-
1
-
-
0023664272
-
Genistein, a specific inhibitor of tyrosine-specific protein kinases
-
Akiyama T, Ishida J, Nakagawa S, Ogawara H, Watanabe S, Itoh N, Shibuya M, Fukami Y. Genistein, a specific inhibitor of tyrosine-specific protein kinases. J Biol Chem 262: 5592-5595, 1987.
-
(1987)
J Biol Chem
, vol.262
, pp. 5592-5595
-
-
Akiyama, T.1
Ishida, J.2
Nakagawa, S.3
Ogawara, H.4
Watanabe, S.5
Itoh, N.6
Shibuya, M.7
Fukami, Y.8
-
2
-
-
85176669361
-
-
Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 270: 27489-27494, 1995.
-
Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 270: 27489-27494, 1995.
-
-
-
-
3
-
-
0029875386
-
Cyclic adenosine-3′,5′-monophosphate production is greater in rabbit duodenal crypt than in villus cells
-
Amelsberg M, Amelsberg A, Ainsworth MA, Hogan DL, Isenberg JI. Cyclic adenosine-3′,5′-monophosphate production is greater in rabbit duodenal crypt than in villus cells. Scand J Gastroenterol 31: 233-239, 1996.
-
(1996)
Scand J Gastroenterol
, vol.31
, pp. 233-239
-
-
Amelsberg, M.1
Amelsberg, A.2
Ainsworth, M.A.3
Hogan, D.L.4
Isenberg, J.I.5
-
5
-
-
0034956087
-
Increased islet viability by addition of beraprost sodium to collagenase solution
-
Arita S, Une S, Ohtsuka S, Kawahara T, Kasraie A, Smith CV, Mullen Y. Increased islet viability by addition of beraprost sodium to collagenase solution. Pancreas 23: 62-67, 2001.
-
(2001)
Pancreas
, vol.23
, pp. 62-67
-
-
Arita, S.1
Une, S.2
Ohtsuka, S.3
Kawahara, T.4
Kasraie, A.5
Smith, C.V.6
Mullen, Y.7
-
6
-
-
1342304124
-
Gs protein-coupled receptor agonists induce transactivation of the epidermal growth factor receptor in T84 cells: Implications for epithelial secretory responses
-
Bertelsen LS, Barrett KE, Keely SJ. Gs protein-coupled receptor agonists induce transactivation of the epidermal growth factor receptor in T84 cells: implications for epithelial secretory responses. J Biol Chem 279: 6271-6279, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 6271-6279
-
-
Bertelsen, L.S.1
Barrett, K.E.2
Keely, S.J.3
-
7
-
-
0037573575
-
Insulin-stimulated trafficking of ENaC in renal cells requires PI 3-kinase activity
-
Blazer-Yost BL, Esterman MA, Vlahos CJ. Insulin-stimulated trafficking of ENaC in renal cells requires PI 3-kinase activity. Am J Physiol Cell Physiol 284: C1645-C1653, 2003.
-
(2003)
Am J Physiol Cell Physiol
, vol.284
-
-
Blazer-Yost, B.L.1
Esterman, M.A.2
Vlahos, C.J.3
-
8
-
-
0041816104
-
2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor
-
2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor. J Biol Chem 278: 35451-35457, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 35451-35457
-
-
Buchanan, F.G.1
Wang, D.2
Bargiacchi, F.3
DuBois, R.N.4
-
9
-
-
0037205048
-
The phosphoinositide 3-kinase pathway
-
Cantley LC. The phosphoinositide 3-kinase pathway. Science 296: 1655-1657, 2002.
-
(2002)
Science
, vol.296
, pp. 1655-1657
-
-
Cantley, L.C.1
-
10
-
-
0017920993
-
Prostaglandin cytoprotection of gastric mucosa
-
Chaudhury TK, Jacobson ED. Prostaglandin cytoprotection of gastric mucosa. Gastroenterology 74: 58-63, 1978.
