. Plasma prohepcidin positively correlates with hematocrit in chronic hemodialysis patients. Blood Purif. 2006, 24, 311–316.
    • (2006) Blood Purif , vol.24 , pp. 311-316
    • Hsu, S.P.1    Chiang, C.K.2    Chien, C.T.3    Hung, K.Y.4
  • 31
    • 84876295741 scopus 로고    scopus 로고
    • Should we reconsider iron administration based on prevailing ferritin and hepcidin concentrations?
    • Nakanishi, T.; Kuragano, T.; Kaibe, S.; Nagasawa, Y.; Hasuike, Y. Should we reconsider iron administration based on prevailing ferritin and hepcidin concentrations? Clin. Exp. Nephrol. 2012, 16, 819–826.
    • (2012) Clin. Exp. Nephrol , vol.16 , pp. 819-826
    • Nakanishi, T.1    Kuragano, T.2    Kaibe, S.3    Nagasawa, Y.4    Hasuike, Y.5
  • 32
    • 0028316906 scopus 로고
    • Serum ferritin, hematocrit and mean corpuscular volume in hemodialysis
    • Goldwasser, P.; Koutelos, T.; Abraham, S.; Avram, M.M. Serum ferritin, hematocrit and mean corpuscular volume in hemodialysis. Nephron 1994, 67, 30–35.
    • (1994) Nephron , vol.67 , pp. 30-35
    • Goldwasser, P.1    Koutelos, T.2    Abraham, S.3    Avram, M.M.4
  • 33
    • 0019520085 scopus 로고
    • Red cell indices and iron stores in patients undergoing haemodialysis
    • Lynn, K.L.; Mitchell, T.R.; Shepperd, J. Red cell indices and iron stores in patients undergoing haemodialysis. Br. Med. J. (Clin. Res. Ed.) 1981, 282, 2096, doi:10.2307/29502570.
    • (1981) Br. Med. J. (Clin. Res. Ed.) , vol.282 , pp. 2096
    • Lynn, K.L.1    Mitchell, T.R.2    Shepperd, J.3
  • 34
    • 0018635880 scopus 로고
    • Iron induced increase in red cell size in haemodialysis patients
    • Gokal, R.; Weatherall, D.J.; Bunch, C. Iron induced increase in red cell size in haemodialysis patients. Q. J. Med. 1979, 48, 393–401.
    • (1979) Q. J. Med , vol.48 , pp. 393-401
    • Gokal, R.1    Weatherall, D.J.2    Bunch, C.3
  • 35
    • 0026726837 scopus 로고
    • Hematologic parameters and iron stores in patients on hemodialysis for chronic renal failure
    • Nuwayri-Salti, N.; Jabre, F.; Daouk, M.; Sa’ab, G.; Salem, Z. Hematologic parameters and iron stores in patients on hemodialysis for chronic renal failure. Clin. Nephrol. 1992, 38, 101–104.
    • (1992) Clin. Nephrol , vol.38 , pp. 101-104
    • Nuwayri-Salti, N.1    Jabre, F.2    Daouk, M.3    Sa’Ab, G.4    Salem, Z.5
  • 36
    • 0020608604 scopus 로고
    • Evaluation of iron status in patients on chronic hemodialysis: Relative usefulness of bone marrow hemosiderin, serum ferritin, transferrin saturation, mean corpuscular volume and red cell protoporphyrin
    • Moreb, J.; Popovtzer, M.M.; Friedlaender, M.M.; Konijn, A.M.; Hershko, C. Evaluation of iron status in patients on chronic hemodialysis: Relative usefulness of bone marrow hemosiderin, serum ferritin, transferrin saturation, mean corpuscular volume and red cell protoporphyrin. Nephron 1983, 35, 196–200.
    • (1983) Nephron , vol.35 , pp. 196-200
    • Moreb, J.1    Popovtzer, M.M.2    Friedlaender, M.M.3    Konijn, A.M.4    Hershko, C.5
  • 37
    • 0030859097 scopus 로고    scopus 로고
    • An evaluation of the effectiveness of oral iron therapy in hemodialysis patients receiving recombinant human erythropoietin
    • Markowitz, G.S.; Kahn, G.A.; Feingold, R.E.; Coco, M.; Lynn, R.I. An evaluation of the effectiveness of oral iron therapy in hemodialysis patients receiving recombinant human erythropoietin. Clin. Nephrol. 1997, 48, 34–40.
