메뉴 건너뛰기




Volumn 308, Issue 1, 2015, Pages G56-G62

Glucose-Dependent insulinotropic polypeptide-mediated signaling pathways enhance apical PepT1 expression in intestinal epithelial cells

Author keywords

CDX2 expression; Dipeptide uptake Gly Sar uptake; IEC 6 cells; Intestinal absorptive epithelial cells

Indexed keywords

CALPHOSTIN C; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DERIVATIVE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GASTRIC INHIBITORY POLYPEPTIDE; GLUCAGON LIKE PEPTIDE; GLYCYLSARCOSINE; PEPTIDE TRANSPORTER 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR CDX2; WORTMANNIN; COTRANSPORTER; DIPEPTIDE; EPAC PROTEIN, RAT; GASTRIC INHIBITORY POLYPEPTIDE RECEPTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR; HOMEODOMAIN PROTEIN; HORMONE RECEPTOR; PROTEIN KINASE INHIBITOR; SLC15A1 PROTEIN, RAT;

EID: 84920095181     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00168.2014     Document Type: Article
Times cited : (16)

References (66)
  • 1
    • 0142244159 scopus 로고    scopus 로고
    • Regulation of expression of the intestinal oligopeptide transporter (Pept-1) in health and disease
    • Adibi SA. Regulation of expression of the intestinal oligopeptide transporter (Pept-1) in health and disease. Am J Physiol Gastrointest Liver Physiol 285: G779–G788, 2003
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.285 , pp. G779-G788
    • Adibi, S.A.1
  • 2
    • 0001559825 scopus 로고
    • Digestion and absorption of carbohydrates and proteins
    • 3rd ed.), edited by Johnson L. New York: Raven
    • Alpers DH. Digestion and absorption of carbohydrates and proteins. In: Physiology of the Gastrointestinal Tract (3rd ed.), edited by Johnson L. New York: Raven, 1994, p. 1723–1750
    • (1994) Physiology of the Gastrointestinal Tract , pp. 1723-1750
    • Alpers, D.H.1
  • 5
    • 0036083384 scopus 로고    scopus 로고
    • Thyroid hormone regulates the activity and expression of the peptide transporter PEPT1 in Caco-2 cells
    • Ashida K, Katsura T, Motohashi H, Saito H, Inui K. Thyroid hormone regulates the activity and expression of the peptide transporter PEPT1 in Caco-2 cells. Am J Physiol Gastrointest Liver Physiol 282: G617–G623, 2002
    • (2002) Am J Physiol Gastrointest Liver Physiol , vol.282 , pp. G617-G623
    • Ashida, K.1    Katsura, T.2    Motohashi, H.3    Saito, H.4    Inui, K.5
  • 6
    • 33744906739 scopus 로고    scopus 로고
    • Sp1/Sp3 binding is associated with cell-specific expression of the glucose-dependent insulinotropic polypeptide receptor gene
    • Boylan MO, Jepeal LI, Wolfe MM. Sp1/Sp3 binding is associated with cell-specific expression of the glucose-dependent insulinotropic polypeptide receptor gene. Am J Physiol Endocrinol Metab 290: E1287–E1295, 2006
    • (2006) Am J Physiol Endocrinol Metab , vol.290 , pp. E1287-E1295
    • Boylan, M.O.1    Jepeal, L.I.2    Wolfe, M.M.3
  • 7
    • 84878808238 scopus 로고    scopus 로고
    • Pharmacology, physiology, and mechanisms of incretin hormone action
    • Campbell JE, Drucker DJ. Pharmacology, physiology, and mechanisms of incretin hormone action. Cell Metab 17: 819–837, 2013
    • (2013) Cell Metab , vol.17 , pp. 819-837
    • Campbell, J.E.1    Drucker, D.J.2
  • 9
    • 0031596837 scopus 로고    scopus 로고
    • Functional modulation of P2X2 receptors by cyclic AMP-dependent protein kinase
    • Chow YW, Wang HL. Functional modulation of P2X2 receptors by cyclic AMP-dependent protein kinase. J Neurochem 70: 2606–2612, 1998
    • (1998) J Neurochem , vol.70 , pp. 2606-2612
    • Chow, Y.W.1    Wang, H.L.2