-
(1978)
Gastroenterology
, vol.74
, pp. 58-63
-
-
Chaudhury, T.K.1
Jacobson, E.D.2
-
12
-
-
0018070384
-
2
-
2. Lancet 2: 1253-1254, 1978.
-
(1978)
Lancet
, vol.2
, pp. 1253-1254
-
-
Cohen, M.M.1
-
14
-
-
0035198746
-
Mucosal defense and repair. Role of prostaglandins in the stomach and duodenum
-
Cryer B. Mucosal defense and repair. Role of prostaglandins in the stomach and duodenum. Gastroenterol Clin North Am 30: 877-894, 2001.
-
(2001)
Gastroenterol Clin North Am
, vol.30
, pp. 877-894
-
-
Cryer, B.1
-
15
-
-
9744240196
-
Ann Oncol 15, Suppl
-
4: iv233-iv239
-
Dancey JE. Molecular targeting: PI3 kinase pathway. Ann Oncol 15, Suppl 4: iv233-iv239, 2004.
-
(2004)
-
-
Dancey, J.E.1
-
17
-
-
0032725634
-
Vasopressin stimulates sodium transport in A6 cells via a phosphatidylinositide 3-kinase-dependent pathway
-
Edinger RS, Rokaw MD, Johnson JP. Vasopressin stimulates sodium transport in A6 cells via a phosphatidylinositide 3-kinase-dependent pathway. Am J Physiol Renal Physiol 277: F575-F579, 1999.
-
(1999)
Am J Physiol Renal Physiol
, vol.277
-
-
Edinger, R.S.1
Rokaw, M.D.2
Johnson, J.P.3
-
18
-
-
0035258047
-
Gastroduodenal mucosal alkaline secretion and mucosal protection
-
Flemstrom G, Isenberg JI. Gastroduodenal mucosal alkaline secretion and mucosal protection. News Physiol Sci 16: 23-28, 2001.
-
(2001)
News Physiol Sci
, vol.16
, pp. 23-28
-
-
Flemstrom, G.1
Isenberg, J.I.2
-
20
-
-
0037809229
-
2 induced functional expression of early growth response factor-1 by EP4, but not EP2, prostanoid receptors via the phosphatidylinositol 3-kinase and extracellular signal-regulated kinases
-
2 induced functional expression of early growth response factor-1 by EP4, but not EP2, prostanoid receptors via the phosphatidylinositol 3-kinase and extracellular signal-regulated kinases. J Biol Chem 278: 12151-12156, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 12151-12156
-
-
Fujino, H.1
Xu, W.2
Regan, J.W.3
-
21
-
-
0042734625
-
Prostanoid receptors and phosphatidylinositol 3-kinase: A pathway to cancer?
-
Fujino H, Regan JW. Prostanoid receptors and phosphatidylinositol 3-kinase: a pathway to cancer? Trends Pharmacol Sci 24: 335-340, 2003.
-
(2003)
Trends Pharmacol Sci
, vol.24
, pp. 335-340
-
-
Fujino, H.1
Regan, J.W.2
-
22
-
-
30044434401
-
EP4 prostanoid receptor coupling to a pertussis toxin-sensitive inhibitory G protein
-
Fujino H, Regan JW. EP4 prostanoid receptor coupling to a pertussis toxin-sensitive inhibitory G protein. Mol Pharmacol 69: 5-10, 2006.
-
(2006)
Mol Pharmacol
, vol.69
, pp. 5-10
-
-
Fujino, H.1
Regan, J.W.2
-
24
-
-
0031914609
-
Modulation of bicarbonate secretion in rabbit duodenum: The role of calcium
-
Hogan DL, Yao B, Isenberg JI. Modulation of bicarbonate secretion in rabbit duodenum: the role of calcium. Dig Dis Sci 43: 120-125, 1998.
-
(1998)
Dig Dis Sci
, vol.43
, pp. 120-125
-
-
Hogan, D.L.1
Yao, B.2
Isenberg, J.I.3
-
25
-
-
12344257663
-
Alpha1A-adrenoceptors activate glucose uptake in L6 muscle cells through a phospholipase C-, phosphatidylinositol-3 kinase-, and atypical protein kinase C-dependent pathway
-
Hutchinson DS, Bengtsson T. Alpha1A-adrenoceptors activate glucose uptake in L6 muscle cells through a phospholipase C-, phosphatidylinositol-3 kinase-, and atypical protein kinase C-dependent pathway. Endocrinology 146: 901-912, 2005.