    • (1997) Clin. Nephrol , vol.48 , pp. 34-40
    • Markowitz, G.S.1    Kahn, G.A.2    Feingold, R.E.3    Coco, M.4    Lynn, R.I.5
  • 38
    • 84926184950 scopus 로고    scopus 로고
    • Inflammation, high ferritin, and erythropoietin resistance in indigenous maintenance hemodialysis patients from the Top End of Northern Australia
    • Majoni, S.W.; Ellis, J.A.; Hall, H.; Abeyaratne, A.; Lawton, P.D. Inflammation, high ferritin, and erythropoietin resistance in indigenous maintenance hemodialysis patients from the Top End of Northern Australia. Hemodial. Int. 2014, doi:10.1111/hdi.12173.
    • (2014) Hemodial. Int
    • Majoni, S.W.1    Ellis, J.A.2    Hall, H.3    Abeyaratne, A.4    Lawton, P.D.5
  • 39
    • 70350630203 scopus 로고    scopus 로고
    • Plasma hepcidin is a modest predictor of dietary iron bioavailability in humans, whereas oral iron loading, measured by stable-isotope appearance curves, increases plasma hepcidin
    • Zimmermann, M.B.; Troesch, B.; Biebinger, R.; Egli, I.; Zeder, C.; Hurrell, R.F. Plasma hepcidin is a modest predictor of dietary iron bioavailability in humans, whereas oral iron loading, measured by stable-isotope appearance curves, increases plasma hepcidin. Am. J. Clin. Nutr. 2009, 90, 1280–1287.
    • (2009) Am. J. Clin. Nutr , vol.90 , pp. 1280-1287
    • Zimmermann, M.B.1    Troesch, B.2    Biebinger, R.3    Egli, I.4    Zeder, C.5    Hurrell, R.F.6
  • 41
    • 34249304479 scopus 로고    scopus 로고
    • the DRIVE Study Group. Predictors of the response to treatment in anemic hemodialysis patients with high serum ferritin and low transferrin saturation
    • Singh, A.K.; Coyne, D.W.; Shapiro, W.; Rizkala, A.R.; the DRIVE Study Group. Predictors of the response to treatment in anemic hemodialysis patients with high serum ferritin and low transferrin saturation. Kidney Int. 2007, 71, 1163–1171.
    • (2007) Kidney Int , vol.71 , pp. 1163-1171
    • Singh, A.K.1    Coyne, D.W.2    Shapiro, W.3    Rizkala, A.R.4
  • 42
    • 4444229891 scopus 로고    scopus 로고
    • The diagnosis of borderline iron deficiency: Results of a therapeutic trial
    • Wright, C.M.; Kelly, J.; Trail, A.; Parkinson, K.N.; Summerfield, G. The diagnosis of borderline iron deficiency: Results of a therapeutic trial. Arch. Dis. Child. 2004, 89, 1028–1031.
    • (2004) Arch. Dis. Child , vol.89 , pp. 1028-1031
    • Wright, C.M.1    Kelly, J.2    Trail, A.3    Parkinson, K.N.4    Summerfield, G.5
  • 43
    • 0024949151 scopus 로고
    • Prediction and evaluation of the effect of iron treatment in anaemic RA patients
    • Vreugdenhil, G.; Baltus, J.A.; van Eijk, H.G.; Swaak, A.J. Prediction and evaluation of the effect of iron treatment in anaemic RA patients. Clin. Rheumatol. 1989, 8, 352–362.
    • (1989) Clin. Rheumatol , vol.8 , pp. 352-362
    • Vreugdenhil, G.1    Baltus, J.A.2    Van Eijk, H.G.3    Swaak, A.J.4
  • 44
    • 0032949266 scopus 로고    scopus 로고
    • Oral versus intravenous
    • Macdougall, I.C. Strategies for iron supplementation
    • Macdougall, I.C. Strategies for iron supplementation: Oral versus intravenous. Kidney Int. Suppl. 1999, 69, S61–S66.
    • (1999) Kidney Int. Suppl , vol.69 , pp. S61-S66


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