  • 12
    • 1242272750 scopus 로고    scopus 로고
    • The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology
    • Daniel H, Kottra G. The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology. Pflügers Arch 447: 610–618, 2004
    • (2004) Pflügers Arch , vol.447 , pp. 610-618
    • Daniel, H.1    Kottra, G.2
  • 13
    • 77951207195 scopus 로고    scopus 로고
    • Obesity: Genes, brain, gut, and environment
    • Das UN. Obesity: genes, brain, gut, and environment. Nutrition 26: 459–473, 2010
    • (2010) Nutrition , vol.26 , pp. 459-473
    • Das, U.N.1
  • 14
    • 0030945044 scopus 로고    scopus 로고
    • Protein kinase A-dependent stimulation of exocytosis in mouse pancreatic beta-cells by glucose-dependent insulinotropic polypeptide
    • Ding WG, Gromada J. Protein kinase A-dependent stimulation of exocytosis in mouse pancreatic beta-cells by glucose-dependent insulinotropic polypeptide. Diabetes 46: 615–621, 1997
    • (1997) Diabetes , vol.46 , pp. 615-621
    • Ding, W.G.1    Gromada, J.2
  • 16
    • 0026093003 scopus 로고
    • The rat glucagon gene is regulated by a protein kinase A-dependent pathway in pancreatic islet cells
    • Drucker DJ, Campos R, Reynolds R, Stobie K, Brubaker PL. The rat glucagon gene is regulated by a protein kinase A-dependent pathway in pancreatic islet cells. Endocrinology 128: 394–400, 1991
    • (1991) Endocrinology , vol.128 , pp. 394-400
    • Drucker, D.J.1    Campos, R.2    Reynolds, R.3    Stobie, K.4    Brubaker, P.L.5
  • 18
    • 77953957372 scopus 로고    scopus 로고
    • Cyclic AMP signaling in pancreatic islets
    • Furman B, Ong WK, Pyne NJ. Cyclic AMP signaling in pancreatic islets. Adv Exp Med Biol 654: 281–304, 2010
    • (2010) Adv Exp Med Biol , vol.654 , pp. 281-304
    • Furman, B.1    Ong, W.K.2    Pyne, N.J.3
  • 21
    • 77949538387 scopus 로고    scopus 로고
    • Epac: Defining a new mechanism for cAMP action
    • Gloerich M, Bos JL. Epac: defining a new mechanism for cAMP action. Annu Rev Pharmacol Toxicol 50: 355–375, 2010
    • (2010) Annu Rev Pharmacol Toxicol , vol.50 , pp. 355-375
    • Gloerich, M.1    Bos, J.L.2
  • 22
    • 10644293820 scopus 로고    scopus 로고
    • Glucagon-like peptide-1: Regulation of insulin secretion and therapeutic potential
    • Gromada J, Brock B, Schmitz O, Rorsman P. Glucagon-like peptide-1: regulation of insulin secretion and therapeutic potential. Basic Clin Pharmacol Toxicol 95: 252–262, 2004
    • (2004) Basic Clin Pharmacol Toxicol , vol.95 , pp. 252-262
    • Gromada, J.1    Brock, B.2    Schmitz, O.3    Rorsman, P.4
  • 23
    • 77954352048 scopus 로고    scopus 로고
    • +and Cl secretion in guinea pig distal colonic epithelium proceeds via separate cAMP signaling pathways
    • +and Cl secretion in guinea pig distal colonic epithelium proceeds via separate cAMP signaling pathways. Am J Physiol Gastrointest Liver Physiol 299: G81–G95, 2010
    • (2010) Am J Physiol Gastrointest Liver Physiol , vol.299 , pp. G81-G95
    • Halm, S.T.1    Zhang, J.2
  • 25
    • 0025967721 scopus 로고
    • Lack of correlation between activation of cyclic AMP-dependent protein kinase and inhibition of contraction of rat vas deferens by cyclic AMP analogs
    • Hei YJ, MacDonell KL, McNeill JH, Diamond J. Lack of correlation between activation of cyclic AMP-dependent protein kinase and inhibition of contraction of rat vas deferens by cyclic AMP analogs. Mol Pharmacol 39: 233–238, 1991
    • (1991) Mol Pharmacol , vol.39 , pp. 233-238
    • Hei, Y.J.1    Macdonell, K.L.2    Mc neill, J.H.3    Diamond, J.4
  • 26