-
(2005)
Endocrinology
, vol.146
, pp. 901-912
-
-
Hutchinson, D.S.1
Bengtsson, T.2
-
26
-
-
0031783921
-
Protein kinase G expression in the small intestine and functional importance for smooth muscle relaxation
-
Huber A, Trudrung P, Storr M, Franck H, Schusdziarra V, Ruth P, Allescher HD. Protein kinase G expression in the small intestine and functional importance for smooth muscle relaxation. Am J Physiol Gastrointest Liver Physiol 275: G629-G637, 1998.
-
(1998)
Am J Physiol Gastrointest Liver Physiol
, vol.275
-
-
Huber, A.1
Trudrung, P.2
Storr, M.3
Franck, H.4
Schusdziarra, V.5
Ruth, P.6
Allescher, H.D.7
-
28
-
-
0023139121
-
Impaired proximal duodenal mucosal bicarbonate secretion in patients with duodenal ulcer
-
Isenberg JI, Selling JA, Hogan DL, Koss MA. Impaired proximal duodenal mucosal bicarbonate secretion in patients with duodenal ulcer. N Engl J Med 316: 374-379, 1987.
-
(1987)
N Engl J Med
, vol.316
, pp. 374-379
-
-
Isenberg, J.I.1
Selling, J.A.2
Hogan, D.L.3
Koss, M.A.4
-
29
-
-
0020010838
-
Prostaglandin and protection of the gastroduodenal mucosa
-
Johansson C, Bergstrom S. Prostaglandin and protection of the gastroduodenal mucosa. Scand J Gastroenterol Suppl 77: 21-46, 1982.
-
(1982)
Scand J Gastroenterol Suppl
, vol.77
, pp. 21-46
-
-
Johansson, C.1
Bergstrom, S.2
-
30
-
-
4644356857
-
Duodenal alkaline secretion: Its mechanisms and role in mucosal protection against gastric acid
-
Konturek PC, Konturek SJ, Hahn EG. Duodenal alkaline secretion: its mechanisms and role in mucosal protection against gastric acid. Dig Liver Dis 36: 505-512, 2004.
-
(2004)
Dig Liver Dis
, vol.36
, pp. 505-512
-
-
Konturek, P.C.1
Konturek, S.J.2
Hahn, E.G.3
-
31
-
-
0022538503
-
Role of endogenous prostaglandins in duodenal alkaline response to luminal hydrochloric acid or arachidonic acid in conscious dogs
-
Konturek SJ, Bilski J, Tasler J, Konturek JW, Bielanski W, Kaminska A. Role of endogenous prostaglandins in duodenal alkaline response to luminal hydrochloric acid or arachidonic acid in conscious dogs. Digestion 34: 268-274, 1986.
-
(1986)
Digestion
, vol.34
, pp. 268-274
-
-
Konturek, S.J.1
Bilski, J.2
Tasler, J.3
Konturek, J.W.4
Bielanski, W.5
Kaminska, A.6
-
32
-
-
0345866804
-
The inhibitory effect of adrenomedullin in the rat ileum: Cross-talk with beta3-adrenoceptor in the serotonin-induced muscle contraction
-
Kravtsov GM, Hwang IS, Tang F. The inhibitory effect of adrenomedullin in the rat ileum: cross-talk with beta3-adrenoceptor in the serotonin-induced muscle contraction. J Pharmacol Exp Ther 308: 241-248, 2004.
-
(2004)
J Pharmacol Exp Ther
, vol.308
, pp. 241-248
-
-
Kravtsov, G.M.1
Hwang, I.S.2
Tang, F.3
-
33
-
-
25844483661
-
Duodenal secretion in humans mediated by the EP4 receptor subtype
-
Larsen R, Hansen MB, Bindslev N. Duodenal secretion in humans mediated by the EP4 receptor subtype. Acta Physiol Scand 185: 133-140, 2005.
