An evaluation of the effectiveness of oral iron therapy in hemodialysis patients receiving recombinant human erythropoietin

Clinical Nephrology

Volumn 48, Issue 1, 1997, Pages 34-40

  Markowitz, G S ^a   Kahn, G A ^a   Feingold, R E ^a   Coco, M ^a   Lynn, R I ^a,b  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b NONE   (United States)

Author keywords

Erythropoietin; Hemodialysis; Iron polysaccharide complex (Niferex); Oral iron; Zinc protoporphyrin (ZPP)

Indexed keywords

FERRITIN; IRON; PROTOPORPHYRIN ZINC; RECOMBINANT ERYTHROPOIETIN; TRANSFERRIN;

ADULT; AGED; ANEMIA; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; ERYTHROPOIESIS; FEMALE; FERRITIN BLOOD LEVEL; HEMATOCRIT; HEMODIALYSIS PATIENT; HUMAN; IRON ABSORPTION; IRON DEFICIENCY; IRON STORAGE; IRON THERAPY; MALE; ORAL DRUG ADMINISTRATION; PATIENT COMPLIANCE; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; TRANSFERRIN BLOOD LEVEL;

ADMINISTRATION, ORAL; ANEMIA; ANEMIA, IRON-DEFICIENCY; DOUBLE-BLIND METHOD; ERYTHROPOIETIN; FEMALE; FERRITINS; FOLLOW-UP STUDIES; HUMANS; IRON; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; PATIENT COMPLIANCE; POLYSACCHARIDES; RECOMBINANT PROTEINS; RENAL DIALYSIS; TIME FACTORS;

EID: 0030859097     PISSN: 03010430     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Aljama P, Ward MK, Pierides AM, Eastham EJ, Ellis HA, Feest TG, Conceicao S, Kerr DN. 1978 Serum Ferritin Concentration: A Reliable Guide to Iron Overload in Uremic and Hemodialyzed Patients. Clin Nephrol 10(3): 101-104
2. Anastassiades EG, Howarth D, Howarth J, Shanks D, Waters HM, Hyde K, Geary CG, Yin JA, Gokal R 1993 Monitoring of Iron Requirements in Renal Patients on Erythropoietin. Nephrol Dial Transplant 8: 846-853
3. Beallo R, Dallman PR, Schoenfeld PY, Humphreys MH 1976 Serum Ferritin and Iron Deficiency in Patients on Chronic Hemodialysis. Trans Am Soc Artif Intern Organs 22: 73-79
4. Bezwoda WR, Derman DP, Bothwell TH, MacPhail AP, Torrance JD, Milne FJ, Meyers AM, Levin J 1981 Iron Absorption in Patients on Regular Dialysis Therapy. Nephron 28 (2): 289
5. Eschbach JW, Egrie JC, Downing MR, Browne JK, Adamson JW 1987 Correction of the Anemia of End-Stage Renal Disease with Recombinant Human Erythropoietin. N Engl J Med 316 (2): 73-78
6. Eschbach JW, Abdulhadi MH, Browne JK, Delano BG, Downing MR, Egrie JC, Evans RW, Friedman EA, Graber SE, Haley NR 1989 Recombinant Human Erythropoietin in Anemic Patients with End-Stage Renal Disease. Ann Intern Med 111 (12): 992-1000
7. Finger M, Lynn RI. Predictors of Iron Deficiency in Hemodialysis Patients Receiving Erythropoietin Therapy. Submitted for Publication
8. Fishbane S, Lynn RI 1995 The Utility of Zinc Protoporphyrin for Predicting the Need for intravenous Iron Therapy in Hemodialysis Patients. Am J Kidney Dis 25 (3): 426-432
9. Hallberg L, Ryttinger L, Solvell L 1966 Side-Effects of Oral Iron Therapy. Acta Med Scand 459 (Suppl): 3-10
10. Hughes RT, Smith T, Hesp R, Hulme B, Dukes DC, Bending MB, Pearson J, Raja KB, Cotes PM, Pippard MJ 1992 Regulation of Iron Absorption in Iron Loaded Subjects with End Stage Renal Disease: Effects of Treatment with Recombinant Human Erythropoietin and Reduction of Iron Stores. Br J Hematol 82: 445-454
11. Hussein S, Prieto J, O'Shea M, Hoffbrand AV, Baillod RA, Moorhead JF 1975 Serum Ferritin Assay and Iron Status in Chronic Renal Failure and Hemodialysis. BMJ 1: 546-548
12. Johnson CA, Rosowski E, Zimmerman SW 1992 A Prospective Open-Label Study Evaluating the Efficacy and Adverse Reactions of the Use of Niferex-150 in ESRD Patients Receiving Epogen. Adv Peril Dial 8: 444-447
13. Labbe RF, Rettmer RL, Shah AG, Turnlund JR. ZPP 1987 Past, Present, and Future. Ann NY Acad Sci 514: 7-14
14. Lipschitz DA, Cook JD, Finch CA 1974 Aclinical Evaluation of Serum Ferritin as an Index of Iron Stores. N Engl J Med 290 (22): 1213-1216
15. Magana L, Dhar SK, Smith EC, Martinez C 1984 Iron Absorption and Utilization in Maintenance Hemodialysis Patients: Oral and Intravenous Routes. Mt Sinai J Med 51 (2): 180-183
16. Milman N, Larsen L 1976 Iron Absorption in Patients with Chronic Uremia Undergoing Regular Hemodialysis. Acta Med Scand. 199; 113-119
17. Moreb J, Popovtzer MM, Friedlaender MM, Konijn AM, Hershko C 1983 Evaluation of Iron Status in Patients on Chronic Hemodialysis: Relative Usefulness of Bone Marrow Hemosiderin. Serum Ferritin, Tsat, Mean Corpuscular Volume and Red Cell Protoporphyrin Nephron 35:196-200
18. Schifman KB, Rivers SL, Finley PR, Thies C 1982 RBC ZPP to Screen Blood Donors for Iron Deficiency Anemia. JAMA 248 (16): 2012-2015
19. Van de Vyver FL, Vanheule AA, Majelyne WM, D'Haese P, Blockx PP, Bekaert AB, Buyssens N, de Keersmaecker W, De Broe ME 1984 Serum Ferritin as a Guide for Iron Stores in Chronic Hemodialysis Patients. Kidney Int 26: 451-458
20. Van Wyck DB 1989 Iron Deficiency in Patients with Dialysis-Associated Anemia During Erythropoietin Therapy: Strategies for Assessment and Therapy. Semin Nephrol 9 (1): 21-24
21. Wingard RL, Parker RA, Ismail N, Hakim RL 1995 Efficacy of Oral Iron Therapy in Patients Receiving Recombinant Human Erythropoietin. Am J Kidney Dis 25 (3): 433-439