    • 0043209120 scopus 로고    scopus 로고
    • Intestinal sugar absorption is regulated by phosphorylation and turnover of protein kinase C βII mediated by phosphatidylinositol 3-kinase- and mammalian target of rapamycin- dependent pathways
    • Helliwell PA, Rumsby MG, Kellett GL. Intestinal sugar absorption is regulated by phosphorylation and turnover of protein kinase C βII mediated by phosphatidylinositol 3-kinase- and mammalian target of rapamycin- dependent pathways. J Biol Chem 278: 28644–28650, 2003
    • (2003) J Biol Chem , vol.278 , pp. 28644-28650
    • Helliwell, P.A.1    Rumsby, M.G.2    Kellett, G.L.3
  • 27
    • 34548830731 scopus 로고    scopus 로고
    • Long-term effect of leptin on H_-coupled peptide cotransporter 1 activity and expression in vivo: Evidence in leptin-deficient mice
    • Hindlet P, Bado A, Farinotti R, Buyse M. Long-term effect of leptin on H_-coupled peptide cotransporter 1 activity and expression in vivo: evidence in leptin-deficient mice. J Pharmacol Exp Ther 323: 192–201, 2007
    • (2007) J Pharmacol Exp Ther , vol.323 , pp. 192-201
    • Hindlet, P.1    Bado, A.2    Farinotti, R.3    Buyse, M.4
  • 28
    • 65449119622 scopus 로고    scopus 로고
    • Reduced intestinal absorption of dipeptides viaPepT1 in mice with diet-induced obesity is associated with leptin receptor down-regulation
    • Hindlet P, Bado A, Kamenicky P, Delomenie C, Bourasset F, Nazaret C, Farinotti R, Buyse M. Reduced intestinal absorption of dipeptides viaPepT1 in mice with diet-induced obesity is associated with leptin receptor down-regulation. J Biol Chem 284: 6801–6808, 2009
    • (2009) J Biol Chem , vol.284 , pp. 6801-6808
    • Hindlet, P.1    Bado, A.2    Kamenicky, P.3    Delomenie, C.4    Bourasset, F.5    Nazaret, C.6    Farinotti, R.7    Buyse, M.8
  • 35
    • 55549124572 scopus 로고    scopus 로고
    • Membrane receptorinitiated signaling in 1,25(OH)2D3-stimulated calcium uptake in intestinal epithelial cells
    • Khanal RC, Peters TM, Smith NM, Nemere I. Membrane receptorinitiated signaling in 1,25(OH)2D3-stimulated calcium uptake in intestinal epithelial cells. J Cell Biochem 105: 1109–1116, 2008
    • (2008) J Cell Biochem , vol.105 , pp. 1109-1116
    • Khanal, R.C.1    Peters, T.M.2    Smith, N.M.3    Nemere, I.4
  • 37
    • 78649471913 scopus 로고    scopus 로고
    • Gastrointestinal hormones and the regulation of β-cell mass
    • Lavine JA, Attie AD. Gastrointestinal hormones and the regulation of β-cell mass. Ann NY Acad Sci 1212: 41–58, 2010
    • (2010) Ann NY Acad Sci , vol.1212 , pp. 41-58
    • Lavine, J.A.1    Attie, A.D.2
  • 39
    • 84877633484 scopus 로고    scopus 로고
    • Cholera: Pathophysiology and emerging therapeutic targets
    • Muanprasat C, Chatsudthipong V. Cholera: pathophysiology and emerging therapeutic targets. Future Med Chem 5: 781–798, 2013
    • (2013) Future Med Chem , vol.5 , pp. 781-798
    • Muanprasat, C.1    Chatsudthipong, V.2
  • 41
    • 84856183515 scopus 로고    scopus 로고
    • PKCδ-dependent activation of ERK1/2 leads to upregulation of the human NHE2 transcriptional activity in intestinal epithelial cell line C2BBe1
    • Muthusamy S, Shukla S, Amin MR, Cheng M, Orenuga T, Dudeja PK, Malakooti J. PKCδ-dependent activation of ERK1/2 leads to upregulation of the human NHE2 transcriptional activity in intestinal epithelial cell line C2BBe1. Am J Physiol Gastrointest Liver Physiol 302: G317–G325, 2012
    • (2012) Am J Physiol Gastrointest Liver Physiol , vol.302 , pp. G317-G325
    • Muthusamy, S.1    Shukla, S.2    Amin, M.R.3    Cheng, M.4    Orenuga, T.5    Dudeja, P.K.6    Malakooti, J.7