-
(2005)
Acta Physiol Scand
, vol.185
, pp. 133-140
-
-
Larsen, R.1
Hansen, M.B.2
Bindslev, N.3
-
34
-
-
0035903178
-
+ exchanger 3
-
+ exchanger 3. J Biol Chem 276: 31296-31304, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 31296-31304
-
-
Lee-Kwon, W.1
Johns, D.C.2
Cha, B.3
Cavet, M.4
Park, J.5
Tsichlis, P.6
Donowitz, M.7
-
35
-
-
0028845631
-
Indomethacin decreases gastroduodenal mucosal bicarbonate secretion in humans
-
Mertz-Nielsen A, Hillingso J, Bukhave K, Rask-Madsen J. Indomethacin decreases gastroduodenal mucosal bicarbonate secretion in humans. Scand J Gastroenterol 30: 1160-1165, 1995.
-
(1995)
Scand J Gastroenterol
, vol.30
, pp. 1160-1165
-
-
Mertz-Nielsen, A.1
Hillingso, J.2
Bukhave, K.3
Rask-Madsen, J.4
-
36
-
-
0026611438
-
1 cytoprotection against CCl4-induced necrosis in isolated rat liver cells
-
1 cytoprotection against CCl4-induced necrosis in isolated rat liver cells. Res Commun Chem Pathol Pharmacol 75: 173-184, 1992.
-
(1992)
Res Commun Chem Pathol Pharmacol
, vol.75
, pp. 173-184
-
-
Mihas, A.A.1
-
37
-
-
0027141041
-
Bicarbonate secretion in rabbit ileum: Electrogenicity, ion dependence, and effects of cyclic nucleotides
-
Minhas BS, Sullivan SK, Field M. Bicarbonate secretion in rabbit ileum: electrogenicity, ion dependence, and effects of cyclic nucleotides. Gastroenterology 105: 1617-1629, 1993.
-
(1993)
Gastroenterology
, vol.105
, pp. 1617-1629
-
-
Minhas, B.S.1
Sullivan, S.K.2
Field, M.3
-
38
-
-
0031004904
-
Cellular localization of mRNAs for prostaglandin E receptor subtypes in mouse gastrointestinal tract
-
Morimoto K, Sugimoto Y, Katsuyama M, Oida H, Tsuboi K, Kishi K, Kinoshita Y, Negishi M, Chiba T, Narumiya S, Ichikawa A. Cellular localization of mRNAs for prostaglandin E receptor subtypes in mouse gastrointestinal tract. Am J Physiol Gastrointest Liver Physiol 272: G681-G687, 1997.
-
(1997)
Am J Physiol Gastrointest Liver Physiol
, vol.272
-
-
Morimoto, K.1
Sugimoto, Y.2
Katsuyama, M.3
Oida, H.4
Tsuboi, K.5
Kishi, K.6
Kinoshita, Y.7
Negishi, M.8
Chiba, T.9
Narumiya, S.10
Ichikawa, A.11
-
40
-
-
0027319296
-
Cholinergic regulation of guinea pig duodenal bicarbonate secretion
-
Odes HS, Muallem R, Beil W, Schwenk M, Sewing KF. Cholinergic regulation of guinea pig duodenal bicarbonate secretion. Am J Physiol Gastrointest Liver Physiol 265: G270-G276, 1993.
-
(1993)
Am J Physiol Gastrointest Liver Physiol
, vol.265
-
-
Odes, H.S.1
Muallem, R.2
Beil, W.3
Schwenk, M.4
Sewing, K.F.5
-
41
-
-
13844273087
-
PI3K-Akt pathway: Its functions and alterations in human cancer
-
Osaki M, Oshimura M, Ito H. PI3K-Akt pathway: its functions and alterations in human cancer. Apoptosis 9: 667-676, 2004.