  • 42
    • 33847700163 scopus 로고    scopus 로고
    • Leptin transcriptionally enhances peptide transporter (hPepT1) expression and activity via the cAMP-response element-binding protein and Cdx2 transcription factors
    • Nduati V, Yan Y, Dalmasso G, Driss A, Sitaraman S, Merlin D. Leptin transcriptionally enhances peptide transporter (hPepT1) expression and activity via the cAMP-response element-binding protein and Cdx2 transcription factors. J Biol Chem 282: 1359–1373, 2007
    • (2007) J Biol Chem , vol.282 , pp. 1359-1373
    • Nduati, V.1    Yan, Y.2    Dalmasso, G.3    Driss, A.4    Sitaraman, S.5    Merlin, D.6
  • 44
    • 0033385964 scopus 로고    scopus 로고
    • Differentiated intestinal epithelial cells exhibit increased migration through polyamines and myosin II
    • Rao JN, Li J, Li L, Bass BL, Wang JY. Differentiated intestinal epithelial cells exhibit increased migration through polyamines and myosin II. Am J Physiol Gastrointest Liver Physiol 277: G1149–G1158, 1999
    • (1999) Am J Physiol Gastrointest Liver Physiol , vol.277 , pp. G1149-G1158
    • Rao, J.N.1    Li, J.2    Li, L.3    Bass, B.L.4    Wang, J.Y.5
  • 46
    • 77952985477 scopus 로고    scopus 로고
    • PI3 kinase and PDK1 in the regulation of the electrogenic intestinal dipeptide transport
    • Rexhepaj R, Rotte A, Pasham V, Gu S, Kempe DS, Lang F. PI3 kinase and PDK1 in the regulation of the electrogenic intestinal dipeptide transport. Cell Physiol Biochem 25: 715–722, 2010
    • (2010) Cell Physiol Biochem , vol.25 , pp. 715-722
    • Rexhepaj, R.1    Rotte, A.2    Pasham, V.3    Gu, S.4    Kempe, D.S.5    Lang, F.6
  • 47
    • 0034053920 scopus 로고    scopus 로고
    • Riboflavin uptake by human-derived colonic epithelial NCM460 cells
    • Said HM, Ortiz A, Moyer MP, Yanagawa N. Riboflavin uptake by human-derived colonic epithelial NCM460 cells. Am J Physiol Cell Physiol 278: C270–C276, 2000
    • (2000) Am J Physiol Cell Physiol , vol.278 , pp. C270-C276
    • Said, H.M.1    Ortiz, A.2    Moyer, M.P.3    Yanagawa, N.4
  • 49
    • 15744363937 scopus 로고    scopus 로고
    • Involvement of c-Src and protein kinase C_ in the inhibition of Cl /OH exchange activity in Caco-2 cells by serotonin
    • Saksena S, Gill RK, Tyagi S, Alrefai WA, Sarwar Z, Ramaswamy K, Dudeja PK. Involvement of c-Src and protein kinase C_ in the inhibition of Cl /OH exchange activity in Caco-2 cells by serotonin. J Biol Chem 280: 11859–11868, 2005
    • (2005) J Biol Chem , vol.280 , pp. 11859-11868
    • Saksena, S.1    Gill, R.K.2    Tyagi, S.3    Alrefai, W.A.4    Sarwar, Z.5    Ramaswamy, K.6    Dudeja, P.K.7
  • 53
    • 36549010103 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide enhances adipocyte development and glucose uptake in part through Akt activation
    • Song DH, Getty-Kaushik L, Tseng E, Simon J, Corkey BE, Wolfe MM. Glucose-dependent insulinotropic polypeptide enhances adipocyte development and glucose uptake in part through Akt activation. Gastroenterology 133: 1796–1805, 2007
    • (2007) Gastroenterology , vol.133 , pp. 1796-1805
    • Song, D.H.1    Getty-Kaushik, L.2    Tseng, E.3    Simon, J.4    Corkey, B.E.5    Wolfe, M.M.6
  • 54
    • 0032959490 scopus 로고    scopus 로고
    • Hormonal regulation of oligopeptide transporter pept-1 in a human intestinal cell line
    • Thamotharan M, Bawani SZ, Zhou X, Adibi SA. Hormonal regulation of oligopeptide transporter pept-1 in a human intestinal cell line. Am J Physiol Cell Physiol 276: C821–C826, 1999
    • (1999) Am J Physiol Cell Physiol , vol.276 , pp. C821-C826