-
(2004)
Apoptosis
, vol.9
, pp. 667-676
-
-
Osaki, M.1
Oshimura, M.2
Ito, H.3
-
42
-
-
0028217223
-
Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase
-
Powis G, Bonjouklian R, Berggren MM, Gallegos A, Abraham R, Ashendel C, Zalkow L, Matter WF, Dodge J, Grindey G. Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase. Cancer Res 54: 2419-2423, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 2419-2423
-
-
Powis, G.1
Bonjouklian, R.2
Berggren, M.M.3
Gallegos, A.4
Abraham, R.5
Ashendel, C.6
Zalkow, L.7
Matter, W.F.8
Dodge, J.9
Grindey, G.10
-
43
-
-
0026464444
-
Effects of EP-receptor subtype specific agonists and other prostanoids on adenylate cyclase activity of duodenal epithelial cells
-
Reimer R, Heim HK, Muallem R, Odes HS, Sewing KF. Effects of EP-receptor subtype specific agonists and other prostanoids on adenylate cyclase activity of duodenal epithelial cells. Prostaglandins 44: 485-493, 1992.
-
(1992)
Prostaglandins
, vol.44
, pp. 485-493
-
-
Reimer, R.1
Heim, H.K.2
Muallem, R.3
Odes, H.S.4
Sewing, K.F.5
-
45
-
-
0018292487
-
Cytoprotection by prostaglandins
-
Robert A. Cytoprotection by prostaglandins. Gastroenterology 77:761-767, 1979.
-
(1979)
Gastroenterology
, vol.77
, pp. 761-767
-
-
Robert, A.1
-
46
-
-
20244385114
-
2 protects isolated cells against injury through multiple mechanisms
-
2 protects isolated cells against injury through multiple mechanisms. Gastroenterol Jpn 28, Suppl 5: 122-126, 1993.
-
(1993)
Gastroenterol Jpn
, vol.28
, Issue.SUPPL. 5
, pp. 122-126
-
-
Sakamoto, C.1
Matsuda, K.2
Konda, Y.3
Nishisaki, H.4
Nakano, O.5
Matozaki, T.6
Wada, K.7
Suzuki, T.8
Uchida, T.9
Noguchi, H.10
-
47
-
-
0033963462
-
Insulin stimulates NHE1 activity by sequential activation of phosphatidylinositol 3-kinase and protein kinase C zeta in human erythrocytes
-
Sauvage M, Maziere P, Fathallah H, Giraud F. Insulin stimulates NHE1 activity by sequential activation of phosphatidylinositol 3-kinase and protein kinase C zeta in human erythrocytes. Eur J Biochem 267: 955-962, 2000.
-
(2000)
Eur J Biochem
, vol.267
, pp. 955-962
-
-
Sauvage, M.1
Maziere, P.2
Fathallah, H.3
Giraud, F.4
-
48
-
-
0031450718
-
- secretion
-
- secretion. J Physiol 505: 411-423, 1997.
-
(1997)
J Physiol
, vol.505
, pp. 411-423
-
-
Seidler, U.1
Blumenstein, I.2
Kretz, A.3
Viellard-Baron, D.4
Rossmann, H.5
Colledge, W.H.6
Evans, M.7
Ratcliff, R.8
Gregor, M.9
-
51
-
-
0034995665
-
Role of endogenous nitric oxide and prostaglandin in duodenal bicarbonate response induced by mucosal acidification in rats
-
Sugamoto S, Kawauch S, Furukawa O, Mimaki TH, Takeuchi K. Role of endogenous nitric oxide and prostaglandin in duodenal bicarbonate response induced by mucosal acidification in rats. Dig Dis Sci 46: 1208-1216, 2001.
-
(2001)
Dig Dis Sci
, vol.46
, pp. 1208-1216
-
-
Sugamoto, S.1
Kawauch, S.2
Furukawa, O.3
Mimaki, T.H.4
Takeuchi, K.5
-
52
-
-
0032744699
-
Impaired duodenal bicarbonate secretion and mucosal integrity in mice lacking prostaglandin E-receptor subtype EP3
-
Takeuchi K, Ukawa H, Kato S, Furukawa O, Araki H, Sugimoto Y, Ichikawa A, Ushikubi F, Narumiya S. Impaired duodenal bicarbonate secretion and mucosal integrity in mice lacking prostaglandin E-receptor subtype EP3. Gastroenterology 117: 1128-1135, 1999.
-
(1999)
Gastroenterology
, vol.117
, pp. 1128-1135
-
-
Takeuchi, K.1
Ukawa, H.2
Kato, S.3
Furukawa, O.4
Araki, H.5
Sugimoto, Y.6
Ichikawa, A.7
Ushikubi, F.8
Narumiya, S.9
-
53
-
-
0030733758
-
Roles of prostaglandin E-receptor subtypes in gastric and duodenal bicarbonate secretion in rats
-
Takeuchi K, Yagi K, Kato S, Ukawa H. Roles of prostaglandin E-receptor subtypes in gastric and duodenal bicarbonate secretion in rats. Gastroenterology 113: 1553-1559, 1997.
-
(1997)
Gastroenterology
, vol.113
, pp. 1553-1559
-
-
Takeuchi, K.1
Yagi, K.2
Kato, S.3
Ukawa, H.4
-
55
-
-
0042825763
-
Effect of 5-hydroxytryptamine on duodenal mucosal bicarbonate secretion in mice
-
Tuo BG, Isenberg JI. Effect of 5-hydroxytryptamine on duodenal mucosal bicarbonate secretion in mice. Gastroenterology 125: 805-814, 2003.
-
(2003)
Gastroenterology
, vol.125
, pp. 805-814
-
-
Tuo, B.G.1
Isenberg, J.I.2
-
56
-
-
1342301691
-
-
4 receptors in mice. Am J Physiol Gastrointest Liver Physiol 286: G444-G451, 2004.
-
4 receptors in mice. Am J Physiol Gastrointest Liver Physiol 286: G444-G451, 2004.
-
-
-
-
58
-
-
0026615055
-
2 prostaglandins modulate cell proliferation in the small intestinal epithelium of the rat
-
2 prostaglandins modulate cell proliferation in the small intestinal epithelium of the rat. Digestion 52: 157-164, 1992.
-
(1992)
Digestion
, vol.52
, pp. 157-164
-
-
Uribe, A.1
Alam, M.2
Midtvedt, T.3
-
60
-
-
0028170210
-
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1- benzopyran-4-one (LY294002)
-
Vlahos CJ, Matter WF, Hui KY, Brown RF. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1- benzopyran-4-one (LY294002). J Biol Chem 269: 5241-5248, 1994.
-
(1994)
J Biol Chem
, vol.269
, pp. 5241-5248
-
-
Vlahos, C.J.1
Matter, W.F.2
Hui, K.Y.3
Brown, R.F.4
-
61
-
-
0026095297
-
Role of prostaglandins in gastroduodenal mucosal protection
-
Wilson DE. Role of prostaglandins in gastroduodenal mucosal protection. J Clin Gastroenterol 13, Suppl 1: S65-S71, 1991.
-
(1991)
J Clin Gastroenterol
, vol.13
, Issue.SUPPL. 1
-
-
Wilson, D.E.1
-
62
-
-
0042734621
-
Phosphoinositide 3-kinase signalling - which way to target?
-
Wymann MP, Zvelebil M, Laffargue M. Phosphoinositide 3-kinase signalling - which way to target? Trends Pharmacol Sci 24: 366-376, 2003.
-
(2003)
Trends Pharmacol Sci
, vol.24
, pp. 366-376
-
-
Wymann, M.P.1
Zvelebil, M.2
Laffargue, M.3
-
63
-
-
0027411516
-
2, and cyclic adenosine monophosphate
-
2, and cyclic adenosine monophosphate. Gastroenterology 104: 732-740, 1993.
-
(1993)
Gastroenterology
, vol.104
, pp. 732-740
-
-
Yao, B.1
Hogan, D.L.2
Bukhave, K.3
Koss, M.A.4
Isenberg, J.I.5
|