    • Thamotharan, M.1    Bawani, S.Z.2    Zhou, X.3    Adibi, S.A.4
  • 55
    • 84863687906 scopus 로고    scopus 로고
    • Estrogen potentiates prostaglandin E2-stimulated duodenal mucosal HCO3 secretion in mice
    • Tuo B, Wen G, Wang X, Xu J, Xie R, Liu X, Dong H. Estrogen potentiates prostaglandin E2-stimulated duodenal mucosal HCO3 secretion in mice. Am J Physiol Endocrinol Metab 303: E111–E121, 2012
    • (2012) Am J Physiol Endocrinol Metab , vol.303 , pp. E111-E121
    • Tuo, B.1    Wen, G.2    Wang, X.3    Xu, J.4    Xie, R.5    Liu, X.6    Dong, H.7
  • 56
    • 70349236944 scopus 로고    scopus 로고
    • Involvement of phosphatidylinositol 3-kinase in cAMP- and cGMP-induced duodenal epithelial CFTR activation in mice
    • Tuo B, Wen G, Zhang Y, Liu X, Wang X, Dong H. Involvement of phosphatidylinositol 3-kinase in cAMP- and cGMP-induced duodenal epithelial CFTR activation in mice. Am J Physiol Cell Physiol 297: C503–C515, 2009
    • (2009) Am J Physiol Cell Physiol , vol.297 , pp. C503-C515
    • Tuo, B.1    Wen, G.2    Zhang, Y.3    Liu, X.4    Wang, X.5    Dong, H.6
  • 58
    • 34547106079 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase is involved in prostaglandin E2-mediated murine duodenal bicarbonate secretion
    • Tuo BG, Wen GR, Seidler U. Phosphatidylinositol 3-kinase is involved in prostaglandin E2-mediated murine duodenal bicarbonate secretion. Am J Physiol Gastrointest Liver Physiol 293: G279–G287, 2007
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.293 , pp. G279-G287
    • Tuo, B.G.1    Wen, G.R.2    Seidler, U.3
  • 59
    • 0027136670 scopus 로고
    • Gastric inhibitory polypeptide receptor, a member of the secretin-vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain
    • Usdin TB, Mezey E, Button DC, Brownstein MJ, Bonner TI. Gastric inhibitory polypeptide receptor, a member of the secretin-vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain. Endocrinology 133: 2861–2870, 1993
    • (1993) Endocrinology , vol.133 , pp. 2861-2870
    • Usdin, T.B.1    Mezey, E.2    Button, D.C.3    Brownstein, M.J.4    Bonner, T.I.5
  • 61
    • 0033864485 scopus 로고    scopus 로고
    • Protein kinase C isoenzymes: A review of their structure, regulation and role in regulating airways smooth muscle tone and mitogenesis
    • Webb BL, Hirst SJ, Giembycz MA. Protein kinase C isoenzymes: a review of their structure, regulation and role in regulating airways smooth muscle tone and mitogenesis. Br J Pharmacol 130: 1433–1452, 2000
    • (2000) Br J Pharmacol , vol.130 , pp. 1433-1452
    • Webb, B.L.1    Hirst, S.J.2    Giembycz, M.A.3
  • 62
    • 78649371133 scopus 로고    scopus 로고
    • Dietary effects on incretin hormone secretion
    • Wu T, Rayner CK, Jones K, Horowitz M. Dietary effects on incretin hormone secretion. Vitam Horm 84: 81–110, 2011
    • (2011) Vitam Horm , vol.84 , pp. 81-110
    • Wu, T.1    Rayner, C.K.2    Jones, K.3    Horowitz, M.4
  • 63
    • 12244281854 scopus 로고    scopus 로고
    • Physiology of GIP—a lesson from GIP receptor knockout mice
    • Yamada Y, Seino Y. Physiology of GIP—a lesson from GIP receptor knockout mice. Horm Metab Res 36: 771–774, 2004
    • (2004) Horm Metab Res , vol.36 , pp. 771-774
    • Yamada, Y.1    Seino, Y.2
  • 64
    • 0033520869 scopus 로고    scopus 로고
    • GIP biology and fat metabolism
    • Yip RG, Wolfe MM. GIP biology and fat metabolism. Life Sci 66: 91–103, 2000
    • (2000) Life Sci , vol.66 , pp. 91-103
    • Yip, R.G.1    Wolfe, M.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.